Hasil untuk "American literature"

A. Benjafield, N. Ayas, P. Eastwood et al.

BACKGROUND There is a scarcity of published data on the global prevalence of obstructive sleep apnoea, a disorder associated with major neurocognitive and cardiovascular sequelae. We used publicly available data and contacted key opinion leaders to estimate the global prevalence of obstructive sleep apnoea. METHODS We searched PubMed and Embase to identify published studies reporting the prevalence of obstructive sleep apnoea based on objective testing methods. A conversion algorithm was created for studies that did not use the American Academy of Sleep Medicine (AASM) 2012 scoring criteria to identify obstructive sleep apnoea, allowing determination of an equivalent apnoea-hypopnoea index (AHI) for publications that used different criteria. The presence of symptoms was not specifically analysed because of scarce information about symptoms in the reference studies and population data. Prevalence estimates for obstructive sleep apnoea across studies using different diagnostic criteria were standardised with a newly developed algorithm. Countries without obstructive sleep apnoea prevalence data were matched to a similar country with available prevalence data; population similarity was based on the population body-mass index, race, and geographical proximity. The primary outcome was prevalence of obstructive sleep apnoea based on AASM 2012 diagnostic criteria in individuals aged 30-69 years (as this age group generally had available data in the published studies and related to information from the UN for all countries). FINDINGS Reliable prevalence data for obstructive sleep apnoea were available for 16 countries, from 17 studies. Using AASM 2012 diagnostic criteria and AHI threshold values of five or more events per h and 15 or more events per h, we estimated that 936 million (95% CI 903-970) adults aged 30-69 years (men and women) have mild to severe obstructive sleep apnoea and 425 million (399-450) adults aged 30-69 years have moderate to severe obstructive sleep apnoea globally. The number of affected individuals was highest in China, followed by the USA, Brazil, and India. INTERPRETATION To our knowledge, this is the first study to report global prevalence of obstructive sleep apnoea; with almost 1 billion people affected, and with prevalence exceeding 50% in some countries, effective diagnostic and treatment strategies are needed to minimise the negative health impacts and to maximise cost-effectiveness. FUNDING ResMed.

Sunil V. Rao, M. O’Donoghue, Marc Ruel et al.

AIM The "2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes" incorporates new evidence since the "2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction" and the corresponding "2014 AHA/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes" and the "2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction." The "2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes" and the "2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization" retire and replace, respectively, the "2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease." METHODS A comprehensive literature search was conducted from July 2023 to April 2024. Clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human participants were identified that were published in English from MEDLINE (through PubMed), EMBASE, the Cochrane Library, Agency for Healthcare Research and Quality, and other selected databases relevant to this guideline. STRUCTURE Many recommendations from previously published guidelines have been updated with new evidence, and new recommendations have been created when supported by published data.

Clara-Louise Mourier

Jean Hegland’s Into the Forest (1996) concludes with two sisters and their infant Burl abandoning their family home to embrace life in a neighbouring forest. Western domesticity, symbolised by private bedrooms, is replaced by the plural, biotic community of a centuries-old redwood forest. By taking refuge in a hollow stump, the trio attempts to shed their now obsolete social identity and adapt to a postapocalyptic American West. This process of redrawing the border between inhabited and uninhabitable spaces continues twenty years later in Here in This Next New Now (in French, Le Temps d’après). Burl, now a non-binary “arboreal boy,” undertakes to recount their life within an ecosystem saturated by the non-human. Yet, the character resents their entrapment in the hollow stump chosen by their mothers for protection. Instead, they attempt to reconfigure the entire forest (and beyond) into a potential shelter for human and non-human life. The figure of the bed-stump thus evolves into that of the encampment. In exploring the bed and its redefinitions, this study not only traces the reintegration of the characters into a multispecies world, but also invites readers to consider Hegland’s narrative practices as a refusal to enclose the text in a fixed or stable cartography. On the contrary, the novel ultimately overflows the book as a medium.

