Hasil untuk "History of Spain"

E. Tarín-Vicente, A. Alemany, M. Agud‐Dios et al.

Background In May, 2022, several European countries reported autochthonous cases of monkeypox, which rapidly spread globally. Early reports suggest atypical presentations. We aimed to investigate clinical and virological characteristics of cases of human monkeypox in Spain. Methods This multicentre, prospective, observational cohort study was done in three sexual health clinics in Madrid and Barcelona, Spain. We enrolled all consecutive patients with laboratory-confirmed monkeypox from May 11 to June 29, 2022. Participants were offered lesion, anal, and oropharynx swabs for PCR testing. Participant data were collected by means of interviews conducted by dermatologists or specialists in sexually transmitted infections and were recorded using a standard case report form. Outcomes assessed in all participants with a confirmed diagnosis were demographics, smallpox vaccination, HIV status, exposure to someone with monkeypox, travel, mass gathering attendance, risk factors for sexually transmitted infections, sexual behaviour, signs and symptoms on first presentation, virological results at multiple body sites, co-infection with other sexually transmitted pathogens, and clinical outcomes 14 days after the initial presentation. Clinical outcomes were followed up until July 13, 2022. Findings 181 patients had a confirmed monkeypox diagnosis and were enrolled in the study. 166 (92%) identified as gay men, bisexual men, or other men who have sex with men (MSM) and 15 (8%) identified as heterosexual men or heterosexual women. Median age was 37·0 years (IQR 31·0–42·0). 32 (18%) patients reported previous smallpox vaccination, 72 (40%) were HIV-positive, eight (11%) had a CD4 cell count less than 500 cells per μL, and 31 (17%) were diagnosed with a concurrent sexually transmitted infection. Median incubation was 7·0 days (IQR 5·0–10·0). All participants presented with skin lesions; 141 (78%) participants had lesions in the anogenital region, and 78 (43%) in the oral and perioral region. 70 (39%) participants had complications requiring treatment: 45 (25%) had a proctitis, 19 (10%) had tonsillitis, 15 (8%) had penile oedema, six (3%) an abscess, and eight (4%) had an exanthem. Three (2%) patients required hospital admission. 178 (99%) of 180 swabs from skin lesions collected tested positive, as did 82 (70%) of 117 throat swabs. Viral load was higher in lesion swabs than in pharyngeal specimens (mean cycle threshold value 23 [SD 4] vs 32 [6], absolute difference 9 [95% CI 8–10]; p<0·0001). 108 (65%) of 166 MSM reported anal-receptive sex. MSM who engaged in anal-receptive sex presented with proctitis (41 [38%] of 108 vs four [7%] of 58, absolute difference 31% [95% CI 19–44]; p<0·0001) and systemic symptoms before the rash (67 [62%] vs 16 [28%], absolute difference 34% [28–62]; p<0·0001) more frequently than MSM who did not engage in anal-receptive sex. 18 (95%) of 19 participants with tonsillitis reported practising oral-receptive sex. The median time from onset of lesions to formation of a dry crust was 10 days (IQR 7–13). Interpretation In our cohort, monkeypox caused genital, perianal, and oral lesions and complications including proctitis and tonsillitis. Because of the variability of presentations, clinicians should have a low threshold for suspicion of monkeypox. Lesion swabs showed the highest viral loads, which, combined with the history of sexual exposure and the distribution of lesions, suggests close contact is probably the dominant transmission route in the current outbreak. Funding None.

D. Huremović

Intermittent outbreaks of infectious diseases have had profound and lasting effects on societies throughout history. Those events have powerfully shaped the economic, political, and social aspects of human civilization, with their effects often lasting for centuries. Epidemic outbreaks have defined some of the basic tenets of modern medicine, pushing the scientific community to develop principles of epidemiology, prevention, immunization, and antimicrobial treatments. This chapter outlines some of the most notable outbreaks that took place in human history and are relevant for a better understanding of the rest of the material. Starting with religious texts, which heavily reference plagues, this chapter establishes the fundamentals for our understanding of the scope, social, medical, and psychological impact that some pandemics effected on civilization, including the Black Death (a plague outbreak from the fourteenth century), the Spanish Flu of 1918, and the more recent outbreaks in the twenty-first century, including SARS, Ebola, and Zika.

