A new class of soft energy harvesters, known as magnetoelastic generators (MEGs), has been made possible by the giant magnetoelastic effect. These generators can efficiently convert low-frequency and irregular mechanical stimuli into electricity. This review summarises the mechanism of magnetoelastic coupling and recent progress in soft magnetic composites, flexible architectures, and bio-inspired designs. We focus on the application of MEGs in some specific fields, such as wearable electronics, self-powered sensing, acoustic energy harvesting, and blue energy systems, demonstrating their unique advantages over traditional harvesters. Despite the rapid advances, there are still some challenges remain in improving energy density, such as how to improve energy density, maintain long-term stability, realize large-scale manufacturing, and do a good job in system-level power management. Finally, we point out the important opportunities and future directions, hoping to help develop and integrate the next generation magnetoelastic energy system.
We review how unitarity and stationarity in the Schwinger-Keldysh formalism naturally lead to a (quantum) generalized fluctuation-dissipation relation (gFDR) that works beyond thermal equilibrium. Non-Gaussian loop corrections are also presented. Additionally, we illustrate the application of this gFDR in various scenarios related to quantum Brownian motion and the generalized Langevin equation.
Abstract Myotonic dystrophy (DM) is caused by expansions of C(C)TG repeats in the non-coding regions of the DMPK and CNBP genes, and DM patients often suffer from sudden cardiac death due to lethal conduction block or arrhythmia. Specific molecular changes that underlie DM cardiac pathology have been linked to repeat-associated depletion of Muscleblind-like (MBNL) 1 and 2 proteins and upregulation of CUGBP, Elav-like family member 1 (CELF1). Hypothesis solely targeting MBNL1 or CELF1 pathways that could address all the consequences of repeat expansion in heart remained inconclusive, particularly when the direct cause of mortality and results of transcriptome analyses remained undetermined in Mbnl compound knockout (KO) mice with cardiac phenotypes. Here, we develop Myh6-Cre double KO (DKO) (Mbnl1−/−; Mbnl2cond/cond; Myh6-Cre+/−) mice to eliminate Mbnl1/2 in cardiomyocytes and observe spontaneous lethal cardiac events under no anesthesia. RNA sequencing recapitulates DM heart spliceopathy and shows gene expression changes that were previously undescribed in DM heart studies. Notably, immunoblotting reveals a nearly 6-fold increase of Calsequestrin 1 and 50% reduction of epidermal growth factor proteins. Our findings demonstrate that complete ablation of MBNL1/2 in cardiomyocytes is essential for generating sudden death due to lethal cardiac rhythms and reveal potential mechanisms for DM heart pathogenesis.
Abstract Bishop, C, Berney, J, Lake, J, Loturco, I, Blagrove, R, Turner, A, and Read, P. Bilateral deficit during jumping tasks: relationship with speed and change of direction speed performance. J Strength Cond Res 35(7): 1833–1840, 2021—Research to date has investigated the phenomenon of the bilateral deficit (BLD); however, limited research exists on its association with measures of athletic performance. The purpose of this study was to investigate the magnitude of the BLD and examine its relationship with linear speed and change of direction speed (CODS) performance. Eighteen physically active and healthy university students performed double- and single-leg countermovement jumps (CMJs), drop jumps (DJs), and standing broad jumps (SBJs) to calculate the BLD across jump tasks. Subjects also performed 10- and 30-m sprints and a 505 CODS test, which were correlated with all BLD metrics. Results showed varying levels of BLD across CMJ metrics (jump height, peak force, eccentric impulse, concentric impulse, and peak power), DJ metrics (ground contact time and flight time), and the SBJ (distance). However, a bilateral facilitation was shown for jump height and reactive strength index during the DJ test. The main findings of this study were that: (a) a larger BLD in CMJ height related to a faster 505 COD (left leg) (r = −0.48; p = 0.04), 505 COD (right leg) (r = −0.53; p = 0.02), and COD deficit (right leg) (r = −0.59; p = 0.01), (b) a larger BLD in CMJ concentric impulse related to faster 505 COD (left leg) (r = −0.51; p = 0.03), 505 COD (right leg) (r = −0.64, p = 0.01), and COD deficit (right leg) (r = −0.60; p = 0.01), and (c) a larger BLD in DJ flight time related to a faster 505 COD (left leg) (r = −0.48; p = 0.04). These results suggest that a larger BLD is associated with faster CODS performance, but not linear speed. This highlights the individual nature of the BLD and may support the notion of developing movement competency on one limb for enhanced CODS performance.
