Hasil untuk "Miscellaneous systems and treatments"

Tejaswinee Mishra, Aarti Jagannathan, Lakshmi Nishitha Jasti

Background: Krida yoga, as a stand-alone intervention, has not been extensively researched in the field of mental health, especially for inpatients. Previous studies have been conducted on healthy populations and have included Krida yoga as the part of their overall yoga programme. Most of these yoga programs have reported improvements in various outcomes, such as stress, anxiety, physical health, and psychological wellbeing, with no negative effects, indicating that Krida yoga, along with other forms of yoga, is beneficial. In this context, the current study aimed to develop and test the feasibility of the Krida yoga group programme on stress and well-being of inpatients of the Department of Integrative Medicine, NIMHANS. Methods: A sample of 30 inpatients having neurological and psychiatric conditions participated in a 15-day, thrice-weekly, 1-h Krida yoga programme conducted by the researcher, a certified yoga trainer. Tools such as the Perceived Stress Scale-14 (PSS-14) and WHO Well-being Scale (WHO-5) were used to assess the pre- and post-effects of the Krida yoga programme on days 0 and 15. Results: Pre- and post-quantitative findings indicated a significant reduction in stress from 35.20 (5.51%) to 19.86 (3.9%) and an improvement in well-being from 9.36 (1.67%) to 15.93 (1.93%). Thematic analysis of the qualitative data collected from the inpatients supported the quantitative findings. The triangulated quantitative and qualitative findings suggested moderate to high feasibility of the Krida yoga group programme for inpatients in mental health settings. Conclusion: Based on these results, it can be concluded that the Krida yoga programme is feasible to conduct and should be tested for its effectiveness in future randomized controlled trials.

Saniye Merve Cengiz, Sevde Nihal Yongacı, Kübra Arslan Çarpar

Amaç: Gelişen teknolojiyle birlikte dijital tasarımların ve üretimlerin ortodontik tedavilerde kullanımı sonucu popülaritesi artan şeffaf plaklar, yüksek oranda tercih edilen bir tedavi seçeneği olarak karşımıza çıkmaktadır. Bu anket çalışmasında diş hekimliği fakültesinde ortodonti pratik ve teorik eğitimini alan 4. ve 5. sınıf öğrencileri ile son 2 sene içerisinde mezun olmuş diş hekimlerinin şeffaf plak tedavileri hakkındaki bilgi düzeylerinin değerlendirilmesi amaçlanmaktadır. Gereç ve Yöntemler: Çalışmaya diş hekimliği 4. ve 5. sınıf öğrencileri ile son 2 sene içerisinde mezun olmuş diş hekimleri dahil edildi. Katılımcılara şeffaf plaklar ile ilgili 25 sorudan oluşan bir anket uygulandı. Bulgular: Çalışmaya toplamda 219 birey katıldı. Katılımcıların 96’sı 4. sınıf öğrencisi, 75’i 5. sınıf öğrencisi ve 48’i 2023-2024 yıllarında mezun olmuş diş hekimlerinden oluşmaktadır. Yapılan istatistiksel analizler sonucunda pekiştirme apareyi ve tedaviyi uygulaması gereken hekim grubuna dair verilen yanıtlarda farklı yaş gruplarına göre istatistiksel olarak anlamlı farklılıklar bulunmuştur (p<0,05). Plakların takılıp çıkarılabilmesi, plaklarla uyunabilmesi, plakta beslenmeyle oluşan renklenme ve plaklarla ağız bakımına dair verilen yanıtlarda cinsiyet gruplarına göre istatistiksel olarak anlamlı farklılıklar bulunmuştur (p<0,05). Şeffaf plakların nereden/kimden duyulduğu, plaklarla uyunabilmesi, ataşmanların amacı ve uygulanması ile protetik yaklaşımlara dair verilen yanıtlarda farklı eğitim düzeylerine göre istatistiksel olarak anlamlı farklılıklar bulunmuştur (p<0,05). Sonuç: Gelişen teknolojiyle birlikte popülaritesi artan şeffaf plak tedavilerine dair bilgi düzeylerinde anlamlı farklılıklar olduğu görülmüştür. Şeffaf plak tedavilerinin etkinliğinin arttırılmasında, materyalin tanınması ve tüm özelliklerinin anlaşılabilmesi için bilgi düzeyinin arttırılması gerekmektedir.

