Hasil untuk "Mental healing"

Subba Reddy Oota, Vijay Rowtula, Shahid Mohammed et al.

Hospitalization of patients is one of the major factors for high wound care costs. Most patients do not acquire a wound which needs immediate hospitalization. However, due to factors such as delay in treatment, patient's non-compliance or existing co-morbid conditions, an injury can deteriorate and ultimately lead to patient hospitalization. In this paper, we propose a deep multi-modal method to predict the patient's risk of hospitalization. Our goal is to predict the risk confidently by collectively using the wound variables and wound images of the patient. Existing works in this domain have mainly focused on healing trajectories based on distinct wound types. We developed a transfer learning-based wound assessment solution, which can predict both wound variables from wound images and their healing trajectories, which is our primary contribution. We argue that the development of a novel model can help in early detection of the complexities in the wound, which might affect the healing process and also reduce the time spent by a clinician to diagnose the wound.

Yuxin Zhang, Fan Zhang, Zihao Song et al.

This study develops sustainable materials using hydrogel as the matrix and explores the transition from sustainable materials to user-centered sustainability, with a particular focus on achieving art healing through material experience. The findings reveal that "Aesthetic" property exert the greatest influence on art healing in the context of multimodal material experiences involving visual, tactile, and smell, followed by "Intrinsic" property, whereas "Physical" property have a comparatively limited effect. Furthermore, the study proposes a material experience framework that enables designers to systematically and holistically understanding material characteristics. It highlights the importance of considering users' psychological perceptions and emotional needs in the material design process.

J. Ball, I. Darby

Abstract Mental health disorders, particularly depression and anxiety, affect a significant number of the global population. Several pathophysiological pathways for these disorders have been identified, including the hypothalamic‐pituitary‐adrenal axis, autonomic nervous system, and the immune system. In addition, life events, environmental factors, and lifestyle affect the onset, progression, and recurrence of mental health disorders. These may all overlap with periodontal and/or peri‐implant disease. Mental health disorders are associated with more severe periodontal disease and, in some cases, poorer healing outcomes to nonsurgical periodontal therapy. They can result in behavior modification, such as poor oral hygiene practices, tobacco smoking, and alcohol abuse, which are also risk factors for periodontal disease and, therefore, may have a contributory effect. Stress has immunomodulatory effects regulating immune cell numbers and function, as well as proinflammatory cytokine production. Stress markers such as cortisol and catecholamines may modulate periodontal bacterial growth and the expression of virulence factors. Stress and some mental health disorders are accompanied by a low‐grade chronic inflammation that may be involved in their relationship with periodontal disease and vice versa. Although the gut microbiome interacting with the central nervous system (gut‐brain axis) is thought to play a significant role in mental illness, less is understood about the role of the oral microbiome. The evidence for mental health disorders on implant outcomes is lacking, but may mainly be through behaviourial changes. Through lack of compliance withoral hygiene and maintenance visits, peri‐implant health can be affected. Increased smoking and risk of periodontal disease may also affect implant outcomes. Selective serotonin reuptake inhibitors have been linked with higher implant failure. They have an anabolic effect on bone, reducing turnover, which could account for the increased loss.

Yafei Wang, Zhanfeng Li, Xingmei Chen et al.

Guided by experiments contrasting electrically accelerated recovery with natural healing, this study formulates a model to investigate the importance of electroactive differential growth and morphological changes in tissue repair. It underscores the clinical potential of leveraging electroactive differential growth for improved healing outcomes. The study reveals that voltage stimulation significantly enhances the healing and growth of biological tissues, accelerating the regeneration process across various growth modalities and steering towards isotropic growth conditions that do not favor any specific growth pathways. Enhancing the electroelastic coupling parameters improves the efficacy of bioelectric devices, initiating contraction and fortification of biological tissues in alignment with the electric field. This process facilitates swift cell migration and proliferation, as well as oriented growth of tissue. In instances of strain stiffening at elevated strains, the extreme critical growth ratio aligns with the predictions of neo-Hookean models. Conversely, for tissues experiencing strain stiffening under moderate to very low strain conditions, the strain stiffening effect substantially delays the onset of electroelastic growth instability, ultimately producing a smooth, hyperelastic surface devoid of any unstable morphologies. Our investigation, grounded in nonlinear electroelastic field and perturbation theories, explores how electric fields influence differential growth and instability in biological tissues. We examine the interactions among dimensionless voltage, internal pressure, electroelastic coupling, radius ratio, and strain stiffening, revealing their effects on promoting growth and delaying instability. This framework offers insights into the mechanisms behind electroactive growth and its instabilities, contributing valuable knowledge to the tissue healing.

