arXiv
Open Access
2013
Viscoelastic Properties of Vascular Endothelial Cells Exposed to Stretch
Kathryn Osterday
Thomas Chew
Phillip Loury
Jason Haga
Manuel Gomez-Gonzalez
+2 lainnya
Abstrak
In this paper, we study how cytoskeletal remodeling is correlated to changes in subcellular microrheology. We analyze the changes in the magnitude and directionality of the shear and elastic moduli of bovine aortic endothelial cells (BAECs) exposed to cyclical, uniaxial stretch. We find that, when stretched, BAECs stiffen and align their softest direction of mechanical polarization perpendicular to stretch. We hypothesize that the response of VECs to stretch acts to minimize intracellular strain in response to stress.
Topik & Kata Kunci
Penulis (7)
K
Kathryn Osterday
T
Thomas Chew
P
Phillip Loury
J
Jason Haga
M
Manuel Gomez-Gonzalez
J
Juan C. del Alamo
S
Shu Chien
Akses Cepat
Informasi Jurnal
- Tahun Terbit
- 2013
- Bahasa
- en
- Sumber Database
- arXiv
- Akses
- Open Access ✓