Hasil untuk "Osteopathy"

Francesca Campoli, Maria Chiara Parisi, Antonino Zoffoli et al.

The aim of the study is to compare improvement outcomes in patients (aged between 8 and 18 years old) with idiopathic scoliosis treated with a traditional technique with those treated with an innovative method. The study included 17 participants allocated into two groups: experimental (n = 8) and control (n = 9) groups. The first group was treated with a new method with PosturalSpine® D’Amanti method, twice a week for 30 min per session while the second group was treated with kinesitherapy and traditional tools three times week for 45 min per session. The two groups are similar in the anthropometric characteristics, in baseline Risser index and in the Cobb angles average and no statistically significant differences were found between the two groups. After one year of motor intervention, both treatment groups showed improvements in the progression of scoliotic curves and the PosturalSpine® group showed a significantly higher improvement than the control group. Our results therefore suggest that this new specific method with PosturalSpine® D’Amanti method could play a significant role in improving adolescent idiopathic scoliosis compared to traditional exercises.

Tristan Delion, Aurelien Noyer, Matthieu Gonzalès-Bandrès et al.

Abstract Objectives To comprehensively map the literature on the use of manual therapy (MT) in the management of traumatic brain injury (TBI). Background TBI is a leading cause of long-term disability worldwide, often resulting in persistent physical, cognitive, and emotional symptoms. MT, which is commonly used by chiropractors, osteopaths and physiotherapists (COPs), has been proposed as a nonpharmacological intervention for post-TBI symptom management. However, the scope of supporting evidence remains unclear. Design Scoping Review. Methods Four databases and Google Scholar were searched for peer-reviewed studies published in English or French from 2010 onwards. The inclusion criteria targeted all severities of TBI, with MT interventions delivered by COPs. Data extraction and assessment of methodological reporting were conducted independently by two reviewers via standardised tools. Results Forty-two articles were included, comprising primarily case reports, case series, and randomised controlled trials. Most studies have investigated mild, sport-related TBI and described MT interventions targeting headache, neck pain, and dizziness—often delivered within multimodal care frameworks. A subset of studies has also explored the impact of MT on cognitive, emotional, or sleep-related symptoms, suggesting potential benefits beyond physical outcomes. Moderate to severe TBI has rarely been examined. Reporting limitations were common, particularly regarding adverse events. Conclusion The literature reflects a growing interest in the use of MT for mild, sport related TBI, primarily for managing physical symptoms. Further research is needed to explore broader applications across different populations and TBI severities, investigate underlying MT mechanisms and improve the reporting of safety outcomes.

Luca Comuzzi, Tea Romasco, Massimo Del Fabbro et al.

<b>Background/Objectives:</b> This retrospective study assessed the accuracy of implant positioning with dynamic computer-aided implant surgery (dCAIS) for Toronto Bridge fabrication, using a conometric prosthetic concept and a new intraoral splinting technique (CLIKSS). It compared discrepancies across various anatomical regions, bone qualities, and implant sites. <b>Methods</b>: This study involved 52 patients undergoing full-arch rehabilitation (17 in the mandible, 30 in the maxilla, and 5 in both), with 366 implants placed (125 in the mandible, 241 in the maxilla; 128 in post-extraction sites, and the remainder in healed sites). All implants were immediately loaded. Precision was assessed by measuring linear and three-dimensional (3D) angular deviations between planned and actual implant positions. <b>Results</b>: Measurement errors for apical linear and 3D deviations at the apex and entry point ranged from 0.24 ± 0.10 to 0.55 ± 0.57 mm, and angular deviations varied from 0.32 ± 0.65° to 0.35 ± 0.71°. Maxillary measurements were significantly higher at the entry, apical, and vertical levels, even when comparing anterior and posterior regions with the corresponding mandibular areas, while no differences were found in the angular deviation. Significant discrepancies were observed among different mandibular bone types. Maxillary post-extraction sites exhibited significantly greater deviations than mandibular sites in all parameters except angular deviation. No significant differences were found between healed and post-extraction sites within the same jaw. <b>Conclusions</b>: dCAIS improved implant placement accuracy, leading to predictable prosthetic outcomes, especially during parallel multi-implant insertions. This report introduced dCAIS for conometric/biconometric implant placement combined with the innovative CLIKSS technique as an effective intraoral split method for this prosthesis connection.

Mario Ceddia, Luca Comuzzi, Natalia Di Pietro et al.

