Hasil untuk "Costs"

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S2 Open Access 2019
Antimicrobial Resistance: Implications and Costs

Porooshat Dadgostar

Abstract Antimicrobial resistance (AMR) has developed as one of the major urgent threats to public health causing serious issues to successful prevention and treatment of persistent diseases. In spite of different actions taken in recent decades to tackle this issue, the trends of global AMR demonstrate no signs of slowing down. Misusing and overusing different antibacterial agents in the health care setting as well as in the agricultural industry are considered the major reasons behind the emergence of antimicrobial resistance. In addition, the spontaneous evolution, mutation of bacteria, and passing the resistant genes through horizontal gene transfer are significant contributors to antimicrobial resistance. Many studies have demonstrated the disastrous financial consequences of AMR including extremely high healthcare costs due to an increase in hospital admissions and drug usage. The literature review, which included articles published after the year 2012, was performed using Scopus, PubMed and Google Scholar with the utilization of keyword searches. Results indicated that the multifactorial threat of antimicrobial resistance has resulted in different complex issues affecting countries across the globe. These impacts found in the sources are categorized into three different levels: patient, healthcare, and economic. Although gaps in knowledge about AMR and areas for improvement are obvious, there is not any clearly understood progress to put an end to the persistent trends of antimicrobial resistance.

1379 sitasi en Business, Medicine
S2 Open Access 2018
Economic Costs of Diabetes in the U.S. in 2017

Ping Zhang, M. Laxy, T. Hoerger et al.

OBJECTIVE This study updates previous estimates of the economic burden of diagnosed diabetes and quantifies the increased health resource use and lost productivity associated with diabetes in 2017. RESEARCH DESIGN AND METHODS We use a prevalence-based approach that combines the demographics of the U.S. population in 2017 with diabetes prevalence, epidemiological data, health care cost, and economic data into a Cost of Diabetes Model. Health resource use and associated medical costs are analyzed by age, sex, race/ethnicity, insurance coverage, medical condition, and health service category. Data sources include national surveys, Medicare standard analytical files, and one of the largest claims databases for the commercially insured population in the U.S. RESULTS The total estimated cost of diagnosed diabetes in 2017 is $327 billion, including $237 billion in direct medical costs and $90 billion in reduced productivity. For the cost categories analyzed, care for people with diagnosed diabetes accounts for 1 in 4 health care dollars in the U.S., and more than half of that expenditure is directly attributable to diabetes. People with diagnosed diabetes incur average medical expenditures of ∼$16,750 per year, of which ∼$9,600 is attributed to diabetes. People with diagnosed diabetes, on average, have medical expenditures ∼2.3 times higher than what expenditures would be in the absence of diabetes. Indirect costs include increased absenteeism ($3.3 billion) and reduced productivity while at work ($26.9 billion) for the employed population, reduced productivity for those not in the labor force ($2.3 billion), inability to work because of disease-related disability ($37.5 billion), and lost productivity due to 277,000 premature deaths attributed to diabetes ($19.9 billion). CONCLUSIONS After adjusting for inflation, economic costs of diabetes increased by 26% from 2012 to 2017 due to the increased prevalence of diabetes and the increased cost per person with diabetes. The growth in diabetes prevalence and medical costs is primarily among the population aged 65 years and older, contributing to a growing economic cost to the Medicare program. The estimates in this article highlight the substantial financial burden that diabetes imposes on society, in addition to intangible costs from pain and suffering, resources from care provided by nonpaid caregivers, and costs associated with undiagnosed diabetes.

2096 sitasi en Economics, Medicine
S2 Open Access 2021
Atlas of AI: Power, Politics and the Planetary Costs of Artificial Intelligence