Yeshey Dorjey, Deep Kiran Chhetri

ABSTRACT Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates. Pregnancy represents an immunologically vulnerable state, rendering affected mothers more susceptible to severe disease progression. Objective To provide obstetricians and maternal‐fetal medicine specialists with an updated synthesis of the clinical presentation, adverse outcomes, and evidence‐based management strategies for Mpox infection during pregnancy. Methods A comprehensive literature search was conducted across multiple electronic databases‐Web of Science, PubMed, Scopus, ScienceDirect, ProQuest, Cochrane Library, SAGE, Springer, and Google Scholar‐for peer‐reviewed studies addressing Mpox infection in pregnancy. Additionally, international guidelines and consensus statements were reviewed, including those from the World Health Organization (WHO), Royal College of Obstetricians and Gynecologists (RCOG), Centers for Disease Control and Prevention (CDC), Society for Maternal‐Fetal Medicine (SMFM), and American College of Obstetricians and Gynecologists (ACOG). Results Mpox infection during pregnancy is associated with a spectrum of adverse maternal and perinatal outcomes. Pregnant individuals are at increased risk for disease exacerbation, necessitating hospitalization and intensive care. Documented perinatal complications include spontaneous miscarriage, preterm prelabour rupture of membranes (PPROM), preterm birth, intrauterine fetal demise, congenital Mpox infection, low birth weight, and neurodevelopmental delays. Conclusion Pregnant individuals diagnosed with Mpox should be prioritized for hospital admission, isolation, antiviral therapy, and continuous monitoring of maternal and fetal well‐being. Multidisciplinary coordination is essential to mitigate risks and optimize outcomes.

Alicia Hüls

This paper examines Audre Lorde’s The Cancer Journals (2020) and her journey post-mastectomy, in relation to José Muñoz’s theory of disidentification, which he discusses in his book Disidentifications: Queers of Color and the Performance of Politics (1999). For Muñoz, disidentification is a survival strategy of stepping away from predominant societal ideologies. Muñoz’s theory is particularly fruitful for analyzing Lorde’s intersectional experiences and identity struggles of being a queer woman of color with breast cancer, but lacks an element of reidentification. This paper expands on the concept of disidentification and claims that Lorde does not take this passive stand Muñoz proposes but instead reidentifies herself in the face of prevailing gender norms.

Oana Celia GHEORGHIU

Polonius, Romanian author Victor Cilincă’s farcical rewriting of Hamlet, is worth mentioning among the many postmodernist adaptations of Shakespeare’s works, despite the fact that it is virtually unknown to both theatregoers and critics. The play premiered in 1996, in Galati, having been ‘hidden’ in the writer’s drawer for more than a decade for fear that censorship might grasp its anti-totalitarian implications. In 2011, it was translated by Petru Iamandi for an American indie press. Prefaced by a brief overview of drawer literature and “refashioning of Shakespeare’s image along the lines of Communist ideology” (Colipcă-Ciobanu 2016: 26), in communist Romania, the paper focuses on the meta-dimension of the two-act play, as well as on the subversive aspects identifiable at the textual level.

Ryan Le, Ryan Hoang, Joshua Lee et al.

Study Design Retrospective cohort study. Purpose This study aimed to investigate trends in postoperative complications for posterior cervical fusions from 2012 to 2022. Overview of Literature Previous studies analyzing the longitudinal outcomes of posterior cervical fusion from 2003 to 2013 have demonstrated relatively improved postoperative outcomes despite the increasing volume, complexity, and age of the patient population. However, few studies have evaluated these outcomes since 2013. Methods The American College of Surgeons National Surgical Quality Improvement Program database was queried for patients undergoing posterior cervical fusion between 2006 and 2022. Patients aged >18 years with current procedural terminology code 22600 for posterior cervical fusion were included. Patient demographics and comorbidities were recorded, including age, race, body mass index, diabetes mellitus, and hypertension. Annual 30-day complication rates were reported, including wound infection, readmission, reoperation, length of stay, intraoperative blood transfusions, and mortality. Results In total, 25,537 patients undergoing posterior cervical fusion from 2012 to 2022 were included. Variations in the rates of urinary tract infection, deep vein thrombosis, sepsis, reoperation, and mortality were not significant. Wound infection rates increased from 2.4% in 2012 to 4.0% in 2022 (p=0.003). Pneumonia rates increased from 1.2% in 2012 to 1.6% in 2022 (p=0.011). Intraoperative blood transfusion rates decreased consistently from 5.6% in 2012 to 2.8% in 2022 (p<0.001). Readmission rates increased from 6.4% in 2012 to 6.7% in 2022 (p<0.001). The average length of stay decreased from 4.18 days in 2012 to 3.97 days in 2019, before increasing between 2020 and 2022 to 4.17 days in 2022. Conclusions Rates of comorbidities including age, diabetes mellitus, and hypertension have increased among patients undergoing posterior cervical fusion between 2012 and 2022, whereas complication rates have remained relatively similar. The length of stay has shortened despite the higher medical complexity of the patients who underwent surgery.