Doğancan Çavmak

Objective: Intensive care units are one of the most complex and critical service production areas that incur high levels of resource consumption in hospitals. This study aims to analyze the cost structures of intensive care units, and to examine cost containment strategies that can be implemented in this area. Methods: The study is a systematic literature review, employing the PRISMA flow diagram. The review was carried out in two stages using the Web of Science database, focusing on the cost structures of units and cost reduction strategies. Results: The study synthesized finding from 14 papers to examine the topic. The results of the 10 studies on the cost structure indicated that the cost structures of intensive care units are mostly composed of labor, medical consumables, and equipment expenses. Among the cost control methods, quality improvement, lean management, and value streams were detected to be frequently used approaches.Conclusion: Given that intensive care units are high-cost service areas, it will be beneficial to examine them considering cost management approaches.

Lihong Diao, Xinyi Fan, Jiang Yu et al.

Objective: To elucidate the biological basis of the heart qi deficiency (HQD) pattern, an in-depth understanding of which is essential for improving clinical herbal therapy. Methods: We predicted and characterized HQD pattern genes using the new strategy, TCM-HIN2Vec, which involves heterogeneous network embedding and transcriptomic experiments. First, a heterogeneous network of traditional Chinese medicine (TCM) patterns was constructed using public databases. Next, we predicted HQD pattern genes using a heterogeneous network-embedding algorithm. We then analyzed the functional characteristics of HQD pattern genes using gene enrichment analysis and examined gene expression levels using RNA-seq. Finally, we identified TCM herbs that demonstrated enriched interactions with HQD pattern genes via herbal enrichment analysis. Results: Our TCM-HIN2Vec strategy revealed that candidate genes associated with HQD pattern were significantly enriched in energy metabolism, signal transduction pathways, and immune processes. Moreover, we found that these candidate genes were significantly differentially expressed in the transcriptional profile of mice model with heart failure with a qi deficiency pattern. Furthermore, herbal enrichment analysis identified TCM herbs that demonstrated enriched interactions with the top 10 candidate genes and could potentially serve as drug candidates for treating HQD. Conclusion: Our results suggested that TCM-HIN2Vec is capable of not only accurately identifying HQD pattern genes, but also deciphering the basis of HQD pattern. Furthermore our finding indicated that TCM-HIN2Vec may be further expanded to develop other patterns, leading to a new approach aimed at elucidating general TCM patterns and developing precision medicine.

Shuting Liu, Ranran Zhu, Chongjie Yao et al.

Background: Most clinical trials have reported significant short-term effects of traditional medicine therapies on COVID-19 patients. However, there is no clinical trial to determine the long-term effects of traditional medicine therapies on severe COVID-19 patients. Methods: A total of 128 patients with severe COVID-19, who were recruited in our previous clinical trial following hospital discharge, were monitored at months 14 and 28. This trial aims to evaluate the long-term effect of an early Qigong exercise and acupressure rehabilitation program on patients with severe COVID-19.The intervention group received qigong exercise and acupressure therapy, plus standard therapies. The control group received standard therapies.The study was a single-center, parallel, randomized, prospective follow-up study. The outcomes of the study included changes in the modified Borg dyspnea scale (MBS), the modified Medical Research Council dyspnea scale (mMRC), the patient health questionnaire-9 scale (PHQ-9), the activity of daily living (ADL), the remaining clinical symptoms and any intervention related adverse events. Results: The intervention group showed a statistically significant improvement in the mMRC scores (−0.4, 95 % CI (−0.6, 0.2), P < 0.001) and the MBS scores (−0.6, 95 % CI (−0.9, −0.3), P < 0.001) after 14 months of discharge compared with the control group. At 28 months of discharge, the intervention group, compared with the control group alone, significantly increased their MBS scores (−0.4, 95 % CI (−0.7, −0.1), P = 0.024) and a significantly decreased positive rate of dyspnea symptoms after 14 months of discharge (P < 0.05). However, ADL and PHQ-9 scores showed no significant difference between the two groups during the follow-up (P > 0.05). Conclusions: QARP had long-term sustained efficacy for dyspnea, chest tightness, and cough in patients with COVID-19, especially in young and middle-aged patients, and the effect was significant at the 14th month of follow-up. Trial registration: This trial was registered at the China Clinical Trial Registry (ChiCTR2100044572).

