Following the publication of Mary Wollstonecraft’s Vindication of the Rights of Woman (1792), the women’s suffrage campaign was forged around the slogan “on the same terms as men”. The suffrage, though restricted at the time to men, was gradually extended to include some workers (1867), farm workers who were heads of households (1885) and finally all men, with the advent of universal male suffrage in 1918. In 1884, those wives who now had control over their own bodies, joined single women in demanding representation and the right to vote at local and national level. Citing their irrefutable status as citizens in their own right, British women opposed and denounced the clear injustice of biological arguments used to justify political inequality. In calling for social and political reform based on the equality of the sexes, such women asserted both their status as political subjects and their place in history. In so doing, they called on the state to provide financial assistance to poorer pregnant women and to take action in the struggle against wage inequality and the doctrine of “separate spheres”. Women’s history in the 1970s, and gender history in the 1980s, precipitated the emergence of new approaches in the vast majority of academic fields. Gender inequalities – linked to themes such as masculinities, consent or sexual violence – are thus constitutive of history.
Adverse childhood experiences (ACEs)—such as abuse, neglect, and household dysfunction before age 18—pose substantial risks to individual health and well-being throughout life, but relatively less research has examined how ACEs are associated with parenting behaviors or children’s home environments. We use linked mother–child data from the National Longitudinal Survey of Youth 1979, a U.S. longitudinal cohort study, to investigate how maternal ACEs are associated with the emotional support and cognitive stimulation of children. Regression results demonstrate an inverse relationship between maternal ACE exposure and the degree of emotional support and cognitive stimulation in children’s home environments. Children born to mothers with four or more ACEs had, on average, 4.9 percentile-unit lower emotional support scores and 5.6 percentile-unit lower cognitive stimulation scores relative to mothers with no ACE exposure, net of maternal and child sociodemographic characteristics. Further results document the importance of emotional neglect and physical abuse, both of which were independently and negatively related to the emotional support and cognitive stimulation of children. Our article builds on a growing body of literature by documenting links between maternal ACE exposure and children’s home environments and by illuminating the lengthy intergenerational reach of parental ACEs.
O. G. Sarkisyan, V. A. Razdorov, E. V. Andreev
et al.
Diabetic foot syndrome (DFS) is a dangerous complication of diabetes mellitus. Despite numerous studies dedicated to the wound healing process in patients with diabetic foot syndrome, surgeries in this pathology are often accompanied by surgical suture failure due to insulin therapy and require repeat surgical intervention. The aim of this study is to analyze the biochemical mechanisms involved in the wound healing process in patients with diabetic foot syndrome. To achieve this goal, articles from foreign databases such as PubMed, MedLine, Google Scholar, and the Russian Index of Scientific Citation (RISC) were selected and analyzed for the period from 2017 to 2023. The search was conducted using keywords such as diabetic foot, wound healing, molecular mechanisms, and their Russian equivalents. A total of 74 publications were identified through the literature search, of which 24 literature sources from 2017 to 2023 were included in the review, corresponding to the direction and purpose of the study. In addition, 18 sources older than 2017 were used to reveal the subject of the study from the references in the literature lists. The literature review discusses various factors that influence the wound healing process: the function of the skin barrier, activity of immune system components, as well as the contribution of hypoxia and endothelial dysfunction to tissue regeneration mechanisms in patients with DFS. Despite the available literature data, it is advisable to search for new factors involved in the development mechanisms of DFS to prevent complications and increase the effectiveness of treatment.
Till Koebe, Zinnya del Villar, Brahmani Nutakki
et al.
Abstract Child pornography—better known as child sexual abuse material (CSAM)—represents a severe form of exploitation and victimization of children, leaving the victims with emotional and physical trauma. In this study, we aim to analyze local patterns of CSAM consumption across 1341 French communes in 20 metropolitan regions of France between March 16 to May 31, 2019 using fine-grained mobile traffic data of Tor network-related web services. We estimate that approx. 0.08% of Tor mobile download traffic observed in France is linked to the consumption of CSAM by correlating it with local-level temporal porn consumption patterns. This compares to 0.19% of what we conservatively estimate to be the share of CSAM content in global Tor traffic. In line with existing literature on the link between sexual child abuse and the consumption of image-based content thereof, we observe a positive and statistically significant effect of our CSAM consumption estimates on the reported number of victims of sexual violence and vice versa, which validates our findings, after controlling for a set of geographically disaggregated features including socio-demographic characteristics, voting behavior, nearby points of interest and Google Trends queries. While this is a first, exploratory attempt to look at CSAM from a spatial epidemiological angle, we believe this research provides public health officials with valuable information to prioritize target areas for public awareness campaigns as another step to fulfill the global community’s pledge to target 16.2 of the sustainable development goals: “end abuse, exploitation, trafficking and all forms of violence and torture against children".