Roshan Shah

We introduce a modular framework that extends the signature method to handle American option pricing under evolving volatility roughness. Building on the signature-pricing framework of Bayer et al. (2025), we add three practical innovations. First, we train a gradient-boosted ensemble to estimate the time-varying Hurst parameter H(t) from rolling windows of recent volatility data. Second, we feed these forecasts into a regime switch that chooses either a rough Bergomi or a calibrated Heston simulator, depending on the predicted roughness. Third, we accelerate signature-kernel evaluations with Random Fourier Features (RFF), cutting computational cost while preserving accuracy. Empirical tests on S&P 500 equity-index options reveal that the assumption of persistent roughness is frequently violated, particularly during stable market regimes when H(t) approaches or exceeds 0.5. The proposed hybrid framework provides a flexible structure that adapts to changing volatility roughness, improving performance over fixed-roughness baselines and reducing duality gaps in some regimes. By integrating a dynamic Hurst parameter estimation pipeline with efficient kernel approximations, we propose to enable tractable, real-time pricing of American options in dynamic volatility environments.

Asif Naveed Ahmed, Lettie E. Rawlins, Niamat Khan et al.

Abstract Background Hereditary motor and sensory neuropathy (HMSN) refers to a group of inherited progressive peripheral neuropathies characterized by reduced nerve conduction velocity with chronic segmental demyelination and/or axonal degeneration. HMSN is highly clinically and genetically heterogeneous with multiple inheritance patterns and phenotypic overlap with other inherited neuropathies and neurodegenerative diseases. Due to this high complexity and genetic heterogeneity, this study aimed to elucidate the genetic causes of HMSN in Pakistani families using Whole Exome Sequencing (WES) for variant identification and Sanger sequencing for validation and segregation analysis, facilitating accurate clinical diagnosis. Methods Families from Khyber Pakhtunkhwa with at least two members showing HMSN symptoms, who had not previously undergone genetic analysis, were included. Referrals for genetic investigations were based on clinical features suggestive of HMSN by local neurologists. WES was performed on affected individuals from each family, with Sanger sequencing used to validate and analyze the segregation of identified variants among family members. Clinical data including age of onset were assessed for variability among affected individuals, and the success rate of genetic diagnosis was compared with existing literature using proportional differences and Cohen’s h. Results WES identified homozygous pathogenic variants in GDAP1 (c.310 + 4 A > G, p.?), SETX (c.5948_5949del, p.(Asn1984Profs*30), IGHMBP2 (c.1591 C > A, p.(Pro531Thr) and NARS1 (c.1633 C > T, p.(Arg545Cys) as causative for HMSN in five out of nine families, consistent with an autosomal recessive inheritance pattern. Additionally, in families with HMSN, a SETX variant was found to cause cerebellar ataxia, while a NARS1 variant was linked to intellectual disability. Based on American College of Medical Genetics and Genomics criteria, the GDAP1 variant is classified as a variant of uncertain significance, while variants in SETX and IGHMBP2 are classified as pathogenic, and the NARS1 variant is classified as likely pathogenic. The age of onset ranged from 1 to 15 years (Mean = 5.13, SD = 3.61), and a genetic diagnosis was achieved in 55.56% of families with HMSN, with small effect sizes compared to previous studies. Conclusions This study expands the molecular genetic spectrum of HMSN and HMSN plus type neuropathies in Pakistan and facilitates accurate diagnosis, genetic counseling, and clinical management for affected families.

