Hasil untuk "physics.soc-ph"

L. C. R. Aaij, B. Adeva, M. Adinolfi et al.

The LHCb detector is a forward spectrometer at the Large Hadron Collider (LHC) at CERN. The experiment is designed for precision measurements of CP violation and rare decays of beauty and charm hadrons. In this paper the performance of the various LHCb sub-detectors and the trigger system are described, using data taken from 2010 to 2012. It is shown that the design criteria of the experiment have been met. The excellent performance of the detector has allowed the LHCb collaboration to publish a wide range of physics results, demonstrating LHCb's unique role, both as a heavy flavour experiment and as a general purpose detector in the forward region.

T. A. C. G. Aad, E. Abat, B. Abbott et al.

A detailed study is presented of the expected performance of the ATLAS detector. The reconstruction of tracks, leptons, photons, missing energy and jets is investigated, together with the performance of b-tagging and the trigger. The physics potential for a variety of interesting physics processes, within the Standard Model and beyond, is examined. The study comprises a series of notes based on simulations of the detector and physics processes, with particular emphasis given to the data expected from the first years of operation of the LHC at CERN.

A. Bellacosa, T. Chan, N. N. Ahmed et al.

M. Falasca, S. Logan, V. Lehto et al.

K. Christensen, Jesse T. Myers, J. Swanson

E. Gillies, J. Fréchet

J. Whalen, Chi Chang, G. Clayton et al.

Sang-Eun Oh, Steven W. van Ginkel, B. Logan

Z. Meng, A. Wolberg, D. Monroe et al.

Mingchun Zhao, M. Liu, G. Song et al.

J. Hachem, D. Crumrine, J. Fluhr et al.

Both exposure of stratum corneum to neutral pH buffers and blockade of acidification mechanisms disturb cutaneous permeability barrier homeostasis and stratum corneum integrity/cohesion, but these approaches all introduce potentially confounding variables. To study the consequences of stratum corneum neutralization, independent of hydration, we applied two chemically unrelated superbases, 1,1,3,3-tetramethylguanidine or 1,8-diazabicyclo [5,4,0] undec-7-ene, in propylene glycol:ethanol (7:3) to hairless mouse skin and assessed whether discrete pH changes alone regulate cutaneous permeability barrier function and stratum corneum integrity/cohesion, as well as the responsible mechanisms. Both 1,1,3,3-tetramethylguanidine and 1,8-diazabicyclo [5,4,0] undec-7-ene applications increased skin surface pH in parallel with abnormalities in both barrier homeostasis and stratum corneum integrity/cohesion. The latter was attributable to rapid activation (<20 min) of serine proteases, assessed by in situ zymography, followed by serine-protease-mediated degradation of corneodesmosomes. Western blotting revealed degradation of desmoglein 1, a key corneodesmosome structural protein, in parallel with loss of corneodesmosomes. Coapplication of serine protease inhibitors with the superbase normalized stratum corneum integrity/cohesion. The superbases also delayed permeability barrier recovery, attributable to decreased beta-glucocerebrosidase activity, assessed zymographically, resulting in a lipid-processing defect on electron microscopy. These studies demonstrate unequivocally that stratum corneum neutralization alone provokes stratum corneum functional abnormalities, including aberrant permeability barrier homeostasis and decreased stratum corneum integrity/cohesion, as well as the mechanisms responsible for these abnormalities.

E. Ajandouz, L. Tchiakpe, F. Oré et al.

S. Sassman, Linda S. Lee

G. Rudenko, L. Henry, K. Henderson et al.

M. Qiao, D. L. Fletcher, D. P. Smith et al.

The relationship between broiler breast meat color and pH, moisture content, water-holding capacity (WHC), and emulsification capacity (EC) was investigated. In each of three replicate trials, fillets were collected from three different commercial processing plants according to breast meat lightness (L*) values as follows: lighter than normal (light, L* > 53), normal (48 < L* < 53), and darker than normal (dark, L* < 46). Color values of lightness (L*), redness (a*), and yellowness (b*) were measured at 0 and 24 h after collection. Fillets were then ground and homogenized prior to determining color, pH, moisture, WHC, and EC of the ground meat. There was a significant difference among the three color groups (light, normal, and dark) in L*, a*, pH, WHC, and EC. The L* values of whole raw breast fillets had significant negative correlation coefficients with ground meat EC (-0.9237), pH (-0.9610), and a* (-0.6540). Emulsification capacity had significant positive correlations with pH (0.9572) and water-holding capacity (0.7080). WHC had significant correlations with a* (0.8143), moisture (-0.7647), and pH (0.7963). Lighter-than-normal meat was associated with low pH, high moisture, low EC, and low WHC. These results indicate that wide differences in raw breast meat color exist and that these differences may be used by poultry further processors as an indicator of fillets with altered functional properties.

John T Mongan, D. Case, J. A. McCammon

N. Nelson, R. Mikkelsen, D. Hesterberg

A. Park, L. Fan

A. Pol, K. Heijmans, H. Harhangi et al.

Paul Paroutis, N. Touret, S. Grinstein