Sarin Suwanpakdee, Anuwat Wiratsudakul, Nattarun Chaisilp
et al.
Abstract The canine distemper virus (CDV) could infect various wildlife species worldwide. The viral infection in large felids directly impacts wildlife conservation. This study aimed to understand better the burden of CDV outbreaks in captive tiger populations in Thailand and a novel discovery of their clinical signs with a history of CDV exposure. We followed up on their infection from June 2016 to October 2020 with laboratory testing and veterinary medical records. The cumulative morbidity and mortality rates were relatively high. Moreover, 50% of the tigers survived at 2 years after infection. Approximately 38% of CDV infections were detected with laryngeal inflammation, which developed into paralysis in almost 50% of cases. Altogether, 50% of tigers with chronic infection developed stridor at 314 days after virus infection [95% CI: 302–320]. Our data indicates that laryngeal paralysis resulted from the CDV infection, potentially affecting the peripheral and central nervous systems. This condition can pose a life-threatening risk to tigers. The virus can spread quickly by contact with bodily excretion among tigers and fomite contamination once it affects a specific population. Implementation of biosecurity measures and vaccination is essential to mitigate the risk of disease spread and infection rates in tiger populations.
First-class constraints constitute a potential obstacle to the computation of a Poisson bracket in Dirac's theory of constrained Hamiltonian systems. Using the pseudoinverse instead of the inverse of the matrix defined by the Poisson brackets between the constraints, we show that a Dirac-Poisson bracket can be constructed, even if it corresponds to an incomplete reduction of the original Hamiltonian system. The uniqueness of Dirac brackets is discussed.
Susana B. Bravo, Jorge E. Caminos, Carmen R. González
et al.
The stomach secretes a wide range of peptides with essential metabolic functions, and thereby plays an important role in the regulation of energy homeostasis. Disulfide isomerase glucose-regulated protein 58 (GRp58) is a molecular chaperone member of the endoplasmic reticulum (ER) stress signaling pathway, which is a marker for human gastric cancer. Since GRp58 seems to be regulated by a phosphorylation/dephosphorylation pattern shift, we used the 2DE gel methodology and peptide mass fingerprinting-protein identification by means of MALDI-TOF mass spectrometry. We show that gastric mucosa GRp58 is dephosphorylated by fasting, and this effect is blunted when fasted rats are treated with leptin. Furthermore, we assessed the gene expression of GRp58 under different physiological settings known to be associated with energy homeostasis (fasting, leptin treatment and leptin deficiency). We found that intraperitoneal administration of leptin increases whereas leptin deficiency decreases GRp58 mRNA levels. However, GRp58 expression remains unchanged after fasting, indicating that leptin actions on GRp58 are no direct sensitivity to fasting. Dissection of the molecular pathways mediating the interactions between ER stress-related factors and nutrient availability, as well as their target genes, may open a new avenue for the study of obesity and other metabolic disorders.
A method is described for calculating the approximate fractal dimension from a set of N values y sampled from a waveform between time zero and t. The waveform was subjected to a double linear transformation that maps it into a unit square.
Fundamental solution of degenerated Fokker - Planck equation is built by means of the Fourier transform method. The result is checked by direct calculation.
We calculate all point symmetries of the Fokker - Planck equation in three-dimensional Euclidean space. General expression of symmetry group action on arbitrary solution of Fokker - Planck equation is presented.
A system of ODE's is used to approximate the dynamics of two delayed coupled FitzHugh-Nagumo excitable units, and study the relevant bifurcations. It is shown that the Bautin bifurcation acts as the organizing center for the dynamics of ODE's for small time-lags.
Lecture given Thursday 22 October 1992 at a Mathematics-Computer Science Colloquium at the University of New Mexico. The lecture was videotaped; this is an edited transcript.
Braid theory is used to calcualte the topological entropy of data from the belousov-Zhabotinskii reaction, the results agree well with one-dimensional theory to the order of approximation considered.
We construct a coupled set of nonlinear reaction-diffusion equations which are exactly solvable. The model generalizes both the Burger equation and a Boltzman reaction equation recently introduced by Th. W. Ruijgrok and T. T. Wu.
An exact solution is presented for a swinging Atwood's machine. This teardrop-heart orbit is constructed using Hamilton-Jacobi theory. The example nicely illustrates the utility of the Hamilton-Jacobi method for finding solutions to nonlinear mechanical systems when more elementary techniques fail.
The Green's functions of the two and three-dimensional relativistic Aharonov-Bohm (A-B) systems are given by the path integral approach. In addition the exact radial Green's functions of the spherical A-B quantum billiard system in two and three-dimensional are obtained via the perturbation techanique of $δ$-function.
We propose a unified definition for synchronization. By example we show that the synchronization phenomena discussed in the dynamical systems literature can be described within the framework of this definition.
This brief note argues that, contrary to the claim of Ishioka and Fuchikami (chao-dyn/9902012), Landauer's principle is concerned a priori with entropy generation in computing processes. The concept of heat, in this principle, is only relevant when a connection with thermodynamics is established.