Laela Rohadatul Aisy, Ribut Wahyudi

English, one of the most dominant languages, has undergone transformations and divergences that have created a variety of variations in different parts of the world. The fact is that English has more than 160 acknowledged variations of accents across the globe. Each variation from standard English to a distinctive local reflects its unique culture and history. This study aims to investigate Generation Z's attitudes towards variations of Englishes of their English as foreign language communication experiences. This research adopted qualitative research benefiting from Saraceni's (2010) Space, Culture, Ideology and Psychology (SCIP) model to understand variety of English(es). Four English literature students were selected as respondents when they were still in their 7th semester and aged 21-22 at an Islamic university (under Ministry of Religious Affairs) in East Java, Indonesia. The results revealed that the dominance of American English is still the benchmark in most participants' preferences. A number of competing and interconnected factors such as habits, motivations, and practices with the influence of family, social, educational, and environmental factors shape their preferences on English(es) varieties. The participants showed positive, contradictory attitudes (positive and negative) to negative attitude towards the varieties of Englishes.

Maxence Gouleau

Although they have often been used as metaphors for the act of writing, pregnancy and childbirth have a long history of being left out of literature itself, especially as diegetic events in the novel. Jessie Greengrass’s novel Sight (2018) provides us with a rare pregnant narrator and as such includes pregnancy as a diegetic event and as a theme. Starting with the assessment that pregnancy in literature can be summed up by the image of “a man pac[ing] a carpet” while a woman gives birth outside the frame of the narration, Greengrass’s novel tackles the compulsion to look and to look away, to show and to hide that is at the heart of this image. The novel shows that pregnant bodies have been overlooked by literature not for lack of curiosity, but rather because of an obsessive curiosity for what lies inside them and what comes out of them. By investigating scientist/object relationships alongside mother/daughter relationships, Sight formulates the beginning of an ethics of looking at and of writing about bodies, which lies in a practice of parenthood that acknowledges both curiosity for and discomfort with bodies. The novel thus deconstructs the metaphor of writing as pregnancy and childbirth and points to an ethical way of incorporating bodies, especially female ones, into literature.

David A. Tovar

The process of conducting literature reviews is often time-consuming and labor-intensive. To streamline this process, I present an AI Literature Review Suite that integrates several functionalities to provide a comprehensive literature review. This tool leverages the power of open access science, large language models (LLMs) and natural language processing to enable the searching, downloading, and organizing of PDF files, as well as extracting content from articles. Semantic search queries are used for data retrieval, while text embeddings and summarization using LLMs present succinct literature reviews. Interaction with PDFs is enhanced through a user-friendly graphical user interface (GUI). The suite also features integrated programs for bibliographic organization, interaction and query, and literature review summaries. This tool presents a robust solution to automate and optimize the process of literature review in academic and industrial research.

Goran Petrevski

This paper surveys the empirical literature of inflation targeting. The main findings from our review are the following: there is robust empirical evidence that larger and more developed countries are more likely to adopt the IT regime; the introduction of this regime is conditional on previous disinflation, greater exchange rate flexibility, central bank independence, and higher level of financial development; the empirical evidence has failed to provide convincing evidence that IT itself may serve as an effective tool for stabilizing inflation expectations and for reducing inflation persistence; the empirical research focused on advanced economies has failed to provide convincing evidence on the beneficial effects of IT on inflation performance, while there is some evidence that the gains from the IT regime may have been more prevalent in the emerging market economies; there is not convincing evidence that IT is associated with either higher output growth or lower output variability; the empirical research suggests that IT may have differential effects on exchange-rate volatility in advanced economies versus EMEs; although the empirical evidence on the impact of IT on fiscal policy is quite limited, it supports the idea that IT indeed improves fiscal discipline; the empirical support to the proposition that IT is associated with lower disinflation costs seems to be rather weak. Therefore, the accumulated empirical literature implies that IT does not produce superior macroeconomic benefits in comparison with the alternative monetary strategies or, at most, they are quite modest.