Man Shen, Taiki Inoue, Mengyue Wang et al.

Defects in single-walled carbon nanotubes (SWCNTs) degrade their mechanical,electrical, and thermal properties, limiting their potential applications. To realize the diverse applications of SWCNTs, it is essential to enhance their crystallinity through effective defect healing. However, traditional thermal treatments typically require temperatures above 1800°C, which can alter the nanotube structure. Previously, defect healing of SWCNTs was achieved at a relatively low temperature of 1100°C, using C$_{2}$H$_{2}$ assistance, but the efficiency was limited. In this study, we developed a C$_{2}$H$_{2}$-assisted multiple-cycle process at an even lower temperature of 1000°C combined with air exposure, achieving highly efficient defect healing while preserving the nanotube structure. The combination of multiple-cycle treatment and air exposure between cycles was found to promote defect activation, suppress the formation of amorphous carbon, and enhance the effectiveness of defect healing. Additionally, we successfully healed commercially available bulk-scale SWCNTs (super-growth SWCNTs), noting that their healing behavior differed from lab-grown SWCNTs with smaller diameters synthesized from nanodiamond. The efficient and structure-preserved healing process developed in this study broadens the potential applications of high-quality SWCNTs, including flexible electronics, high-performance composites, and energy storage devices.

Alinafe Maenje, Joseph Malinzi

This study presents a mathematical model formulated as a system of first-order non-linear ordinary differential equations, aimed at examining the effects of different factors, classified as local and systemic factors on a wound healing process. Specifically, the model incorporates pathogens, inflammatory cells, fibroblast cells, collagen, and the initial wound size. The variables utilized in the model lack specific units since they represent combined responses of different cell types. As such, these variables serve as indicators of the relative behaviors of these cellular populations. The feasibility of the model solution is examined through the demonstration of its positivity. A threshold, denoted $R_w$, is established to determine the conditions necessary for the existence of a wound-free equilibrium. Sensitivity analysis is carried out to determine the contribution of parameters to the behavior of fibroblast cells and $R_w$, which are crucial to the wound healing process. Through numerical simulations, it is demonstrated that factors such as oxygen levels, pathogen activity, inflammatory cell activity, age, smoking, alcoholism, and stress exert considerable influence on the behaviors of these cells, thereby contributing to delayed wound healing and the occurrence of chronic wounds.

Tejmani Behera, Boris Louis, Lukas Paesen et al.

The stability and performance of halide perovskite photovoltaic devices are critically limited by progressive defect generation and associated local non-radiative losses during operation. Self-healing of defects provides a promising pathway to prolong device functionality, yet the underlying microscopic mechanisms remain poorly understood, particularly the role of interfacial chemistry on trap dynamics and healing kinetics. Here, we elucidate self-healing and defect evolution in triple-cation mixed halide (TCMH) perovskite films and their device-relevant charge transport layer heterostructures subjected to photo-induced damage. Using correlation clustering imaging (CLIM), our recently developed local functional imaging tool, we map spatiotemporal photoluminescence heterogeneity to track defect dynamics in pristine and heterostructure films. The defect healing follows bi-phasic kinetics, with an initial electronic relaxation (tens of minutes) and a subsequent slower phase (~ hours) associated to ionic and lattice rearrangement. Most importantly, our results demonstrate that the chemical nature of charge-transport layers modulates trap activity, healing kinetics, and halide redistribution, with heterostructures exhibiting faster recovery than pristine films, a boon for device resilience. These findings provide new insights into the dynamic interaction between defects, interfaces, and ion migration, and establish a framework for rational design of durable, next-generation perovskite optoelectronic devices.

