SAÚDE E RESILIÊNCIA DE IDOSOS PARTICIPANTES DE PROJETO DE EXTENSÃO NA UNIVERSIDADE ABERTA DA MELHOR IDADE
Lusmara Santos Coffacci, Paulo Ramsés da Costa, Ana Beatriz Aparecida Fernandes Dantas
et al.
Introdução: O envelhecimento populacional exige a compreensão dos fatores que promovem a qualidade de vida na velhice, como a resiliência, capacidade intrínseca do indivíduo de se adaptar a situações de estresse ou trauma, preservando sua saúde e estabilidade emocional. Objetivo: Descrever as características de saúde e de resiliência de idosos participantes da Universidade Aberta da Melhor Idade (UNAMI) da Universidade Estadual de Mato Grosso do Sul (UEMS). Metodologia: Estudo transversal quantitativo, realizado com 20 idosos participantes da UNAMI/UEMS, em Dourados, Mato Grosso do Sul, Brasil. Utilizou a Escala de Resiliência adaptada por Pesce et al. (2005), constituída por 25 questões agregadas em três fatores: Fator 1. Resolução de ações e valores que dão sentido à vida; Fator 2. Agrupa itens que transmitem a ideia de independência e determinação; e o Fator 3. Indica autoconfiança e capacidade de adaptação a situações. Os dados foram analisados por estatística descritiva e analítica. Resultados: Na amostra pesquisada, houve o predomínio de mulheres (85%), pessoas brancas (65%), que não moravam sozinhas (60%), aposentadas ou pensionistas (80%). A média de resiliência foi elevada (157,05). 75% dos participantes avaliaram a saúde como "boa/muito boa" e não houve significância estatística entre os níveis da escala da resiliência e as variáveis sexo, cor da pele, arranjo familiar e autoavaliação de saúde. Conclusão: Os dados encontrados no estudo mostram que os participantes do Projeto de extensão UNAMI/UEMS possuem elevada resiliência, fato este que destaca a importância de políticas públicas voltadas à promoção do envelhecimento saudável.
Miscellaneous systems and treatments, Public aspects of medicine
O brincar no hospital e as possibilidades de participação da família: uma revisão da literatura brasileira
Mariana Oliveira Leite Silva, Maria Paula Panúncio-Pinto
Introdução: o brincar é amplamente abordado na Terapia Ocupacional. No caso de crianças hospitalizadas, terá papel central nas intervenções do terapeuta ocupacional. A criança e sua família devem ser consideradas como unidade de cuidado, considerando a centralidade dos pais para o bem estar da criança. Objetivo: identificar na literatura científica brasileira o que tem sido discutido sobre as práticas do terapeuta ocupacional relacionadas ao brincar no contexto hospitalar e considerações acerca da participação da família. Procedimentos metodológicos: revisão de mapeamento na biblioteca SciELO - Scientific Electronic Library Online e em periódicos brasileiros da área, em período aberto. Resultados: foram incluídos 31 artigos e a análise de conteúdo do material resultou em cinco eixos temáticos: (1) O brincar como fim em si mesmo; (2) O brincar enquanto recurso ou estratégia; (3) Limitações no brincar da criança hospitalizada; (4) A família assistida; (5) A família enquanto participante ativa. Conclusões: o número reduzido de trabalhos que discorrem sobre o envolvimento da família, de forma mais específica, na prática do terapeuta ocupacional, quando o tema é o brincar durante a hospitalização, desafia terapeutas ocupacionais no contexto hospitalar a repensarem suas práticas, a fim de contemplar a família como unidade de cuidado.
Miscellaneous systems and treatments
Efficacy and safety of eight-week therapy with Ashwagandha root extract in improvement of sexual health in healthy men: Findings of a prospective, randomized, double-blind, placebo-controlled study
Amit Shrenikraj Mutha, Sonali Amit Mutha, Anupama Hem Tejuja
et al.