Simone Ota

Objetivo: Na obra, a neurocientista americana Maryanne Wolf investiga as conexões cerebrais e os desdobramentos cognitivos que acontecem durante e após a leitura de textos impressos e textos digitais. Conclusão: A diferença é tão grande que, segundo a autora, pode ser responsável pelo boom de crianças com déficit de atenção.  

Jenice Vitorino Monteiro, Lucas Manoel Oliveira Costa, Izabel Luiza Rodrigues de Sousa Viana et al.

O objetivo deste estudo é identificar, por meio de revisão integrativa da literatura, os benefícios do pré-natal no contexto preventivo das intercorrências obstétricas. Trata-se de uma revisão integrativa da literatura que utilizou a estratégia PICo (P - refere-se à paciente, população ou problema; I - intervenção estudada ou interesse; e Co - contexto). A busca dos artigos ocorreu nas bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Banco de Dados em Enfermagem (BDENF) via Biblioteca Virtual em Saúde (BVS), e Scientific Electronic Library Online (SciELO), por meio dos descritores combinados – complicações na gravidez, cuidado pré-natal e atenção primária à saúde e seus termos alternativos. Os critérios de inclusão foram artigos primários, disponíveis na íntegra, nas línguas portuguesa, inglesa e espanhola, no recorte temporal de 2018 a 2023. Excluíram-se teses, dissertações, trabalhos de conclusão de curso, estudos de revisão e pesquisas fora dos critérios supracitados. Obteve-se um total de 1.127 artigos. Após a  aplicação dos filtros, 167 artigos foram selecionados para leitura prévia de títulos e resumos e, destes, 44 foram lidos na íntegra, excluindo-se 34 por não responderem ao objetivo do estudo. A amostra final foi composta por 10 artigos. As pesquisas analisadas apontaram que as síndromes hipertensivas, diabetes gestacionais e síndromes hemorrágicas foram as principais causas de intercorrência no ciclo gravídico, além das consequências do uso de substâncias psicoativas na gestação, identificadas a partir do pré-natal. Foram percebidos benefícios do pré-natal como meio diagnóstico, profilático e educador durante a gestação, estreitando os vínculos entre as mulheres usuárias e os profissionais. Evidenciou-se que, mesmo no amparo de medidas de segurança gestacional, a morbimortalidade materna ainda persiste. O estudo reforça a importância do pré-natal para a evolução segura e planejada da gravidez, sobretudo quando há presença de doenças de base e histórico de complicações pregressas.

Minke Tang, Linglong Luo, Chi Zhang et al.

Miao is an important ethnic minority in China. Miao medicine (MM) is a pivotal of traditional Chinese medicine. It is an accumulation of the Miao people’s experience fighting against diseases for thousands of years and has been an important part of the Miao culture. The origin of MM is closely related to Miao culture, customs, and habits. MM gradually formed a traditional medical theoretical system with obvious regional characteristics, distinctive cultural characteristics, and unique efficacy. In this paper, we introduce and review the unique theoretical system of MM, including the basic theory of MM, the theory of medicine, nature, taste, and channel tropism, and the theory of entering the shelf. In addition, we summarize the development of MM to provide an overview of the theoretical characteristics and industrialisation of MM that is accessible to everyone.