Today, dental implantology represents a reliable technique for treating both partial and total edentulism. The fixation of dentures on dental implants can be achieved using various techniques, where the choice of a specific technique depends on the patient’s individual needs, the jawbone’s condition, and the prosthesis design. Currently, the two most common types of prosthetic abutment connections are cemented and screwed, each with its own set of advantages and disadvantages. This study aimed to analyze a novel Morse cone connection system between the prosthesis and implant using finite element analysis (FEA). The analysis of connection retention was conducted using three different approaches: analytical, in vitro, and FEA. Three-dimensional models were created for systems comprising an abutment, healing cap, and crown under three inclination conditions: 0°, 15°, and 30°. Using Ansys finite element software (R1 2023), the impact of the tilt on the system retention was examined. The FEA showed results comparable with the in vitro studies regarding the retention strength for an abutment cap system with a 4° taper, obtaining 66.6 N compared with the 68 N calculated in our in vitro study. The inclination of the abutment affected the system retention due to the hole made in the abutment’s surface, decreasing the contact area between components. The Morse cone prosthesis–implant connection system was found to be the most stable and efficient compared with threaded or cemented systems. The retention was influenced by factors such as the abutment conicity, insertion strength, and the contact surface between components.

Tobias Sundberg, Matthew J. Leach, Stina Lilje et al.

Abstract Background Evidence-based practice (EBP) is fundamental to the delivery of high-quality, safe and effective health care. Naprapaths, manual therapy providers that specialize in the treatment of musculoskeletal pain and dysfunction, became a Swedish licensed health profession in 1994. This study investigated the attitudes, skills and implementation of EBP among licensed naprapaths in Sweden. Methods Licensed naprapaths (n = 950) of Svenska Naprapatförbundet (the Swedish Naprapathy Association) were invited by email to take part in this cross-sectional anonymous online study using the Evidence-Based Practice Attitude and Utilisation Survey in February 2019. Results Fourteen percent (137/950) of invited naprapaths completed the survey. There was an approximately equal gender divide among responders; most were in the mid-career age range, practiced in city areas, and had a university or college certificate/diploma as their highest qualification. The majority of naprapaths agreed or strongly agreed that EBP was necessary in the practice of naprapathy, assisted them in making care decisions, and improved the quality of patient care. Naprapaths’ self-reported skills in EBP were mostly in the moderate to moderate-high range. The majority of participating naprapaths reported infrequent implementation of EBP. Perceived minor or moderate barriers to EBP uptake included a lack of colleague support for EBP and a lack of relevant resources. Access to the internet and free online databases were reported as very useful enablers to improving EBP uptake. Conclusions The licensed naprapaths participating in this survey reported positive attitudes toward EBP, moderate levels of EBP skills, and infrequent implementation of EBP.

Tiago Cúrdia Gonçalves, Tiago Lima Capela, José Cotter

While common pancreatic diseases, such as acute pancreatitis (AP), chronic pancreatitis (CP), and pancreatic cancer (PC), may greatly impact the normal pancreatic physiology and contribute to malnutrition, the adequate nutritional approach when those conditions are present significantly influences patients’ prognosis. In patients with AP, the goals of nutritional care are to prevent malnutrition, correct a negative nitrogen balance, reduce inflammation, and improve outcomes such as local and systemic complications and mortality. Malnutrition in patients with CP is common but often a late manifestation of the disease, leading to decreased functional capacity and quality of life and increased risk of developing significant osteopathy, postoperative complications, hospitalization, and mortality. Cancer-related malnutrition is common in patients with PC, and it is now well recognized that early nutritional support can favorably impact survival, not only by increasing tolerance and response to disease treatments but also by improving quality of life and decreasing postoperative complications. The aim of this review was to emphasize the role of nutrition and to propose a systematic nutritional approach in patients with AP, CP, and PC.

Gordian L. Schmid, Jeremias Kluge, Tobias Deutsch et al.