Background: Ashwagandha, a traditional Indian Ayurvedic remedy, an adaptogen, may improve sexual dysfunction in men and women. Objective: This 8-week prospective, double-blind, randomized, placebo-controlled study evaluated the efficacy and safety of Ashwagandha Root Extract (ARE) on improving sexual health in healthy adult men. Method: A total of 100 healthy men aged 30–50 years were randomly assigned to receive ARE 300 mg twice daily (n = 50), or identical placebo (n = 50) in a 1:1 ratio for 8 weeks. Study assessments such as Satisfying Sexual Events (SSEs), the Sexual Desire Inventory (SDI-2), the International Index of Erectile Function (IIEF) score, semen parameters and the Quality of Life (QOL) were done using the SF-12 tool at baseline, week 2, week 4, and week 8. Three participants from ARE and four participants from the placebo group were excluded due to follow-up loss. The efficacy analyses were done on Per-Protocol (PP) dataset of 93, whereas safety analyses were done on all 100 participants. Results: Significant improvements were observed with ARE for semen volume (p = 0.005), sperm number (p = 0.006), sperm concentration (p = 0.007), and sperm morphology (p = 0.007). The improvement in scores was better with ARE for SDI-2 (p < 0.05), orgasm and sexual desire domains of IIEF (p < 0.05), and SF-12 (p < 0.0001). No adverse events were reported in the study. Conclusion: Ashwagandha improved the orgasmic function, sexual desire and overall sexual satisfaction with the 8-week of oral administration. It was well tolerated as it showed no significant changes in hepatic and renal parameters in blood.
Miscellaneous systems and treatments
Salutogenic Impact of Yoga on Emotional Intelligence and Perceived Stress of Medical College Students: An Interventional Study
Monica Edwin, Arun Sugumaran, Dayanidy Ganesan
et al.
Introduction:
Emotional intelligence (EI) is defined as the ability of a person to understand and respond to one’s own and others’ emotions and use this ability to guide one’s thoughts and actions. Stress is defined as a condition or feeling experienced when a person perceives that demands exceed the personal and social resources the individual is able to mobilize.
Aim:
The aim of the study was to assess the level of EI and perceived stress before and after yoga training among medical students in Puducherry.
Materials and Methods:
A nonrandomized interventional trial was conducted at the School of Yoga Therapy, Sri Balaji Vidyapeeth, Puducherry, involving 30 healthcare students (22 female and 8 male), with a mean age of 21.63 ± 1.95. Approved by the institutional ethics committee, the 6-week yoga program was held at Patanjali Yogashala on weekdays. EI and perceived stress were measured pre- and post-intervention using validated questionnaires.
Results:
The mean age of participants was 21.63 ± 1.95 years, with 73.3% females and 26.7% males. Initially, perceived stress and EI had a weak negative correlation (r = −0.24), which shifted to a weak positive correlation (r = 0.22) postyoga intervention. A significant reduction in perceived stress was noticed before and after yoga intervention. In addition, improvements in “trustworthiness” and “achievement” were significant with P = 0.049 and 0.032, respectively.
Conclusion:
This interventional trial with yoga therapy has shown a reduction in perceived stress levels and an increase in certain components of EI among medical college students in Puducherry. This study highlights the supremacy of Yoga therapy in achieving mental and psychosocial well-being.
Miscellaneous systems and treatments
Tıp Fakültesi Öğrencilerinin "Bilim, Sanat ve Tıp" Başlığı Altında Anlatılan Dersler Hakkındaki Görüşleri
Celil Atılgan, Osman Açıkgöz, Ayla Açıkgöz
et al.