Zeqi Dai, Xing Liao

Hospital-based health technology assessment (HB-HTA) is highly valuable in the application of hospital medical technology, cost control, improvement of medical quality, and protection of medical safety, and its use is increasing daily globally. However, in China, HB-HTA is still in its infancy, and it is yet to be adopted in traditional Chinese medicine (TCM). Therefore, this article introduces the application and development of HB-HTA, as well as discusses the current situation of TCM and related future development strategies to provide ideas and references for the development of HB-HTA in TCM. We conclude and recommend that all major stakeholders, including the state, health departments, and hospital leaders, support and promote the exploration and development of HB-HTA in TCM hospitals and integrative medicine hospitals. We also suggest the utilization of existing talents and introduction of other necessary talents to promote better and faster organizational development, as well as suggest the formation of a national and internationally recognized HB-HTA guidance manual and toolkit for TCM hospitals based on both the national HTA guidelines and the evaluation of TCM hospitals pilot projects. Moreover, we recommend that HB-HTA pilot study should be executed with Chinese patent medicine as the starting point to form the implementation process and framework in the TCM arena.

Hyun-Min Yoon, The Editorial Board of Journal of Pharmacopuncture

Objectives: Our study aimed to determine the attitudes of second- and final-year medical students and doctors (teaching faculty) of modern medicine towards complementary and alternative medicine (CAM) using the Complementary, Alternative, and Integrative Medicine Attitude Questionnaire (CAIMAQ). Methods : : We invited 248 second-year medical students, 245 final-year medical students, and 48 faculty members to participate in the study. The CAIMAQ consists of 30 items, divided into five categories assessing various aspects of CAM, and scored using a 7-point Likert scale. The median scores obtained were compared between groups; a p-value < 0.05 was considered statistically significant.Results : : A total of 138 medical students and faculty responded and participated in the study, of which, 24 (17.4%) were faculty, 40 (29%) were final-year medical students and 74 (53.6%) were second-year medical students. The overall attitude towards the various CAM concepts and therapies was positive. In general, the faculty were significantly less likely to consider referring patients for CAIM treatments, integrating them with conventional medicine, referring patients to alternative healthcare providers, considering the use of subtle energy fields as an ethical form of treatment, or considering CAIM treatments to be less invasive and harmful compared with conventional medicine. There was no significant difference in the attitudes of second- and final-year students. Conclusion : : The attitude of medical students and doctors towards CAM is positive, and although the medical faculty have reservations in recommending specific types of CAM therapies or integrating them with conventional care, building evidence for supporting CAM therapies in specific diseases is likely to increase its uptake among health care professionals.

Ji Hyuk Yang, Jeong A. Woo, Hyun Woo Nam et al.

Yang Yang, Liangxiao Ma, Tingli Niu et al.