Laura Caci, Emanuela Nyantakyi, Kathrin Blum et al.

Background Organizational readiness for change (ORC), referring to psychological and behavioral preparedness of organizational members for implementation, is often cited in healthcare implementation research. However, evidence about whether and under which conditions ORC is relevant for positive implementation results remains ambiguous, with past studies building on various theories and assessing ORC with different measures. To strengthen the ORC knowledge base, we therefore identified factors investigated in the empirical literature alongside ORC, or as mediators and/or moderators of ORC and implementation. Method We conducted a systematic review of experimental, observational, and hybrid studies in physical, mental, and public health care that included a quantitative assessment of ORC and at least one other factor (e.g., ORC correlate, predictor, moderator, or mediator). Studies were identified searching five online databases and bibliographies of included studies, employing dual abstract and full text screening. The study synthesis was guided by the Consolidated Framework for Implementation Research integrated with the Theory of ORC. Study quality was appraised using the Mixed Methods Appraisal Tool. Results Of 2,907 identified studies, 47 met inclusion criteria, investigating a broad range of factors alongside ORC, particularly contextual factors related to individuals and the innovation. Various ORC measures, both home-grown or theory-informed, were used, confirming a lack of conceptual clarity surrounding ORC. In most studies, ORC was measured only once. Conclusions This systematic review highlights the broad range of factors investigated in relation to ORC, suggesting that such investigation may enhance interpretation of implementation results. However, the observed diversity in ORC conceptualization and measurement supports previous calls for clearer conceptual definitions of ORC. Future efforts should integrate team-level perspectives, recognizing ORC as both an individual and team attribute. Prioritizing the use of rigorous, repeated ORC measures in longitudinal implementation research is essential for advancing the collective ORC knowledge base.

Worinthep Chuasamran, Jintana Jandeem, Sorsuangsuda Pongkaew

The objective of this research was to evaluate the effectiveness of the “Smart Love, Smart Parenting” Program in enhancing parenting skills and multiple intelligence in school-aged children in Nan Province. The study was based on the concept of positive parenting. A quasi-experimental research design was employed, using a pre-post single group design. The sample consisted of 70 households with children aged 6–12 years from general areas and 153 households from remote areas. Data were collected from parents before and after participating in the program using a parenting skills assessment and a multiple intelligence assessment for children. The findings revealed statistically significant improvements in both parenting skills (p < 0.01) and children’s multiple intelligence (p < 0.05) after program participation. The “Smart Love, Smart Parenting” Program was well received by parents, teachers, and public health personnel, who recognized the importance of strengthening family relationships and community support in child development. The findings indicate that the “Smart Love, Smart Parenting” Program is effective in promoting parenting skills and enhancing the multiple intelligence of school-aged children in both general and remote areas. The findings have implications for strengthening and developing parenting training programs within communities, particularly in areas with limited access to public health services. Moreover, the results can be applied in designing programs that foster positive relationships among homes, schools, and communities to sustainably support the development of parenting skills and children’s multiple intelligence.

Emma Gendre, Andrea Soubelet, Charlotte Henson et al.