Abstract Background Osteopathy is a type of complementary medicine based on specific manual techniques. In many countries, including Germany, the profession is not officially regulated, and evidence for the effectiveness of osteopathy is insufficient for most diseases. Nevertheless, many health insurances in Germany offer reimbursement for therapy costs, if osteopathy is recommended by a physician. This cross-sectional survey of German general practitioners (GPs) explored beliefs and attitudes towards osteopathic medicine and described their daily interactions with it. Methods A random sample of 1000 GPs from all federal states was surveyed by mail using a self-designed questionnaire. We collected data on sociodemographics, personal experiences with osteopathy, and attitudes and expectations towards osteopathy. In particular, participants were asked about indications for osteopathic treatment and their beliefs about its effectiveness for different patient groups and diagnoses. A self-designed score was used to estimate general attitudes towards osteopathy and identify factors correlated with greater openness. Additionally, we performed logistic regression to reveal factors associated with the frequency of recommending osteopathy to patients. Results Response rate was 34.4%. 46.5% of participants were women, and the median age was 56.0 years. 91.3% of GPs had referred patients to an osteopath, and 88.0% had recommended osteopathy to their patients. However, 57.5% acknowledged having little or no knowledge about osteopathy. Most frequent reasons for a recommendation were spinal column disorders (46.2%), other complaints of the musculoskeletal system (18.2%) and headaches (9.8%). GPs estimated the highest benefit for chronically ill and middle-aged adults. Female gender (OR 2.09; 95%CI 1.29–3.38) and personal treatment experiences (OR 5.14; 95%CI 2.72–9.72) were independently positively associated with more frequent treatment recommendation. Conclusion GPs in Germany have frequent contact with osteopathy, and the vast majority have recommended osteopathic treatment to some extent in their practice, with foci and opinions comparable to other Western countries. The discrepancy between GPs making frequent referrals for osteopathic treatment while self-assessing to have little knowledge about it demonstrates need for intensified research on the collaboration with osteopaths and how to best integrate osteopathic treatments. Our results may help to focus future effectiveness studies on most relevant clinical conditions in general practice.

Kush S. Mody, Lathan Liou, Tej Joshi et al.

Category: Other Introduction/Purpose: The establishment of the Open Payments Database (OPD) in 2014 made public all financial payments to physicians and hospitals by pharmaceutical and medical device companies. Since then, numerous studies have analyzed industry payment data to elucidate any correlations and trends. The purpose of this study is to examine trends in industry payments to orthopedic foot and ankle surgeons from 2014 to 2018. Methods: The Open Payments Database (OPD) was queried to collect information regarding industry payments to orthopedic foot and ankle surgeons and all orthopedic surgeons from 2014 to 2018. Information was collected on physician education, regional distribution of physicians paid, number of physicians paid, median payment amount, and payment type. Further analyses were conducted on the median payment amount to the top 5% of earners and the other 95%. Median amounts were analyzed using Mann-Whitney U non-parametric tests. Results: Of the 1,416 physicians classified as orthopedic foot and ankle surgeons, Doctors of Osteopathy and Medical Doctors received significantly higher payments than Doctors of Podiatric Medicine (597 vs. 35, P=9x10-113). Only osteopathic and allopathic physicians were included in the main analyses. No significant difference was reported from 2014 to 2018 in the median payments to orthopedic foot and ankle surgeons overall ($616 vs. $810; P=0.13), in the top 5% ($148,864 vs. $158,349; P=0.53), and other 95% ($542 vs. $730; P=0.10). There was no significant difference in payments related to consulting fees, entertainment, food and beverages, gifts, grants, honoraria, royalty and licensing fees, speaker and faculty fees, and travel and lodging. There was a significant increase in industry payments related to education ($750 vs. $1370; P=0.002). Conclusion: Following the establishment of the Open Payments Database in 2014, it was expected that industry payments would decrease significantly. However, no change was seen in payments to orthopedic foot and ankle surgeons and there remains a very large distribution in surgeon compensation. In fact, the top 5% of surgeons compensated account for over 99% of the total industry payments. While there are many factors that could account for this, foot and ankle surgeons should use data extracted from the OPD as a guide to ensure fair and equitable compensation for their work in industry.

Andrea Manzotti, Francesco Cerritelli, Jorge E. Esteves et al.

Preterm birth is a significant risk factor for a range of long-term health problems and developmental disabilities. Though touch plays a central role in many perinatal care strategies, the neurobiological basis of these approaches is seldom considered. C-Tactile afferents (CTs) are a class of unmyelinated nerve fibre activated by low force, dynamic touch. Consistent with an interoceptive function, touch specifically targeted to activate CTs activates posterior insular cortex and has been reported to reduce autonomic arousal. The present study compared the effect of 5 min of CT optimal velocity stroking touch to 5 min of static touch on the heart-rate and oxygen saturation levels of preterm infants between 28- & 37-weeks gestational age. CT touch produced a significant decrease in infants’ heart-rates and increase in their blood oxygenation levels, which sustained throughout a 5-min post-touch period. In contrast, there was no significant change in heart-rate or blood oxygenation levels of infants receiving static touch. These findings provide support for the hypothesis that CTs signal the affective quality of nurturing touch, providing a neurobiological substrate for the apparent beneficial effects of neonatal tactile interventions and offering insight for their optimisation. Keywords: Preterm, Infant, Affective, Touch, C-tactile, Heart-rate

