Cancer statistics, 2024
R. Siegel, Angela N Giaquinto, A. Jemal
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States and compiles the most recent data on population‐based cancer occurrence and outcomes using incidence data collected by central cancer registries (through 2020) and mortality data collected by the National Center for Health Statistics (through 2021). In 2024, 2,001,140 new cancer cases and 611,720 cancer deaths are projected to occur in the United States. Cancer mortality continued to decline through 2021, averting over 4 million deaths since 1991 because of reductions in smoking, earlier detection for some cancers, and improved treatment options in both the adjuvant and metastatic settings. However, these gains are threatened by increasing incidence for 6 of the top 10 cancers. Incidence rates increased during 2015–2019 by 0.6%–1% annually for breast, pancreas, and uterine corpus cancers and by 2%–3% annually for prostate, liver (female), kidney, and human papillomavirus‐associated oral cancers and for melanoma. Incidence rates also increased by 1%–2% annually for cervical (ages 30–44 years) and colorectal cancers (ages <55 years) in young adults. Colorectal cancer was the fourth‐leading cause of cancer death in both men and women younger than 50 years in the late‐1990s but is now first in men and second in women. Progress is also hampered by wide persistent cancer disparities; compared to White people, mortality rates are two‐fold higher for prostate, stomach and uterine corpus cancers in Black people and for liver, stomach, and kidney cancers in Native American people. Continued national progress will require increased investment in cancer prevention and access to equitable treatment, especially among American Indian and Alaska Native and Black individuals.
Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association
C. Tsao, A. Aday, Zaid I Almarzooq
et al.
Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). Methods: The American Heart Association, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing. The 2023 Statistical Update is the product of a full year’s worth of effort in 2022 by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. The American Heart Association strives to further understand and help heal health problems inflicted by structural racism, a public health crisis that can significantly damage physical and mental health and perpetuate disparities in access to health care, education, income, housing, and several other factors vital to healthy lives. This year’s edition includes additional COVID-19 (coronavirus disease 2019) publications, as well as data on the monitoring and benefits of cardiovascular health in the population, with an enhanced focus on health equity across several key domains. Results: Each of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. Conclusions: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.
AMERICAN FINANCE ASSOCIATION
2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
P. Heidenreich, B. Bozkurt, D. Aguilar
et al.
AIM The "2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure" replaces the "2013 ACCF/AHA Guideline for the Management of Heart Failure" and the "2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure." The 2022 guideline is intended to provide patient-centric recommendations for clinicians to prevent, diagnose, and manage patients with heart failure. METHODS A comprehensive literature search was conducted from May 2020 to December 2020, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from MEDLINE (PubMed), EMBASE, the Cochrane Collaboration, the Agency for Healthcare Research and Quality, and other relevant databases. Additional relevant clinical trials and research studies, published through September 2021, were also considered. This guideline was harmonized with other American Heart Association/American College of Cardiology guidelines published through December 2021. Structure: Heart failure remains a leading cause of morbidity and mortality globally. The 2022 heart failure guideline provides recommendations based on contemporary evidence for the treatment of these patients. The recommendations present an evidence-based approach to managing patients with heart failure, with the intent to improve quality of care and align with patients' interests. Many recommendations from the earlier heart failure guidelines have been updated with new evidence, and new recommendations have been created when supported by published data. Value statements are provided for certain treatments with high-quality published economic analyses.
Dynamical Systems
Christiaan Heij, André C.M. Ran, Frederik van Schagen
THIS book comes as a welcome addition to a note-worthy series of volumes—the American Mathematical Society Colloquium Publications—and it contains, with subsequent developments, the material presented in Prof. Birkhoff's Colloquium Lectures at Chicago in 1920.Dynamical Systems.By Prof. George D. Birkhoff. (American Mathematical Society Colloquium Publications, Vol. 9.) Pp. viii + 295. (New York: American Mathematical Society; Cambridge: Bowes and Bowes; Berlin: Hirschwaldsche Buchhandlung, 1927.) 3 dollars.
Version 4 of the CRU TS monthly high-resolution gridded multivariate climate dataset
I. Harris, T. Osborn, P. Jones
et al.