Amaç: Tıp Fakültesi öğrencilerinin birinci sınıfta bilim ve meslek olarak tıpla tanışmalarının sağlanması ve insani bilimlerden uzaklaşmalarının önlenmesi amacıyla Dokuz Eylül Üniversitesi Üniversitesi Tıp Fakültesi’nde 2019-2020 eğitim-öğretim yılında "Bilim, Sanat ve Tıp" başlıklı dersler müfredata eklenmiştir. Bu çalışmanın amacı, söz konusu derslere ilişkin öğrenci görüşlerini değerlendirmek ve bu derslerin öğrencilerde kitap okuma alışkanlığına ve isteğine olan etkilerini belirlemektir. Yöntem: Dönem 2, 3, 4 ve 5 öğrencilerinden 166’sı araştırmaya katılmıştır. Hazırlanan bir anketle öğrencilerin sosyodemografik bilgileri ve dersler hakkındaki görüşleri alınmıştır. Bulgular: Öğrencilerin dersler hakkındaki olumlu görüşleri %75-90 arasında değişmekteydi. Öğrencilerin %11’i dersin kaldırılması gerektiğini, %64’ü dersin seçmeli olması gerektiğini, %48’i bu dersin ikinci sınıfta da olması gerektiğini düşünüyordu. Öğrencilerin tıp fakültesine girmeden önce ay başına düşen okudukları kitap sayısına göre anketin yapıldığı dönemde ay başına düşen okudukları kitap sayısının azaldığı saptandı (p<0,05). Sonuçlar: Öğrenciler genel olarak ders hakkında olumlu görüşe sahipti. Öğrenciler derslerin kitap okuma isteklerini artırdığını belirtmiş olmakla birlikte ilerleyen yılarda okudukları kitap sayısı azalmıştı. Öğrencilerin kitap okuma alışkanlıkları inceleyen araştırmalarla bu durumun nedenleri ortaya konabilir.
History of medicine. Medical expeditions, Miscellaneous systems and treatments
Factors associated with low back pain in ready-made garments workers in Bangladesh
Samme Akter Mithy, Shohal Hossain, Sadia Afroz
Abstract Objectives Low back pain (LBP) is an increasingly prevalent work-related condition that affects workers in manufacturing in Dhaka, Bangladesh, which often causes disability or additional problems when doing demanding physical duties. This study focused on the risk factors for LBP in the context of workers with LBP who work in the ready-made garment (RMG) factories. Methods and materials A cross-sectional study involved 385 RMG workers, all of whom were adults with ≥ 1 year of work job experience and who typically worked in a sitting position. We use surveys method for collecting data, and a standardized questionnaire covering sociodemographic, pain, work, associated effects, and activities, as well as risk factor-related variables, was used. To evaluate the associations among categorical variables and LBP, we used the chi-square test. To identify the variables that showed strong relationships with LBP, multivariable logistic regression analysis was also carried out. Results The participant’s age (mean ± SD) is 31.27 ± 6.94. One-hundred ninety-four of the 385 participants between the ages of 30–39 years (23.9%) suffered from LBP and statistically strongly significant (χ2 = 15.187, p < 0.05). BMI, employment pattern, and specific work experience are also strongly significant. Out of all risk factors, age 40 and above (OR 1.65, 95% CI 1.53–17.78), overweight (BMI > = 25 kg/m2) (OR 10.72, 95% CI 2.16–53.5), work in an awkward position, stationary position for ling time, working beyond physical ability, incorrectly using body mechanics, repeated twisting and bending, continuously longtime sitting, and using ergonomically improper tools were found to be significantly associated with LBP. Conclusion The point prevalence of LBP among RMG workers is 41.6%. Only male gender is associated with the presence of LBP. This study showed that working in an awkward position, stationary position for a long time, incorrectly using body mechanics, repeated twisting, and bending had significant associations with LBP. Training programs that instruct proper weight-bearing skills should be encouraged by factories. The occurrence of LBP must also be reduced by regularly performing screening activities to detect it, with a special focus on married people, overweight or obese, and older-aged people.
Miscellaneous systems and treatments
Effectiveness and optimal dosage of physiotherapy interventions for Bell palsy: a case study
Himani Kaushik, Avi Choudhary, Pooja Sethi
Abstract Background Bell palsy is a sudden facial nerve paralysis that affects many individuals annually. It significantly impacts patients and their families, leading to a reduced quality of life if left untreated. The International Classification of Functioning, Disability, and Health (ICF) framework focuses on outcome measures, functional limitations, and overall quality of life of the patients. Early diagnosis is crucial for effective management of the condition. In order to standardize clinical practice and contribute to recommendations of certain interventions, this paper focuses on the optimal dosage of physiotherapy intervention for Bell palsy patients, which includes exercise therapy and electrotherapy. Case presentation An Indian 33-year-old male visited our physiotherapy department 15 days after being diagnosed with right-sided Bell palsy with unknown aetiology. His chief complaints were right-eye dryness, facial pain, drooping of the face, and difficulty performing facial activities. The outcome measures are the strength duration curve (SD curve), House-Brackmann grading, manual muscle testing, and visual analogue scale (VAS) scale. The physiotherapy intervention includes two primary components: electrotherapy and exercise therapy. Conclusion The Kabat rehabilitation technique, along with nerve stimulation and an active exercise regimen, is significantly effective in treating Bell palsy, and the outcome measures show significant improvement with optimal therapy dosage.