Bhardwaj A

Anish Bhardwaj Departments of Neurology, Neurosurgery, and Neurobiology, University of Texas Medical Branch (UTMB), Galveston, TX, 77555, USACorrespondence: Anish Bhardwaj, University of Texas Medical Branch (UTMB), 9.128 John Sealy Annex, Route 0539, 301 University Blvd, Galveston, TX, 77555, USA, Tel +1-409-772-8068, Email anbhardw@UTMB.EDUAbstract: Medical professionalism is critical toward provision of safe, effective, patient-centered, timely, efficient, and equitable clinical care delivery. The basic tenets of medical professionalism are deeply embedded in the historical context via oaths and expectations. However, standardization of professional conduct and its integration by providers have been a challenge due to the evolving complexity of healthcare organizations (HCOs) and academic medical institutions (AMIs). Increasing heterogeneity of the workforce leads to greater complexity in collaborative teamwork. In this evolving landscape, violations of professional conduct demand closer scrutiny along professional and personal lines. Likewise, actions among minority groups pose challenges between integration and inclusion of certain professional interactions and conduct. Recently, in American HCOs and AMIs, there has been a renewed emphasis on accountability and managing unprofessional behaviors in the delivery of clinical care. This descriptive literature-based treatise explicates the professionalism construct in its historical milieu, underscores key facets of professionalism, highlights principal drivers of unprofessional behaviors, and posits solutions for enhancing and nurturing professionalism in the delivery of clinical care in HCOs and AMIs by a diverse workforce of healthcare providers.Keywords: professionalism, workforce, healthcare, diversity, inclusion

Amanda N. Fletcher MD, MS, Lindsey G. Johnson MBA, Mark E. Easley MD et al.

Category: Ankle Arthritis; Ankle; Hindfoot Introduction/Purpose: The utilization of total ankle arthroplasty (TAA) has increased over the past decade to include bilateral TAAs. The risk-benefit profiles of simultaneous versus staged joint arthroplasty continues to be debated in the literature. There are limited case series reporting outcomes after bilateral TAA with no previous comparison of simultaneous versus staged TAA. It is important to study patients with bilateral pathology as they represent a unique population often with a differing arthritis etiology and an overall more debilitating condition. Thus, we aim to compare bilateral simultaneous versus staged TAAs including perioperative complications and patient reported outcome measures (PROMs). Methods: We performed a comparative cohort study of patients who underwent primary TAA from 2007 to 2019 at a single academic center. Inclusion criteria were primary bilateral TAA performed in simultaneous or staged fashion in patients over 18 years of age. Exclusion criteria were patients with less than two-years follow-up and those with previous tibiotalar arthrodesis or infection. Patient demographics, comorbidities, perioperative complications, and PROMs were collected. PROMs included preoperative and postoperative visual analog scale (VAS) for pain, the Short Form-36 (SF-36) Health Survey, the American Orthopaedic Foot and Ankle Society (AOFAS) score, and the Short Musculoskeletal Function Assessment (SMFA) bother and function sub-scores. Bivariate tests of significance were used to compare variables between the two cohorts. Results: Fifty patients were included with an average clinical follow-up was 52.2 (+-27.3; range 24-109) months. The mean time between staged TAA surgeries was 17.5 months (+-20.1, range 3-74). The mean age was 64.3 (+-10.6, range 21-76) years with 32 (64.0%) men. Many patients had primary osteoarthritis (n=28, 56.0%). Both cohorts experienced improvement in all PROMs at one year, which were maintained at final follow-up with no significant between-group differences (p >0.05). There were no differences in perioperative complication rates with similar overall complications (22.0% vs. 24.0%; p=0.7788) and reoperations (6.0% vs 5.0%; p=0.7354) between the simultaneous and staged cohorts, respectively. The two-year and five-year reoperation-free survival were 96.0% and 90.0% for the staged cohort and 94.0% and 88.0% for the simultaneous cohort, respectively (p=0.4612) Both cohorts had 100% failure-free survival up to eight-years postoperative. One patient in the simultaneous cohort required metal component revision at eight years postoperative. Conclusion: The results of bilateral simultaneous TAA, including patient reported outcomes, perioperative complications, and component survival are comparable to patients undergoing staged TAA. When performed under surgeon expertise in appropriately selected patients, we advocate that simultaneous bilateral TAA is a safe and effective method for the treatment of bilateral end-stage ankle osteoarthritis. Potential benefits of simultaneous TAA warranting further investigation include decreased anesthesia events, surgery time, tourniquet time, length of hospitalization, recovery and rehabilitation time, and overall cost. Future investigations will include dedicated analyses of radiographic outcomes and cost comparisons between these two cohorts.

