Nino Adib Chifdillah, Adinda Gusti Nurhaliza, Yona Palin
et al.
Oral health is a global health issue among children. The study aimed to analyze the effect of health education using crossword puzzles on knowledge about oral health among students at SDN 006 Loa Janan Ilir. The study was a pre-experimental study using an one-group pretest-posttest design. The intervention involved health education using crossword puzzles as a medium. The sample consisted of 79 fifth-grade students selected through total sampling. Data were collected through questionnaires and analyzed statistically using the Wilcoxon test. The validity of the questionnaire was tested by comparing the calculated r-value with the table r-value. The questionnaire validity test used Cronbach's Alpha value. The research results showed that most respondents were 11 years old (63 students, 79.7%), female (45 students, 57%), had parents with a secondary education level (40 students, 50.6%), and had never received information about KGM (64 students, 81%). The number of students with good knowledge increased by 56 (80.9%). Meanwhile, the number of students with adequate knowledge decreased by 44, and the number of students with insufficient knowledge decreased by 12. Statistical analysis results indicated that there was an effect of the intervention on respondents' knowledge (ρ-value=0.000). Crossword puzzles was effective as a health education media about oral health for elementary school students.
Premenstrual Syndrome (PMS) is a collection of physical and emotional symptoms occurring prior to menstruation that can disrupt daily activities. Dietary patterns and nutritional status are known to influence PMS symptoms. This study aims to analyze the relationship between dietary intake (energy, carbohydrates, protein, fat, magnesium, and vitamin B6) and nutritional status (based on Body Mass Index/BMI) with the incidence of PMS among female students from both health and non-health study programs at Universitas Airlangga. This research employed an analytical observational study with a cross-sectional design. A total of 103 female students from the 4th semester of the Nutrition and Islamic Economics study programs were selected through proportional random sampling. Data were collected using questionnaires on respondent characteristics, a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), anthropometric measurements, and the Shortened Premenstrual Assessment Form (SPAF). Data analysis was performed descriptively and inferentially using Spearman's rank correlation test. The results showed a significant relationship between energy intake (p = 0.002) and fat intake (p = 0.001) with PMS. No significant relationship was found for carbohydrate, protein, magnesium, and vitamin B6 intake (p > 0.05). Additionally, nutritional status based on BMI was significantly associated with PMS (p = 0.001), indicating that both underweight and overweight students were more likely to experience PMS. These findings highlight that imbalanced energy and fat intake, as well as abnormal nutritional status, may be contributing factors to PMS. Therefore, increasing awareness of proper nutrition and reproductive health is essential to reduce PMS symptoms among female students.
Halfie Zaqiyah Gusti Puspitasari, Sihqina Ramadhani Selwis Raistanti, Salsabila Fiqrotu Tsauroh
et al.
Background: Several factors such as high job demands, unsupportive health care environment, and low salary contribute to burnout among maternity nurses and midwives. Untreated burnout can have a negative impact on the quality of care, the mental health of midwifery nurses and midwives, and therefore patient well-being.
Objective: To identify risk factors for burnout among maternity nurses and midwives.
Method: This study was a scoping review in accordance with Updated Methodological Guidance for The Conduct of Scoping Reviews 2020. Articles were obtained from three electronic data sources, namely PubMed, ScienceDirect, and Wiley. Inclusion criteria included English-language article, published between 2020 and 2024, and original research articles on burnout among maternity nurses and midwives. Articles that did not meet the criterion, such as focusing on maternity nurses and midwives in education context, were excluded. Article selection followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Review (PRISMA-ScR) Guidelines 2020 and quality assessment used the Joanna Briggs Institute (JBI) Critical Appraisal Checklist 2020 and Mixed Methods Appraisal Tool (MMAT) 2018.
Results: A total of 32.803 articles were found in the search. After screening, eight articles that met the criteria were selected and analyzed further. Based on the analysis results, it was found that the identified risk factors causing burnout in maternity nurses and midwives included socioeconomic status, work experience and duration, unpleasant experiences, job demands, and commitment.