CRU TS (Climatic Research Unit gridded Time Series) is a widely used climate dataset on a 0.5° latitude by 0.5° longitude grid over all land domains of the world except Antarctica. It is derived by the interpolation of monthly climate anomalies from extensive networks of weather station observations. Here we describe the construction of a major new version, CRU TS v4. It is updated to span 1901–2018 by the inclusion of additional station observations, and it will be updated annually. The interpolation process has been changed to use angular-distance weighting (ADW), and the production of secondary variables has been revised to better suit this approach. This implementation of ADW provides improved traceability between each gridded value and the input observations, and allows more informative diagnostics that dataset users can utilise to assess how dataset quality might vary geographically. Measurement(s) temperature • volume of hydrological precipitation • vapour pressure • wet days • cloud cover Technology Type(s) digital curation Factor Type(s) date of observation • location of observation Sample Characteristic - Environment climate system Sample Characteristic - Location Asia • Africa • Europe • Australia • North America • South America Measurement(s) temperature • volume of hydrological precipitation • vapour pressure • wet days • cloud cover Technology Type(s) digital curation Factor Type(s) date of observation • location of observation Sample Characteristic - Environment climate system Sample Characteristic - Location Asia • Africa • Europe • Australia • North America • South America Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.11980500
3809 sitasi
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Environmental Science, Medicine
Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association
S. Virani, Á. Alonso, E. Benjamin
et al.
Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports on the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). Methods: The American Heart Association, through its Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update. The 2020 Statistical Update is the product of a full year’s worth of effort by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. This year’s edition includes data on the monitoring and benefits of cardiovascular health in the population, metrics to assess and monitor healthy diets, an enhanced focus on social determinants of health, a focus on the global burden of cardiovascular disease, and further evidence-based approaches to changing behaviors, implementation strategies, and implications of the American Heart Association’s 2020 Impact Goals. Results: Each of the 26 chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. Conclusions: The Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, healthcare administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.
COVID-19 and African Americans.
C. Yancy
Much has been published in leading medical journals about the phenomenon of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The resulting condition, coronavirus disease 2019 (COVID-19), has had a societal effect comparable only to the Spanish flu epidemic of 1918. As the flow of clinical science has better informed the contemporary narratives, more is being learned about which individuals and groups experience the most dire complications. Researchers have emphasized older age, male sex, hypertension, diabetes, obesity, concomitant cardiovascular diseases (including coronary artery disease and heart failure), and myocardial injury as important risk factors associated with worse outcomes; specifically, case-fatality rates vary over 100%.1-3 These data sourced from China and Europe have not been replicated in the US, but the US experience may nevertheless represent similarly distressing outcomes in these highest-risk phenotypes. The concerns about these observations are appropriate and the published data are indeed actionable; those who fit the highest-risk phenotypes can be advised to assiduously adhere to safe practices including hand hygiene, use of masks in public spaces, and social distancing/physical isolation.4 These measures not only are flattening the curve but are no doubt saving lives. However, a new concern has arisen: evidence of potentially egregious health care disparities is now apparent. Persons who are African American or black are contracting SARS-CoV-2 at higher rates and are more likely to die.5
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
D. Arnett, R. Blumenthal, Michelle A. Albert
et al.
Author(s): Arnett, Donna K; Blumenthal, Roger S; Albert, Michelle A; Buroker, Andrew B; Goldberger, Zachary D; Hahn, Ellen J; Himmelfarb, Cheryl D; Khera, Amit; Lloyd-Jones, Donald; McEvoy, J William; Michos, Erin D; Miedema, Michael D; Munoz, Daniel; Smith, Sidney C; Virani, Salim S; Williams, Kim A; Yeboah, Joseph; Ziaeian, Boback
Fourth universal definition of myocardial infarction (2018).
K. Thygesen, J. Alpert, A. Jaffe
et al.
Kristian Thygesen* (Denmark), Joseph S. Alpert* (USA), Allan S. Jaffe (USA), Bernard R. Chaitman (USA), Jeroen J. Bax (The Netherlands), David A. Morrow (USA), Harvey D. White* (New Zealand): the Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/ American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction
Dietary Guidelines for Americans, 2020–2025
L. Snetselaar, Janet M de Jesus, Dana M. DeSilva
et al.