History of scholarship and learning. The humanities, Social Sciences
In the current higher education context, the development of academics’ competencies seems to be a crucial issue, with a strong focus on teaching, learning and assessment digital skills (Redecker & Punie, 2017). In connection with the framework of DigCompEdu (2017), it seems important to understand how to better sustain academics’ new professionalisation as Digital Scholars (Weller, 2011) in order to structure efficient and effective academic development models aimed at fostering new teaching skills required at university in the post pandemic era.
Alnakhli Naseer, Salman Mo, Steven C. Olsen
et al.
Background: <i>Brucella melitensis</i> is recognized as one of the predominant zoonotic pathogens globally. Live-attenuated vaccine Rev 1 is currently the most effective vaccine for controlling <i>B. melitensis</i> in small ruminants. While <i>Brucella</i> inactivated, nanoparticle, and subunit vaccines are less effective and require multiple doses, live-attenuated vaccines are less expensive and more efficacious. Several drawbacks are associated with the administration of current attenuated <i>B. melitensis</i> vaccines, including interference with serological diagnostic tests, inducing abortion in pregnant animals, shedding in milk, and zoonotic infections in humans. In this systematic review, we summarize the current literature (1970–2022) on <i>B. melitensis</i> vaccines and review their advantages and disadvantages in order to support the rationale for a need for new or improved small ruminant brucellosis vaccines. Methods: A systematic search was carried out in Web of Science, CAB Abstracts, and PubMed. The original articles describing the <i>B. melitensis</i> vaccines were included. Review articles, articles not published in English, articles that did not offer full text, editorials, correspondences, case reports, case series, diagnostic tests, duplicate publications, and other <i>Brucella</i> vaccines (e.g., <i>B. abortus</i> and <i>B. suis</i>) were excluded. Results: Out of 3700 studies, we identified 18 articles that evaluated <i>B. meltensis</i> vaccines, including recombinant <i>B. melitensis</i> strains (16MΔhfq, 16MΔTcfSR, M5-90ΔmanB, LVM31, M5-90ΔvjbR, 16MΔmucR, ΔznuA, M5-90Δpgm, M5-90ΔwboA), live <i>B. melitensis</i> strain (Rev 1), nanoparticle vaccines (<i>B. melitensis</i> 16M, <i>B. melitensis</i> OMP 31, FliC protein—Mannosylated Chitosan Nanoparticles (FliC and FliC-MCN), <i>B. melitensis</i> and <i>B. abortus</i> combined, and <i>B. melitensis</i> 16M nanoparticles combined with oligopolysaccharide), subunit vaccines (outer membrane vesicles or outer membrane proteins), and a DNA vaccine based on <i>B. melitensis</i> outer membrane proteins (Omp25 and Omp31). The results from these studies revealed that these vaccines can induce humoral and cellular responses and reduce macrophage survival. However, most of these vaccines were evaluated only in murine models, which may not accurately reflect how they work in natural hosts. Conclusions: The high prevalence of <i>B. melitensis</i> in humans and animals remains an issue in many parts of the world. Human brucellosis can be prevented by controlling brucellosis in livestock using vaccination and test-and-removal strategies. Prospective vaccines have limitations, including interference with serodiagnostics after vaccination, virulence in humans and animals, the requirement of booster vaccinations, and insufficient efficacy in preventing infection or abortion. Moreover, most of these vaccines have been assessed in mice models, which have failed to predict immunogenicity or efficacy in natural hosts. Because of these limitations and the re-emergence of <i>B. melitensis</i> worldwide with a high incidence of human infection, our review suggests a need for additional research into the molecular pathology and immunological properties of <i>B. melitensis</i> infection and the identification of protective epitopes or genes that would allow for the development of improved vaccines for small ruminants.
Extant research addressing the relations between TikTok videos and sustainable apparel consumption behavior is limited. This study explores these relations by testing the following theories and constructs: social consciousness, prior sustainable apparel purchasing, attitude toward TikTok videos (featuring sustainable apparel content), and theory of planned behavior. Results from an online survey supported the proposed conceptual framework, suggesting that cognitive, affective, and behavioral factors relevant to sustainable apparel consumption had a positive influence on sustainable apparel purchase intention.