Quesada Gómez JM, Sosa Henríquez M

Lilit V. Egshatyan

Gastroesophageal reflux disease (GERD) is a gastrointestinal motility disorder that results from the reflux of stomach contents into the esophagus resulting in symptoms or complications. GERD is now widely prevalent around the world, with clear evidence of increasing prevalence in many developing countries. Treatment for most people with GERD includes lifestyle changes and medication. Proton pump inhibitors (PPIs) are a mainstay therapy for all gastric acid-related diseases. Long-term use of PPIs is associated with hypomagnesaemia, hypokalemia, hypocalcaemia, osteoporosis and bone fractures, chronic renal disease, acute renal disease, and other. Clinical concerns arise from a small but growing number of case reports presenting PPI-induced hypomagnesaemia. In 2011 the U.S. Food and Drug Administration is informing the public that prescription PPI may cause low serum magnesium levels if taken for prolonged periods of time. In this article, we present the case of a 56-year-old patient with muscle cramps, violation of cardiac rhythm, lethargy and other caused by hypomagnesaemia, hypocalcaemia and hypokalemia with a low parathyroid hormone level while using a PPI. After magnesium repletion abnormalities resolved. A causal relation with PPI use was supported by the recurrence of hypomagnesaemia after re-challenge.

Bedia Díaz G, Carrillo López N, Solache Berrocal G et al.

Introducción: En pacientes con enfermedad renal crónica (ERC), la hiperfosfatemia agrava tanto la hiperplasia paratiroidea como la síntesis y secreción de PTH. La mayor hiperplasia se asocia a descensos en la expresión génica de los receptores de calcio (CaSR), vitamina D (VDR) y también de ?-Klotho, induciendo resistencia de la glándula paratiroides para responder tanto al tratamiento como a los aumentos de FGF23. Este estudio examinó la posible contribución epigenética del fósforo elevado en agravar el hiperparatiroidismo secundario (HPTS). Material y métodos: Se comparó el grado de metilación mediante pirosecuenciación de bisulfito en secuencias ricas en CpG de los promotores en los genes del CaSR, VDR, PTH y ?-Klotho en ADN de glándulas paratiroides de ratas urémicas alimentadas con dieta con contenido normal y elevado en fósforo. Resultados: La dieta rica en fósforo incrementó la expresión de PTH y causó una marcada reducción del grado de metilación en el promotor del gen de PTH. En cambio, las regiones promotoras de los genes de CaSR, VDR y ?-Klotho no mostraron diferencias significativas en el porcentaje de metilación entre ambos grupos de ratas, no siendo, por tanto, éste el mecanismo determinante de la disminución de la expresión de estos genes observada en el HPTS. Conclusiones: Las alteraciones epigenéticas inducidas por la dieta rica en fósforo en el HPTS, en particular la hipometilación del gen de la PTH, podrían contribuir a los aumentos que se producen en la síntesis y secreción de esta hormona. La identificación de los mecanismos implicados permitiría diseñar mejores tratamientos para el HPTS en fases tempranas de la ERC.

