Hasil untuk "Dentistry"

J. Lindhe, N. Lang, T. Karring

P. Branemark, G. Zarb, T. Albrektsson et al.

Muneesh Joshi, Kuhu Sharma

Periodontitis is a chronic inflammatory disease that affects the tissues supporting teeth and represents a significant global health issue. Traditional diagnostic and treatment methods often use a broad approach and fall short due to the complex interactions of genetics, various microbial communities, and environmental factors. Precision periodontics is an emerging field that seeks to transform periodontal care by shifting away from a one-size-fits-all strategy to a more tailored patient management approach. This article examines the fundamental principles, cutting-edge diagnostic tools, innovative treatment strategies, and future directions in precision periodontics. It highlights the importance of understanding the host response, oral microbiome, and genetic factors in creating personalized prevention and treatment plans. We also discuss developments in biomarkers, digital dentistry, regenerative medicine, and new technologies such as artificial intelligence, nanotechnology, and gene editing, all of which aim to improve the predictability of periodontal health outcomes. In addition, the ethical aspects of this personalized approach are addressed, such as informed consent, data privacy, and fair access to advanced care. By combining knowledge from multiple disciplines and leveraging technological advances, precision periodontics promises to greatly enhance patient outcomes and reshape periodontal clinical practice.

J. Dean, D. R. Avery, R. Mcdonald

Francesco Saverio Ludovichetti, Edoardo Stellini, Andrea Zuccon et al.

<b>Objectives</b>: This study aims to review the scientific literature on the prevention of white spot lesions (WSLs) associated with fixed orthodontic treatment. WSLs result from enamel demineralization and pose aesthetic and functional challenges. The study evaluates the effectiveness of various preventive interventions to reduce the risk of WSLs during orthodontic care. <b>Methods</b>: A comprehensive literature search was conducted using MeSH terms such as “white spot”, “fixed orthodontic treatment”, “CPP-ACP”, “topical fluoride”, and “demineralized lesion”, combined with the Boolean operator ‘AND’. Databases searched included PubMed, EMBASE, Scopus, and OpenGrey, focusing on studies published between January 2014 and September 2024. The inclusion criteria required studies to evaluate interventions aimed at reducing WSL risk in patients undergoing fixed orthodontic treatment. A total of 41 articles were screened, with 17 selected based on relevance and methodological rigor. <b>Results</b>: The review identified several effective strategies for preventing WSLs. Topical fluoride applications, particularly high-concentration varnishes, significantly reduced WSL prevalence, with some studies favoring fluoride varnish over other interventions. CPP-ACP and CPP-ACPF formulations demonstrated potential for remineralizing demineralized enamel, especially when combined with fluoride toothpaste. High-fluoride toothpaste and acidulated phosphate fluoride mouthwash were effective in reducing lesion incidence, emphasizing the importance of patient compliance in daily oral hygiene routines. Professional interventions, such as fluoride varnish applications, showed enhanced outcomes when re-applied periodically. <b>Conclusions</b>: Preventing WSLs during orthodontic treatment is crucial for ensuring the aesthetic and functional success of therapy. Strategies combining fluoride-based interventions with casein phosphopeptide formulations offer significant benefits. However, patient education and adherence to recommended oral hygiene practices remain critical. Further research is needed to compare the long-term effectiveness of these interventions and to explore new technologies for WSL prevention.

Almabadi ES, Felemban D, Alekhmimi RK et al.