Conclusion: Socioeconomic status, work experience and duration, unpleasant experiences, job demands, and commitment contribute to burnout among maternity nurses and midwives. Therefore, further research is needed to develop burnout prevention strategies to improve the well-being of maternity nurses and midwives.
INTISARILatar belakang: Tuntutan pekerjaan yang tinggi, lingkungan fasilitas kesehatan yang kurang mendukung, hingga gaji yang rendah, menjadi beberapa faktor pemicu burnout pada perawat maternitas. Burnout yang tidak ditangani dapat berdampak negatif pada kualitas pelayanan, kesehatan mental perawat maternitas dan bidan, serta kesejahteraan pasien.
Tujuan: Mengidentifikasi faktor risiko burnout pada perawat maternitas dan bidan.
Metode: Penelitian ini merupakan tinjauan cakupan sesuai dengan pedoman Updated Methodological Guidance for The Conduct of Scoping Reviews tahun 2020. Artikel diperoleh dari tiga sumber data elektronik, yaitu PubMed, ScienceDirect, dan Wiley. Kriteria inklusi mencakup artikel berbahasa Inggris yang diterbitkan antara 2020–2024 dan merupakan artikel penelitian orisinal tentang burnout pada perawat maternitas. Artikel yang tidak memenuhi kriteria, yakni berfokus pada perawat atau bidan dalam konteks pendidikan, telah dikeluarkan. Seleksi artikel mengikuti pedoman Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Review (PRISMA-ScR) tahun 2020 serta penilaian kualitas menggunakan Joanna Briggs Institute (JBI) Critical Appraisal Checklist tahun 2020 dan Mixed Methods Appraisal Tool (MMAT) tahun 2018.
Hasil: Sebanyak 32.803 artikel ditemukan dalam penelusuran. Setelah dilakukan skrining, didapatkan 8 artikel yang memenuhi kriteria untuk dianalisis lebih lanjut. Berdasarkan hasil analisis, didapatkan bahwa faktor risiko yang teridentifikasi menyebabkan burnout pada perawat maternitas dan bidan di antaranya adalah status sosial demografi, pengalaman dan waktu kerja, pengalaman tidak menyenangkan, tuntutan pekerjaan, dan komitmen.
Simpulan: Status sosial demografi, pengalaman dan waktu kerja, pengalaman tidak menyenangkan, tuntutan pekerjaan, dan komitmen, dapat berkontribusi menyebabkan burnout. Oleh karena itu, penelitian lebih lanjut diperlukan untuk mengembangkan strategi pencegahan burnout dalam rangka meningkatkan kesejahteraan kerja pada perawat maternitas dan bidan.
Latar Belakang: Kalsium merupakan nutrisi penting yang berperan dalam sistem biologis manusia, terutama tulang. Hasil penelitian di Benin menunjukkan asupan kalsium ibu hamil rendah, dan Kinshella melaporkan asupan kalsium ibu hamil berpenghasilan rendah sangat kurang. Di Indonesia asupan kalsium ibu hamil sebesar 403,5±343,1 mg/hari dari yang seharusnya 1200 mg/hari. Sumber kalsium adalah susu dan produk olahannya.
Tujuan: Penelitian ini bertujuan untuk mendapatkan tulang ikan yang kaya akan kalsium dan dapat menjadi alternatif sumber kalsium selain susu dan dengan harga yang lebih murah diperoleh dari limbah pengolahan ikan.
Metode: Penelitian ini dilakukan dengan dua metode eksperimen laboratorium. Sampel tulang ikan adalah kerangka ikan hasil limbah pengolahan ikan. Metode pertama tulang ikan dipresto selama 2 jam dan dikeringkan dalam pengering kabinet selama 20 jam pada suhu 60°C Sedangkan pada metode kedua, tulang ikan direndam menggunakan asam cuka sebanyak 30 ml per kg selama 10 menit. Selanjutnya, dikeringkan dalam pengering kabinet selama 4 jam pada suhu 60°C. Kadar proksimat dan kalsium tepung tulang ikan dengan dua metode tersebut diuji.