Ever Lezcano González, Velislava Simeonova Simeonova, Nathalia Beatriz Ibarrola Florentin

The Paraguayan spatial planning system is analyzed through its legal framework, institutional structure, and implementation mechanisms, placing it within the Latin American context marked by fragmented governance and institutional inequality. Based on a review of laws and planning instruments at the national, departmental, and municipal levels, this study examines the system’s evolution, with particular focus on the period from the consolidation of the constitutional framework to the formulation of recent policies promoting sustainable development, decentralization, and democratic decision-making. The findings show a process of partial institutionalization, where norms and methodologies advance more rapidly than operational and financial capacities, resulting in uneven implementation across regions. Ongoing challenges include regulatory fragmentation, overlapping responsibilities, and weak multilevel coordination. Enhancing institutional coherence, prioritizing planning instruments, and strengthening subnational technical capacities are key to achieving a coherent and equitable spatial planning system that integrates international cooperation and translates sustainability and equity principles into practical dimensions of territorial governance.

Franc Capdevila Finestres, Daida Alberto Armas, Antoni Miró Manzano et al.

<b>Introduction:</b> Omeprazole is commonly prescribed for conditions associated with excess gastric acid, including gastroesophageal reflux and <i>Helicobacter pylori</i> infection. Spain ranks highest among Organization for Economic Co-operation and Development (OECD) countries in omeprazole consumption (measured in doses per 1000 inhabitants per day, DHD), indicating potential overuse and misuse. Community pharmacists are pivotal in collaborating with healthcare professionals to address safety risks and improve patient outcomes. <b>Objective:</b> This study aims to profile omeprazole users to inform pharmaceutical care (PC) strategies that address patient-specific needs and improve treatment safety. <b>Methods:</b> We conducted an observational, cross-sectional study (CEIm Code FCF-OME-2023-01) involving 100 omeprazole users at a community pharmacy in Barcelona from November 2023 to May 2024. Data were collected via clinical interviews using a Data Collection Questionnaire. <b>Results:</b> Among the omeprazole users, 49% were male, 51% female, and 56% were over the age of 65. A significant proportion (71%) exhibited long-term omeprazole use, and 30% were polymedicated (taking five or more medications). Notably, 52% of patients reported no history of gastric symptoms. Additionally, 22% reported using omeprazole occasionally, following short-term, on-demand treatment regimens, while 78% adhered to a chronic daily dosing schedule. Among these patients, 29.5% demonstrated poor treatment adherence. The analysis of medication-related problems (MRPs) among the 78 patients using omeprazole daily and chronically revealed that the most prevalent MRPs were “unnecessary medication”, “lack of adherence”, “wrong administration”, “drug interactions”, and “lack of knowledge regarding medication use”. Based on STOPP criteria, 45% of users were candidates for deprescribing or dose adjustment. <b>Conclusions:</b> The high incidence of MRPs among omeprazole users highlights the need for enhanced pharmaceutical care (PC). Proactive pharmacist interventions, including deprescribing, dose adjustments, and prescriber collaboration, can reduce adverse medication outcomes and promote safer omeprazole use.

Annemarie McAllister

Michela Coletta (m.coletta@warwick.ac.uk) is Assistant Professor in Hispanic Studies at the University of Warwick and Marie Sklodowska-Curie Fellow at Freie Universität Berlin. She is author of Decadent Modernity: Civilisation and Latinidad in Spanish America, 1880-1920 (LUP 2018) and co-editor of Provincialising Nature: Multidisciplinary Approaches to the Politics of the Environment in Latin America (University of London Press 2016). Her latest article, 'Critical Border Zones and Anti-extractive Knowledge: Perspectives from the Andean World’, was published in the Radical History Review in early 2023.

