Hasil untuk "Hazardous substances and their disposal"

Yuequn Chen, Kusheng Wu, Wenlong Huang

Bisphenol A (BPA) is an endocrine-disrupting chemical known for its developmental toxicity. However, the impact of BPA on early embryonic development, particularly during zygotic genome activation (ZGA), remains underexplored. In this study, zebrafish embryos at 3.5 and 4.5 hours post-fertilization (hpf) were collected after 7-day parental exposure to 1.0 µM BPA for transcriptome sequencing. Transcriptomic data underwent differential gene expression functional enrichment and gene set enrichment analyses. Public single-cell transcriptome atlases of zebrafish embryos at different developmental stages (3.3, 4, and 4.8 hpf) were obtained to build signature matrices for digital cell type sorting of the bulk transcriptome using the CIBERSORTx algorithm. Results indicated that parental BPA exposure resulted in muted gene expression response, disturbed energy metabolism profile, and increased pro-inflammatory signatures during ZGA. Digital cell type deconvolution revealed altered cell composition, including deeper multilayer and enveloping layer cells and fewer margin cells. Furthermore, reductions in neural progenitor and heart primordium lineages, alongside expansions in primordial germ and mesendodermal lineages, potentially contribute to later-stage developmental abnormalities. This study elucidates the embryotoxic effects of BPA during the ZGA period, shedding light on the developmental perturbations from early-life exposure to this ubiquitous environmental contaminant.

Шаповалова, О.В., Петрова, А.А., Степанов, А.В. et al.

В статье рассмотрены требования к метану как топливу для жидкостных ракетных двигателей, сформированные по результатам анализа нормативной базы, оценки влияния примесей на криогенные и теплофизические характеристики топлива, а также исследования свойств топливной смеси при сгорании. Показано, что обеспечение высокой чистоты сжиженного природного газа является ключевым условием надежной работы систем подачи и регенеративного охлаждения, а также устойчивости процессов горения. На основе проведенного анализа предложены рекомендуемый состав ракетного топлива и допустимые диапазоны концентраций примесей.

Петрова, С.Ю., Камлюк, С.Н., Гомолко, Т.Н.

В работе представлены оригинальные данные токсикологических исследований, выполненных экспериментальным и расчетным методами, по определению опасных свойств адъюванта на основе лаурет-4-фосфата, применяемого в аграрном секторе Республики Беларусь совместно с пестицидами химического синтеза. Также в работе отражены сведения по классификации опасностей изученной химической продукции для здоровья человека, полученные в результате применения двух различных методов – расчетного и экспериментального, для оценки по параметрам острой внутрижелудочной токсичности и острой токсичности при нанесении на кожу, оценки по параметрам аллергоопасности. Одним из основных критериев при выборе подхода для проведения токсикологических исследований химической продукции служит полнота имеющихся сведений об опасных свойствах ее компонентов (токсикологический профиль). Применение в комплексных токсикологических исследованиях химической продукции сочетанного подхода (с использованием экспериментального и расчетного методов установления классов опасности) не только позволяет получить наиболее полную и всестороннюю оценку препаратов по опасным для здоровья человека свойствам, но и обеспечивает гармонизацию научно-прикладной исследовательской деятельности с руководящими принципами биоэтической концепции «трех R».

Raja Saha, Sangita Maiti Dutta

Molluscs are significant aquatic organisms, which serve as bioindicator species. They are crucial for maintaining ecological balance as secondary consumers. Molluscs are threatened by pesticides such as pyrethroid insecticides. Pyrethroids are increasingly utilized to control insects in agriculture and gardening. It contaminates aquatic bodies through rainwater runoff and drainage-sewage systems. The current review will focus on the issue of increasing pyrethroid use and its biological effects on molluscs. Due to their highly lipophilic nature, pyrethroids pose a significant risk to these organisms by affecting their metabolites, producing reactive oxygen species, and influencing neurotransmitter actions. The threats to the molluscs and eventually to the concerned aquatic ecosystem warrant significant discussion and attention.

Kai Yang, Guoqiang qin, RuoYong Jia et al.