Hasil: Kadar air kedua tepung tersebut hampir sama, kandungan protein, lemak dan kalori lebih tinggi pada tepung tulang ikan percobaan pertama. Uji coba kedua tepung tulang ikan memiliki kandungan abu dan karbohidrat yang lebih tinggi. Sementara itu, kadar kalsium tepung tulang ikan pada uji coba kedua empat kali lipat dari uji coba pertama.
Kesimpulan: Kecukupan kalsium harian akan cukup dengan mengonsumsi 10 g tepung kalsium. Penelitian lebih lanjut diperlukan untuk mengetahui penyerapan kalsium dalam tubuh dan perngembangan konsumsi dalam bentuk aplikasi makanan.
Melania Perwitasari, Reza Anindita, Maya Uzia Beandrade
et al.
Antimicrobial resistance is one of the biggest health problems. Indonesia is a country with a positive high number of E. coli (71%) Extended Spectrum Beta Lactamase (ESBL) in the Asia Pacific. Many studies report that essential oils and extracts from several species of Ocimum have antimicrobial activity against gram-positive and negative bacteria. Antibacterial activity is related to active compounds contained in plants that are also affected by the place of growth, harvesting and post-harvesting. Research related to the activity of basil (Ocimum sanctum) that already exists does not provide complete and comprehensive data related to where to grow, harvest and post-harvest basil leaves. Basil leaves that have been set parameters for growth, harvest and post-harvest processes are extracted using maceration method with 70% etanol solvent and distilled to obtain essential oils (EO). Etanolic extract (EE) and EO were tested for their activity against Escherichia coli, Staphylococcus aureus and Salmonella thypii bacteria. The results showed that the basil leaves obtained from Margahayu sub-district, East Bekasi, had a dry simplicia yield of 12.8% ± 1.5, yield of EE 16.9% ± 1.6, EO content of 0.56%. The etanolic extract of basil leaves contains alkaloids, saponins, tannins, phenolics, flavonoids, glycosides, triterpenoids and steroids. The conclusion from the results of this study is the etanol extract and essential oils of basil leaves can inhibit the growth of bacteria, both basile leaves. The inhibition zone diameter is higher in gram positive bacteria (S. aureus) than gram negative bacteria (S. thypii and E. coli).
Abstract – School age is a productive age in the process of child development. Adequate nutrition is needed by children in the process of growth and development. Fulfillment of good nutrition will also have an impact on good health in children. In meeting nutritional needs, the family has an important role in determining children's nutritional behavior. Objective: to analyze the role of the family in fulfilling child nutrition. Methods: using descriptive quantitative research methods, using a cross section study research design with data collection techniques carried out using a random survey of 30 elementary school children. The method of data analysis was used to determine the relationship between the type of mother's work and the level of education with the fulfillment of child nutrition using descriptive analysis using the Chi square test (x2). Research Results: Mother's type of work has no significant effect on children's breakfast habits with a value of ρ-value = 0.369, but has a significant effect on the habit of carrying lunch with a value of ρ-value = 0.029. Meanwhile, mother's level of education has a significant relationship with breakfast habits with ρ-value = 0.024 and bringing lunch to school with ρ-value = 0.000081.

 Smoking is a bad habit that many people have, but this habit has a bad effect on health. One of the consequences of smoking is the formation of stains on the teeth. This study aims to determine the effect of smoking on the formation of stains on the teeth. This research is descriptive research, which aims to describe the condition of the respondents statistically. The research was conducted in November 2022. The research was carried out for one month by collecting respondent data from all puskesmas in Cirebon Regency, West Java. The research instruments used were interviews and checklists. The instrument records the age, length of smoking, shape of the cigarette and color of the respondent's teeth. Respondent criteria are active smokers from the age of 10 to 60 years and are willing to be research respondents. Respondents in this study numbered 112. The results showed that the color of the respondent's teeth were four colors, namely yellow, black, brown and dark brown. However, the most dominant tooth color was dark brown with a percentage of 55.4% or as many as 62 respondents out of 112 respondents. The conclusion of this study is that smoking can affect the formation of plaque on the teeth. Plaque formation on the teeth is most commonly found with dark brown teeth.
