Hasil untuk "physics.app-ph"

D. Perrin, B. Dempsey

J. Raven, F. A. Smith

W. Moolenaar, R. Tsien, P. Saag et al.

B. S. Stein, B. S. Stein, S. D. Gowda et al.

K. J. Ellis, J. Morrison

R. Naidu, N. Bolan, R. Kookana et al.

M. Chesler, K. Kaila

J. Jamieson, H. Stein, T. Demeester et al.

K. Engin, D. Leeper, J. Cater et al.

M. Chuan, G. Shu, J. C. Liu

B. Zaid, D. Saidi, A. Benzaid et al.

M. E. Parolo, M. Savini, J. M. Vallés et al.

Abstract The adsorption of tetracycline (TC) on a Patagonian montmorillonite is studied as a function of pH, ionic strength and TC concentration by using X-ray diffraction, UV–Visible spectroscopy, ATR-FTIR spectroscopy, batch experiments and adsorption modeling. X-ray diffraction reveals that TC species can intercalate into the interlayer space of montmorillonite as deduced from the change in the basal spacing from 12.6 A to 19.5 A, in the absence or presence of TC respectively. UV–Visible and ATR-FTIR spectroscopies show that the corresponding spectra of TC change upon adsorption, suggesting important montmorillonite–TC interactions in the adsorbed state. Batch experiments, on the other hand, reveal that there is an important adsorption of TC in a wide range of pH. Since at low pH (pH

T. Arnett

W. Boron

Yi Liu, Vyacheslav S. Bryantsev, M. S. Diallo et al.

T. Duffield, J. Plaizier, A. Fairfield et al.

S. Baruah, J. Dutta

A. Dhaka, V. Uzzell, A. Dubin et al.

Maintaining physiological pH is required for survival, and exposure to alkaline chemicals such as ammonia (smelling salts) elicits severe pain and inflammation through unknown mechanisms. TRPV1, the capsaicin receptor, is an integrator of noxious stimuli including heat and extracellular acidic pH. Here, we report that ammonia activates TRPV1, TRPA1 (another polymodal nocisensor), and other unknown receptor(s) expressed in sensory neurons. Ammonia and intracellular alkalization activate TRPV1 through a mechanism that involves a cytoplasmic histidine residue, not used by other TRPV1 agonists such as heat, capsaicin or low pH. Our studies show that TRPV1 detects both acidic and basic deviations from homeostatic pH.

Warisara Lertpaitoonpan, S. Ong, T. Moorman

S. Sorieul, Ph. Alfaurt, L. Daudin et al.