G. Rojo-Martínez, S. Valdés, F. Soriguer et al.

Our aim was to determine the incidence of type 2 diabetes mellitus in a nation-wide population based cohort from Spain (di@bet.es study). The target was the Spanish population. In total 5072 people older than 18 years,were randomly selected from all over Spain). Socio-demographic and clinical data, survey on habits (physical activity and food consumption) and weight, height, waist, hip and blood pressure were recorder. A fasting blood draw and an oral glucose tolerance test were performed. Determinations of serum glucose were made. In the follow-up the same variables were collected and HbA1c was determined. A total of 2408 subjects participated in the follow-up. In total, 154 people developed diabetes (6.4% cumulative incidence in 7.5 years of follow-up). The incidence of diabetes adjusted for the structure of age and sex of the Spanish population was 11.6 cases/1000 person-years (IC95% = 11.1–12.1). The incidence of known diabetes was 3.7 cases/1000 person-years (IC95% = 2.8–4.6). The main risk factors for developing diabetes were the presence of prediabetes in cross-sectional study, age, male sex, obesity, central obesity, increase in weight, and family history of diabetes. This work provides data about population-based incidence rates of diabetes and associated risk factors in a nation-wide cohort of Spanish population.

Nuria Corral Sánchez, Cristina Erquiaga Martínez

Presentación

Weronika Barbara Żukowska, Błażej Wójkiewicz, Andrzej Lewandowski et al.

Abstract Key message The range-wide level of genetic variation of Scots pine (Pinus sylvestris L.) is geographically structured. High admixture and low genetic structure of populations in Central Europe and Fennoscandia suggest past recolonization from multiple sources and the influence of human-mediated gene transfer. Gene pools of marginal and isolated stands require active conservation. Some areas of Scots pine distribution need further genetic studies. Context Scots pine (Pinus sylvestris L.) seems to be a species of low conservation priority because it has a very wide Eurasian distribution and plays a leading role in many forest tree breeding programs. Nevertheless, considering its economic value, long breeding history, range fragmentation, and increased mortality, which is also projected in the future, it requires a more detailed description of its genetic resources. Aims Our goal was to compare patterns of genetic variation found in biparentally inherited nuclear DNA with previous research carried out with mitochondrial and chloroplast DNA due to their different modes of transmission. Methods We analyzed the genetic variation and relationships of 60 populations across the distribution of Scots pine in Eurasia (1262 individuals) using a set of nuclear DNA markers. Results We confirmed the high genetic variation and low genetic differentiation of Scots pine spanning large geographical areas. Nevertheless, there was a clear division between European and Asian gene pools. The genetic variation of Asian populations was lower than in Europe. Spain, Turkey, and the Apennines constituted separate gene pools, the latter showing the lowest values of all genetic variation parameters. The analyses showed that most populations experienced genetic bottlenecks in the distant past. Ongoing admixture was found in Fennoscandia. Conclusions Our results suggest a much simpler recolonization history of the Asian than European part of the Scots pine distribution, with migration from limited sources and possible founder effects. Eastern European stands seem to have descended from the Urals refugium. It appears that Central Europe and Fennoscandia share at least one glacial refugium in the Balkans and migrants from higher latitudes, as well as from south-eastern regions. The low genetic structure between Central Europe and Fennoscandia, along with their high genetic admixture, may result at least partially from past human activities related to the transfer of germplasm in the nineteenth and early twentieth centuries. In light of ongoing climate changes and projected range shifts of Scots pine, conservation strategies are especially needed for marginal and isolated stands of this species. Genetic research should also be complemented in parts of the species distribution that have thus far been poorly studied.

Samantha Brunel, E. Bennett, Laurent Cardin et al.

