Hasil untuk "History of Germany"

Alfredo Moreno-Egea, Carlos Moreno-Latorre, Alfredo Moreno-Latorre

Background: The history of radical hernia repair involves a period of intense surgical activity, influenced by factors of the time such as social development, hygiene, anesthesia, and antisepsis. Subcutaneous surgery, the initial option designed to avoid infections and peritonitis, was modified after the introduction of antisepsis, eventually leading to dissection surgery. Objective: We aim to analyze the publications from the period of radical hernia cures using current methodology, verifying when and how the transition occurred from subcutaneous surgery to dissection surgery. Methods: A literature review of the databases PubMed, LILACS, Cochrane Library, “Google” and university libraries is conducted. The following keywords were used: “anatomy and surgery”. A critical analysis of the known literature about this historical topic is carried out. Results: Under-vision dissection surgery, through incision of the aponeurosis of the external oblique muscle, began in England by Durham in 1866, almost 20 years before it was performed in France by Lucas-Championnière in 1885. Recurrences decreased after the introduction of the principle of closing the walls of the inguinal canal (Wood, 1860). The surgeon–anatomist Wood should be considered the first specialist in abdominal wall surgery, due to his extensive contributions from the pre-antiseptic era. The evolution of the radical cure of hernias was made possible by combining the knowledge of several countries: England, Germany, and Italy. Conclusions: Dissection surgery was initiated in England, Germany, and Italy, not in France. The influence of the French literature on the history of hernias is evident, to the detriment of the contributions of surgeons from other countries.

Jakub Fusiak, Andreas Wolkenstein, Verena S. Hoffmann

BackgroundPatient preferences are a critical component of shared decision-making (SDM), particularly when choosing between treatment options with differing risks and outcomes. Many methods exist to elicit these preferences, but their complexity, usability, and acceptance vary.ObjectiveWe aim to gain insight into the acceptance, effort and preferences of participants regarding five different methods of preference assessment. Additionally, we investigate the influence of health status, experiences within the health system and of demographic factors on the results.MethodsWe conducted a cross-sectional online survey including five preference elicitation Methods: best-worst scaling, direct weighting, PAPRIKA (Potentially All Pairwise Rankings of all Possible Alternatives), time trade-off, and standard gamble. The questionnaire was distributed via academic and patient advocacy mailing lists, reaching both healthy individuals and those with acute or chronic illnesses. Participants rated each method using six standardized statements on a 5-point Likert scale. Additional items assessed general acceptance of algorithm-assisted preference assessments and the clarity of the questionnaire.ResultsOf 258 initiated questionnaires, 123 (48%) were completed and included in the analysis. Participants were diverse in age, gender, and health status, but predominantly highly educated and digitally literate. Across all measures, the PAPRIKA method received the highest ratings for clarity, usability, and perceived ability to express preferences. Simpler methods (best-worst scaling, direct weighting) were rated as less useful for capturing nuanced preferences, while abstract utility-based methods (standard gamble, time trade-off) were seen as cognitively demanding. Subgroup analyses showed minimal variation across demographic groups. Most participants (82%) could imagine using at least one of the presented methods in real clinical settings, but also emphasized the importance of physician involvement in interpreting results.ConclusionThe interactive PAPRIKA method best balanced cognitive demand and expressiveness and was preferred by most participants. Structured methods for preference elicitation may enhance SDM when integrated into clinical workflows and supported by healthcare professionals. Further research is needed to evaluate their use in real-world decisions and among more diverse patient populations.

Alice Knutas, Angela Adamo, Alex Pedrini et al.