Abstract Abbott, W, Brickley, G, Smeeton, NJ, and Mills, S. Individualizing acceleration in English Premier League academy soccer players. J Strength Cond Res 32(12): 3512–3519, 2018—Global thresholds are typically used to band acceleration dependent on intensity. However, global thresholds do not account for variation in individual capacities, failing to quantify true intensity of acceleration. Previous research has investigated discrepancies in high-speed distance produced using global and individual speed thresholds, not yet investigated for acceleration. The current aim was to investigate discrepancies between global and individual thresholds when quantifying acceleration tasks. Acceleration data were recorded for 31 professional soccer players, using 10-Hz global positioning systems devices. Distances traveled performing low-, moderate-, and high-intensity acceleration were calculated for athletes using global and individual thresholds. Global acceleration thresholds for low-, moderate-, and high-intensity acceleration were classified as 1–2, 2–3, and >3 m·s−2, respectively, with individual thresholds classified as 25–50%, 50–75%, and >75% of maximum acceleration, respectively. Athletes were grouped low (LO), medium (ME), or high (HI) maximum accelerative capacity, determined using 3 maximal 40-m linear sprints. Two-way mixed-design analyses of variance were used to analyze differences in acceleration distances produced between analysis methods and athlete groups. No significant differences were identified between analysis methods for LO. For ME, no significant differences were demonstrated for low intensity. Moderate- and high-intensity acceleration distances were significantly higher for global compared with individual analysis method (p < 0.01). For HI, significantly higher acceleration distances were produced for all acceleration intensities using global thresholds (p < 0.01). Significant differences identified between analysis methods suggest practitioners must apply caution when using global thresholds. Global thresholds do not account for individual capacities and may provide an inaccurate representation of relative intensity of acceleration tasks.
We investigate the spatial structure of dense square-shoulder fluids. To this end we derive analytical perturbative solutions of the Ornstein-Zernike equation in the low- and high-temperature limits as expansions around the known hard sphere solutions. We then discuss the suitability of perturbative approaches in relation to the Ornstein-Zernike equation.
Using high-contrast imaging with the SPHERE instrument at the Very Large Telescope (VLT), we report the first images of a cold brown dwarf companion to the exoplanet host star HD 4113A. The brown dwarf HD 4113C is part of a complex dynamical system consisting of a giant planet, a stellar host, and a known wide M-dwarf companion. Its separation of 535 ± 3 mas and H-band contrast of 13.35 ± 0.10 mag correspond to a projected separation of 22 AU and an isochronal mass estimate of 36 ± 5 MJ based on COND models. The companion shows strong methane absorption, and through fitting an atmosphere model, we estimate a surface gravity of logg = 5 and an effective temperature of ~500–600 K. A comparison of its spectrum with observed T dwarfs indicates a late-T spectral type, with a T9 object providing the best match. By combining the observed astrometry from the imaging data with 27 years of radial velocities, we use orbital fitting to constrain its orbital and physical parameters, as well as update those of the planet HD 4113A b, discovered by previous radial velocity measurements. The data suggest a dynamical mass of 66−4+5 MJ and moderate eccentricity of 0.44−0.07+0.08 for the brown dwarf. This mass estimate appears to contradict the isochronal estimate and that of objects with similar temperatures, which may be caused by the newly detected object being an unresolved binary brown dwarf system or the presence of an additional object in the system. Through dynamical simulations, we show that the planet may undergo strong Lidov-Kozai cycles, raising the possibility that it formed on a quasi-circular orbit and gained its currently observed high eccentricity (e ~ 0.9) through interactions with the brown dwarf. Follow-up observations combining radial velocities, direct imaging, and Gaia astrometry will be crucial to precisely constrain the dynamical mass of the brown dwarf and allow for an in-depth comparison with evolutionary and atmosphere models.