Eman S Almabadi,1 Doaa Felemban,2 Razan Khalid Alekhmimi,3,4 Muntasir Adnan Aynusah,4 Alla Alsharif,1 Nebras Althagafi,1 Saba Kassim1 1Department of Preventive Dental Sciences, Taibah University, College of Dentistry, Al-Madinah Al-Munawwrah, 42353, Saudi Arabia; 2Department of Oral and Maxillofacial Diagnostic Sciences, Taibah University, College of Dentistry, Al-Madinah Al-Munawwarah, 42353, Saudi Arabia; 3Medical Administration Department,Taibah University, College of Dentistry, Al-Madinah Al-Munawwarah, 42353, Saudi Arabia; 4Department of Dental Surgery, Healthcare Quality and Patient Safety, Ministry of Health, Al-Madinah Al-Munawwarah, 42394, Saudi ArabiaCorrespondence: Eman S Almabadi, Department of Preventive Dental Sciences, Taibah University, College of Dentistry, Prince, Naif Ibn Abdulaziz, Al-Madinah Al-Munawwrah, 42353, Saudi Arabia, Email emabadi@taibahu.edu.saObjective: This study aimed to assess the association between sleep bruxism (SB) among children and parental sociodemographic characteristics and SB risk factors (eg, nose obstruction).Methods: A cross-sectional survey was conducted with 250 parents of children under the age of 13 who visited pediatric dental clinics. Data were collected through a questionnaire completed by parents. Sociodemographic characteristics, the child’s medical history, sleep patterns and parents’ awareness of bruxism and its symptoms were investigated. Descriptive, bivariate and binary logistic regression analyses were performed.Results: The response rate was 85.2% (55% females, 45% males) and 25.8% of the parents self-reported that their children had bruxism. The regression analysis revealed that parents reporting SB among their children were significantly more likely to have SB themselves (8.62 [3.68– 20.16], p = 0.001). While children whose mothers had lower education level and were unaware of bruxism-related symptoms (such as teeth, jaw, or face pain) were less likely to be reported as having SB (0.35 [0.16– 0.75], p = 0.007; 0.36 [0.14– 0.97], p = 0.043, respectively). Parents who identified nose obstruction as a cause of bruxism also had children with a higher likelihood of having SB (5.49 [1.04– 29.08], p = 0.045).Conclusion: The findings highlighted that parental sociodemographic characteristic and SB risk factors associated signficantly with the prevalence of childhood SB.Keywords: sleep bruxism, children, parental sociodemographic factors, Saudi Arabia

Grace Gomez Felix Gomez, Mei Wang, Zasim A. Siddiqui et al.

Abstract Background Decreased salivary secretion is not only a risk factor for carious lesions in Sjögren’s disease (SD) but also an indicator of deterioration of teeth with every restorative replacement. This study determined the longevity of direct dental restorations placed in patients with SD using matched electronic dental record (EDR) and electronic health record (EHR) data. Methods We conducted a retrospective cohort study using EDR and EHR data of Indiana University School of Dentistry patients who have a SD diagnosis in their EHR. Treatment history of patients during 15 years with SD (cases) and their matched controls with at least one direct dental restoration were retrieved from the EDR. Descriptive statistics summarized the study population characteristics. Cox regression models with random effects analyzed differences between cases and controls for time to direct restoration failure. Further the model explored the effect of covariates such as age, sex, race, dental insurance, medical insurance, medical diagnosis, medication use, preventive dental visits per year, and the number of tooth surfaces on time to restoration failure. Results At least one completed direct restoration was present for 102 cases and 42 controls resulting in a cohort of 144 patients’ EDR and EHR data. The cases were distributed as 21 positives, 57 negatives, and 24 uncertain cases based on clinical findings. The average age was 56, about 93% were females, 54% were White, 74% had no dental insurance, 61% had public medical insurance, < 1 preventive dental visit per year, 94% used medications and 93% had a medical diagnosis that potentially causes dry mouth within the overall study cohort. About 529 direct dental restorations were present in cases with SD and 140 restorations in corresponding controls. Hazard ratios of 2.99 (1.48–6.03; p = 0.002) and 3.30 (1.49–7.31, p-value: 0.003) showed significantly decreased time to restoration failure among cases and positive for SD cases compared to controls, respectively. Except for the number of tooth surfaces, no other covariates had a significant influence on the survival time. Conclusion Considering the rapid failure of dental restorations, appropriate post-treatment assessment, management, and evaluation should be implemented while planning restorative dental procedures among cases with SD. Since survival time is decreased with an increase in the number of surfaces, guidelines for restorative procedures should be formulated specifically for patients with SD.

Claire Pédemay, Philippe François, Vincent Fouquet et al.