We present JWST NIRCam observations of the emerging young star clusters (eYSCs) detected in the nearby spiral galaxy M83. The NIRcam mosaic encompasses the nuclear starburst, the bar, and the inner spiral arms. The eYSCs, detected in Pa α and Br α maps, have been largely missed in previous optical campaigns of young star clusters (YSCs). We distinguish between eYSCI, if they also have compact 3.3 μ m polycyclic aromatic hydrocarbon (PAH) emission associated with them, and eYSCII, if they only appear as compact Pa α emitters. We find that the variations in the 3.3 μ m PAH feature are consistent with an evolutionary sequence where eYSCI evolve into eYSCII and then optical YSCs. This sequence is clear in the F300M​​​​​​−F335M (tracing the excess in the 3.3 μ m PAH feature) and the F115W−F187N (tracing the excess in Pa α ) colors, which become increasingly bluer as clusters emerge. The central starburst stands out as the region where the most massive eYSCs are currently forming in the galaxy. We estimate that only about 20% of eYSCs will remain detectable as compact YSCs. Combining eYSCs and YSCs (≤10 Myr), we recover an average clearing timescale of 6 Myr in which clusters transition from embedded to fully exposed. We see evidence of shorter emergence timescales (∼5 Myr) for more massive (>5 × 10 ^3 M _⊙ ) clusters, while star clusters of ∼10 ^3 M _⊙ about 7 Myr. We estimate that eYSCs remain associated with the 3.3 μ m PAH emission for 3–4 Myr. Larger samples of eYSC and YSC populations will provide stronger statistics to further test environmental and cluster mass dependencies on the emergence timescale.

Tesfu Fekensa Tujuba, Roman V. Yakovlev, Aidas Saldaitis et al.

African golden-spotted lappet moths from the genera Haplopacha Aurivillius, 1905 and Dasychirinula Hering, 1926 are reviewed. Antennae, heads and legs are investigated in addition to the traditional comparison of habitus, genitalia, and distribution areas. Two new genera are established and four new species are described as a result: Eudoumbia gen. n. with the type-species Eudoumbia thorogood sp. n. from Angola, Namibia, and Botswana; Auripluvia gen. n. with the type species Auripluvia sophia sp. n. from Ethiopia; Haplopacha mason sp. n. from Tanzania; and Dasychirinula julia sp. n. from Ethiopia. One species is reattributed to the new genus as Eudoumbia ndoumoi (Dupont, Simonsen & Zilli, 2016) stat. n. One new synonymy is established for two Tanzanian species: Dasychirinula chrysogramma Hering, 1926 = Haplopacha lunata Dupont, Simonsen & Zilli, 2016 syn. n.; and one potential synonymy is remarked between Haplopacha tangani Dupont, Simonsen & Zilli, 2016 from Tanzania and Malawi and Haplopacha riftensis Dupont, Simonsen & Zilli, 2016 from Malawi. Photos of the related material stored in the main collections of Ditsong National Museum of Natural History (Pretoria, RSA) and Natural History Museum of Zimbabwe (Bulawayo, Zimbabwe) are showed.

Ben Thuy, Mats E. Eriksson, Manfred Kutscher et al.

Due to the fragility of the ophiuroid (brittle star) skeleton, the bulk of the group’s fossil record consists of dissociated ossicles preserved as microfossils. In spite of their great potential as basis for taxonomic and phylogenetic studies, however, ophiuroid ossicles from the Paleozoic have received very little attention so far. Here, we provide an exhaustive taxonomic assessment of such fossils retrieved from sieving residues from the Silurian of Gotland, Sweden. This material was used in a previous study to describe two key taxa that allowed constraining the origin of the extant ophiuroid clade. The remaining taxa belonging to that same lineage are described in the present paper. The evidence at hand suggests that the stem of the extant ophiuroid clade was formed by two genera, Ophiopetagno and Ophiolofsson gen. nov., including six and five species, respectively, and spanning at least the upper Llandovery through upper Ludlow. We conclude that Ophiopetagno and Ophiolofsson represent sister genera that coexisted through most of the Silurian in the shallow tropical seas of Gotland. They underwent repeated body size reductions in correlation with environmental perturbations, with Ophiopetagno paicei eventually giving rise to Muldaster haakei; the first member of the living Ophiuroidea. Herein, we also introduce two new clades, Ankhurida clade nov. and Ophiovalida clade nov., and the following eight new species: Ophiolofsson joelmciveri gen. et sp. nov., O. obituary gen. et sp. nov., O. immolation gen. et sp. nov., O. archspire gen. et sp. nov., O. hendersonorum gen. et sp. nov., Ophiopetagno bonzo sp. nov., O. kansas sp. nov., O. doro sp. nov.; and two probably new species in open nomenclature: Ophiopetagno sp. 1, and Ophiopetagno sp. 2.