Significance Using genomic data as well as paternal and maternal lineages from more than 200 individuals, including 58 low-coverage ancient genomes, we show the population structure from the Mesolithic to the Iron Age in France and trace the changing frequency of genotypes associated with phenotypic traits. Importantly, we also report the late persistence of Magdalenian-associated ancestry in hunter-gatherer populations, showing the presence of this ancestry beyond the Iberian Peninsula in the Late Paleolithic. This study complements the genomic history of western Europe for this broad period by supplying a large genetic transect of three regions of France. Genomic studies conducted on ancient individuals across Europe have revealed how migrations have contributed to its present genetic landscape, but the territory of present-day France has yet to be connected to the broader European picture. We generated a large dataset comprising the complete mitochondrial genomes, Y-chromosome markers, and genotypes of a number of nuclear loci of interest of 243 individuals sampled across present-day France over a period spanning 7,000 y, complemented with a partially overlapping dataset of 58 low-coverage genomes. This panel provides a high-resolution transect of the dynamics of maternal and paternal lineages in France as well as of autosomal genotypes. Parental lineages and genomic data both revealed demographic patterns in France for the Neolithic and Bronze Age transitions consistent with neighboring regions, first with a migration wave of Anatolian farmers followed by varying degrees of admixture with autochthonous hunter-gatherers, and then substantial gene flow from individuals deriving part of their ancestry from the Pontic steppe at the onset of the Bronze Age. Our data have also highlighted the persistence of Magdalenian-associated ancestry in hunter-gatherer populations outside of Spain and thus provide arguments for an expansion of these populations at the end of the Paleolithic Period more northerly than what has been described so far. Finally, no major demographic changes were detected during the transition between the Bronze and Iron Ages.

H. Klein

Bolivia is an unusually high-altitude country created by imperial conquest and native adaptions – today, it remains one of the most multi-ethnic societies in the world with one of the largest Amerindian populations in the Americas. It has seen the most social and economic mobility of Indian and mestizo populations in any country in Latin America. This work, having also appeared in Spanish, Portuguese, Japanese and Chinese in its earlier editions, has become the standard survey of the history of Bolivia. In this new edition, Klein explores the changes that occurred in the past two decades under the leadership of Evo Morales and his indigenous government, and how his party has emerged in the post-Evo years as one of the most important in Bolivia. The work also expands on the changes in both the traditional mining economy and the rise of a new commercial export agriculture.

Jennifer Ruiz-Morgan

The tragic story of the star-crossed lovers of Verona was first presented to Spanish theatergoers during the early decades of the nineteenth century. During this period Shakespeare was largely unknown to the general public. The article examines the early reception of Shakespeare in Spain focusing on one iconic play, Romeo and Juliet, and its earliest adaptations: Dionisio Solís’s Julia y Romeo (1803) and Manuel Bernardino García Suelto’s Romeo y Julieta (1817). At a time when the Spanish public was captivated by the allure displayed by adaptations of Othello, this article argues that the adaptations of Romeo and Juliet composed by Solís and García Suelto also enjoyed popularity, as evidenced by their several revivals and the prestige of some of the actors and actresses who intervened in the productions. The article examines the historical, political and sociocultural factors that contributed to the composition and popularity of Julia y Romeo and Romeo y Julieta. Historical contextualization is combined with an analysis of the sources and main features of each adaptation. The article also offers a detailed account of the reception and performance history of both plays on the Spanish stage from 1803 to 1836. These neoclassical versions remain –up to this day– largely unknown texts, but they deserve close attention since both plays strongly contributed to the gradual dissemination of Shakespeare and his work in Spain.

Betsy Barber-O'Malley, Géraldine Lassalle, Patrick Lambert et al.

