Hasil untuk "Otorhinolaryngology"

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DOAJ Open Access 2024
Polysomnographic Phenotype of Positional Obstructive Sleep Apnea

Jae-Seon Park, Young Bok Kim, Il Seok Park et al.

Background and Objectives Obstructive sleep apnea (OSA) is a prevalent sleep disorder characterized by recurrent upper airway obstruction, leading to disrupted sleep and various health complications. Positional OSA (POSA) refers to patients whose OSA severity is significantly influenced by body position, especially when lying supine. This study aimed to evaluate the polysomnographic characteristics of POSA and non-positional OSA (non-POSA) and to assess their clinical implications. Methods This retrospective study included patients diagnosed with OSA who underwent type 1 polysomnography. Patients were categorized into POSA and non-POSA groups based on whether their apnea-hypopnea index (AHI) in the supine position was at least twice as high as that in the lateral position. We collected and analyzed clinical and polysomnographic parameters, including AHI, oxygen desaturation index, arousal index, nadir peripheral oxygen saturation (SpO2), and sleep position proportions. These were compared across different OSA severity levels—mild, moderate, and severe—to assess differences between the POSA and non-POSA groups. Results In total, 500 patients with OSA were analyzed, of whom 63.4% were classified as having POSA. Patients with POSA exhibited milder disease severity than those without, with an average AHI of 23.3±15.3/h versus 43.9±27.9/h, respectively, and a higher nadir SpO2 of 82.8%±6.6% versus 77.1%±9.8%. POSA was more common in patients with mild OSA (76.5%) and moderate OSA (72.8%), while severe OSA cases were predominantly non-POSA (POSA was 47.4%). Moreover, patients with POSA spent significantly more sleep time in the lateral position (43.8%±22.7%) than non-POSA patients (27.2%±28.2%). Conclusion Patients with POSA generally exhibited milder disease and more favorable polysomnographic profiles than non-POSA patients. POSA is prevalent in mild-to-moderate OSA, and identifying it via polysomnography may inform tailored treatment strategies.

Medicine, Otorhinolaryngology
DOAJ Open Access 2022
Effect of age on virtual reality-assisted subjective visual vertical and subjective visual horizontal at different head-tilt angles

Ying Cheng, Yuzhong Zhang, Weijun Ma et al.

Objective: Subjective Visual Vertical (SVV) and Subjective Visual Horizontal (SVH) values may reflect bilateral utricle asymmetry. Bilateral utricle static tension balance can be used to evaluate bilateral otolith lesions and otolith-related central neuropathy. Few studies have examined Virtual Reality (VR)-assisted SVV and SVH values at various head-tilt angles across age groups. The present study aimed to determine the effects of age on VR-assisted SVV and SVH values at different head-tilt angles. Methods: We divided 180 healthy subjects into 6 age groups (n = 30 in each group). VR-assisted SVV and SVH measurements were performed at 9 head-tilt angles (head held vertically, 0°; head tilted 30°, 45°, 60°, and 90° to the left/right) in the roll plane. Results: SVV and SVH values significantly differed with head-tilt angle (p < 0.05). No significant difference was detected in the SVH and SVV values between different age groups (p = 0.632 and p = 0.810, respectively), and no interaction between the age group and the head-tilt angle was found for the SVH and SVV values (p = 0.670 and p = 0.084, respectively). Conclusion: These results suggest that age may have little effect on VR-assisted SVV and SVH at different head-tilt angles. Therefore, VR-assisted SVV and SVH can be evaluated as an effective, fast, and simple way to evaluate utricle function. Level of Evidence: Level 4.

Otorhinolaryngology
DOAJ Open Access 2022
Music Appreciation of Cochlear Implant Users versus Normal Hearing Individuals

Azam Nasresfahani, Shayan Dasdar, Nika Kianfar et al.