Miscellaneous systems and treatments
Acupuncture for overactive bladder in adults: Study protocol for a randomized controlled trial
Fengqin Cao, Diyuan Ma, Yueying Chen
et al.
Background: Overactive bladder (OAB) is a prevalent condition that substantially degrades patient quality of life. Acupuncture is recognized as an effective therapeutic approach for various urological diseases. However, there is limited evidence validating the effectiveness and safety of acupuncture for OABs. Objective: To assess the therapeutic efficacy of acupuncture for OAB and to investigate the potential mechanisms by analyzing its effects on relevant urinary biomarkers. Methods: This is a randomized, participants and outcome assessors blinded, sham acupuncture controlled trial. A total of 110 patients with OABs will be randomly divided in a 1:1 ratio between the acupuncture and sham acupuncture groups. Participants in the acupuncture group will undergo 30-min authentic acupuncture, while their counterparts in the sham acupuncture group will undergo sham acupuncture needling non-acupoints superficially three times weekly for a duration of 8 weeks. The two co-primary outcomes will be the change in the mean number of micturitions per 24 h from baseline to the end of the 8-week treatment and 20-week follow-up. The secondary outcomes will encompass the change in Overactive Bladder Symptom Score, Overactive Bladder Questionnaire Short Form, and average 24 h values of urgency, daytime micturition, nocturia, and mean volume voided per micturition from baseline to weeks 8 and 20. Urinary nerve growth factor, brain-derived neurotrophic factor, and monocyte chemoattractant protein-1 levels will be measured at baseline and week 8. Adverse events will also be documented. Discussion: The results of this trial will provide evidence for the effectiveness and safety of acupuncture in the management of OAB.
Miscellaneous systems and treatments
EDUCAÇÃO PERMANENTE EM SAÚDE PARA OS TÉCNICOS E AUXILIARES DE ENFERMAGEM QUE ATUAM EM SALA DE VACINAS
Vittória Zarpelão de Matos, Mariangela Kraemer Lenz Ziede
Introdução: Sala de vacinas é um setor da Atenção Primária à Saúde (APS) destinado à aplicação de imunobiológicos, conforme o Calendário Nacional de Vacinação. A qualificação permanente dos profissionais que atuam neste espaço permite assegurar a confiança ao usuário e reduzir possíveis erros. Objetivo: Planejar, desenvolver, aplicar e avaliar ações de Educação Permanente em Saúde (EPS) para técnicos e auxiliares de Enfermagem no âmbito da sala de vacinas. Metodologia: Estudo qualitativo, do tipo pesquisa-ação, cujos participantes foram técnicos e auxiliares de Enfermagem que atuavam em serviço da APS de Porto Alegre, Rio Grande do Sul, Brasil (n=31). Ações de EPS foram realizadas em três encontros, com intervalo de 30 dias e duração de, aproximadamente, duas horas. As informações registradas dos relatos dos participantes em cada encontro foram analisadas pela análise de conteúdo. Resultados: Foram identificadas fragilidades no cotidiano do trabalho na sala de vacinas envolvendo a comunicação entre os profissionais, a qualidade dos materiais, a dificuldade de manusear os sistemas de informações, a quantidade de pessoas na sala de vacinas, a dificuldade de usuários que residiam fora do território acessarem o serviço para a vacinação e a falta de higiene adequada do local. Os equívocos mais comuns cometidos pelos profissionais foram os erros de registros e erros associados às idades limites das vacinas. A EPS ocasionou mudanças organizacionais, na comunicação interna e no fluxo de higienização. Houve uma percepção positiva da EPS pelos profissionais participantes. Conclusão: A EPS desencadeou a mobilização e o interesse dos técnicos e auxiliares de Enfermagem para o desenvolvimento permanente desta prática educativa, contemplando não só temas relacionados à vacinação, mas também assuntos pertinentes ao trabalho da equipe de Enfermagem na APS.