Background: Posttraumatic growth (PTG) is associated with two important cognitive factors: challenge to core beliefs and event-related rumination. The objectives of this study were to 1) validate the French versions of the Core Beliefs Inventory (CBI, Cann et al., 2010) and the Event-Related Rumination Inventory (ERRI, Cann et al., 2011) and 2) explore direct and indirect effects of core beliefs and rumination on PTG in the long-term. Methods: A sample of adults (N = 433 at T1, N = 222 at T2, six months later) who had experienced at least one traumatic event in their lifetime completed online questionnaires measuring core beliefs, rumination, distress, and PTG. Confirmatory factor analyses, correlations, and structural equation modeling were performed. Results: Analyses supported a two-factor structure for the CBI: (1) beliefs about justice, control, and the causality of events and (2) beliefs about relationships, self, and the future; as well as for the ERRI: (1) intrusive rumination and (2) deliberate rumination. Both scales showed good psychometric qualities. Disruption of beliefs about relationships, self, and the future at T1 and deliberate rumination at T2 had a direct positive effect on PTG at T2, while intrusive rumination at T1 had no effect. Deliberate rumination mediated both the relationship between disruption of core beliefs and PTG and the relationship between intrusive rumination and PTG. Conclusions: The results demonstrate the validity of the CBI and ERRI and are consistent with the theoretical model emphasizing the importance of cognitive processing in the development of PTG.

C. Basch, L. Donelle, J. Fera et al.

Background Social media platforms that are based on the creation of visual media, such as TikTok, are increasingly popular with adolescents. Online social media networks provide valuable opportunities to connect with each other to share experiences and strategies for health and wellness. Objective The aim of this study was to describe the content of the hashtag #mentalhealth on TikTok. Methods This cross-sectional, descriptive content analysis study included 100 videos with the hashtag #mentalhealth on TikTok. All videos that included the hashtag #mentalhealth were analyzed and coded for the presence of content categories. Additionally, the comments to each video were viewed and coded for content in the following themes: offering support or validation; mentioning experience with suicide or suicidal ideation; mentioning experience with self-harm; describing an experience with hospitalization for mental health issues; describing other mental health issues; and sharing coping strategies, experiences of healing, or ways to feel better. Results Collectively, the 100 videos studied received 1,354,100,000 views; 266,900,000 likes; and 2,515,954 comments. On average, each video received 13,406,930.69 (SD 8,728,095.52) views; 2,657,425.74 (SD 1,449,920.45) likes; and 24,910.44 (SD 21,035.06) comments. The only content category observed in most (51/100, 51%) of the videos included in the sample was “general mental health.” The remaining content categories appeared in less than 50% of the sample. In total, 32% (32/100) of the videos sampled received more than the overall average number of likes (ie, more that 2.67 million likes). Among these 32 videos, 23 (72%) included comments offering support or validation and 20 (62%) included comments that described other mental health issues or struggles. Conclusions With over 1 billion cumulative views, almost half of the assessed TikTok videos included in this study reported or expressed symptoms of mental distress. Future research should focus on the potential role of intervention by health care professionals on social media.

Wenyu Li, Yinuo Zhu, Xin Lin et al.

Traditional discriminative approaches in mental health analysis are known for their strong capacity but lack interpretability and demand large-scale annotated data. The generative approaches, such as those based on large language models (LLMs), have the potential to get rid of heavy annotations and provide explanations but their capabilities still fall short compared to discriminative approaches, and their explanations may be unreliable due to the fact that the generation of explanation is a black-box process. Inspired by the psychological assessment practice of using scales to evaluate mental states, our method which is called Mental Analysis by Incorporating Mental Scales (MAIMS), incorporates two procedures via LLMs. First, the patient completes mental scales, and second, the psychologist interprets the collected information from the mental scales and makes informed decisions. Experimental results show that MAIMS outperforms other zero-shot methods. MAIMS can generate more rigorous explanation based on the outputs of mental scales

Hannah R. Lawrence, Renee A. Schneider, Susan B. Rubin et al.

Global rates of mental health concerns are rising, and there is increasing realization that existing models of mental health care will not adequately expand to meet the demand. With the emergence of large language models (LLMs) has come great optimism regarding their promise to create novel, large-scale solutions to support mental health. Despite their nascence, LLMs have already been applied to mental health related tasks. In this paper, we summarize the extant literature on efforts to use LLMs to provide mental health education, assessment, and intervention and highlight key opportunities for positive impact in each area. We then highlight risks associated with LLMs' application to mental health and encourage the adoption of strategies to mitigate these risks. The urgent need for mental health support must be balanced with responsible development, testing, and deployment of mental health LLMs. It is especially critical to ensure that mental health LLMs are fine-tuned for mental health, enhance mental health equity, and adhere to ethical standards and that people, including those with lived experience with mental health concerns, are involved in all stages from development through deployment. Prioritizing these efforts will minimize potential harms to mental health and maximize the likelihood that LLMs will positively impact mental health globally.