Suplemen bagi ibu hamil merupakan salah satu strategi pengobatan yang memiliki manfaat penting dalam pemenuhan gizi ibu hamil dengan gizi buruk dalam meningkatkan pertumbuhan janin. Salah satu strategi penanganan kasus stunting pada usia dini adalah dengan intervensi tambahan yang dapat berdampak pada penurunan kasus stunting. Tujuan dari penelitian ini untuk mengkaji secara sistematis intervensi suplemen ibu hamil dan manfaatnya dalam mencegah stunting. Tinjauan sistematis ini dilakukan dengan menggunakan daftar periksa PRISMA 2009. Penelitian ini menggunakan database yaitu PubMed, Cochrane Library, Springer Link, Base. Kriteria inklusi untuk penelitian ini adalah artikel bahasa Inggris dengan rancangan percobaan terkontrol acak (RCT) yang diterbitkan dalam 10 tahun terakhir. Penelitian ini menemukan bahwa tujuh penelitian memenuhi kriteria inklusi. Intervensi suplemen untuk ibu hamil dibagi menjadi tiga jenis suplemen, yaitu suplemen gizi berbasis lipid (LNS-SQ), suplemen seng, dan suplemen makanan berenergi protein yang dapat digunakan sebagai intervensi pencegahan stunting. Intervensi LNS-SQ dapat meningkatkan pertumbuhan janin tetapi perlu mempertimbangkan prosedur dan dosis intervensi, kandungan suplemen, dan efek samping intervensi. Intervensi suplemen menggunakan strategi pendekatan komunitas holistik yang berdampak positif pada pencegahan stunting.
Kawasaki disease (KD) is an acute systemic vasculitis frequently affecting children under five years old. KD can cause severe complications. It can lead to coronary aneurysms in 15-25% of untreated cases. Intravenous immunoglobulin (IVIG) treatment within ten days of initial onset can reduce the rate of coronary artery aneurysms. However, IVIG administration in Indonesia is currently limited due to its high cost. The case reported a 4-year-old girl with a chief complaint of fever. She complained about a high fever seven days before hospitalization. She also complained about vomiting, cough, joint pain, diarrhea, skin peeling, and rash on her body, palms, and soles. On examination, she looked irritable and sluggish. The temperature was 39.9o C. There were red eyes without discharge, strawberry tongue, oral thrush, and red, dry, cracked lips, swollen neck lymph nodes, and skin rash on her body, palms, and soles. Laboratory testing showed microcytic hypochromic anemia with Hb 7.9 g/dL and leukocytosis 24.230/mm3. Chest X-ray showed perihilar and paracardial infiltrates. Electrocardiogram revealed sinus tachycardia. An echocardiogram showed left ventricle dilatation with trivial mitral regurgitation and no coronary abnormalities were found. She was diagnosed with Kawasaki Disease. She was treated by IVIG 30 gr single dose during 12 hours on day 7 of initial onset, methylprednisolone injection 10 mg/8 hours, paracetamol 150 mg/8 hours, and aspirin 400 mg/8 hours orally and discharged from the hospital with improvement. There weren’t any coronary artery abnormalities found. IVIG administration within ten days of initial onset in KD patients can reduce the risk of coronary artery complications. IVIG administration after day 10 of initial onset can achieve resolution of inflammation but can be insufficient for preventing coronary artery lesions (CALs).