EuroDiad version 4.0 is a set of data tables that store information about the presences/absences and population functionality of diadromous species (lampreys and fish) populations in selected catchments in Europe, the Middle East, and North Africa from 1750 to present time. This database contains distribution and life-history trait information for twenty-eight European diadromous species and geomorphological data for each of the selected catchments, though not every species has data for every catchment and time period. EuroDiad was originally created in 2005–2006 (EuroDiad 1.0 and 2.0), and contained data for 196 catchments and two time periods (1851–1950 and 1951–2010). It underwent a major update in 2009–2010 (EuroDiad 3.2) through a validation process by European fisheries experts. Version 3.2 included the addition of 63 small-sized catchments (< 10,000 km2) and an additional time period (1751–1850) for select species and catchments. This database underwent a second validation process in 2019–2020 and was updated to v 4.0, with the primary goal of providing information for a new generation of species distribution models, referred to as hybrid models, which incorporate both habitat suitability and population dynamics within their framework. Secondary objectives of this update were to: (a) incorporate new catchments for which information was provided by additional experts, (b) validate existing information about the presences or absences of diadromous species and categorize their population functionality within a catchment, and (c) perform data hygiene to prepare the database for broad dissemination. Information on the life history, morphology, and phenology of four emblematic species (i.e. eel, salmon, lamprey and shad) were added in this occasion. Data for this update were validated by DiadES project partners (www.diades.eu) and local experts. This update was focused on catchments located in the Atlantic Area for use in the DiadES project. Data were divided by country, and validation was performed for catchments in Ireland, the U.K., Spain, Portugal, and France under the supervision of national organisations in fisheries and environmental management. DiadES project partners were asked to validate geomorphological information for the catchment (location of the outlet, surface area of the drainage basin, length of the main watercourse, elevation at the headwaters), as well as the presences/absences information and population functionality categories for all species already present in EuroDiad for their country. If possible, verification was done for each of the three time periods. Partners were also asked to provide data for any other catchments for which they had access to information on fish population status. EuroDiad 4.0 now stores data for 350 catchments (of which 292 have population functionality records) and three time periods, though the precision of information varies and not every species has information for each time period. This validation process strengthened the usefulness of EuroDiad, which is now updated and available for use by the research community.

Mike Wayne, Deborah Castro

This article compares the processes by which Netflix entered national pay-television markets in Israel and Spain. In both contexts, Netflix first establishes itself through collaborations with over-the-top (OTT) television operators and then expands through collaborations with legacy providers. By using the perspective of cross-national comparative research, this analysis complicates the scholarly understandings of subscription video on-demand (SVOD) global expansion by drawing attention to the significance of national multichannel providers. Given the differences between the Spanish and Israeli pay-TV markets, Netflix’s similar pattern of engagement in each case highlights the value of understanding SVOD global expansion as a coherent industrial process that produces distinct, context-dependent outcomes. Ultimately, the histories of Netflix in Israel and Spain reveal that internationalization operates at a meso-level where collaborations with pay-television providers facilitate access to national audiences.

S. Dworkin

From an historical perspective, the Spanish lexicon consists of three different categories: (1) its historical core of words inherited from the Latin spoken in the Roman province of Hispania; (2) loanwords that entered Spanish over its long history as a result of contact at the levels of both oral and written discourse with other languages; and (3) words created internally through such mechanisms of derivational morphology as suffixation, prefixation, compounding, back-formations, and so on. Over the last 150 years, specialists in the history of the Spanish language have studied in considerable detail all three sources of lexical material. Although most of the lexical items inherited from spoken Latin have cognates in many (in some cases, all) of the Romance languages, Spanish has preserved some words that live on only in Spanish (and neighboring Portuguese) or only in Spanish, Portuguese, and Romanian, the geographical extremes of the Romance-speaking world, far removed from the centers of linguistic innovation. As a result of language contact, loanwords from the pre-Roman languages of the Iberian Peninsula, Visigothic, Arabic, Gallo-Romance (northern and southern French), Portuguese, Catalan, Italian, classical Latin, native languages of the New World, and English have entered and taken root in the Spanish lexicon. Although such lexical borrowings have often been studied within a cultural framework, recent research has focused on their introduction and incorporation as examples of contact-induced language change at the level of the lexicon. Throughout its history, Spanish has increased the size of its vocabulary through the creation of neologisms through processes of suffixation, prefixation, and composition. The study of such items has traditionally been the focus of specialists in diachronic derivational morphology. This subfield constitutes in many respects an important component of diachronic lexicology. Indeed, etymology and diachronic derivational morphology are two sides of the same coin. Lexical history is not limited to the study of additions to the vocabulary. Over time, many words have fallen into disuse or have become obsolete. Some recent work on the history of the Spanish lexicon has examined the various external and internal/structural causes of lexical loss in the history of the Spanish lexicon.

