Alignment interactions drive structural transitions in biological tissues
Abstrak
Experimental evidence shows that there is a feedback between cell shape and cell motion. How this feedback impacts the collective behavior of dense cell monolayers remains an open question. We investigate the effect of a feedback that tends to align the cell crawling direction with cell elongation in a biological tissue model. We find that the alignment interaction promotes nematic patterns in the fluid phase that eventually undergo a non-equilibrium phase transition into a quasi-hexagonal solid. Meanwhile, highly asymmetric cells do not undergo the liquid-to-solid transition for any value of the alignment coupling. In this regime, the dynamics of cell centers and shape fluctuation show features typical of glassy systems.
Topik & Kata Kunci
Penulis (6)
Matteo Paoluzzi
Luca Angelani
Giorgio Gosti
M Cristina Marchetti
Ignacio Pagonabarraga
Giancarlo Ruocco
Akses Cepat
- Tahun Terbit
- 2021
- Bahasa
- en
- Sumber Database
- arXiv
- Akses
- Open Access ✓