The phrase citizen science is certainly appealing, especially for many of us who have championed the notion of increasing public engagement in science. Citizen science refers most often to projects in which non-scientists provide some of the labor needed for the collection of scientific data, often in environmental research contexts. This involvement provides volunteer workers in support of science while in turn, ideally, offering rewarding and educational participation opportunities for the volunteers. An early U.S. model for citizen participation has been the Cornell University ornithology laboratory, where the recruitment of a widely dispersed army of bird watchers and other non-scientist citizens continues to assist with bird population research and related studies.
But the specific phrase citizen science also conjures up the idea of a sort of participatory democracy operating in the service of science, allowing fresh ideas to bubble up and their policy implications to receive thoughtful attention and popular feedback early on (or, as we later learned to say, «upstream»). It might also suggest science that operates more clearly in the service of society, taking research direction from what its citizens (as community members) actually have to say. This train of thought brings citizen science closer to the idea of community-based participatory research, in which scientific goals are defined in part by communities outside of science itself. The emergence of university-based «science shops», more a European than an American phenomenon, is another close cousin in which scientists allow communities to suggest research problems that reflect community needs.
This issue of Metode presents a series of cases that illustrate both the concept and its divergent objectives: facilitating communication between scientists and non-scientists, raising public interest in science and levels of science literacy, empowering the pursuit of public policy goals, and even pushing the boundaries of social science theory. Younger participants in particular might be motivated to consider alternative career paths, potentially increasing diversity among scientific professionals. Collectively, these goals represent an ambitious agenda for the future through the advancement of frontiers in communication, education, and politics – as well as science itself. And these intriguing cases are still only a handful among many.
Who is a «citizen» and in what sense can they actually «do science»? In the early days of scientific journals, most authors were gentlemen of status. Must a citizen scientist of our own time likewise be a gentleman of status? That certainly does not seem right or fair. Yet, at the same time, the idea that «just anyone» can do science is just not quite right either. Both scientific expertise and scientific authority still matter, especially in the era of climate and COVID where misinformation is often said to be rampant – and is potentially deadly. Given that, what exactly is the role of «citizen scientists»? How do we balance the need for scientific rigor with the need for community involvement (in both directions)? This is a question with no obvious answer.
The idea of citizen science (or amateur science before it) brings with it tensions about the social nature of scientific truth, both the «citizen» part and the «science» part. As Bryan Wynne’s well-known 1989 paper on post-Chernobyl sheep farming argued, radiation scientists had one form of expertise but others (the farmers) had other forms, such as their knowledge of sheep lifecycles, seasons, pastures, and markets. Solutions to managing radiation pollution on sheep farms required both forms.
And yet scientific truth is still established by scientific consensus, not by public opinion or even public participation. In this era of «alternative facts», where it almost seems as though everyone gets to make up their own reality, assisted in no small measure by the dynamics of social media, we are regularly pushed to defend the authority of science. To do that, we need allies. I believe that one productive way of thinking about «citizen scientists» is that they are, or can become, exactly those needed allies, linking communities and societies to the fruits of scientific expertise in the form of knowledge. We should think of the role of citizen scientists not only as gathering data for the «actual» scientists to make use of, but also serving as community opinion leaders on science-related topics.
Communication. Mass media, Information resources (General)
Preocupadas por la materialidad del lenguaje y por su vínculo con los cuerpos, las novelas Salón de belleza de Mario Bellatin y Balnearios de Etiopía de Javier Guerrero se dedican a explorar los lugares de encierro que se organizan alrededor de la enfermedad y las mutaciones y tiempos intempestivos de lo viviente que inauguran posibilidades de resistencia. Si los saberes y prácticas de la medicina aspiran a la clasificación y homogeneización de los cuerpos, estas ficciones desarman tales pretensiones para atender especialmente a las líneas de contagio que configura la enfermedad y a los encuentros entre materias que horadan cualquier voluntad de saber. Ambas narraciones problematizan las formas en que los cuerpos, sus desórdenes y sus padecimientos se convierten en objeto de variadas tecnologías de poder y saber, así como en terreno de luchas por otros modos de vida y otros lenguajes.
Major public projects in Laos are faced with multiple challenges, including project identification and its decision-making. Generally, an identification is an important key identifying the potential needs and requirements for achieving the development goal. However, the process was developed without a formal framework and assurance tools that have been criticized for negative social and environmental consequences as “white elephant projects” over the past few years. Considering this context, the study aimed to develop a conceptual framework to navigate an alternative solution for the right project. Based on contextual analysis and systematic literature review, the proposed framework provided the process of concept development and its assurance that it could be systematically developed in a cause-effect chain of needs. The findings indicate areas that reflect new insights of both strategic performance and a governance system, and reforms the decision-making process in providing new knowledge, new rules, and procedures for effective governance.