Kate Crawford

ATLAS OF AI: Power, Politics, and the Planetary Costs of Artificial Intelligence by Kate Crawford. New Haven, CT: Yale University Press, 2021. 336 pages. Hardcover; $28.00. ISBN: 9780300209570. *Atlas of AI: Power, Politics, and the Planetary Costs of Artificial Intelligence is Kate Crawford's analysis of the state of the AI industry. A central idea of her book is the importance of redefining Artificial Intelligence (AI). She states, "I've argued that there is much at stake in how we define AI, what its boundaries are, and who determines them: it shapes what can be seen and contested" (p. 217). *My own definition of AI goes something like this: I imagine a future where I'm sitting in a cafe drinking coffee with my friends, but in this future, one of my friends is a robot, who like me is trying to make a living in this world. A future where humans and robots live in harmony. Crawford views this definition as mythological: "These mythologies are particularly strong in the field of artificial intelligence, where the belief that human intelligence can be formalized and reproduced by machines has been axiomatic since the mid-twentieth century" (p. 5). I do not know if my definition of artificial intelligence can come true, but I am enjoying the process of building, experimenting, and dreaming. *In her book, she asks me to consider that I may be unknowingly participating, as she states, in "a material product of colonialism, with its patterns of extraction, conflict, and environmental destruction" (p. 38). The book's subtitle illuminates the purpose of the book: specifically, the power, politics, and planetary costs of usurping artificial intelligence. Of course, this is not exactly Crawford's subtitle, and this is where I both agree and disagree with her. The book's subtitle is actually Power, Politics, and the Planetary Costs of Artificial Intelligence. In my opinion, AI is more the canary in the coal mine. We can use the canary to detect the poisonous gases, but we cannot blame the canary for the poisonous gas. It risks missing the point. Is AI itself to be feared? Should we no longer teach or learn AI? Or is this more about how we discern responsible use and direction for AI technology? *There is another author who speaks to similar issues. In Weapons of Math Destruction, Cathy O'Neil states it this way, "If we had been clear-headed, we all would have taken a step back at this point to figure out how math had been misused ... But instead ... new mathematical techniques were hotter than ever ... A computer program could speed through thousands of resumes or loan applications in a second or two and sort them into neat lists, with the most promising candidates on top" (p. 13). *Both Crawford and O'Neil point to human flaws that often lead to well-intentioned software developers creating code that results in unfair and discriminatory decisions. AI models encode unintended human biases that may not evaluate candidates as fairly as we would expect, yet there is a widespread notion that we can trust the algorithm. For example, the last time you registered an account on a website, did you click the checkbox confirming that "yes, I read the disclaimer" even though you did not? When we click "yes" we are accepting this disclaimer and placing trust in the software. Business owners place trust in software when they use it to make predictions. Engineers place trust in their algorithms when they write software without rigorous testing protocols. I am just as guilty. *Crawford suggests that AI is often used in ways that are harmful. In the Atlas of AI we are given a tour of how technology is damaging our world: strip mining, labor injustice, the misuse of personal data, issues of state and power, to name a few of the concerns Crawford raises. The reality is that AI is built upon existing infrastructure. For example, Facebook, Instagram, YouTube, Amazon, TikTok have been collecting our information for profit even before AI became important to them. The data centers, CPU houses, and worldwide network infrastructure were already in place to meet consumer demand and geopolitics. But it is true that AI brings new technologies to the table, such as automated face recognition and decision tools to compare prospective employment applicants with diverse databases and employee monitoring tools that can make automatic recommendations. Governments, militaries, and intelligence agencies have taken notice. As invasion of privacy and social justice concerns emerge, Crawford calls us to consider these issues carefully. *Reading Crawford's words pricked my conscience, convicting me to reconsider my erroneous ways. For big tech to exist, to supply what we demand, it needs resources. She walks us through the many resources the technology industry needs to provide what we want, and AI is the "new kid on the block." This book is not about AI, per se; it is instead about the side effects of poor business/research practices, opportunist behavior, power politics, and how these behaviors not only exploit our planet but also unjustly affect marginalized people. The AI industry is simply a new example of this reality: data mining, low wages to lower costs, foreign workers with fewer rights, strip mining, relying on coal and oil for electricity (although some tech companies have made strides to improve sustainability). This sounds more like a parable about the sins of the tech industry than a critique about the dangers of AI. *Could the machine learning community, like the inventors of dynamite who wanted to simply help railroads excavate tunnels, be unintentionally causing harm? Should we, as a community, be on the lookout for these potential harms? Do we have a moral responsibility? Maybe the technology sector needs to look more inwardly to ensure that process efficiency and cost savings are not elevated as most important. *I did not agree with everything that Crawford classified as AI, but I do agree that as a community we are responsible for our actions. If there are injustices, then this should be important to us. In particular, as people of faith, we should heed the call of Micah 6:8 to act justly in this world, and this includes how we use AI. *Reviewed by Joseph Vybihal, Professor of Computer Science, McGill University, Montreal, PQ H3A 0G4.