Philippe Rauffet, Sorin Moga, Alexandre Kostenko

This study examines the relationship between mental workload and the cognitive control implemented in multitasking activity. A MATB-II experiment was conducted to simulate different conditions of multitasking demand, and to collect the behavioral and physiological activities of 17 participants. The results show that implementation of different modes of cognitive control can be detected with physiological indicators, and that cognitive control could be seen as a moderator of the effect of mental stress (task demand) upon mental strain (physiological responses).

Robert W. Emmerton, Christina Camilleri, Stephen Sammut

Background: Scientific literature indicates a continued global decline in mental health, including among university students, with continued efforts to comprehend potential contributors. Our cross-sectional study sought to build upon our previous work and investigate the current dynamic of mental health and potential stressors reported among a sample of university students, as well as potential similarities/differences to previous years. Methods: University students (n = 820 participants who met inclusion criteria; aged 18+) were administered an anonymous survey consisting of questions assessing: (1) demographics, (2) mental health (depression, anxiety, stress), and (3) potential stressors. Results: Our results indicate a significant proportion of students reporting severe and extremely severe levels of depression, anxiety and stress, with a substantial increase in severe and extremely severe levels relative to previous years. Similar to our previous work, academic performance, pressure to succeed and quality of sleep were among the top stressors reported. Significant predictors of mental health included pressure to succeed, self-esteem, body image and relationship with friends and family. Limitations: A key limitation of this study includes its cross-sectional, rather than longitudinal, design. Conclusions: The university student population appears to be experiencing a continued shift towards worse mental health. In addition to the traditional college-related sources of stress, consideration is also necessary of the impact of non-college-specific stressors that could linger beyond the individual's time in college. This approach, along with consideration of the deeper underlying contributors to such stressors, may potentially assist in more appropriately, proactively, and successfully addressing the global mental health pandemic.

Jiaheng Liang, Longlong Cui, Jiankang Li et al.

Skin injury is a major problem threatening human physical and mental health, and how to promote wound healing has been the focus. Developing new wound dressings is an important strategy in skin regeneration. Aloe vera is a medicinal plant with a long history, complex constituents, and various pharmacological activities. Many studies have shown that A. vera plays an important role in promoting wound healing. Adding A. vera to wound dressing has become an ideal way. This review will describe the process of skin injury and wound healing and analyze the role of A. vera in wound healing. In addition, the types of wound dressing and the applications of A. vera in wound dressing will be discussed. Impact statement Skin damage has become a clinical problem, which not only affects the body and mind of patients but also causes great loss to the society and economy. Wound healing is the key to repair of skin damage, and the application of wound dressing can effectively improve wound healing. Aloe vera, as an ancient medicinal plant, has attracted the attention of researchers because of its remarkable effect on wound healing. This review article provides readers with the process of wound healing, the effect of A. vera in wound healing, and the application of A. vera in various wound dressing, hoping to bring inspiration to skin damage repair.

Ao Sun, D. Hu, Xinye He et al.