Chlorophenols (CPs) are persistent organic pollutants (POPs) widely detected in the natural environment. Sulfotransferases are a group of crucial phase II metabolic enzyme involved in the metabolism of endogenous and exogenous substances. This research aims to identify the metabolite and characterize the specific isoforms involved in the sulfonation of each CP. Recombinant enzyme assays and chemical inhibitors were used to characterize the primary SULT isoforms involved in the sulfonation of each CP. Our findings indicated that mono-sulfonate was identified in each incubation system. SULT1A1 predominated the sulfonation of monochlorophenol (MCP), SULT1A1, SULT1B1, and SULT1E1 emerged as the pivotal SULT isoforms mediating the sulfonation of 2,4-dichlorophenol (2,4-DCP), trichlorophenol (2,3,4-TCP), 2,4,6-trichlorophenol (2,4,6-TCP), and 3,4,5-trichlorophenol (3,4,5-TCP). Additionally, sulfonation of 2,4,5-trichlorophenol (2,4,5-TCP), 2,3,4,5-tetrachlorophenol (2,3,4,5-TECP), and 2,3,4,6-tetrachlorophenol (2,3,4,6-TECP) were primarily catalyzed by SULT1B1. Furthermore, SULT1B1 and SULT2A1 were the major isoforms involved in the sulfonation of 2,3,5,6-tetrachlorophenol (2,3,5,6-TECP) and pentachlorophenol (PCP). These results provide important insights into the metabolic elimination and toxicity of CPs from a novel perspective.

Madhu Surana, Dhruti Sundar Pattanayak, V.K. Singh et al.

Graphitic carbon nitride (g-C3N4) has garnered significant attention due to its low cost, ease of preparation, high chemical stability, and non-toxicity. Nevertheless, pristine g-C3N4 faces challenges in simultaneously achieving a broad absorption range, high stability, efficient charge separation, and strong redox capability, which hampers its practical applications. Recently, g-C3N4-based Z-scheme photocatalysts have emerged as research hotspots owing to their robust redox ability, effective charge carrier separation, and capacity to harness visible light for degradation of tetracyclines (TCs) in waters. This review delves into the fundamental photocatalysis, and application of g-C3N4-based Z-scheme photocatalysts for the degradation of TCs pollutants. The review concludes with final remarks and a concise discussion on the prospects of g-C3N4-based Z-scheme photocatalysts.

Samuel Adesina Okueso, Johnson Fejoh

Background: The increased number of quarry activities in Ogu State Nigeria without the commensurate provision of safety resources is an issue of great concern to public health. This study examines the occupational health and safety risks related to quarrying activities among workers. Methods: A cross-sectional survey research design was used, The instrument for data collection was a structured questionnaire developed by the researchers which were: The Knowledge of Occupational Safety and Health-Hazards Questionnaire (KOSHQ) (r = 0.75) and Relationship between Occupational Hazards and Psychological Well-Being Questionnaire (ROHPWQ) (r = 0.84). Descriptive statistics of percentage/frequency were used to describe the demographic characteristics of the participants while Pearson Product Moment correlation was used to test the hypotheses Results: The findings of the study showed that there was a strong, positive, and significant relationship between knowledge of occupational safety, health hazards, and the health of quarry workers (r = 0.940, p-value < 0.05); also, there was a very strong, positive, and significant relationship between occupational hazards and psychological well-being of quarry workers (r = 0.911, p-value < 0.05). a very strong, positive, and significant relationship was observed between knowledge of occupational safety, health hazards, and the health of quarry workers (r = 0.940, p-value < 0.05), there also exists a very strong, positive and significant relationship between occupational hazards and psychological well-being of quarry workers with (r = 0.911, p-value < 0.05). Conclusion: The study concluded that the level of awareness about occupational hazards was The study, recommends that employers provide more training.

Akanksha Gupta, Surendra Kumar Gond, Virendra Kumar Mishra

Present study was performed with the aim to isolate Heavy metal Tolerant- PGPB (HMT-PGPB) from metal-contaminated site and use them for Cr bioremediation. Six different bacterial strains were obtained from the endosphere of Solanum virginicum L. roots and cultured using nutrient agar media amended with 20 mg/L of Cr(VI). The ability of these Cr(VI) tolerant bacterial isolates were assessed for PGP traits like producing siderophores, indole-3-acetic acid (IAA), and phosphate solubilization. The findings indicated that all of the isolates could produce exopolymeric substances and IAA, five of them could produce siderophores, and three could solubilize phosphate. Furthermore, the minimum inhibitory concentrations of these strains werealso determined. These strains were identified as Bacillus licheniformis SxR1, B. tequilensis SxR2, B. subtilis SxR3, B. velezensis SxR4, B. amyloliquefaciens SxR6, and B. stercoris SxR8. To validate the findings, it is crucial to comprehend how Cr(VI) affects Bacillus sp. SxR1 cells to determine the course of uptake and bacterial cell alteration, which was assessed via Fourier Transform-Infrared Spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM).