Stunting is one under-nutrition condition that might be caused by inadequate nutrition consumption or frequent infection. Stunting prevalence in primary school-age children (PSAC) is still high in the third world and Indonesia. This present paper aimed to study the prevalence and the associated factors such as sex, school-area, and food intakes of stunting in PSAC in Sidoarjo, 2018. This study is cross-sectional research using secondary data from baseline data of emotional demonstration projects in primary school students. Two hundred students were recruited from four schools representing urban and rural areas in Sidoarjo. Food intake was interviewed using SQ-FFQ. Children height was measured using microtoice. HAZ-score was calculated using WHO Anthro Plus software. Student t-test was done to test any differences in stunting prevalence between sex and school areas. The Chi-square test was used to check the difference in proportion for categories. Our results suggested the stunting prevalence among PSAC in Sidoarjo was 18% and was significantly greater in the rural area (p= 0,010). School location has association with stunting (OR= 2,7; 95%CI 1,25-5,8). In conclusion, we did not find any significant difference in food intakes, although stunted children were more likely to consume energy and carbohydrate. This condition must be considered to prevent obesity in stunted children
Nutrition. Foods and food supply, Food processing and manufacture
Latar belakang: Penyediaan pelayanan kesehatan mental sangat diperlukan mengingat pentingnya peran tenaga kesehatan dalam menangani Covid-19 serta tingginya beban psikologis tenaga kesehatan selama melayani pasien. Tujuan penelitian: Penelitian ini bertujuan untuk menganalisis rekomendasi pelayanan kesehatan mental bagi tenaga kesehatan pada masa pandemi Covid-19. Metode: Metode yang digunakan dalam penulisan artikel ini adalah literature review. Artikel didapatkan melalui database Google Scholar, Science Direct dan Pubmed yang dipublikasikan pada tahun 2020. Hasil penelitian: Berdasarkan hasil analisis artikel, terdapat berbagai masalah kesehatan mental dan rekomendasi guna menangani masalah tersebut pada tenaga kesehatan. Rekomendasi tersebut dikelompokkan menjadi tujuh upaya kesehatan mental yang terbagi dalam tahap response, recovery, dan mitigation pada disaster risk management. Kesimpulan: Berdasarkan tahap disaster risk management, tahap response membutuhkan upaya identifikasi risiko masalah kesehatan mental, pengaturan shift kerja dan pemberian dukungan tangible untuk mencegah dampak buruk pandemi bagi tenaga kesehatan. Upaya recovery dapat dilakukan dengan memberikan dukungan psikologis, dan reward. Upaya mitigation untuk mengurangi risiko masalah kesehatan mental dapat dilakukan dengan menyusun healthcare system preparedness dan meningkatkan keterampilan tenaga kesehatan.
Kata Kunci: Pelayanan Kesehatan Mental, Tenaga Kesehatan, Covid-19
Satrio Wibowo Rahmatullah, Eka Fitri Susiani, Muhammad Reza Fahlevi
et al.
Jeruk nipis (Citrus aurantifolia (Christm.) Swing) mengandung senyawa yang bermanfaat sehingga banyak digunakan dalam pengobatan tradisional. Penelitian ini bertujuan untuk mengetahui aktivitas antipiretik dari fraksi etil asetat kulit buah jeruk nipis. Hasil uji skrining fitokimia fraksi etil asetat kulit buah jeruk nipis mengandung senyawa flavonoid, saponin, alkaloid dan minyak atsiri. Sebanyak 25 ekor mencit dibagi menjadi 5 kelompok, kelompok I kontrol negatif, kelompok II kontrol positif, kelompok III, IV, V diberikan fraksi etil asetat dosis 0,07 %/20gBB, 0,105 %/20gBB dan 0,14 %/20gBB. Berdasarkan hasil grafik rata-rata penurunan suhu bahwa ketiga dosis tersebut memiliki aktivitas antipiretik karena dapat menurunkan suhu dan penurunan suhu terbesar pada dosis 0,14 %/20gBB. Berdasarkan hasil uji ANOVA diperoleh nilai sig. 0,000 yang berarti terdapat perbedaan suhu yang bermakna antar 5 kelompok perlakuan. Dan pada uji Independent Sample T-test antara kontrol positif dengan dosis 0,14 %/20gBB menghasilkan nilai sig. 0,601 (>0,05) yang berarti tidak terdapat perbedaan bermakna.