Objective: To compare the effects of pulsating and static cupping on non-specific neck pain and local skin microcirculation blood perfusion, which is a pilot study. Methods: Seventy participants with non-specific neck pain were randomized to the following groups: low-frequency pulsating cupping (LF, n = 20); high-frequency pulsating cupping (HF, n = 20); static cupping (SC, n = 20), or waiting list (WL, n = 10). The LF, HF, and SC received a bilateral 10-minute cupping treatment at Jianzhongshu (SI 15). Outcomes were pain intensity (visual analog scale, VAS), functional status (Neck Disability Index, NDI), and skin blood perfusion at the SI 15, Dazhui (GV 14), and Shenzhu (GV 12) acupoint areas, measured using Laser Speckle Contrast Analysis technology. Results: Both LF and HF groups showed a significant reduction in VAS scores compared with the SC group (9.00, 95% CI 1.05–16.95, P = .027; 8.75, 95% CI 0.80–16.70, P = .031). There was no significant difference in VAS scores between the LF and HF groups (P > .05) and between NDI scores measured 3 days after intervention among the four groups (P > .05). In the SI 15 area, blood perfusion in the three treatment groups was higher than that in WL group (P < .01), and the perfusion unit (PU) of the HF pulsating group at 5 minutes after intervention was significantly higher compared with the SC group (P < .05). In the GV 14 area, blood perfusion in the two pulsating cupping groups was higher compared with the WL and SC groups after cupping (P < .05). In the GV 12 area, the PU of the LF group was higher compared with the other three groups only at the time of cup removal (P < .05). Conclusion: This study showed that pulsating cupping may have more favorable analgesic effects on non-specific neck pain compared with static cupping, which may be related to its better effect on improving the local skin blood perfusion. Keywords: Pulsating cupping, Static cupping, Non-specific neck pain, VAS, Blood perfusion

Chang-Gue Son

Nonalcoholic fatty liver disease (NAFLD) has become the common cause leading to chronic liver diseases recently. Unlikely past humankind history, NAFLD is like a new illness especially in developed countries due to decreased number of hepatic virus carriers and increased population with obesity. Among subjects with NAFLD, development of nonalcoholic steatohepatitis (NASH) is a key pathological step which determines the clinical progression. This study reports a case of a boy who has suffered from NASH for 2 years. This study aims to discuss the clinical feature, risk aspect, and treatment strategy of NASH as well as potential of traditional Korean medicine (TKM) therapies. Keywords: NAFLD, NASH, Nonalcoholic fatty liver disease, Nonalcoholic steatohepatitis, Traditional Korean medicine

Chhaya S. Godse, Prakash S. Tathed, Sameer S. Talwalkar et al.

Background: An unceasing threat of drug resistance continuously poses demand for new antimalarial drugs. A scientific assessment of traditionally used antimalarial plants through reverse pharmacology is crucial for a fast track drug discovery. An Ayurvedic plant Nyctanthes arbor-tristis Linn. – (Parijat) is being used in clinical practice and had shown antimalarial activity, with a parasite clearance in 76.6% of 120 patients, in an earlier clinical study. Objective: To further explore antimalarial potential of the plant through additional objective markers. Materials and methods: An open-labelled observational study was conducted at M.A. Podar Hospital – Ayurveda (MAPH-A) after ethics committee approval. Administration of a paste of 5 fresh leaves, thrice a day for a week was a standard practice for management of malaria at MAPH-A. Clinical activity of N. arbor-tristis was evaluated by monitoring pyrexia, parasitemia and morbidity score (MS) in twenty patients. In addition, immune and biochemical markers and organ functions were monitored for objective markers of response. Student's paired-‘t’ test was applied to assess statistical significance. Results: Ten out of 20 patients showed both fever and parasite clearance, which was confirmed by polymerase chain reaction. Remaining ten patients had persistent but decreasing parasitemia. Four of them needed chloroquine as a fail-safe procedure. Irrespective of the degree of parasitemia all the patients showed decrease in MS. There was also an increase in platelet count and normalization of plasma lactic acid. There was a good clinical tolerability and an improvement in organ function. The inflammatory cytokines showed a reduction; particularly in TNF-α within a day. Conclusions: At the given dosage, N. arbor-tristis showed disease-modifying activity; early clinical recovery with a decline of TNF-α and a gradual parasite clearance. Further studies with a standardised formulation for dose-searching and optimizing the treatment schedule are needed in a larger sample size. Clinical trial registration no: The process of trial registration had not begun when the study was conducted in 2000.

R K Mutatkar

Sasidharan K Rajesh

Sanjeev Rastogi, Priyanka Chaudhari

L. Qinghua, L. Mou

P. Crome

V. Sathyanarayana, K. Drew, S. Hardcastle et al.