Le Thanh Thao, Vu Thi Thu Hien, Nguyen Thuy Tram et al.

This study investigated the relationship between MiPs, antibiotic resistance genes (ARGs), and water quality in the Red River Delta. MiPs were collected from water samples at four locations: Hanoi, Ha Nam, Nam Dinh, and Cat Ba Island. Bacteria isolated from MiPs and the surrounding water were analyzed for β-lactamase genes. Polyethylene terephthalate (PET) and polytridecanolactone (PTDL) exhibited notable correlations with coefficients with microbial abundance on MiPs. Aeromonas (99.2 % of all isolates) were the most common bacteria isolated from MiPs, with a fewer Escherichia coli (0.83 %). Of 207 bacterial strains isolated from microplastic, 23 (~11 % of total) were found to carry antibiotic resistance genes, mostly blaTEM (13/23; 56.5 %), blaSHV (9/23; 39.1 %) and blaCTXM-9 (1/23; 4.3 %). All seven environmental factors measured were found to affect the distribution of ARGs and ARBs on MiP surfaces. Chlorophyll-a showed a strong positive correlation with ARB abundance, suggesting a potential link between primary productivity and bacterial colonization. This study is one of the first to report the association of MPs with antibiotic-resistant microbiota and genes. The presence of ARGs on MiPs in areas with high human population highlights the need for effective pollution management strategies to mitigate the risks associated with AMR.

Titilayo Monsurat Musa, Adekola Ridwan Ademola, Adeleye Oluwagbemiga Adewale et al.

Background: The role of balanced diet in the life of an individual physically challenged or not cannot be overlooked. The condition of the physically challenged children attracts little or no attention. Several factors have been identified as causes of malnutrition in physically challenged persons. A nutritional diet is one of the factors that can help to reduce this phenomenon. The study was designed to examine the effect of a nutrition diet on health status of physically challenged students at Ade Okubanjo Institute for the Blind at Ijebu-Igbo. Method: This study used a descriptive survey research design and was conducted in 2022. 120 students were selected as the population of this study of which 100 were retuned valid. The research location was Ade Okubanjo Institute for the Blind, Ijebu-Igbo. A self-structured questionnaire was used to measure the nutrition diet of physically challenged students. To do so, 100 questionnaires were analyzed using a purposive sampling techniques method.  Nutritional diet and health status questionnaire was the instrument used for this study and questions about physical performance, nutritional diet, lack of adequate nutrition and family/parental status questions were asked from the participants. Cronbach’s alpha of NHSQ was 0.72. The data analysis method included the descriptive statistics were analyzed using chi-square. Result: Findings revealed that physical activities performance will significantly influence the nutrition diet of physically challenged children (Cal. value = 125.748a,, p-value = .000.), Lack of adequate nutrition will significantly influence the nutrition diet of physically challenged children (Cal. value = 46.180a,, p-value = .000.) also mental health status significantly influence the nutrition diet of physically challenged children (Cal. value = 41.165a,, p-value = .000.), Family/parental status will significantly affect the nutritional diet intake of the physically challenged (Cal value = 41.165a, , p-value = .000.). Conclusion: The findings concluded that Physical performance, Lack of adequate nutrition, Mental status and Family/parental status significantly affect the nutritional diet intake of the physically challenged students at Ade Okubanjo Institute for the Blind.