Luis A. Anchordoqui, Ignatios Antoniadis, Dieter Lüst

Over the last few years, low- and high-redshift observations set off tensions in the measurement of the present-day expansion rate H0 and in the determination of the amplitude of the matter clustering in the late Universe (parameterized by S8). It was recently noted that both these tensions can be resolved if the cosmological constant parametrizing the dark energy content switches its sign at a critical redshift zc∼2. However, the anti-de Sitter (AdS) swampland conjecture suggests that the postulated switch in sign of the cosmological constant at zero temperature seems unlikely because the AdS vacua are an infinite distance apart from de Sitter (dS) vacua in moduli space. We provide an explanation for the required AdS → dS crossover transition in the vacuum energy using the Casimir forces of fields inhabiting the bulk. We then use entropy arguments to claim that any AdS → dS transition between metastable vacua must be accompanied by a reduction of the species scale where gravity becomes strong. We provide a few examples supporting this AdS → dS uplift conjecture.

Nele Hellweg, Heide Glaesmer, Barbara Stelzl-Marx et al.

Background: During the post-World War II occupation of Austria, approximately 20,000–30,000 ‘children born of war’ (CBOW), also called occupation children were born through intimate contacts between Austrian women and occupation soldiers. Research on other CBOW populations indicates that CBOW mostly grow up under difficult conditions, sometimes with strong long-term mental health consequences.Objective: To examine whether comparable psychosocial consequences can be found in Austrian occupation children (AOC), a first quantitative study was carried out.Method: Child maltreatment, post-traumatic stress disorder, depression and somatization, and general life satisfaction were assessed in a sample of 98 AOC using self-report instruments. Results were compared to a sample of German occupation children (GOC; N = 146).Results: High prevalence of above threshold full (10.2%) and partial (14.3%) PTSD, somatic (16.3%) and depressive (11.1%) symptomatology were found in AOC. They were at high risk of child maltreatment (e.g. emotional abuse: 53.6%), which was associated with current symptomatology. Notably, AOC tended to report high levels of general life satisfaction. No differences were found between GOC and AOC.Conclusions: Findings highlight the complex and long-term effects of developmental conditions and childhood maltreatment on mental health of CBOW, even decades later. Findings of high life satisfaction provide evidence of resilience and maturation processes across the lifespan.

Jan Štembera

Helmut Miiller, Kari Friedrich Krieger, Hanna Vollrath: Dějiny Německa. Přeloženo z německého originálu Deutsche Geschichte in Schlaglichtern. Nakladatelství Lidové noviny, Praha 1995, 590 stran, ISBN 80-7106-125-5.

Ludo Block

ABSTRACT This article presents the findings of exploratory research into the origins of OSINT for which it discusses three case studies from, respectively, the United States, Germany and the Netherlands. Many authors writing on open source intelligence assume that the first OSINT practices emerged at the eve of the Second World War with the establishment of the BBC Monitoring Services and the Foreign Broadcast Monitoring Service. Building on existing studies, which are supplemented with original archive research, this article demonstrates that OSINT has a much longer and richer history. Methodical efforts to collect and exploit information from publicly available sources to fulfil intelligence requirements are documented as early as halfway the 19th century in the United States and early 20th century in Europe.