Introduction:Cochlear implants (CI) provides speech perception for patients with sensorineural hearing impairment; nonetheless, listening to music is a daunting challenge for them. The present study aimed to compare Iranian CI users and normal hearing (NH) controls in terms of musical habits and appreciation and investigate the possible effect of background variables.Materials and Methods:A total of  37 CI users who underwent surgery at least 18 months before the study and 59 NH listeners were enrolled in this study. The participants were assigned to two age groups: group A (patients ≥15 years old) and group B (patients <15 years old). They were asked to complete the questionnaires to assess their music engagement.Results:In group A, the mean score of music importance was significantly higher in CI users (8.7±2.1), as compared to that in NH subjects (5.8±2.3) (P=0.005). Participation in professional musical training and singing with music was not significantly different between the groups. In group B, the mean score of desire for music was not significantly different between CI users (8.2±1.8) and NH subjects (7.7±2.0). They participated in professional musical training and had a reaction to music almost equally. Singing with music was significantly less common in the CI group (CI 16[61.5%], NH (40[85.1%]) (P=0.023). Selected background variables had no significant effect on the music tendency and habits of CI users.Conclusions:Iranian CI users tended to have a high level of music appreciation in both adult and children groups. Moreover, CI users and NH controls did not significantly differ in the importance of music, devoted time, participation in musical activities, and musical habits.

Otorhinolaryngology
DOAJ Open Access 2022
Does N-acetylcysteine Improve Established Hearing Loss in Guinea Pigs?

Gia Gill MD, Brian W. Blakley MD, PhD

Objective To assess whether multiple injections of a powerful antioxidant can improve established sensorineural hearing loss in guinea pigs. Study Design Animal study. Setting Animal science laboratory, University of Manitoba. Methods A total of 16 guinea pigs were used in our study: 8 underwent unilateral intracochlear neomycin injection, and 8 underwent unilateral saline to serve as controls. After a period of 3 weeks for hearing loss to stabilize, 4 guinea pigs from each group received weekly intraperitoneal injections of N-acetylcysteine (NAC) for 4 weeks. Click auditory brainstem response (ABR) testing was conducted at baseline, weekly after the start of NAC injections, and after the last injection. Pure tone ABR tests were conducted prior to intracochlear injections and at completion of the study. Results Click ABR thresholds were significantly worse in ears treated with neomycin ( P < .001), as expected, but not significantly different when treated with NAC ( P = .664). Thresholds for pure tone ABR were also not statistically different in neomycin-treated ears with or without NAC ( P > .99). Conclusions The aggressive antioxidant therapy performed in this study was not successful in improving established hearing loss via an antioxidant regimen that is known to change the oxidation-reduction potential in the cochlea.

Otorhinolaryngology, Surgery
DOAJ Open Access 2020
A case of cavernous carotid aneurysm diagnosed when diplopia developed after endoscopic sinus surgery

Masayoshi Tei, Eri Mori, Hiromi Kojima et al.

Background: Visual complications of endoscopic sinus surgery usually occur during or immediately after the surgery. We report a case of cavernous carotid aneurysm which developed and gradually worsened after endoscopic sinus surgery was performed. Case presentation: A 63-year-old woman with chronic rhinosinusitis resistant to conservative treatment underwent endoscopic sinus surgery. Despite the surgery being successful and without complications, diplopia developed 2 weeks later. Intracranial imaging revealed a giant cavernous carotid aneurysm as a likely cause of the diplopia. The patient underwent endovascular stenting treatment, and the diplopia was consequently reduced. Conclusions: We experienced a rare case of cavernous carotid aneurysm which started to develop 2 weeks after endoscopic sinus surgery. Possible causes of the aneurysm in this patient are an indirect effect of surgery, such as perioperative hypertension, and bacterial sinusitis.

Otorhinolaryngology
DOAJ Open Access 2019
Clear cell sarcoma of the nasal soft tissue envelope

Dustin A. Silverman, Scott W. Smith, Garth F. Essig, Jr. et al.