Monika Motaghi, Ali Asghar Heidary, Lida Gholizadeh

Background: The capacity to absorb knowledge and manage organizational talent and performance is important to the survival of organizations. The aim of this study was to investigate the relationship between knowledge absorptive capacity and talent management with the performance of the organization. Methods: This applied research used the causal design. The statistical population and sample size were 500 and 217 nurses, respectively.  Three standard questionnaires were used to collect data.  The knowledge absorption capacity questionnaire had Cronbach's alpha 0.705 and included 19 items. Moreover, the organizational innovation variable of the Atlay and Akif questionnaire with Cronbach's alpha 0.795 and 18 items, Hersi and Goldsmith with Cronbach's alpha of 0.762 with 42 items, and Phillips and Rapper with 28 items were used for the talent management component. Data were imported to SPSS20 and analyzed using PLS Descriptive and inferential statistics. Results: The mean age of participants was 24.3±4.5.3 years, 52.54% of nurses were male and 42.46% were female. Also, 61.75% of nurses had a bachelor's degree and 38.15% had an MSc degree. Mean±SD of knowledge acquisition capacity was 17.56±4.63, that of talent management was 17397±4.87, that of organizational innovation was 18.22±4.65. and that of organizational performance was 18.39±4.95. Knowledge acquisition capacity, and talent management had a significant relationship with innovation and organizational performance (1.96<2.57, 3.8, 5.41 and 2.63), and organizational innovation was also correlated with organizational performance (1.96<2.94). According to the results of the Sobel test, the capacity to absorb knowledge and talent management was related to organizational performance with the mediating role of organizational innovation (1.96<2.45 and 3.21). Conclusion: Given the relationship between knowledge absorptive capacity and talent management with organizational performance, managers should be able to effectively improve the capacity to absorb knowledge and spread it throughout the organization.

Jeniffer Gracia, Paola Acevedo, Emiro Trujillo

This research contains a study performed in different companies from the lithographic sector of Bogotá city, Puente Aranda neighborhood. Currently, these companies require high consumption of raw materials and chemical substances to manufacture books, magazines, manuals, posters, brochures, and others. As a result, they lead to wasted paper, inks, glues, and solvents derived from different processes, generating various environmental impacts and occupational diseases. To contribute to these companies' Industrial Safety and Occupational Health and environmental management and identify their environmental impacts, quality management tools and search for solutions were applied to the analysis of processes and products. It allowed the collection of relevant information on resource consumption, waste production (quantity and type of waste) and final disposal, and emissions at the source, heading to identifying the critical points to determine improvement opportunities. According to the results obtained, approximately 21.33 Kg of toxic waste is generated monthly as hazardous waste or wastes during the manufacturing process. It causes different environmental impacts such as atmospheric toxic emissions and contamination of water sources, of which 56% corresponds to the waste and discharges through the production area; these discharges correspond to toxic wastes such as inks, glues, and reagents, which have special handling for this type of companies.

Anuj Singh, Ashish Kumar Sharma, Amit Kumar et al.

Background: Malnutrition remains the ever challenging, public health concern irrespective of age and economic status. Although nutrition is essential irrespective of age but it has peerless role in the school days. The present study was conducted to assess the socio-economic predisposing factors of malnutrition among school children in the Bareilly district of North India. Methods: This cross-sectional study was carried out in Bareilly district of North India. A total of 465 school children were examined for nutritional status and socio-economic factors responsible for malnutrition. Applying multi-stage random sampling technique and pretested, pre-validated schedule was used for data collection which was compiled and analysed with Epi-Info software version 7. Results: The study revealed 40% prevalence of malnutrition among school children. Socio- demographic factors such as gender, caste, type of family and residence were found statistically significant different with nutritional status of child (p<0.05).  However, socio economic factors such as parental education, employment and socio economic conditions were discovered inversely related with malnutrition (p<0.05). Conclusion: The study indicates the necessity to accelerate the government’s coping strategies to win over malnutrition in especially in underserved population of country.

Mehri Zadeh Hosseini, Zohreh Karimiankakolaki

Background: Leadership style is a specific behavioral pattern that is constantly manifested during organizational work and others recognize that person. This study investigated the relationship between leadership styles and positive organizational behavior and stress of COVID-19 in the staff of Shahrekord Health Centers in 2021. Methods: This research was an applied descriptive correlational study. The sample included 148 people from the staff of Shahrekord health centers in 2021. The participants were selected randomly. The tools used in this research were three questionnaires: Likert leadership style questionnaire, Lutans positive attitude organizational behavior questionnaire, and COVID-19 stress questionnaire. Data were analyzed with SPSS20 using descriptive statistics and Pearson correlation test. Results: According to the results, the majority of participants were in the age range of 30 to 35 years, the mean score of leadership style was 86.75 that was high. The mean score of positive organizational behavior was 79.23 that was high, and the mean score of stress of COVID19 was 7.23 that was low. The mean score of leadership style in all cases was positively and significantly correlated with the score of positive organizational behavior (r=0.322, P<0.001) and inversely correlated with the score of stress of COVID-19 (r=-0.314, P<0.001).  Also, the mean score of positive organizational behavior was inversely correlated to the score of stress of COVID19 (r=-0.374, P<0.001). Conclusion: Positive organizational behavior was at a high level in the staff of Shahrekord health centers during the Corona pandemic.  The participatory leadership style was more considered, and had a negative relationship with the stress of Covid-19. Therefore, it seems that it will be possible to establish a correct management style and positive organizational behavior by reducing the stress of Covid-19.