Engineering (General). Civil engineering (General), City planning
Since the beginning of the COVID-19 pandemic, public discourse has been characterized by a massive use of war metaphors. At the same time, this use has been harshly attacked as inappropriate and potentially dangerous. The article proposes a reflection on this debate by questioning the demonization of the war metaphor. Indeed, the appropriateness and the efficacy of a metaphor are not absolute values but depend on many factors such as context, audience and communicative purposes. Therefore, instead of attacking war metaphors it would be more useful to enrich the range of expressions to talk about the pandemic. What is really important is to never forget that expressive choices are never only words but a constitutive part of our experience of the world.
Communication. Mass media, Social sciences (General)
The article deals with the concept of culture as a cosmocracy, which is put forward in the works of Valerian Muraviev, one of the leading representatives of the 1920s cosmism. It presents the evolution of Muraviev’s view on the phenomenon of culture from the early articles to the philosophical mysteries “Sophia and the Centaur” and “The Culture of the Future.” The connection of Muraviev’s constructions with the projective philosophy of Nikolay Fedorov, the ancestor of cosmism, with the idea of the antientropical essence of culture, which is characteristic of the representatives of cosmism, is shown.
Interference instead of Belatedness – Polysystem Theory as a Descriptive Model for ‘Small’ Literatures. Luxembourg literature can be considered a ‘small’ literature from various angles. Its small size, young age and the existence of a sparsely diffused language within a multilingual setting are features that also apply to other small European literary systems and that affect their self-perception fundamentally. In that context, Jeanne E. Glesener has identified a “discourse on smallness” which is developed by the literary centres and unconsciously internalized by the actors of small literary systems themselves: this discourse is essentially shaped by the ideas of creative sterility, poor visibility and, particularly, literary belatedness. However, as Glesener points out with respect to Pascale Casanova’s concept of literary time, the notion of belatedness wrongly implies that all literary systems sooner or later generate the same literary phenomena; it is therefore highly problematic. This paper introduces Itamar Even-Zohar’s polysystem theory – which has been designed in view of the Israeli literary system – as an alternative descriptive model for ‘small’ and multilingual literatures. Proceeding from the example of Luxembourg ‘Heimatliteratur’ in the second half of the 20th century, I would like to argue that by openly acknowledging every system’s historical and sociological characteristics and by excluding the notion of comparison from the analysis, the concept of ‘polysystemic interference’ allows for a more neutral study of literary contacts and literary change.
Aida Suellen Galvão Lima, José Guilherme de Oliveira Castro
Qual a importância das narrativas orais na construção da história de um lugar? Com pesquisas realizadas no bairro Centro, em Paragominas-PA, por meio das narrativas orais de seus moradores, pretende-se analisar o papel do imigrante pioneiro na construção histórica da cidade. De forma mais específica, pela análise das narrativas orais contadas por eles, busca-se discutir de que forma essas narrativas podem conter elementos históricos que as tornem importantes e passíveis de serem registradas no âmbito dos estudos históricos oficiais. E nesse aspecto, percebe-se que, em estudos históricos e oficiais, as narrativas orais perdem seus caracteres relevantes nos registros, porém deve-se levar em consideração que as memórias narradas também são formas históricas, além de práticas essenciais em qualquer sociedade; capazes de estabelecer vínculos, registros, construir identidades coletivas e reafirmar o próprio pertencimento no novo lugar escolhido.
It is evident from this research; It is a result of the Ottoman administrative divisions through which Jabal Amel became administratively affiliated to the Beirut state, and after the Nabatiyeh District was established; Jabal Amel became of relative importance in the eyes of the authorities, especially when Rida al-Sulh was appointed there, so Jabal Amel became a center for some political activities. With the issuance of some reform laws by the Ottoman Empire, such as Sharif Humayun’s handwriting of 1856, and the Knowledge Law of 1869, this helped some religions and sects in Jabal Amel expand the establishment of reform institutions.