Abstract Objective To evaluate the shear bond strength (SBS) and adhesive remnant index (ARI) scores of metal brackets to glazed lithium disilicate reinforced glass-ceramics and zirconia according to various surface treatment protocols. Methods A total of 240 lithium disilicate ceramic (LD) and 240 zirconia (Zr) blocks were randomly divided according to sandblasting, hydrofluoric acid (HF) etching, universal primer use, and the adhesive system applied. A maxillary canine metal bracket was bonded to each sample with resin cement (Transbond XT, TXT). SBS tests and ARI score analysis were performed. Four-way ANOVA followed by Tukey’s post hoc test was used for SBS differences, and Fisher’s exact test was used for the ARI scores (p < 0.05). Results All groups combining a universal primer with a universal adhesive with and without sandblasting provided satisfactory SBS values for both LD and Zr. Fractures of the samples were observed only for LD in the groups combining HF with universal primers and universal adhesives with and without sandblasting. Conclusions Combining a universal primer with a universal adhesive could be recommended for orthodontic bonding to both LD and Zr. Regarding their risks (i.e., damaging the restoration surface or burning the oral tissues), sandblasting or HF might not be necessary despite the presence of glaze covering the ceramic surface.

Saif M Al-Mufti , Ali A Abdulkareem , Mike Milward et al.

Background: Dysregulation of Long non-coding (lnc)RNAs has been linked to periodontitis, with potential importance in disease onset and progression. These lncRNAs potentially modulate inflammatory/immune responses during periodontitis. This review aimed to highlight the potential role of Nuclear Paraspeckle Assembly Transcript (NEAT)1 and Metastasis Associated Lung Adenocarcinoma Transcript (MALAT)1 lncRNAs in periodontitis pathogenesis. Methods: A literature search of three electronic databases was performed in SCOPUS, MEDLINE (PubMed) and EMBASE using search terms linking periodontitis/periodontal disease with NEAT1 and MALAT1 lncRNAs. Duplicate publications were removed from the retrieved articles which were then filtered to include the most relevant papers for evidence synthesis. Results: Nine studies (in vitro and in vivo) were included in the final analysis. The total number of studies investigating the role of NEAT1 and MALAT1 in pathogenesis of periodontitis was 4 and 5, respectively. The findings indicated gene expression changes of NEAT1 and MALAT1 in periodontitis compared with periodontal health. Conclusion: No concrete evidence could be withdrawn from this review; however, results suggested that lncRNAs, NEAT1 and MALAT1 could be involved in periodontitis pathogenesis. However, further in vivo studies are required to confirm these findings.

Sina Yarmoradian, Mehrdad Shahraki, Sadra Amirpour Haradasht

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Veena HR, Riya Achamma Daniel, Ashwin Prabhu et al.

Background. Long-term use of many classic chemotherapeutic agents as adjuncts in the management of periodontitis has adverse complications, leading to seeking out naturopathic remedies. Although curcumin has been investigated in managing periodontitis, its therapeutic benefits have not been fully explored due to its limited solubility in an aqueous medium. This study aimed to develop a novel target-specific drug delivery system containing 1% self-nanoemulsifying curcumin (SNEC) in a hydroxypropylmethylcellulose (HPMC) matrix and evaluate the susceptibility of periodontal pathogens to this system in vitro. Methods. Its antibacterial activity against Tannerella forsythia, Porphyromonas gingivalis, Prevotella intermedia, and Aggregatibacter actinomycetemcomitans was evaluated and compared to pure nano-curcumin and SNEC alone by estimating their minimum inhibitory concentrations (MIC). Results. The antibacterial activity of pure nano-curcumin, SNEC, and SNEC in HPMC against the four periodontal pathogens evaluated in terms of MIC was recorded in the range of 0.2‒0.4, 0.4‒0.8, and 0.2‒0.8 µg/mL, respectively. However, the MIC of all three curcumin formulations against the periodontal pathogens tested was higher than that of the standard moxifloxacin. While both pure nano-curcumin and SNEC showed increasing values of inhibition zones with increasing concentrations on disk diffusion assay, lower concentrations of SNEC in HPMC did not show a zone of inhibition against the tested pathogens. Conclusion. The novel delivery system containing SNEC in HPMC may be a potential adjunct in managing periodontitis due to its probable sustained antimicrobial activity against the tested periodontal pathogens.