Maximiliano De La Puente

Dans cet article, nous nous proposons d’aborder les trajectoires de deux collectifs d’artivistes contemporains, qui conçoivent leurs productions à la croisée de l’art, de la politique, de la communication et de la performance, dans le cadre du retour des politiques néolibérales en Argentine. Nous réfléchirons sur les différentes stratégies d’intervention et de diffusion esthétiques/politiques dans l’espace public réel et virtuel qui caractérisent ces collectifs qui comptent parmi les plus importants : Fuerza Artística de Choque Comunicativo (FACC) et Colectivo Fin de UN MundO (FUNO). Notre objectif est de faire une approche des caractéristiques générales de chacun et de présenter une cartographie partielle et fragmentaire des actions réalisées par ces groupes. L’occupation de l’espace public, l’horizontalité, la délibération, les logiques coopératives, l’autofinancement et la persistance des « non représentés » sont des coordonnées centrales pour la configuration des identités de ces collectifs.

Luiz G. Véras, Anna K. F. Gomes, Guilherme A. R. Dominguez et al.

Countless traffic accidents often occur because of the inattention of the drivers. Many factors can contribute to distractions while driving, since objects or events to physiological conditions, as drowsiness and fatigue, do not allow the driver to stay attentive. The technological progress allowed the development and application of many solutions to detect the attention in real situations, promoting the interest of the scientific community in these last years. Commonly, these solutions identify the lack of attention and alert the driver, in order to help her/him to recover the attention, avoiding serious accidents and preserving lives. Our work presents a Systematic Literature Review (SLR) of the methods and criteria used to detect attention of drivers at the wheel, focusing on those methods based on images. As results, 50 studies were selected from the literature on drivers' attention detection, in which 22 contain solutions in the desired context. The results of SLR can be used as a resource in the preparation of new research projects in drivers' attention detection.

Jussi T. S. Heikkila

The Journal of Economic Literature codes classification system (JEL) published by the American Economic Association (AEA) is the de facto standard classification system for research literature in economics. The JEL classification system is used to classify articles, dissertations, books, book reviews, and working papers in EconLit, a database maintained by the AEA. Over time, it has evolved and extended to a system with over 850 subclasses. This paper reviews the history and development of the JEL classification system, describes the current version, and provides a selective overview of its uses and applications in research. The JEL codes classification system has been adopted by several publishers, and their instructions are reviewed. There are interesting avenues for future research as the JEL classification system has been surprisingly little used in existing bibliometric and scientometric research as well as in library classification systems.

Kinohi Nishikawa

Abstract:Kenneth W. Warren’s What Was African American Literature? (2011) compelled literary historians to question deeply held assumptions about periodization and racial authorship. While critics have taken issue with Warren aligning African American literature with Jim Crow segregation, none has examined his account of what came after this conjuncture: namely, the market’s wholesale cooptation of Black writing. By following the career of African American popular novelist Omar Tyree, this essay shows how corporate publishers in the 1990s and 2000s redefined African American literature as a sales category, one that combined a steady stream of recognized authors with a mad dash for amateur talent. Tyree had been part of the first wave of self-published authors to be picked up by major New York houses. However, as soon as he was made to conform to the industry’s demands, Tyree was eclipsed by Black women writers who developed the hard-boiled romance genre known as urban fiction. As Tyree saw his literary fortunes fade, corporate publishing became increasingly reliant on Black book entrepreneurs to sustain the category of African American literature, thereby turning racial authorship into a vehicle for realizing profits.