Objective(s): Clear cell sarcoma (CCS) is a rare clinical entity with limited head and neck reports. This is the first known case of primary CCS of the nasal soft tissue envelope. The primary objective is to understand the clinical and histopathologic features of CCS of the head and neck. Secondary measures are to recognize the wide differential diagnosis of nasal soft tissue masses and identify treatment strategies to achieve complete resection of nasal soft tissue tumors while optimizing functional and aesthetic results. Methods: Case report. Results: A 38-year-old otherwise healthy Caucasian male presented with a 2 cm subcutaneous mass of the nasal soft tissue envelope. Confined to the lateral nasal wall, the painless mass gradually increased in size over two years and contributed to nasal obstruction. The patient underwent complete resection via an open septorhinoplasty approach with concomitant functional nasal airway surgery. Pathology, immunohistochemistry, and cytogenetics were consistent with CCS (melanoma of soft parts). As no definitive or established adjuvant medical therapy exists, further treatment was suspended in favor of serial imaging. The patient remains clinically free of disease 24 months following diagnosis with subjective improvement in nasal airflow and cosmesis. Conclusion: The differential diagnosis of soft tissue nasal masses is varied. Surgeons should maintain a high index of suspicion for more insidious pathology in otherwise benign-appearing nasal soft tissue masses. An open rhinoplasty approach may be prudent for larger lesions to achieve complete resection with restoration of form and function. Keywords: Clear cell sarcoma, Melanoma of soft parts, Facial plastics, Reconstructive surgery, Rhinoplasty, Nasal reconstruction

Otorhinolaryngology
DOAJ Open Access 2018
Value of the 6-Hour Postoperative Ionized Calcium Slope in Predicting Post- Thyroidectomy Occurrence of Hypocalcemia

Ryan E. Cabance, Emmanuel Tadeus S. Cruz

Objective: To determine the value of the 6-hour postoperative ionized Calcium (iCa) slope, versus 6-hour postoperative Calcium alone, in predicting the occurrence of hypocalcemia in patients who underwent thyroid surgery in a tertiary hospital in Metro Manila. Methods: Study Design:            Retrospective Cross-Sectional Study Setting:                       Tertiary Private Hospital Subjects:                    Pre-operative and 6-hour postoperative ionized calcium determinations were analyzed in 59 patients of the ENT-HNS department in a tertiary hospital in Metro Manila who underwent thyroid surgery from January 2009 to December 2013. Results: The 6-hr postoperative iCa slope (difference between the pre-operative and 6-hour postoperative iCa levels) of ≥0.18 mmol/L correctly predicted 57.1% of patients who eventually developed hypocalcemia, with a specificity of 81.6%, and a positive predictive value of 63.2%. In contrast, the 6-hour postoperative iCa measurement identified only 23.8% (5 out of 21) patients who developed hypocalcemia. Conclusion: The 6-hr postoperative iCa slope increased the probability of identifying patients who developed hypocalcemia from 23.8% to 57.1%. However, as a single determination, this may  not suffice to take the place of serial iCa measurements after thyroid surgery. Keywords: ionized calcium (iCa), hypocalcemia, thyroidectomy

Otorhinolaryngology
DOAJ Open Access 2017
Subcutaneous Emphysema in a Healthy Child: An Unusual Clue for the Diagnosis of Foreign Body Aspiration

Seied Mohsen Emami, Mohammad Shurideh Yazdi, Reza Jafarzadeh Esfehani

Background: Spontaneous pneumomediastinum (SPM) and subcutaneous emphysema are rare findings in children. Various etiologies have been reported for SPM, such as foreign body aspiration in infants, especially in those aged less than three years. In addition to the complications associated with foreign body aspiration, SPM may also become a life-threatening condition if left untreated. In the present report, we discussed a case of subcutaneous emphysema, pneumothorax, and pneumomediastinum in a 13-month-old infant previously treated for pneumonia.Case report: The infant was initially presented with subcutaneous emphysema of the neck, without respiratory distress following pneumonia. In the chest radiography, mediastinal shift and possible pneumothorax were reported, and a chest tube was inserted as the respiratory condition deteriorated. Emergency bronchoscopy showed a foreign body logged in the left respiratory tract, which was removed. Three days later, the chest tube was detached, and the patient was discharged in healthy conditions within the next two days.Conclusion: Pediatricians constantly need to consider the risk of foreign body aspiration, particularly in the presence of respiratory complications, such as SPM, even in the infants with an unreliable history of foreign body aspiration

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