N. I. Shilo

Despite serious attention to the issues of war crimes and crimes against humanity, committed on an unprecedented scale in concentration camps in Nazi Germany, the problem of medical experiments on prisoners appears to be one of the least-studied in modern Russian historiography. Moreover, no special attention was paid to testing chemical weapons on humans. The aim of this work is to review the history of the development and testing of chemical warfare agents (CWA) in Germany in 1933–1945. During the First World War, Germany was one of the leading countries in the sphere of military chemistry in the world. After the Versailles treaty this potential was largely lost as a result of the restrictions. After the National Socialist German Workers' Party (NSDAP) came to power, Germany not only restored, but also increased its military power and achieved a qualitative superiority over its opponents in the field of chemical weapons. The tests of CWA, as well as the study of the effectiveness of the means and protocols for the treatment of the lesions caused by CWA, were carried out both by the military structures of the Wehrmacht and the SS, and by civilian research and academic institutions. Experiments on prisoners were carried out in the concentration camps of Dachau, Ravensbrück, Auschwitz-Birkenau, Buchenwald, Sachsenhausen, Natzweiler-Struthof, Neuengamme, etc. Basically, the damaging effects of sulfur mustard and phosgene was investigated. In Auschwitz-Birkenau «a study of the action of various chemical preparations was carried out on the orders of German firms». After the war several SS doctors, who performed involuntary experiments on humans, were convicted by military tribunals for war crimes and crimes against humanity. Seven doctors were sentenced to death and executed on June 2, 1948, at the prison for war criminals in Landsberg, Bavaria. As a result of the Nuremberg trials, the Nuremberg Code was drawn up. It was the first international document that introduced ethical standards for scientists engaged in experiments on humans. It consisted of 10 principles, including the necessity of voluntary informed consent of the patient for the participation in medical experiments after providing him with full information about the nature, duration and purpose of the experiment; on the methods of its implementation; about all the perceived inconveniences and dangers associated with the experiment, and, finally, the possible consequences for the physical or mental health of the subject, which may arise as a result of his participation in the experiment.

Samik Bhattacharya, Franziska Gröne, Felix Przesdzink et al.

Successful plant establishment in a particular environment depends on the root architecture of the seedlings and the extent of edaphic resource utilization. However, diverse habitats often pose a predicament on the suitability of the fundamental root structure of a species that evolved over a long period. We hypothesized that the plasticity in the genetically controlled root architecture in variable habitats provides an adaptive advantage to worldwide-distributed wild radish (Raphanus raphanistrum, Rr) over its close relative (R. pugioniformis, Rp) that remained endemic to the East Mediterranean region. To test the hypothesis, we performed a reciprocal comparative analysis between the two species, growing in a common garden experiment on their native soils (Hamra/Sandy for Rr, Terra Rossa for Rp) and complementary controlled experiments mimicking the major soil compositions. Additionally, we analyzed the root growth kinetics via semi-automated digital profiling and compared the architecture between Rr and Rp. In both experiments, the primary roots of Rr were significantly longer, developed fewer lateral roots, and showed slower growth kinetics than Rp. Multivariate analyses of seven significant root architecture variables revealed that Rr could successfully adapt to different surrogate growth conditions by only modulating their main root length and number of lateral roots. In contrast, Rp needs to modify several other root parameters, which are very resource-intensive, to grow on non-native soil. Altogether the findings suggest an evo-devo adaptive advantage for Rr as it can potentially establish in various habitats with the minimal tweak of key root parameters, hence allocating resources for other developmental requirements.

Emmanuel Hourcade

K. D. Kotelnikov

The documents of the League of Nations archive concerning the history of a unique emigrant institution — the Russian Ambulatory in Berlin are introduced into scientific circulation in the article. It is reported that for at least 17 years (since 1920), the clinic had pro-vided free assistance to the poor. The annual reports and correspondence of the clinic make it possible not only to assess the scale of the activities of the philanthropists of Russian Berlin and their humanitarian significance, but also to analyze information about the social and demographic processes in the emigrant community in the 1920s—1930s. It is noted that from 1920 to 1934 the clinic received 171,955 patients (more than one and a half thousand people a year, of all ages and nationalities). Information is given that doctors treated a wide range of diseases: cardiovascular, nervous, venereal, respiratory and digestive system, urogenital system, eye and ear, the consequences of injuries and trauma. It has been established that the outpatient clinic distributed free medicines, food, and basic necessities since the early 1930s and provided lunches and places in the Salvation Army dormitory for the homeless. The statistics of the clinic are presented with data on the ethnic composition of Russian Berlin (the most representative of the known ones), the aging of emigration in Germany, and the low birth rate in the 1930s and the spread of poverty associated with the Great Depression.

