Hasil untuk "physics.ed-ph"

L. C. R. Aaij, B. Adeva, M. Adinolfi et al.

The LHCb detector is a forward spectrometer at the Large Hadron Collider (LHC) at CERN. The experiment is designed for precision measurements of CP violation and rare decays of beauty and charm hadrons. In this paper the performance of the various LHCb sub-detectors and the trigger system are described, using data taken from 2010 to 2012. It is shown that the design criteria of the experiment have been met. The excellent performance of the detector has allowed the LHCb collaboration to publish a wide range of physics results, demonstrating LHCb's unique role, both as a heavy flavour experiment and as a general purpose detector in the forward region.

H. Fang, Hong Liu

J. Llopis, J. Mccaffery, Atsushi Miyawaki et al.

K. Emerson, R. Russo, R. Lund et al.

L. Gerweck, K. Seetharaman

M. Koivusalo, Christopher M. Welch, H. Hayashi et al.

Inhibitors of Na+/H+ exchange proteins block macropinocytosis by lowering the pH near the plasma membrane, which in turn inhibits actin remodeling by Rho family GTPases.

S. Schael, R. Barate, R. Brunelière et al.

O. Husson

BackgroundOxidation-reduction and acid–base reactions are essential for the maintenance of all living organisms. However, redox potential (Eh) has received little attention in agronomy, unlike pH, which is regarded as a master variable. Agronomists are probably depriving themselves of a key factor in crop and soil science which could be a useful integrative tool.ScopeThis paper reviews the existing literature on Eh in various disciplines connected to agronomy, whether associated or not with pH, and then integrates this knowledge within a composite framework.ConclusionsThis transdisciplinary review offers evidence that Eh and pH are respectively and jointly major drivers of soil/plant/microorganism systems. Information on the roles of Eh and pH in plant and microorganism physiology and in soil genesis converges to form an operational framework for further studies of soil/plant/microorganism functioning. This framework is based on the hypothesis that plants physiologically function within a specific internal Eh-pH range and that, along with microorganisms, they alter Eh and pH in the rhizosphere to ensure homeostasis at the cell level. This new perspective could help in bridging several disciplines related to agronomy, and across micro and macro-scales. It should help to improve cropping systems design and management, in conventional, organic, and conservation agriculture.

Chunyi Sun, C. Qin, Xinlong Wang et al.

M. McCulloch, J. Falter, J. Trotter et al.

M. Kühl, Y. Cohen, T. Dalsgaard et al.

Xinpeng Ma, Yiguang Wang, Tian Zhao et al.

pH is an important physiological parameter that plays a critical role in cellular and tissue homeostasis. Conventional small molecular pH sensors (e.g., fluorescein, Lysosensor) are limited by broad pH response and restricted fluorescent emissions. Previously, we reported the development of ultra-pH-sensitive (UPS) nanoprobes with sharp pH response using fluorophores with small Stokes shifts (50-fold between on and off states). The UPS library provides a useful toolkit to study pH regulation in many pathophysiological indications (e.g., cancer, lysosome catabolism) as well as establishing tumor-activatable systems for cancer imaging and drug delivery.

Elena Aznar, M. Marcos, R. Martínez‐Máñez et al.

F. J. Heredia, E. Francia-Aricha, J. Rivas-Gonzalo et al.

C. Dicko, F. Vollrath, J. Kenney

K. Young, P. M. Foegeding

T. Parkin, A. Sexstone, J. Tiedje

Louise J Edwards, David A. Williams, David K. Gardner

Edward W. HICKEYt, I. Hirshfield

W. Vonau, U. Guth