Maryam Adibi, Yousef Gorgi

Background: The absence of one of the parents can bring about major problems in adolescents’ psychological conditions. The objective of the present study was therefore to investigate the effectiveness of solution-oriented group consultation on the increase of resiliency in orphan (fatherless) female adolescents in the city of Isfahan. Methods: The present study was quasi-experimental with pretest, post-test, follow-up and control group research design. The statistical population of the study included all orphan (fatherless) female students in the city of Isfahan in the academic year 2014-2015. Convenient sampling method was used to select the samples; hence, 40 female adolescents were selected as the sample size and were assigned into two groups of 20. eight ninety-minute therapeutic interventions (solution-oriented approach) was administered on the experimental group once a week. The control group, however, did not receive any teaching. Connor-Davidson Resilience Scale was used as the study instrument. And the collected data were analyzed through repeated measures ANOVA via SPSS23 software. Results: The results of the study showed the solution-oriented group teaching being effective on the resiliency of orphan adolescents at the post-stage and follow-up stages (p<0.001). Conclusion: Predicated on the findings of the present study, the solution-oriented teaching method can be applied to increase orphan (fatherless) female adolescents’ resiliency.

Nalok Dutta, Muhammad Usman, Muhammad Awais Ashraf et al.

Reductive dechlorination is a core pathway of chlorination in an anaerobic environment, which can be carried out by fermentative, methanogenic, iron and sulfate-reducing microorganisms. The present review showed the different metabolic ways of microbes with the emphasis on the anaerobic microbial dechlorination (including chemical, biological and nanotechnology-based strategies), that have been employed to mitigate the chlorinated pollutants. Chemical and nanomaterial science has made substantial advancement in several aspects of dechlorination over the past two decades, providing information about the process and the outcome of the reaction. However, these chemical processes are expensive to start with and pose ecological hazards. So, extensive research has been done to come up with eco-friendly biological alternatives). Under anaerobic conditions, dehalorespiring bacteria are capable of dechlorinating chloroethenes by mediating a stepwise replacement of chlorine with hydrogen resulting in the sequential conversion of perchloroethylene (PCE) to trichloroethylene (TCE), dichloroethylene (DCE) isomers, vinyl chloride (VC), and finally, ethane. Among many dehalorespiring bacterial isolates, only a few strains of the genus Dehalococcoides completely converted the chloroethenes to nontoxic ethane. In the paper we will, therefore, focus on this Dehalococcoides spp. Several factors influence the dechlorination activity between different dehalogenating bacteria. The vcrA and bvcA genes dechlorinate VC into ethene, which are essential for complete dechlorination. These pathways offer understanding of potential bioremediation of chlorinated aliphatic or aromatic compounds by Dehalococcoides with the likelihood of highly effective bioremediation.

Collins Otieno Odhiambo, Anafi Mataka, Getachew Kassa et al.

Waste generated from HIV viral load (VL) testing contains potentially hazardous guanidinium thiocyanate (GTC). GTC is toxic to humans and can pollute waters and harm aquatic life if not disposed of appropriately. We assessed gaps in waste management (WM) policies, regulations and practices through a self-assessment scorecard and an online survey questionnaire among 11 African countries participating in a laboratory systems strengthening community of practice and receiving technical assistance to scale-up VL testing. We identified solutions from national stakeholders, technical agencies, and manufacturers to inform interventions for improving WM. Nine of 11 countries did not have WM policies/guidelines in place. Most Countries reported disposing liquid chemical waste into the sewer. Nine countries prioritised the development of policies as a multi-sectoral approach in the short term. High-temperature incineration through cement factory kilns was identified as an effective, inexpensive and high-capacity disposal option for GTC-containing waste in the short term. A long-term consideration with funding from governments and donors were infrastructural investments for conventional high-temperature incineration where cement factory kilns are unavailable/inaccessible. Adequate WM of GTC-containing waste through available funding could provide the necessary impetus to establish comprehensive WM systems addressing all types of healthcare waste through a multisectoral approach.