Nadia Andrea de Cristóforis

Los españoles han constituido históricamente uno de los principales grupos de extranjeros en la Argentina, ubicándose numéricamente detrás de los italianos. A lo largo de los siglos XIX y XX la comunidad hispánica establecida en el país austral experimentó destacadas variaciones demográficas: creció abruptamente desde 1895 hasta 1914, alcanzó una dimensión máxima en este último año y luego comenzó a disminuir, de manera más pronunciada a partir de 1960.1 La ciudad de Buenos Aires concentró la mayor cantidad de españoles dentro del país: según el Tercer Censo Nacional, hacia 1914 residían en ella unos 306.850 peninsulares, que representaban alrededor del 20% de la población total allí asentada.2 Estos inmigrantes, junto a los que llegaron posteriormente, generaron un amplio movimiento asociativo, con nstituciones y producciones culturales propias, al tiempo que se insertaron en espacios económico-sociales y políticos de distinto tipo, con resultados variables.

MB Mateo Borrega, B. García, C. Larramendi et al.

BACKGROUND The aims of this study were to investigate the prevalence of sIgE to galactose-alpha-1,3-galactose (α-gal) in individuals with acute urticaria or anaphylaxis from different geographical areas of Spain and to evaluate the relevance of demographics and lifestyle as risk factors for this immune response. METHODS Participants were recruited from allergy departments at 14 Spanish hospitals. Patients aged 18 years or older presenting with urticaria or anaphylaxis were enrolled into one of two arms: cases and controls. An interviewer-administered questionnaire collecting demographic data, lifestyle habits, and the presence of cofactors was obtained from each participant. sIgE to α-gal and total IgE were determined using ImmunoCAP®. sIgE levels ≥0.35 kU/l were considered a positive result. RESULTS The study population comprised 160 cases and 126 controls. The median age was 44 years. The overall prevalence of a positive result of sIgE to α-gal was 15.7%; this was higher in cases (26.3%) than in controls (2.4%). The sIgE anti α-gal positivity rate ranged from 37.68% (rural) to 15.38% (semi-urban) and 7.85% (urban). The rates of positivity were 46.32%, (Northern), 0.72% (Center), and 0% (Mediterranean). A positive result of sIgE to α-gal associated with history of tick bites, participation in outdoor activities, pet ownership, and ingestion of mammalian meats or innards before the onset of symptoms. Only alcohol consumption could be implicated as a cofactor. CONCLUSIONS Sensitization to α-gal in patients with urticaria or anaphylaxis differs considerably between the three geographical areas studied and is related to tick bites.

Stephen B. Acabado, J. Koller, Chin‐hsin Liu et al.

ABSTRACT Establishing the construction sequence of agricultural terraces is extremely complicated due to the nature of their technological foundation and use. A number of methodological approaches have been developed to address this difficulty, such as bulk soil 14C dating, Optically-Stimulated Luminescence (OSL), sediment grain size, or a combination of these, but a fundamental problem of stratigraphic disturbance still exists. In this article, we utilize multiple datasets, including radiocarbon determinations, faunal isotopic signatures, human osteological remains, archaeobotanical data sets, energetics assessments, and spatial data to establish the origins of Philippine Cordillera rice terraces. Dominant historical narratives in the region suggest a 2000–3000 b.p. inception of the terrace systems, but previous Bayesian modeling and current archaeobotanical, ethnohistorical, and ethnographic data indicate that the shift to wet-rice cultivation is a recent phenomenon and a response to the intrusion of the Spanish Empire in the northern highland Philippines.

Rosina Lozano

D. Ranson, M. Quesada

This concise textbook provides students with an engaging and thorough overview of the history of Spanish and its development from Latin. Presupposing no prior knowledge of Latin or linguistics, students are provided with the background necessary to understand the history of Spanish. Short, easy-to-digest chapters feature numerous practice exercises and activities. Chapter “lead-in” questions draw comparisons between English and Spanish, enabling students to use their intuition about their native language to gain a deeper understanding of Spanish. Each chapter features further reading suggestions, an outline, and a summary. Highlighted key terms are collated in a glossary. Boxes on linguistic debates teach students to evaluate arguments and think critically about linguistics. Supporting online resources include Word files of all the practices and activities in the book and an instructor’s manual featuring a sample syllabus, answer key to the practices and activities, sample exams and teaching suggestions. This book is ideal for a range of courses on the history of Spanish and Spanish linguistics.

E. Angelakis, Y. Bechah, D. Raoult