Lucas Pizzolotto, Rafael R. Moraes

Resin composites are the most versatile restorative materials used in dentistry and the first choice for restoring posterior teeth. This article reviews aspects that influence the clinical performance of composite restorations and addresses clinically relevant issues regarding different direct techniques for restoring posterior teeth that could be performed in varied clinical situations. The article discusses the results of long-term clinical trials with resin composites and the materials available in the market for posterior restorations. The importance of photoactivation is presented, including aspects concerning the improvement of the efficiency of light-curing procedures. With regard to the restorative techniques, the article addresses key elements and occlusion levels for restoring Class I and Class II cavities, in addition to restorative strategies using different shades/opacities of resin composites in incremental techniques, restorations using bulk-fill composites, and shade-matching composites.

Rawan N AlKahtani

The emerging science of nanotechnology, especially within the dental and medical fields, sparked a research interest in their potential applications and benefits in comparison to conventional materials used. Therefore, a better understanding of the science behind nanotechnology is essential to appreciate how these materials can be utilised in our daily practice. The present paper will help the reader understand nanoscience, and the benefits and limitations of nanotechnology by addressing its ethical, social, and health implications. Additionally, nano-applications in dental diagnostics, dental prevention, and in dental materials will be addressed, with examples of commercially available products and evidence on their clinical performance.

S. C. Leal, Eliana Mitsue Takeshita

E. Laneve, Bruna Raddato, M. Dioguardi et al.

In a small and medium-sized dental facility, the correct management of the sterilisation and presterilisation phases plays a fundamental role in good management of instruments and personnel, in order to ensure conditions that are more efficient with less down time. Nowadays, instrument sterilizers are increasingly efficient in achieving results, both in terms of time and size, and ensure that materials are sterile and ready to be stocked in a reasonable time. A literature search for articles related to revision work was performed using electronic databases such as PubMed, Scopus, and Google Scholar. The following keywords have been entered in the previously mentioned databases: sterilisation instruments; dental autoclave; precleaning; instruments disinfectants. The records obtained were screened by three reviewers, and only relevant articles were read full text. In addition, the timings of dental and sterilisation procedures were measured, and from these, suggestions are made in order to improve the efficiency of instrumentation management (facility used as study subject: University Dental Clinic, University of Foggia) as a function of the health-care interventions. We arrived at the conclusion that without doubt, sterilisation of instruments and products plays a fundamental role, but the efficiency of the sterilisation and presterilisation procedures cannot be separated from managing the personnel in charge by giving them specific and precise tasks.

G. Taylor, Kim F. Pearce, Christopher R Vernazza

BACKGROUND It is unclear on how children with compromised first permanent molars (cFPMs) are currently managed in the UK by either general dental practitioners (GDP) or specialists in paediatric dentistry (SPD). AIM Explore the current attitudes to the management of compromised first permanent molars amongst UK general dental practitioners and specialists in paediatric dentistry. DESIGN Self-completed online questionnaire including three clinical vignettes of 7, 9, and 15 years old with cFPM. All registered SPDs (n = 236), as of May 2017, 500 randomly selected GDPs from England, selected from a national performers list, and 52 Scottish GDPs, part of Scottish dental practice research network, were invited to complete the questionnaire. RESULTS About 71.6% (n = 53) of SPDs agreed that children with cFPM should be referred to a paediatric specialist for treatment planning, whereas the reverse for GDPs is true, as 86.8% (n = 138) believe they have a responsibility to treat these teeth. Responses to clinical vignettes suggest a slight preference amongst GDPs to restore cFPM, including root canal treatment, whereas SPDs have a slight preference towards extraction. CONCLUSION Current pathways for cFPM, amongst UK general dental practitioners and specialists in paediatric dentistry, vary greatly between and within each professional group.