Zhiming Zhang, Dibyendu Sarkar, Rupali Datta et al.

Per- and polyfluoroalkyl substances (PFAS) represent a family of emerging persistent organic pollutants. Cost-effective remediation of PFAS contamination via chemical or biochemical degradation is challenging due to their extremely high stability. This study reports the removal of two representative PFAS species, perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS), from water by adsorption using aluminum-based water treatment residuals (Al-WTR), a non-hazardous waste generated during the process of drinking water treatment by alum salts. Rapid adsorption of PFOA and PFOS onto Al-WTR followed a pseudo 2nd order kinetic pattern. Lower pH facilitated the adsorption process with a faster adsorption rate and greater adsorption capacity. At pH 3.0 and an initial concentration of 1.0 mg/L, 97.4 % of PFOA and 99.5 % of PFOS were adsorbed onto Al-WTR. Adsorption isotherm modeling showed that the maximum adsorption capacities of PFOA and PFOS on Al-WTR at pH 3.0 were 0.232 and 0.316 mg/g, respectively. Desorption tests indicated that the adsorption by Al-WTR was irreversible, making Al-WTR an excellent candidate for treating PFOA and PFOS in solution. The highly encouraging results of this preliminary study indicate that Al-WTR may be a promising, viable, and cost-effective PFOA/PFOS treatment option for water reuse, industrial wastewater treatment, and groundwater remediation.

Seyed Alireza Afshani, Seyed Mostajad Hosseini-motlagh, Hamide Shiri-Mohammadabad

Background: Considering the role of lifestyle in promoting, maintaining, continuity health and the importance of paying attention to the veterans and their families who have suffered a lot in order to sacrifice for the homeland, the present study intends to compare the lifestyle among veterans and non-veterans in Mashhad city. Methods: This study was conducted using a survey method. The statistical population included the veteran and non-veteran families of Mashhad. A total of 360 questionnaires were filled out in this city. The research instruments were Lifestyle Questionnaire (LSQ) and All Aspects of Health Literacy Scale. The data were analyzed by SPSS v.24. Results: There is not a significant difference between the mean scores of lifestyle in the two groups of veteran and non-veteran in Mashhad (p > 0.05). The comparison of mean lifestyle scores also showed that there was no significant difference between the lifestyle scores of men and women in the non-veteran group and the mean scores of the single and married lifestyle in the veteran and non-veteran group (p > 0.05). There is a significant relationship between education level and health literacy of veteran and non-veteran families with their lifestyle, age, and employment status. They are also related to the lifestyle of their life because of the status they provide for the sacrifices. Conclusion: Comparison of the two groups in terms of lifestyle indicates that the veterans are in a less favorable position than non-veterans in terms of some aspects of lifestyle such as physical health, exercise and health, disease prevention and mental health.

Hasan Zareei Mahmoodabadi, Zahra Delavari

Background: There is the likelihood that cancer in children influences their growth and improvement. The mothers who have children with cancer and experience this hardness along with them play a highly significant role in this complexity. Researchers have considered these lived experiences in a limited way. Method: This qualitative study (phenomenology) was conducted in Mar 2019 among mothers who had children with cancer in Yazd. According to purposive non-random sampling, semi-structured interviews were conducted on participants, and 13 subjects were then selected in order to achieve saturation. The data were analyzed using Dikelmann's 7-step method and MAXQDA 10 software in order to analyze data. Results: The concepts were first extracted and analyzed, 18 sub-categories were then obtained and eventually, 6 main categories including attitudes toward illness, desperation, psychical relief, multidimensional family problems, physician's attitudes, physical-psychological problems, were extracted. Conclusion: Mothers experience pain along with the complex stages of their child who is seriously sick. Additionally, cancer bears many physical, mental, and psychological consequences for their children. It is possible to apply the results of this study in order to develop support strategies and provide services for mothers who have children with cancer as well as their children.