Ramakrishnan S, Janssens W, Burgel PR et al.

Sanjay Ramakrishnan,1– 3 Wim Janssens,4 Pierre-Regis Burgel,5 Marco Contoli,6 Frits ME Franssen,7 Neil J Greening,8 Timm Greulich,9 Iwein Gyselinck,4 Andreas Halner,1 Arturo Huerta,10 Rebecca L Morgan,11 Jennifer K Quint,12 Lowie EGW Vanfleteren,13 Kristina Vermeersch,4 Henrik Watz,14 Mona Bafadhel1 1Respiratory Medicine Unit, Nuffield Department of Medicine - Experimental Medicine, University of Oxford, Oxford, UK; 2 National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), University of Oxford, Oxford, UK; 3School of Medical and Health Sciences, Edith Cowan University, Perth, Australia; 4Department of Respiratory Diseases, UZ Leuven, Research Group BREATHE, KU Leuven, Leuven, Belgium; 5Faculty of Medicine, University of Paris and INSERM 1016 Institut Cochin, Cochin Hospital, Assistance Publique Hôpitaux de Paris, Paris, France; 6Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy; 7Department of Respiratory Medicine, Maastricht University Medical Center, Maastricht, Netherlands; 8Department of Respiratory Sciences, NIHR Leicester Biomedical Research Centre (Respiratory), Glenfield Hospital, Leicester, UK; 9Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Centre Giessen and Marburg, Philipps University, Member of the German Centre for Lung Research (DZL), Marburg, Germany; 10Pulmonary and Critical Care Division, Clinica Sagrada Familia, IDIBAPS August Pi i Sunyer Biomedical Research Institute, Barcelona, Spain; 11Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; 12National Heart & Lung Institute, Imperial College, London, UK; 13COPD Center, Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Department of Internal Medicine and Clinical Nutrition at Institute of Medicine, SU Sahlgrenska, Göteborg, Sweden; 14Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Grosshansdorf, GermanyCorrespondence: Mona BafadhelRespiratory Medicine Unit, Nuffield Department of Medicine Experimental Medicine, University of Oxford, Oxford, UKTel +44 1865 612898Email mona.bafadhel@ndm.ox.ac.ukBackground: Despite hospitalization for exacerbation being a high-risk event for morbidity and mortality, there is little consensus globally regarding the assessment and management of hospitalised exacerbations of COPD. We aimed to establish a consensus list of symptoms, physiological measures, clinical scores, patient questionnaires and investigations to be obtained at time of hospitalised COPD exacerbation and follow-up.Methods: A modified Delphi online survey with pre-defined consensus of importance, feasibility and frequency of measures at hospitalisation and follow-up of a COPD exacerbation was undertaken.Findings: A total of 25 COPD experts from 18 countries contributed to all 3 rounds of the survey. Experts agreed that a detailed history and examination were needed. Experts also agreed on which treatments are needed and how soon these should be delivered. Experts recommended that a full blood count, renal function, C-reactive protein and cardiac blood biomarkers (BNP and troponin) should be measured within 4 hours of admission and that the modified Medical Research Council dyspnoea scale (mMRC) and COPD assessment test (CAT) should be performed at time of exacerbation and follow-up. Experts encouraged COPD clinicians to strongly consider discussing palliative care, if indicated, at time of hospitalisation.Interpretation: This Europe-wide consensus document is the first attempt to standardise the assessment and care of patients hospitalised for COPD exacerbations. This should be regarded as the starting point to build knowledge and evidence on patients hospitalised for COPD exacerbations.Keywords: COPD, disease exacerbation, hospitalisation, patient care, consensus development, expert opinion

Robert N. Spengler, Michael Petraglia, Michael Petraglia et al.