Latar Belakang: Salah satu masalah utama yang dialami remaja adalah masalah kesehatan reproduksi. SDKI (2012) yang menyatakan secara nasional terjadi peningkatan angka remaja yang melakukan hubungan seksual pranikah yaitu sekitar 9,3% atau sekitar 3,7 %. Hal ini akan berdampak meningkatnya masalah reproduksi remaja misalkan kehamilan yang tidak diinginkan, aborsi, penyakit menular seksual (PMS), serta kekerasan seksual. Hal tersebut disebabkan karena rendahnya pengetahuan dan sikap remaja tentang kesehatan reproduksi. Tujuan penelitian ini untuk mengetahui pengaruh pendidikan kesehatan terhadap peningkatan pengetahuan dan sikap remaja tentang kesehatan reproduksi dan penyakit menular seksual. Rancangan penelitian ini menggunakan eksperimen semu (Quasi exsperimen), dengan pendekatan one group pre test – post test design tanpa kelompok control. Populasi pada penelitian ini adalah 105 remaja, Sampel yang digunakan dalam penelitian ini berjumlah 56 orang dengan tehnik pengambilan sampel Purposive Sampling. Hasil penelitian menunjukan hasil uji Wilcoxon didapatkan p-value = 0,000 < 0,05 yang berarti terdapat perbedaan bermakna antara tingkat pengetahuan dan sikap remaja sebelum dan sesudah pemberian pendidikan kesehatan. Kesimpulan bahwa pendidikan kesehatan memberikan pengaruh yang signifikan pada tingkat pengetahuan dan sikap remaja tentang kesehatan reproduksi dan penyakit menular seksual.
Bureaucratic discretion in regional government as an effort to publish public service effectiveness in a state of urgency, which is a situation that emerges suddenly concerning the public interest that must be resolved quickly, where to resolve the issue, laws and regulations have not yet regulated it. Constraints In bureaucratic discretion in local government as one of the efforts in the effectiveness of public services is the insufficient cost due to excessive demand from the bureaucratic discretion program, policy participants who swell are not in accordance with the established plans, for example, participants who are not categorized as poor but ask to be classified as poor families and administrative services are not smooth because the bureaucratic discretion policy is more a spontaneous program from the local government. The ideal discretion model to overcome the problem of delegation of authority that occurs during diving This is to provide additional competency training in medical action to nurses with the aim that nurses are able to provide limited medical treatment services in accordance with the duties and authorities listed in the Nursing Act. In the development of public administration so many dynamics arise, starting from the role of separate public administration at all with the political world. The next understanding that then emerged was that administration was part of politics. The paradigm that arises is "when political ends administration begins". These understandings later led to many opinions both from scientists and practitioners to re-explore the essence of the science of public administration. Regional governments need to take legal action of discretion (freies ermessen) for those in remote or rural areas. The discretion is all activities that involve the process of policy making or decision making or action on its own initiative, not fixed on the provisions of the rules or laws with a variety of mature, contextual and accountable considerations
Nur Syarianingsih Syam, Selvi Novita Sari, Siti Kurnia Widi Hastuti
Hospitals are a high-risk workplace for the safety and health of Human Resources (HR). Control of sources and potential hazards in hospitals can be done with the use of Personal Protective Equipment (PPE). PPE consists of gloves, masks, face/eye protection, protective gowns, and leg protectors. The purpose of this study was to evaluate the use of PPE on health workers in Bantul X Yogyakarta Hospital. This research used descriptive qualitative method with a phenomenological design. Data collection used interview guidelines for 5 informants who were selected based on the purposive method or fulfillment of certain criteria and carried out the observation of the use of PPE to 30 health workers. The results of the research related to input indicate that there are policies and standard operating procedure for the use of PPE in nursing care actions. It is also known that health care workers have received information and training on how to use PPE and personal protective equipment were always available and in accordance with the indications of actions in the central operating room unit, inpatient room, and Central Sterile Supply Departement. The results of observations of the level of PPE use in health workers (the process of use masks used by 30 officers, gloves 24 officers, dresses/ aprons 15 officers, head cover 15 officers and no activities were found with an indication of the use of goggle at the time of observation. it can be concluded that the use of PPE in hospital X Bantul has not met Permenkes standards, both in terms of the number of users (output) and in terms of the use process.