The Dietary Guidelines for Americans, 2020–2025 was issued jointly by the US Departments of Agriculture and of Health and Human Services in December 2020. It is the ninth edition of the Dietary Guidelines and is the first to provide recommendations by life stage, from birth to older adulthood. The Dietary Guidelines is grounded in the current body of scientific evidence on diet and health outcomes and aims to promote health and prevent chronic diseases. The process to develop the Dietary Guidelines involved 4 steps: (1) identifying the topics and supporting scientific questions, (2) appointing a Dietary Guidelines Advisory Committee (Committee) to review current scientific evidence, (3) developing the new edition of the Dietary Guidelines, and (4) implementing the Dietary Guidelines. The 2020-2025 edition provides 4 overarching guidelines and supporting key recommendations that encourage healthy dietary patterns across the life span. The foods and beverages that people consume have a profound impact on health, and it is never too late or too early to eat healthfully.
The American College of Obstetricians and Gynecologists
Committee on Practice Bulletins—Gynecology. This Practice Bulletin was developed by the Committee on Practice Bulletins—Gynecology with the assistance of Robert L. Reid, MD. The information is designed to aid practitioners in making decisions about appropriate obstetric and gynecologic care. These guidelines should not be construed as dictating an exclusive course of treatment or procedure. Variations in practice may be warranted based on the needs of the individual patient, resources, and limitations unique to the institution or type of practice. Background
2016 Guidelines of the American Society of Mammalogists for the use of wild mammals in research and education
R. Sikes
Guidelines for use of wild mammal species in research are updated from Sikes et al. (2011). These guidelines cover current professional techniques and regulations involving the use of mammals in research and teaching; they also incorporate new resources, procedural summaries, and reporting requirements. Included are details on capturing, marking, housing, and humanely killing wild mammals. It is recommended that Institutional Animal Care and Use Committees (IACUCs), regulatory agencies, and investigators use these guidelines as a resource for protocols involving wild mammals, whether studied in the field or in captivity. These guidelines were prepared and approved by the American Society of Mammalogists (ASM), in consultation with professional veterinarians experienced in wildlife research and IACUCs, whose collective expertise provides a broad and comprehensive understanding of the biology of nondomesticated mammals. The current version of these guidelines and any subsequent modifications are available online on the Animal Care and Use Committee page of the ASM website (http://mammalogy.org/uploads/committee_files/CurrentGuidelines.pdf). Additional resources pertaining to the use of wild animals in research are available at: http://www.mammalsociety.org/committees/animal-care-and-use#tab3.
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Medicine, Biology
2015 ESC Guidelines for the Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death.
S. Priori, Carina Blomström-Lundqvist, Andrea Mazzanti
et al.
ACC : American College of Cardiology ACE : angiotensin-converting enzyme ACS : acute coronary syndrome AF : atrial fibrillation AGNES : Arrhythmia Genetics in the Netherlands AHA : American Heart Association AMIOVIRT : AMIOdarone Versus Implantable cardioverter-defibrillator:
Diabetic Neuropathy: A Position Statement by the American Diabetes Association
R. Pop-Busui, A. Boulton, E. Feldman
et al.
Diabetic neuropathies are the most prevalent chronic complications of diabetes. This heterogeneous group of conditions affects different parts of the nervous system and presents with diverse clinical manifestations. The early recognition and appropriate management of neuropathy in the patient with diabetes is important for a number of reasons: 1. Diabetic neuropathy is a diagnosis of exclusion. Nondiabetic neuropathies may be present in patients with diabetes and may be treatable by specific measures. 2. A number of treatment options exist for symptomatic diabetic neuropathy. 3. Up to 50% of diabetic peripheral neuropathies may be asymptomatic. If not recognized and if preventive foot care is not implemented, patients are at risk for injuries to their insensate feet. 4. Recognition and treatment of autonomic neuropathy may improve symptoms, reduce sequelae, and improve quality of life. Among the various forms of diabetic neuropathy, distal symmetric polyneuropathy (DSPN) and diabetic autonomic neuropathies, particularly cardiovascular autonomic neuropathy (CAN), are by far the most studied (1–4). There are several atypical forms of diabetic neuropathy as well (1–4). Patients with prediabetes may also develop neuropathies that are similar to diabetic neuropathies (5–10). Table 1 provides a comprehensive classification scheme for the diabetic neuropathies. View this table: Table 1 Classification for diabetic neuropathies Due to a lack of treatments that target the underlying nerve damage, prevention is the key component of diabetes care. Screening for symptoms and signs of diabetic neuropathy is also critical in clinical practice, as it may detect the earliest stages of neuropathy, enabling early intervention. Although screening for rarer atypical forms of diabetic neuropathy may be warranted, DSPN and autonomic neuropathy are the most common forms encountered in practice. The strongest available evidence regarding treatment pertains to these forms. This Position Statement is based on several recent technical reviews, to which the reader is referred for detailed discussion …
Neural Architectures for Named Entity Recognition
Guillaume Lample, Miguel Ballesteros, Sandeep Subramanian
et al.