History of scholarship and learning. The humanities, Arts in general
Objectives: Generic preference-based measures such as EQ-5D are widely used to estimate quality-adjusted life-years but may not be available or, more importantly, appropriate in some medical conditions. Condition-specific preference-based measures (CSPBMs) provide an alternative to generic measures that may be more relevant in some conditions. This project conducted five studies to examine issues in the development and use of CSPBMs: (1) literature review of measures; (2) deriving health states values for classifications with highly correlated dimensions; (3) impact of condition labelling; (4) impact of add-on dimensions; and (5) comparative performance of measures. Design: (1) Systematic search and literature review; (2) and (5) psychometric analyses on existing data; (2), (3) and (4) valuation surveys and survey analyses. Setting: Valuation surveys conducted using face-to-face interviews in the respondents’ homes. Participants: Valuation surveys conducted using representative samples of the UK general population. Interventions: Not applicable. Main outcome measures: The project developed a CSPBM CORE-6D and analyses AQL-5D, CORE-6D, EORTC-8D, EQ-5D, OAB-5D and SF-6D data. Results: (1) There was substantial variability in methods used to develop CSPBMs. (2) A new method for generating states using Rasch analysis was undertaken, which successfully dealt with the problem of highly correlated domains. (3) Condition labels affected utility values but this was dependent on the condition and severity of the health state. (4) Adding on an extra dimension affected health-state values and preference weights for other dimensions. (5) The performance of CSPBMs was comparable with that of their parent instrument and of generic preference-based measures with better performance for discrimination between severity groups. Conclusions: CSPBMs have an important role for economic evaluation, for which generic measures are inappropriate. However, their use in economic evaluation may be compromised by naming the condition; the exclusion of side effects and comorbidities; and focusing effects. Whether a reduction in comparability should be accepted depends on the extent of any gain in validity and responsiveness. This will depend on the condition and measure in question. Research agenda: (1) The appropriateness of generic preference-based measures should be examined in more conditions (and compared with CSPBMs). (2) Further quantitative and qualitative work ir requested into the impact of, and reasons for labelling effects. (3) Use of add-ons for condition-specific measures (for side effects and comorbidities) and as a solution to the limitation of generic measures should be explored. Funding: The National Institute for Health Research Health Technology Assessment programme.
Recent trends in Translation Studies advocate a focus on translation as a form of intercultural communication. Yet in some cases there seems to be a lack of awareness as regards the theoretical problems involved in every cultural approach to translation. The aim of this article is to highlight some aspects of these problems by bringing to the fore the interconnections between the question of translation and the general issue of culture. More specifically, the emphasis will be put on the interpretive dimension of translation and the peculiarities of the translator's interpretive moves within different worlds of significations. The approach outlined here draws on insights from the works of Clifford Geertz, Hans-Georg Gadamer, and Cornelius Castoriadis, and the conclusions to be reached will inevitably point to the rejection of some deep-seated metaphors about translation, such as the meaning transfer metaphor.
Children's literature is a wonderful addition to the general music classroom. Stories and poems can be key strategic tools for teaching musical concepts and skills while leading students to further experience writing, vocabulary, and literature. Children's literature and music provide an opportunity to increase the love of music and reading within students. This article considers the three phases that music educators experience as they prepare lessons to enhance and engage music learning with children's literature. Examples, strategies, and a sample lesson plan are included in this article.
We estimated the genetic variability of nine fish species from the Brazilian upper Paraná River floodplain (Astyanax altiparanae, Hoplias malabaricus, Leporinus lacustris, Loricariichthys platymetopon, Parauchenipterus galeatus, Pimelodus maculatus, Rhaphiodon vulpinus, Roeboides paranensis and Serrasalmus marginatus) based on data for 36 putative allozyme loci obtained using corn starch gel electrophoresis of 13 enzymatic systems: aspartate aminotransferase (EC 2.6.1.1), acid phosphatase (EC 3.1.3.2), esterase (EC 3.1.1.1), glycerol-3-phosphate dehydrogenase (EC 1.1.1.8), glucose-6-phosphate dehydrogenase (EC 1.1.1.49), glucose-6-phosphate isomerase (EC 5.3.1.9), Iditol dehydrogenase (EC 1.1.1.14), isocitrate dehydrogenase - NADP+ (EC 1.1.1.42), L-lactate dehydrogenase (EC 1.1.1.27), malate dehydrogenase (EC 1.1.1.37), malate dehydrogenase-NADP+ (EC 1.1.1.40), phosphoglucomutase (EC 5.4.2.2) and superoxide dismutase, (EC 1.15.1.1). The mean expected heterozygosity varied from zero to 0.147. When data from the literature for 75 species of tropical fish were added to the nine species of this study, the heterozygosity values differed significantly among the groups of different reproductive strategies. The highest mean heterozygosity was for the non-migratory without parental care, followed by the long-distance migratory, and the lowest mean was for the non-migratory with parental care or internal fecundation.