Madyawati Latief, Muhaimin Muhaimin, Hilda Amanda
et al.
Abroma augusta L plant traditionally was used to treat swellings, cuts, sores, and bruises. In the province of Jambi, A. augusta is used in folk medicine to treat wounds. This study aims to isolate the steroid compound from the root of A. augusta L and determine its anti-inflammatory activities. Extraction and fractionation have been done with graded maceration using solvents with different polarities, which are n-hexane, ethyl acetate, and methanol. The separation was performed by column chromatography, followed by preparative thin-layer chromatography. The characterization of the isolate was carried out using UV-Vis spectrophotometry and infrared spectrophotometry, GC-MS. The anti-inflammatory activities of methanol extract and isolate of A. augusta was performed in this study was designed to evaluate the dose-response relationship of the anti-inflammatory activity in rat models of chronic inflammation chromatography to obtain isolate 2.1.1 that characterize and showed maximum absorbance at 265. The result of IR showed the presence of functional groups, -C=C-H, -C=H, -CH, CH3, CH2, and –CO belongs to the steroid compound. The results of the GC-MS show that isolates contain squalene compounds with a value of m/z 410, Isolate and crude extract showed an anti-inflammatory activity that almost approached the positive control of sodium 4-chlorophenolate. It could be concluded that isolate and extract provide good anti-inflammatory activity, that promise for new drug candidate squalene-based A. augusta.
Penelitian ini bertujuan untuk mengetahui kandungan metabolit sekunder dan aktivitas sitotoksik dengan nilai LC50dari ekstrak selada merah (Lactuca sativa var.Crispa) pada berbagai pelarut. Sampel selada merah yang digunakan didapatkan dari desa Turirejo kecamatan Lawang-Malang. Simplisia selada merah di ekstraksi dengan metode maserasi menggunakan variasi pelarut yaitu pelarut etanol, metanol, etil asetat, dan n-heksana selama 24 jam. Hasil maserasi dipekatkan dengan alat rotary vacuum evaporator. Kemudian dilakukan uji skrining fitokimia serta KLT untuk mengetahui kandungan metabolit sekunder dalam sampel. Pengujian aktivitas sitotoksik dilakukan dengan metode BSLT (Brine Shrimp Lethality Test). Hasil ekstraksi didapatkan ekstrak kental etanol, metanol, etil asetat, dan n-heksana secara berturut-turut sebesar 17,30 g; 12,32 g; 25,61 g; dan 3,76 g. Dan hasil dari uji fitokimia menunjukkan ekstrak etanol selada merah mengandung flavonoid, tanin, saponin, triterpenoid, steroid dan alkaloid. Sedangkan ekstrak metanol selada merah mengandung alkaloid, saponin, dan tanin. Pada ekstrak etil asetat selada merah mengandung alkalid, saponin, steroid, dan tanin. Dan pada ekstrak n-heksana selada merah mengandung alkaloid, steroid, triterpenoid, dan tanin. Hasil aktivitas sitotoksik ekstrak metanol memiliki bioaktivitas tertinggi terhadap Artemia salina Leach. dibandingkan dengan ekstrak etanol, etil asetat, dan n-heksana. Nilai LC50ekstrak etanol, metanol, etil asetat, dan n-heksana secara berturut-turut adalah 322,288 ppm; 68,632 ppm; 1934,287 ppm; dan 170,115 ppm.
Kata kunci: Selada merah (Lactuca sativa var. Crispa), sitotoksik, Artemia salina Leach, BSLT.