M. Duggal, H. Tong, M. Al-Ansary et al.

This systematic review was undertaken in order to develop guidelines for the European Academy of Paediatric Dentistry for the management of non-vital permanent anterior teeth with incomplete root development. Three techniques were considered; apexification by single or multiple applications of calcium hydroxide, use of Mineral Trioxide Aggregate (MTA) for the creation of an apical plug followed by obturation of the root canal, and finally a Regenerative Endodontic Technique (RET). Scottish Intercollegiate Guideline Network (SIGN) Guidelines (2008) were used for the synthesis of evidence and grade of recommendation. Variable levels of evidence were found and generally evidence related to these areas was found to be weak and of low quality. It was not possible to produce evidence-based guidelines based on the strength of evidence that is currently available for the management of non-vital immature permanent incisors. Based on the available evidence the European Academy of Paediatric Dentistry proposes Good Clinical Practice Points as a guideline for the management of such teeth. It is proposed that the long term use of calcium hydroxide in the root canals of immature teeth should be avoided and apexification with calcium hydroxide is no longer advocated. The evidence related to the use of a Regenerative Endodontic Technique is currently extremely weak and therefore this technique should only be used in very limited situations where the prognosis with other techniques is deemed to be extremely poor. The current review supports the use of MTA followed by root canal obturation as the treatment of choice.

R. Moodley, S. Naidoo, J. Wyk

The study was conducted to report on the scope and prevalence of occupational health related‐problems experienced by dentists, dental therapists, and oral hygienists in their practice of dentistry.

Sarmistha Mazumder, A. Nayak, T. Ara et al.

Abstract Hydroxyapatite is one of the most widely investigated bioceramic materials. Recently, several hydroxyapatite composites have been developed for various biomedical uses, including orthopedics and dentistry. In dentistry, hydroxyapatite composite materials are used in dental tissue regeneration, direct pulp capping and pulpotomy, demineralization of enamel, dental drug delivery, and so forth. This current chapter provides a comprehensive review of different hydroxyapatite composites for use in dentistry.

S. El Toum, A. Cassia, Nermine Bouchi et al.

Background Prevalence and distribution of oral mucosal lesions in a sample of Lebanese population attending the School of Dentistry of Lebanese University is necessary to evaluate their oral health situation. Objectives The aim of the present study was to determine the prevalence and distribution of oral mucosal lesions of patients attending the School of Dentistry. Methods A descriptive study was carried out by retrospectively examining a total of 231 medical and clinical examination record files of patients, attending the School of Dentistry Lebanese University for multidisciplinary dental treatments. 178 medical records were retained. Each medical and clinical examination record was done by an undergraduate student and then evaluated by a doctor. The record file included a civil status, chief complaint, medical history, and extraoral and intraoral clinical examination during the period between October 2014 and May 2015. Exclusion criteria were lack of written information in their medical and clinical examination record and being nonevaluated by a doctor. Data regarding age, gender, socioeconomic status, chief complaint, systemic diseases, and drugs intake were collected by using a questionnaire while the type of extraoral and oral mucosal lesions by clinical examination. Results The sample consisted of 102 (57.3%) females and 76 (42.7%) males. The age ranged from 10 to 92 years with a mean age of 40.1 years. Among these subjects, 110 (61.8%) presented with one or more lesions. All patients were Lebanese. The most common lesion diagnosed was coated/hairy tongue affecting 17.4% of the subjects, followed by melanotic macule (11.2%), gingivitis (9.6), linea alba (6.2%), tongue depapillation (5.1), leukoplakia (5.1), traumatic fibroma (4.5), frictional keratosis (3.9%), fissured tongue (3.9%), hemangiomas (3.9%), Fordyce granules (3.9%), dry mucosa (3.4), angular cheilitis (2.2), gingival hyperplasia (2.2), and crenulated tongue (1.7%). Overall, the prevalence of oral mucosal lesions did not significantly differ between sex and age groups. Conclusions The high prevalence of oral mucosal lesions necessitates adequate awareness and management of these lesions in the general population. Dental clinicians should be knowledgeable and familiar with the etiopathogenesis, clinical presentation, diagnosis, and management of these lesions.