DOAJ Open Access 2025

Effects of different types of milk consumption on type 2 diabetes and the mediating effect of AA: A Mendelian randomization study of East Asian populations

Qing-Ao Xiao Lin Chen Xiao-Long Li Qiang Han Hai-Tao Li +1 lainnya

Abstrak

ABSTRACT: There is currently a lack of research examining the association between the consumption of different dairy products and type 2 diabetes (T2D) in East Asian populations. To address this gap, the present study employs Mendelian randomization to investigate the potential effects of 3 different types of milk consumption (including whole milk, semi-skim milk, and skim milk) on the risk of developing T2D. The results indicate that both whole milk and skim milk are associated with an increased risk of T2D (whole milk: odds ratio [OR] = 1.022, 95% CI: 1.001–1.044; skim milk: OR = 1.023, 95% CI: 1.007–1.039). Mediation analysis revealed that asparagine acts as a mediator between skim milk consumption and T2D, with a mediation effect of 0.003 (95% CI: 0.000 to 0.008), accounting for 14.269% of the total effect.

Topik & Kata Kunci

Dairy processing. Dairy products Dairying

Penulis (6)

Qing-Ao Xiao

Lin Chen

Xiao-Long Li

Qiang Han

Hai-Tao Li

Xiao-Ling Zhang

Format Sitasi

APA MLA BibTeX

Xiao, Q., Chen, L., Li, X., Han, Q., Li, H., Zhang, X. (2025). Effects of different types of milk consumption on type 2 diabetes and the mediating effect of AA: A Mendelian randomization study of East Asian populations. https://doi.org/10.3168/jds.2024-26017

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Informasi Jurnal

Tahun Terbit: 2025
Sumber Database: DOAJ
DOI: 10.3168/jds.2024-26017
Akses: Open Access ✓