849 sitasi en Computer Science
S2 Open Access 2023
Economic Costs of Diabetes in the U.S. in 2022.

Emily D Parker, Janice Lin, T. Mahoney et al.

OBJECTIVE This study updates previous estimates of the economic burden of diagnosed diabetes, with calculation of the health resource use and indirect costs attributable to diabetes in 2022. RESEARCH DESIGN AND METHODS We combine the demographics of the U.S. population in 2022 with diabetes prevalence, from national survey data, epidemiological data, health care cost data, and economic data, into a Cost of Diabetes Economic Model to estimate the economic burden at the population and per capita levels. Health resource use and associated medical costs are analyzed by age, sex, race/ethnicity, comorbid condition, and health service category. Data sources include national surveys (2015-2020 or most recent available), Medicare standard analytic files (2020), and administrative claims data from 2018 to 2021 for a large commercially insured population in the U.S. RESULTS The total estimated cost of diagnosed diabetes in the U.S. in 2022 is $412.9 billion, including $306.6 billion in direct medical costs and $106.3 billion in indirect costs attributable to diabetes. For cost categories analyzed, care for people diagnosed with diabetes accounts for 1 in 4 health care dollars in the U.S., 61% of which are attributable to diabetes. On average people with diabetes incur annual medical expenditures of $19,736, of which approximately $12,022 is attributable to diabetes. People diagnosed with diabetes, on average, have medical expenditures 2.6 times higher than what would be expected without diabetes. Glucose-lowering medications and diabetes supplies account for ∼17% of the total direct medical costs attributable to diabetes. Major contributors to indirect costs are reduced employment due to disability ($28.3 billion), presenteeism ($35.8 billion), and lost productivity due to 338,526 premature deaths ($32.4 billion). CONCLUSIONS The inflation-adjusted direct medical costs of diabetes are estimated to rise 7% from 2017 and 35% from 2012 calculations (stated in 2022 dollars). Following decades of steadily increasing prevalence of diabetes, the overall estimated prevalence in 2022 remains relatively stable in comparison to 2017. However, the absolute number of people with diabetes has grown and contributes to increased health care expenditures, particularly per capita spending on inpatient hospital stays and prescription medications. The enormous economic toll of diabetes continues to burden society through direct medical and indirect costs.

543 sitasi en Medicine
S2 Open Access 1997
Industry costs of equity

E. Fama, K. French

Abstract Estimates of the cost of equity for industries are imprecise. Standard errors of more than 3.0% per year are typical for both the CAPM and the three-factor model of Fama and French (1993). These large standard errors are the result of(i) uncertainty about true factor risk premiums and (ii) imp ecise estimates of the loadings of industries on the risk factors. Estimates of the cost of equity for firms and projects are surely even less precise.

5679 sitasi en Economics
S2 Open Access 2023
The global costs of extreme weather that are attributable to climate change

R. Newman, Ilan Noy

Extreme weather events lead to significant adverse societal costs. Extreme Event Attribution (EEA), a methodology that examines how anthropogenic greenhouse gas emissions had changed the occurrence of specific extreme weather events, allows us to quantify the climate change-induced component of these costs. We collect data from all available EEA studies, combine these with data on the socio-economic costs of these events and extrapolate for missing data to arrive at an estimate of the global costs of extreme weather attributable to climate change in the last twenty years. We find that US\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\$$$\end{document}$ 143 billion per year of the costs of extreme events is attributable to climatic change. The majority (63%), of this is due to human loss of life. Our results suggest that the frequently cited estimates of the economic costs of climate change arrived at by using Integrated Assessment Models may be substantially underestimated.

382 sitasi en Medicine
S2 Open Access 2023
The worldwide costs of dementia in 2019

A. Wimo, Katrin M. Seeher, Rodrigo Cataldi et al.

Dementia is a leading cause of death and disability globally. Estimating total societal costs demonstrates the wide impact of dementia and its main direct and indirect economic components.

367 sitasi en Medicine

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