Burn wound infections cause serious problems for public health. More than 180,000 patients die from burns every year worldwide. In addition, the difficulty of healing wounds and wound infections caused by burns affects the mental health of patients. Therefore, it is very important to develop a wound dressing that can promote wound repair and exhibits good antibacterial effects. Here, we used oxidized konjac glucomannan (OKGM), γ-poly(glutamic acid) modified with dopamine and L -cysteine (γ-PGA-DA-Cys) and ε-polylysine (ε-PL) to produce an OKGM/γ-PGA-DA-Cys/ε-PL (OKPP) hydrogel. This hydrogel was produced by thiol-aldehyde addition and Schiff-base reactions and has the ability to be injected and self-heal. The results showed that the hydrogel exhibits good antibacterial effects on Pseudomonas aeruginosa and Staphylococcus aureus and has antioxidant effects in vitro. Moreover, the hydrogel also exhibits good adhesion. In a burn wound infection model, the hydrogel promoted wound healing and reduced the production of inflammation. These results proved that the hydrogel has clinical potential as a wound dressing for burn wound infection. In this study, we prepared OKPP hydrogel constructed from, OKGM, ε-PL, and γ-PGA modified by dopamine and l -cysteine. OKPP hydrogel has the ability of injectable and self-healing through the thiol-aldehyde addition and schiff-base reactions, which can solve the problem of long time use and gel breaking. OKPP hydrogel has antioxidant properties and can scavenge free radicals. This hydrogel has good antibacterial effect on Pseudomonas aeruginosa and Staphylococcus aureus , and also has strong adhesion. In the burn wound infection model, OKPP hydrogel can promote wound healing and reduce the production of inflammatory factors. It is proved that this hydrogel has good clinical potential as a wound dressing for burn wound infection.

L. Xue, Tewei Deng, R. Guo et al.

Chronic wounds are a major health problem with increasing global prevalence, which endangers the physical and mental health of those affected and is a heavy burden to healthcare providers. Artemisia argyi extract (AE) has excellent antibacterial and anti-inflammatory properties. In this research, we developed AE loaded composite hydrogel scaffold based on methacrylate gelatin (GelMA)/methacrylate hyaluronic acid (HAMA) and mesoporous silica nanoparticle (MSN) as sustained-release drug carrier vehicles for the treatment of chronic wounds. The presented GelMA/1%HAMA hydrogel possessed stable rheological properties, suitable mechanical properties, appropriate biodegradability, swelling, sustained-release AE capacity. In vitro antibacterial and cell experiments showed that the GelMA/HAMA/MSN@AE hydrogel had excellent antibacterial activity and biocompatibility and induced macrophages to differentiate into M2 phenotype. In vivo wound healing of rat full-thickness cutaneous wounds further demonstrated that the prepared GelMA/HAMA/MSN@AE hydrogel could significantly promote chronic wound healing by upregulating the expression of IL-4, TGF-β1, CD31, and α-SMA but downregulating the expression of TNF-α and IFN-γ and promoting M1-M2 macrophages polarization. Altogether, we believe that the GelMA/HAMA/MSN@AE hydrogel will have wide application prospects in healing chronic wounds.

K. Matthews, I. Morgan, Kelly Davis et al.

Structural racism causes significant inequities in the diagnosis of perinatal and maternal mental health disorders and access to perinatal and maternal mental health treatment. Black birthing populations are particularly burdened by disjointed systems of care for mental health. To identify strategies to address racism and inequities in maternal and infant mental health care, we interviewed ten Black women who support Black birthing people, including mental health practitioners, researchers, and activists, in February 2021. The five key pathways to address racism and inequities that we identified from the stakeholder interviews are educating and training practitioners; investing in the Black women mental health workforce; investing in Black women-led community-based organizations; valuing, honoring, and investing in community and traditional healing practices; and promoting integrated care and shared decision making. These pathways highlight critical resources needed to improve the quality of maternal mental health care for Black birthing populations.

Garson Leder, Tadeusz Zawidzki

This paper presents a naturalist skill-based alternative to traditional function-based naturalist theories of mental health and disorder. According to the novel skill view outlined here, mental health is a skilled action of individuals, rather than a question of the functioning of mental mechanisms. Mental disorder is the failure or breakdown of this skill. This skill view of mental health is motivated by focusing on the process of mental healing. This paper argues that, when we start with a focus on how and why individuals heal from mental disorders, we gain a better understanding of what mental health is: the exercise of self-regulatory metacognitive skill.