Miscellaneous systems and treatments, Public aspects of medicine
TESTE DE ALFABETIZAÇÃO CIENTÍFICA
Viviani Epifanio Machado Ferreira, Cristiano Corrêa Ferreira
Os jogos educacionais têm-se tornado uma ferramenta importante no contexto educacional e de ampla aceitação e domínio para a atual geração de estudantes. No processo de ensino e de aprendizagem, esses jogos precisam de um notório engajamento dos usuários. Nesse contexto, este artigo apresenta um relato de experiência que mostra o processo de desenvolvimento de um game educacional, elaborado na plataforma do software Construct 2, e que foi denominado de Scientist Avenger. O jogo teve o propósito de reproduzir em sua estrutura o Teste de Alfabetização Científica Simplificado (TACB-S), desenvolvido por Vizzoto e Mackedanz. Vale destacar que a ação teve início durante a pandemia de COVID-19, que levou as Instituições de Ensino a suspenderem suas atividades presenciais, bem como, modificou o comportamento social da sociedade. Naquele momento, a gamificação emergiu como uma metodologia ativa que possuía familiaridade com os estudantes de diferentes faixas etárias. Metodologicamente, o jogo foi planejado para percorrer quatro (4) fases e, no futuro, será aplicado em estudantes do Ensino Médio de escolas do interior do estado do Rio Grande do Sul. Espera-se que o game educacional desenvolvido se torne mais uma possibilidade do uso das tecnologias digitais no contexto escolar e que possa estimular trabalhos futuros a fim de tornar o jogo aplicável a qualquer nível da educação ou grupos de indivíduos.
Miscellaneous systems and treatments, Public aspects of medicine
TESTE DE ALFABETIZAÇÃO CIENTÍFICA
Viviani Epifanio Machado Ferreira, Cristiano Corrêa Ferreira
Os jogos educacionais têm-se tornado uma ferramenta importante no contexto educacional e de ampla aceitação e domínio para a atual geração de estudantes. No processo de ensino e de aprendizagem, esses jogos precisam de um notório engajamento dos usuários. Nesse contexto, este artigo apresenta um relato de experiência que mostra o processo de desenvolvimento de um game educacional, elaborado na plataforma do software Construct 2, e que foi denominado de Scientist Avenger. O jogo teve o propósito de reproduzir em sua estrutura o Teste de Alfabetização Científica Simplificado (TACB-S), desenvolvido por Vizzoto e Mackedanz. Vale destacar que a ação teve início durante a pandemia de COVID-19, que levou as Instituições de Ensino a suspenderem suas atividades presenciais, bem como, modificou o comportamento social da sociedade. Naquele momento, a gamificação emergiu como uma metodologia ativa que possuía familiaridade com os estudantes de diferentes faixas etárias. Metodologicamente, o jogo foi planejado para percorrer quatro (4) fases e, no futuro, será aplicado em estudantes do Ensino Médio de escolas do interior do estado do Rio Grande do Sul. Espera-se que o game educacional desenvolvido se torne mais uma possibilidade do uso das tecnologias digitais no contexto escolar e que possa estimular trabalhos futuros a fim de tornar o jogo aplicável a qualquer nível da educação ou grupos de indivíduos.
Miscellaneous systems and treatments, Public aspects of medicine
Effectiveness of face-to-face physiotherapy training and education for women who are undergoing elective caesarean section: a randomized controlled trial
Kalani Weerasinghe, Mohamed Rishard, Subhani Brabaharan
et al.
