Hasil untuk "Men"

H. Carter, J. Pearson, E. Metter et al.

E. Lew, L. Garfinkel

M. Litwin, R. Hays, Arlene Fink et al.

M. P. Murray, A. B. Drought, R. Kory

A. Renehan, S. O'dwyer, S. Shalet

R. Lindle, E. Metter, N. Lynch et al.

Wenying Yang, Juming Lu, J. Weng et al.

D. Laaksonen, L. Niskanen, K. Punnonen et al.

E. Seeman

E. Orwoll, M. Ettinger, S. Weiss et al.

S. Bhasin, L. Woodhouse, R. Casaburi et al.

Michele Iannuzzi-sucich, K. Prestwood, A. Kenny

S. Marlow, D. Patton

S. Jee, J. Sull, Jungyong Park et al.

A. Möller-Leimkühler

R. O’Brien, K. Hunt, G. Hart

Douglas P. Schrock, M. Schwalbe

N. Watts, R. Adler, J. Bilezikian et al.

OBJECTIVE The aim was to formulate practice guidelines for management of osteoporosis in men. EVIDENCE We used the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe the strength of recommendations and evidence quality. CONSENSUS PROCESS Consensus was guided by systematic evidence reviews, one in-person meeting, and multiple conference calls and e-mails. Task Force drafts were reviewed successively by The Endocrine Society's Clinical Guidelines Subcommittee and Clinical Affairs Core Committee; representatives of ASBMR, ECTS, ESE, ISCD; and members at large. At each stage, the Task Force received written comments and incorporated needed changes. The reviewed document was approved by The Endocrine Society Council before submission for peer review. CONCLUSIONS Osteoporosis in men causes significant morbidity and mortality. We recommend testing higher risk men [aged ≥70 and men aged 50-69 who have risk factors (e.g. low body weight, prior fracture as an adult, smoking, etc.)] using central dual-energy x-ray absorptiometry. Laboratory testing should be done to detect contributing causes. Adequate calcium and vitamin D and weight-bearing exercise should be encouraged; smoking and excessive alcohol should be avoided. Pharmacological treatment is recommended for men aged 50 or older who have had spine or hip fractures, those with T-scores of -2.5 or below, and men at high risk of fracture based on low bone mineral density and/or clinical risk factors. Treatment should be monitored with serial dual-energy x-ray absorptiometry testing.

Yingying Han, Xingzhao Li, Xin Wang et al.

BackgroundThe recent mpox outbreaks have brought challenges to the global health system. We aimed to study the epidemiological and clinical differences between patients with mpox and patients without mpox among suspected cases during and after 2022.MethodsThis study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.ResultsOur meta-analysis included a total of 22 articles regarding 12,850 suspected cases of mpox. The prevalence of mpox was 54%. We found that the proportion of men among the mpox patients was much greater than that among the non-mpox patients (odds ratio (OR)=9.94, 95% confidence interval (CI): 4.37–22.58), and the same trend was also observed (OR = 11.52, 95% CI: 6.22–21.33) for men who have sex with men (MSM). Sexual intercourse (OR = 4.02, 95% CI: 2.63–6.13), multiple sexual partners (OR = 3.36, 95% CI: 1.99–5.68), and anal sex (OR = 2.40, 95% CI: 1.53–3.77) were more common among mpox patients than non-mpox patients. Sexual contact was more strongly associated with mpox infection (OR = 4.39, 95% CI: 1.77–10.92), whereas nonsexual contact (OR = 0.72, 95% CI: 0.63–0.83) and transmission through health services (OR = 0.55, 95% CI: 0.33–0.93) showed weaker associations. Furthermore, there were significant differences between the two patient groups in terms of sexually transmitted infections, symptoms, complications, lesion locations and types of lesions.ConclusionsOur findings provide a reference for clinicians in the diagnosis and differentiation of mpox. By scientifically understanding these epidemiological and clinical differences, healthcare workers can not only address this epidemic more effectively but also be more fully prepared for the inevitable challenges of future emerging infectious diseases.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD420251141869.

Xiaotang Zhang, Ziyi Chang, Qianhui Men et al.

We propose a real-time method for reactive motion synthesis based on the known trajectory of input character, predicting instant reactions using only historical, user-controlled motions. Our method handles the uncertainty of future movements by introducing an intention predictor, which forecasts key joint intentions to make pose prediction more deterministic from the historical interaction. The intention is later encoded into the latent space of its reactive motion, matched with a codebook which represents mappings between input and output. It samples a categorical distribution for pose generation and strengthens model robustness through adversarial training. Unlike previous offline approaches, the system can recursively generate intentions and reactive motions using feedback from earlier steps, enabling real-time, long-term realistic interactive synthesis. Both quantitative and qualitative experiments show our approach outperforms other matching-based motion synthesis approaches, delivering superior stability and generalizability. In our method, user can also actively influence the outcome by controlling the moving directions, creating a personalized interaction path that deviates from predefined trajectories.