Megafaunal extinctions are recurring events that cause evolutionary ripples, as cascades of secondary extinctions and shifting selective pressures reshape ecosystems. Megafaunal browsers and grazers are major ecosystem engineers, they: keep woody vegetation suppressed; are nitrogen cyclers; and serve as seed dispersers. Most angiosperms possess sets of physiological traits that allow for the fixation of mutualisms with megafauna; some of these traits appear to serve as exaptation (preadaptation) features for farming. As an easily recognized example, fleshy fruits are, an exaptation to agriculture, as they evolved to recruit a non-human disperser. We hypothesize that the traits of rapid annual growth, self-compatibility, heavy investment in reproduction, high plasticity (wide reaction norms), and rapid evolvability were part of an adaptive syndrome for megafaunal seed dispersal. We review the evolutionary importance that megafauna had for crop and weed progenitors and discuss possible ramifications of their extinction on: (1) seed dispersal; (2) population dynamics; and (3) habitat loss. Humans replaced some of the ecological services that had been lost as a result of late Quaternary extinctions and drove rapid evolutionary change resulting in domestication.

Walda-Mandel, Stephanie

Ghostnet art is an art movement of Aboriginal and Torres Strait Islander people that has been gaining enthusiastic followers worldwide in recent years, not only because of its impressive artistic design, but equally because of the artists’ message behind the artworks. The ghostnet sculptures, made mainly by members of two Australian Indigenous communities in Erub and Pormpuraaw are constructed from old fishing nets. For the artists, it is both an expression of their environmental activism to protect the oceans and their close connection with their natural environment. Their close relationship to the land and sea is reflected in the artworks, which also create a connection to their history, cultural heritage, identity, and their totems. Their works are based on their myths, their land and their culture. In 2018, the Übersee-Museum Bremen (eng. Overseas Museum Bremen) presented these impressive artworks for the first time in Germany in a small special exhibition, the realization and background of which will be discussed in this article

W. O. van der Knaap, J. V. van Leeuwen, L. Fahse et al.

Jasmin Schlax, Claus Jünger, Manfred E. Beutel et al.

Abstract Background Socioeconomic status (SES) has a strong association with depression or physical and mental health in general. However, as SES is a multifaceted construct these associations are not easy to explain. Further, there are several indicators and many studies only investigating two or less indicators at the same time. Therefore, this study aims to analyze the cross-sectional and longitudinal association of three defined SES dimensions (education, occupational position and household net-income) with the occurrence of elevated symptoms of depression relative to the impact of important covariates. Methods The study included observational data from 12,484 participants of the Gutenberg Health Study. The outcome was “elevated depressive symptoms” as defined by Patient Health Questionnaire (PHQ-2) ≥ 2 at the 2.5-year follow-up. Regression coefficients were adjusted for baseline covariates (age, sex, partnership, depression, anxiety, medical history of depressive or anxiety disorder and major medical diseases (MMD)) in addition to SES sum score and the three single indicators. We further examined interaction terms of the SES with sex, partnership and major medical diseases. We analyzed the sample stratified by elevated depressive symptoms at baseline, as we expected different trajectories in both subgroups. Results SES, education and household net-income were lower in the group of persons with PHQ-2 ≥ 2 at baseline, and they predicted the occurrence of PHQ-2 ≥ 2 at 2.5 year follow-up in the group of persons without elevated depressive symptoms at baseline after multivariable adjustment (SES: Odds Ratio (OR) 0.96, 0.95–0.98, p <  0.0001; education: OR 0.96, 0.93–0.99, p = 0.036; household net-income: OR 0.96, 0.92–0.99, p = 0.046) but not in the group of persons with elevated depressive symptoms at baseline. Further, we found that the impact of major medical diseases on the development of elevated depressive symptoms was buffered by high income. In addition, living in a partnership buffered the impact of a low occupational position. Conclusions Regarding the SES, the dimensions education and household net-income seem to play the most important role for socioeconomic inequalities in persons in Mid-West Germany with depressive symptoms. Trial registration Reference no. 837.020.07; original vote: 22.3.2007, latest update: 20.10.2015