Az egészségügyi és az orvosbiológiai kutatások adatainak széttagoltsága az adatvezérelt döntéseken alapuló, személyre szabott orvoslás egyik akadálya. A fejlődéshez a méretben és komplexitásban is rendkívüli, ám töredezett egészségügyi adatkincs hatékony kiaknázását, illetve az intézményeken vagy akár határokon is átívelő adatmegosztást biztosító technológiák szükségesek. A biobankok nemcsak a minták archívumai, hanem adatintegrációs központok is egyúttal. A biobankok adatainak együttműködésben történő elemzése értékesebb következtetéseket ígér. Az adatok megosztásának előfeltétele a harmonizáció, azaz a minták egyedi klinikai és molekuláris jellemzőinek egységes adatmodellben és standard kódokkal történő leképezése. Az egészségügyben keletkezett információk ezekben a közös sémára illesztett adatbázisokban válnak elérhetővé a gépi tanulás számára, így a módszer az együttműködés során a személyes adatokat tiszteletben tartó felhasználásra is lehetőséget ad. Az érzékeny egészségügyi adatok újraértékelése elképzelhetetlen a személyes adatok védelme nélkül, amelynek jogi és koncepcionális kereteit a GDPR- (General Data Protection Regulation) és a FAIR- (findable, accessible, interoperable, reusable) elvek jelölik ki. Az Európában működő biobankok számára a BBMRI-ERIC (Biobanking and Biomolecular Research Infrastructure – European Research Infrastructure Consortium) kutatási infrastruktúra fejleszt közös irányelveket, amelyhez hazánk 2021-ben mint Magyar BBMRI Csomópont csatlakozott. Első lépésben a biobankok szövetségében kapcsolódhatnak össze a széttagolt adathalmok, ahol sokrétű kutatási cél által motivált, igényesen összerendezett adatkészletek válnak hozzáférhetővé. Ezt követően, a betegellátás valós környezetében keletkezett adatok magasabb szinten történő értékelése is lehetővé válik, így a klinikai vizsgálatok szigorú keretek között generált bizonyítékai új szintre kerülhetnek. Közleményünkben a „federált” adatmegosztásban rejlő lehetőségeket mutatjuk be a Semmelweis Egyetem biobankjainak közös projektje kapcsán. Orv Hetil. 2023; 164(21): 811–819.
International audience TraduXio is a digital environment for computer assisted multilingual translation which is web-based, free to use and with an open source code. Its originality is threefold-whereas traditional technologies are limited to two languages (source/target), TraduXio enables the comparison of different versions of the same text in various languages; its concordancer provides relevant and multilingual suggestions through a classification of the source according to the history, genre and author; it uses collaborative devices (privilege management, forums, networks, history of modification, etc.) to promote collective (and distributed) translation. TraduXio is designed to encourage the diversification of language learning and to promote a reappraisal of translation as a professional skill. It can be used in many different ways, by very diverse kind of people. In this presentation, I will present the recent developments of the software (its version 2.1) and illustrate how specific groups (language teaching, social sciences, literature) use it on a regular basis. In this paper, I present the technology but concentrate more on the possible uses of TraduXio, thus focusing on translators' feedback about their experience when working in this digital environment in a truly collaborative way.
History of scholarship and learning. The humanities, Bibliography. Library science. Information resources
TraduXio is a digital environment for computer assisted multilingual translation which is web-based, free to use and with an open source code. Its originality is threefold-whereas traditional technologies are limited to two languages (source/target), TraduXio enables the comparison of different versions of the same text in various languages; its concordancer provides relevant and multilingual suggestions through a classification of the source according to the history, genre and author; it uses collaborative devices (privilege management, forums, networks, history of modification, etc.) to promote collective (and distributed) translation. TraduXio is designed to encourage the diversification of language learning and to promote a reappraisal of translation as a professional skill. It can be used in many different ways, by very diverse kind of people. In this presentation, I will present the recent developments of the software (its version 2.1) and illustrate how specific groups (language teaching, social sciences, literature) use it on a regular basis. In this paper, I present the technology but concentrate more on the possible uses of TraduXio, thus focusing on translators' feedback about their experience when working in this digital environment in a truly collaborative way.
History of scholarship and learning. The humanities, Bibliography. Library science. Information resources
Jacky Akoka, Isabelle Comyn-Wattiau, Stéphane Lamassé
et al.
Prosopographic databases, which allow the study of social groups through their bibliography, are used today by a significant number of historians. Computerization has allowed intensive and large-scale exploitation of these databases. The modeling of these proposopographic databases has given rise to several data models. An important problem is to ensure a level of quality of the stored information. In this article , we propose a generic data model allowing to describe most of the existing prosopographic databases and to enrich them by integrating several quality concepts such as uncertainty, reliability, accuracy or completeness.
History of scholarship and learning. The humanities, Bibliography. Library science. Information resources
By reasoning about the claims and speculations promised as part of the public discourse, we analyze the hypothesis that flaws in software engineering played a critical role in the Boeing 737 MCAS incidents. We use promise-based reasoning to discuss how, from an outsider's perspective, one may assemble clues about what went wrong. Rather than looking for a Rational Alternative Design (RAD), as suggested by Wendel, we look for candidate flaws in the software process. We describe four such potential flaws. Recently, Boeing has circulated information on its envisaged MCAS algorithm upgrade. We cast this as a promise to resolve the flaws, i.e. to provide a RAD for the B737 Max. We offer an assessment of B-Max-New based on the public discourse.
Neville's algorithm is known to provide an efficient and numerically stable solution for polynomial interpolations. In this paper, an extension of this algorithm is presented which includes the derivatives of the interpolating polynomial.
The problem of optimization of a transport traffic at preliminary registration of demands with use of the CBSMAP model is investigated. For the solution of an objective application of the queueing theory and the theory of controlled processes is supposed.
Creating a photomap plays a critical role in navigation. Therefore, flying vehicles are usually used to create topdown maps of the environment. In this report we used two different aerial vehicles to create a map in a simulated environment
This paper is in related to the demand genrated by the consumer for a time for the power which is being viewed by taking some measures to solve the demand need.
We extend the AIGER format, as used in HWMCC, to a format that is suitable to define synthesis problems with safety specifications. We recap the original format and define one format for posing synthesis problems and one for solutions of synthesis problems in this setting.
This submission has been withdrawn by arXiv administrators because it contains fictitious content and was submitted under a pseudonym, which is against arXiv policy.
Regarding some papers and notes submitted to, or presented at, the second congress of the International Torah Codes Society in Jerusalem, Israel, June 2000.
Methanolothermal reaction of Cs2CO3 with Ge and Se at 190 °C yields Cs4Ge4Se10 · 2 CH3OH and Cs4Ge2Se8, the structures of which have been determined by X-ray structural analysis. The anion [Ge4Se10]4 in Cs4Ge4Se10)·2 CH3OH displays an adamantane-like structure in which four GeSe4 tetrahedra are linked via joint vertices. In contrast Cs4Ge2Se8 contains the novel dinuclear anion [Ge2Se8]4-, the first example of a selenidogermanate(IV) exhibiting Se2 bridging units. Two GeSe4 tetrahedra are linked in this anion through Se-Se bonds to yield a six-membered ring, which displays a chair conformation and crystallographic C2h symmetry.