Abstract Background Caesarean Section (CS) is associated with numerous post-operative problems. The current literature reveals that physiotherapy interventions such as pelvic floor rehabilitation and post-surgical rehabilitation enable enhanced recovery in the post-operative period. The purpose of this study was to investigate the effectiveness of face-to-face physiotherapy training and education prior to elective CS in improving post-operative outcomes. Methods A single blind parallel randomized controlled study was carried out at De Soysa Hospital for Women (DSHW), Colombo. Fifty-four women who were to undergo elective CS were recruited to the study. The women in the intervention group (n = 27) received face-to-face physiotherapy training and education; the control group (n = 27) received only the standard nursing care. Outcome measures such as perception of post-operative pain, dosage of additional analgesics required, pain upon returning to functional activities and lengths of hospital stay were collected. Results were analyzed using IBM SPSS 20 using descriptive statistics and independent samples t-test. Results Mean post-operative pain score (control group; 4.2±0.46 vs. intervention group; 1.7±0.7) and doses of additional analgesics required were significantly higher in the control group than that of the intervention group. Pain upon returning to functional activities decreased significantly within 2 days in both groups, and values were lower in the intervention group. The intervention group showed a shorter hospital stay than the control group (control group;3.9 ± 0.3 vs. intervention group;3.00 ± 0.0) (p < 0.05). Conclusions Face-to-face physiotherapy training and education prior to elective CS appears to be a promising intervention to improve the post-operative outcomes by reducing post-operative pain, doses of additional analgesics required, pain upon returning to functional activities and lengths of hospital stay. Trial registration SLCTR/2019/029-APPL/2019/028 ; Registered on 6th of September 2019.
Miscellaneous systems and treatments
In vivo anticancer effects of Momordica charantia seed fat on hepatocellular carcinoma in a rat model
K.N.K. Ranasinghe, A.D. Premarathna, T.A.N. Mahakapuge
et al.
Background: Momordica charantia or bitter melon is a well-known vegetable with a number of therapeutic actions in Ayurvedic medicine. Alpha-eleostearic acid, a conjugated trienoic fatty acid present in bitter melon is proven to have anticancer properties. Crude seed oil from local bitter melon varieties could be an effective and economical anticancer therapy. Objective(s): The study was conducted to evaluate the anticancer effect of the crude oil from the seeds of Matale green variety of bitter melon on a hepatocellular carcinoma-induced rat model. Materials and methods: Hepatocellular carcinoma (HCC) was experimentally induced in Wistar rats. Crude seed oil of Matale green bitter melon (MGBM) was supplemented to one treatment group in concurrence with carcinoma induction and to another treatment group after the development of carcinoma. After 168 days, gross morphological, histopathological, biochemical, hematological and gene-expression analysis of treated and control groups were performed. Results: Oral supplementation of MGBM seed oil showed a statistically significant reduction (p < 0.05) in the average number, diameter and area of hepatic dysplastic nodules and a reduction in the size of histopathological neoplastic lesions in both treatment groups compared to the non-treated control group. The expression of tumor suppressor gene p53 and anti-apoptotic gene Bcl-2 were significantly increased while the expression of apoptotic gene caspase 3 was significantly reduced in the treatment group when MGBM supplementation was in concurrence with carcinogenesis (p < 0.05). Conclusion: Crude seed oil from the MGBM has anticancer effects against experimentally induced HCC in Wistar rats, specially when supplemented in concurrence with carcinoma induction.
Miscellaneous systems and treatments
Extracting needling component from acupuncture treatment: ZOMBIE acupuncture
Kyungmo Park, Minsung Kang
Miscellaneous systems and treatments
Impact of sham acupuncture information disclosure in participant information leaflets on participant blinding and trial outcomes: a randomised controlled trial
JIyoon Won, Heejung Bang, Hyangsook Lee
Miscellaneous systems and treatments
PRÁTICAS DE SAÚDE BUCAL E O SISTEMA DE ENSINO SUPERIOR PORTUGUÊS: NEXOS E DESCONEXÕES
Graciela Soares Fonsêca, Carlos Botazzo, Simone Rennó Junqueira
et al.