Susanti Pratamaningtyas, Shinta Kristianti, Siti Nurhidayatul Ilma Nafiah
Preeclampsia is a special condition during pregnancy where hypertension and proteinuria occur after 20 weeks of gestation in mothers who have had normal blood pressure. Symptoms that arise in preeclampsia are edema, hypertension, and proteinuria. One of the factors that make incidence of preeclampsia is obesity. Women with abnormal weight have a greater risk of preeclampsia. The purpose of this study was to determine the relationship of weight gain during pregnancy to the incidence of preeclampsia in Gambiran Hospital, Kediri. Simple random sampling was used with a population of 117 mothers. 91 mothers were taken to be respondents, this study was conducted on 6-9 May 2019. The research instrument used recapitulation sheet. The results of statistical tests showed that there was a relationship between weight gain during pregnancy and the incidence of preeclampsia in Gambiran Hospital, Kediri City. The Chi Square test results show that the value of Ï value is 0.022, then 0.022 <0.05, so it can be concluded that there is a Relationship between Increasing Weight During Pregnancy with the incidence of Preeclampsia in Gambiran Hospital, Kediri City.
Penelitian ini bertujuan untuk mengetahui dampak pola hidup terhadap kebugaran siswa XI IPS 1 SMA Negeri 8 Kota Bengkulu. Jenis penelitian ini adalah deskriptif kualitatif. Populasi dan sampel yang digunakan dalam penelitian ini adalah seluruh siswa kelas XI IPS 1 SMA Negeri 8 Kota Bengkulu yang berjumlah 35 orang. Instrumen yang digunakan angket tertutup dan tes lari 2.400 meter. Teknik pengumpulan data penelitian menggunakan angket dan tes. Teknik analisis data menggunakan teknik analisis data triangulasi dan statistic deskriptif (tabulasi frekuensi). Berdasarkan hasil penelitian hasil data diproleh sehingga dibagi menjadi 2 keriteria yaitu 22 laki-laki dan 13 perempuan ternyata rata-rata kecakapan dalam dampak pola hidup terhadap kebugaran jasmani pada siswa kelas XI IPS 1 SMA Negeri 8 Kota Bengkulu untuk laki-laki dikategorikan kurang atau 12,29% ,sedangkan perempuan sebagian besar berkategori sedang atau 16,38%. Adapun hasil angket dapat ditarik simpulan dari jawaban responden Siswa XI IPS 1 SMA Negeri 8 Kota Bengkulu memiliki kesehatan dan kebugaran yang belum terpenuhi. Pola hidup siswa belum banyak mendapat pemahaman tentang pembelajaran pola hidup dan kebugaran yang benar.
Background: Hypertension becomes a serious problem since one in three adults worldwide suffers from hypertension. Hypertension is the third highest cause of death in Indonesia at all ages with the proportion of deaths of 6.83%. Purpose: This study aims to determine the relationship of lifestyle with hypertension in Dusun Sendang Anyar and Tambakrame Desa Bumiayu Kecamatan Baureno Kabupaten Bojonegoro. Methods: This research was done for a month from July to August 2017. This research type is descriptive with cross sectional research design. The population study were 150 family heads who have at least one family member aged ≥40 years. Sampling method using cluster random sampling, obtained sample of 101 family heads. Independent variable in this study is hypertension, while the dependent variable is lifestyle that includes sports habits, smoking, consumption of salted fish, spinach, banana, and frying food. Data analysis using chi square statistic test with significance level of 95% and α = 5%. Results: This study showed that the variables related to hypertension were sports habit (p = 0.01), smoking (p = 0.01), consumption of salted fish (p = 0.01), consumption of spinach (p = 0.01), consumption of banana (p= 0.02). Variable unrelated to hypertension was consumption of frying food (p = 0.23). Conclusion: There were correlation between exercise habits, smoking, consumption of salted fish, consumption of spinach, and consumption of banana with hypertension.
Public aspects of medicine, Infectious and parasitic diseases