Comunicacio presentada a la 2016 Conference of the North American Chapter of the Association for Computational Linguistics, celebrada a San Diego (CA, EUA) els dies 12 a 17 de juny 2016.
4272 sitasi
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Computer Science
Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.
S. Nagueh, O. Smiseth, C. Appleton
et al.
Birth as an American Rite of Passage
R. Davis-Floyd
Why do so many American women allow themselves to become enmeshed in the standardized routines of technocratic childbirth - routines that can be insensitive, unnecessary and even unhealthy? And why, in spite of the natural childbirth movement, has hospital birth become even more intensively technologized? Robbie Davis-Floyd argues that these obstetrical procedures are rituals that enact the core values of American society. Hospital birth, she says, is a rite of passage that reflects and transmits our cultural belief in the superiority of science over nature, machines over bodies, men over women, institutions over individuals. Most women hold these beliefs, and therefore choose such births. Davis-Floyd's interviews with mothers and health care professionals, interpreted from the perspective of symbolic anthropology, reveal both the trauma and the satisfaction women derive from technocratic birth. The author also explores the ritual socialization of obstetricians, showing how their beliefs and choices, too, are culturally constructed. Pointing to the advantages women can gain from technocratic birth, Davis-Floyd also calls for greater cultural and medical tolerance of the alternative beliefs and rituals of home-birthers. Only when the phenomenon of technocratic childbirth is fully understood can women's birth choices be consciously made.
U.S. Port Disruptions under Tropical Cyclones: Resilience Analysis by Harnessing Multiple-Source Dataset
Chenchen Kuai, Zihao Li, Yunlong Zhang
et al.
This study introduces the CyPort Dataset, recording disruptions to 145 U.S. principal ports and freight network from 90 tropical cyclones (2015-2023). It addresses limitations of event specific resilience studies and provides a comprehensive dataset for broader analysis. To account for excess zeros and unobserved heterogeneity in disruption outcomes, the Random Parameter Negative Binomial Lindley (RPNB Lindley) model is employed to produce more reliable resilience insights. The model demonstrates improved fit over traditional methods and uncovers variation in how features such as wind speed, storm surge height, rainfall, and distance to cyclone influence disruption outcomes across ports. This analysis reveals a tipping point at Saffir Simpson Hurricane Category 4, where disruptions escalate sharply, causing greater impacts and prolonged recovery. Regionally, ports along the Gulf of America show greatest vulnerability. Within the freight network, ports with high betweenness centrality are more resilient, while transshipment and local hubs are more fragile.
The Datafication of Care in Public Homelessness Services
Erina Seh-Young Moon, Devansh Saxena, Dipto Das
et al.
Homelessness systems in North America adopt coordinated data-driven approaches to efficiently match support services to clients based on their assessed needs and available resources. AI tools are increasingly being implemented to allocate resources, reduce costs and predict risks in this space. In this study, we conducted an ethnographic case study on the City of Toronto's homelessness system's data practices across different critical points. We show how the City's data practices offer standardized processes for client care but frontline workers also engage in heuristic decision-making in their work to navigate uncertainties, client resistance to sharing information, and resource constraints. From these findings, we show the temporality of client data which constrain the validity of predictive AI models. Additionally, we highlight how the City adopts an iterative and holistic client assessment approach which contrasts to commonly used risk assessment tools in homelessness, providing future directions to design holistic decision-making tools for homelessness.