Existe, dentro do Sistema Nacional de Saúde (SNS) português, um programa direcionado à promoção, prevenção e controle das doenças bucais operacionalizado por Higienistas Orais e Médicos Dentistas. O objetivo do trabalho é refletir sobre a organização das práticas em saúde bucal, inseridas no SNS, estabelecendo conexões com o sistema de ensino superior de Portugal. Trata-se de uma revisão narrativa da literatura, cuja busca foi norteada pela combinação de diferentes descritores, principalmente, nas bases de dados MEDLINE e SciELO (Scientific Eletronic Library Online), realizada no segundo semestre de 2015, incluídos no estudo quando traziam algum elemento que pudesse contribuir na reflexão da relação investigada. Para maior compreensão do objeto de estudo, a análise foi complementada por documentos do SNS, disponíveis nos sites dos Ministérios da Saúde e da Educação de Portugal. Os resultados revelaram que as necessidades de saúde bucal da população convivem com estratégias que, além de não conseguirem responder ao conjunto das demandas, reforçam a mercantilização da saúde bucal. Ao compreender o modelo formador de profissionais que atuam no âmbito da saúde bucal e perceber que o contato com a comunidade é fortemente concretizado por meio dos Higienistas Orais, justifica-se a grande quantidade de práticas preventivistas desenvolvidas no país. Mesmo com a participação dos médicos dentistas no Programa de Saúde Oral, identificam-se lacunas que dificultam o estabelecimento de ações efetivas para gerar melhorias nos níveis de saúde bucal. É necessário aprofundar o debate sobre as questões aqui apresentadas, integrando as ações do sistema de ensino superior às práticas de saúde bucal, de modo a revelar elementos propulsores de mudança e melhoria na saúde bucal dos portugueses.
Palavras-chave: Saúde Bucal. Portugal. Sistemas de Saúde. Ensino Superior.
Miscellaneous systems and treatments, Public aspects of medicine
Alleviating exercise-induced muscular stress using neat and processed bee pollen: oxidative markers, mitochondrial enzymes, and myostatin expression in rats
Sameer Ketkar, Atul Rathore, Amit Kandhare
et al.
Background: The current study was designed to investigate the influence of monofloral Indian mustard bee pollen (MIMBP) and processed monofloral Indian mustard bee pollen (PMIMBP) supplementation on chronic swimming exercise-induced oxidative stress implications in the gastrocnemius muscle of Wistar rats.
Methods: MIMBP was processed with an edible lipid-surfactant mixture (Captex 355:Tween 80) to increase the extraction of polyphenols and flavonoid aglycones as analyzed by UV spectroscopy and high performance liquid chromatography-photo diode array. Wistar rats in different groups were fed with MIMBP or PMIMBP supplements at a dose of 100 mg/kg, 200 mg/kg and 300 mg/kg individually, while being subjected to chronic swimming exercise for 4 weeks (5 d/wk). Various biochemical [superoxide dismutase (SOD), glutathione (GSH), malonaldehyde (MDA), nitric oxide (NO), and total protein content], mitochondrial (Complex I, II, III, and IV enzyme activity), and molecular (myostatin mRNA expression) parameters were monitored in the gastrocnemius muscle of each group.
Results: Administration of both MIMBP (300 mg/kg) and PMIMBP (100 mg/kg, 200 mg/kg, and 300 mg/kg) wielded an antioxidant effect by significantly improving SOD, GSH, MDA, NO, and total protein levels. Further MIMBP (300 mg/kg) and PMIMBP (200 mg/kg and 300 mg/kg) significantly improved impaired mitochondrial Complex I, II, III, and IV enzyme activity. Significant down-regulation of myostatin mRNA expression by MIMBP (300 mg/kg) and PMIMBP (200 mg/kg and 300 mg/kg) indicates a muscle protectant role in oxidative stress conditions.
Conclusion: The study establishes the antioxidant, mitochondrial upregulatory, and myostatin inhibitory effects of both MIMBP and PMIMBP in exercise-induced oxidative stress conditions, suggesting their usefulness in effective management of exercise-induced muscular stress. Further, processing of MIMBP with an edible lipid-surfactant mixture was found to improve the therapeutic efficiency of pollen.
Miscellaneous systems and treatments
Single-dose Toxicity of Water-soluble Ginseng Pharmacopuncture Injected Intramuscularly in Rats
Junsang Yu, Seungho Sun, Kwangho Lee
et al.
Medicine, Miscellaneous systems and treatments
Towards TRAIL to silencing of SMURF and NEDD4: FLIP is flopped -
A. Farooqi, S. Fayyaz, Shahzad Bhatti
et al.
An independent water system with maximized wastewater reuse for non-potable purposes - Model case for future urban development
Xudong Wang, Rong-zhong Chen, Yaqian Liu
et al.
4 sitasi
en
Environmental Science