M A ShALINA, M I YaRMOLINSKAYa

Проблема медикаментозной терапии остеопороза по-прежнему остается актуальной. Открытие системы RANKL/RANK/OPG позволило рассчитывать на преодоление недостатков существующих схем лечения постменопаузального остеопороза (ПМО). Деносумаб является человеческим рекомбинантным моноклональным антителом к RANKL, влияющим на процессы активации и выживаемости остеокластов. Цель. Оценить состояние минеральной плотности костной ткани (МПК) аксиального скелета пациенток с ПМО на фоне терапии Деносумабом в течение года. Оценить уровень маркеров костного метаболизма, качество жизни и переносимость терапии. Материал и методы. Обследована 31 женщина с диагнозом ПМО в возрасте от 46 до 70 лет (57,2 ±1,4 года). Возраст наступления менопаузы в среднем составил 46,7±0,9 года, у 8 женщин наблюдалась ранняя или преждевременная менопауза. У 9 пациенток выявлен семейный анамнез ПМО, 2 женщины имели дефицит массы тела, у 6 больных - низкоэнергетические переломы различных локализаций. 8 женщин имели заболевания желудочно-кишечного тракта. Ранее 11 больных использовали для лечения ПМО бисфосфонаты, поводом для изменения терапии явились недостаточная эффективность или плохая переносимость терапии. Определение МПК проводилось методом двухэнергетической рентгеновской абсорбциометрии (Hologic Discovery) в начале исследования и через 12 месяцев лечения Оценка боли в спине проводилась по данным опросника. Деносумаб (Пролиа) вводился подкожно каждые 6 месяцев в форме 1 мл раствора в дозе 60 мг. Пациентки получили 2 инъекции на фоне ежедневного применения препаратов кальция и витамина Д. Результаты. Остеопороз поясничного отдела позвоночника выявлен у 13 женщин, бедра - у 7, остеопороз обеих локализаций - у 11 больных. Уровень ионизированного кальция в среднем составил 1,14±0,02 ммоль/л, 25-гидрок-сивитамина Д - 26,8±2,5 нг/мл, остеокальцина - 22,7±1,8 нг/мл, паратиреоидного гормона - 44,5±4,7 пг/мл, уровень креатинина был в норме у всех обследованных. Через 12 месяцев, после 2 инъекций препарата, у большинства женщин выявлен прирост МПК в поясничном отделе позвоночника (от 0,2% до 11,5%). Наибольший прирост МПК наблюдался у женщин, не получавших ранее терапию остеопороза. В среднем BMD (L1-L4) до лечения и после составил 0,772±0,014 г/см2 и 0,807±0,010 г/см2, соответственно (р<0,05). Процент прироста МПК в проксимальных отделах бедра был ниже, чем в позвоночнике, и не превышал 5,1%,, у большинства женщин изменения МПК в этой зоне отсутствовали или были недостоверными. BMD шейки бедра до лечения составила 0,589±0,013 г/см2, после лечения - 0,596±0,012 г/см2 (р>0,05). Уровень маркера резорбции костной ткани Сtх существенно снизился через 3 месяца после 1-ой инъекции (до лечения 0,381±0,035 нг/мл и 0,250±0,040 нг/мл после лечения (р<0,05) Жалобы на боли в поясничной области в начале исследования предъявляли 19 женщин, через 6 месяцев болевой синдром сохранялся у 11 женщин, через 12 месяцев - только у 5 пациенток. Новых переломов за время лечения не выявлено Заключение. Препарат Пролиа (Деносумаб) характеризуется высокой эффективностью в лечении остеопороза, снижении риска переломов и уменьшении болевого синдрома. Положительная динамика наиболее выражена в поясничном отделе позвоночника. Наибольший прирост МПК отмечен у женщин с изначально более низкой МПК, не получавших ранее антирезорбтивную терапию. Для получения дальнейшего прироста МПК целесообразно продолжать проводимую терапию.

Torrubia B, Alonso I, López-Ramiro E et al.

Introducción: La cuantificación de 25(OH) vitamina D total en sangre es el marcador más preciso del estado de vitamina D en un individuo. La técnica patrón-oro para su medición es la cromatografía líquida/espectrometría de masas en tándem (LC-MS/MS), aunque actualmente los laboratorios clínicos utilizan de rutina técnicas de quimioluminiscencia. El objetivo del estudio fue comparar las concentraciones de 25(OH) vitamina D obtenidas mediante dos métodos automatizados comerciales y estudiar la correlación de dichos métodos con la técnica de referencia LC-MS/MS. Material y método: Se cuantificaron los niveles de 25(OH) vitamina D en 1.000 muestras de suero del laboratorio de Bioquímica de la Fundación Jiménez Díaz mediante 2 métodos automatizados comerciales por detección de quimioluminiscencia: ADVIA CENTAURO® (SIEMENS) y LUMIPULSE® G1200 (FUJIREBIO). Entre todas las muestras analizadas, las 50 más discordantes entre sí se enviaron para ser evaluadas por la técnica de referencia LC-MS/MS. Resultados: Los resultados obtenidos indican que existe una buena correlación entre los dos métodos: CCI=0,923 (0,914-0,932), siendo los valores de LUMIPULSE® G1200 un 10% superiores a los de CENTAURO®. Con respecto a las 50 muestras seleccionadas, podemos observar que existe una buena correlación entre los dos inmunoensayos con la técnica LC-MS/MS, aunque ambos métodos infraestiman considerablemente los resultados de 25(OH) vitamina D con respecto al patrón-oro. Discusión: Aunque ambas técnicas son adecuadas para su utilización, habría que plantearse si la “epidemia” mundial de hipovitaminosis D se debe a la metodología de análisis utilizada. Esta variabilidad entre inmunoensayos se solucionaría estandarizando las diferentes técnicas comerciales con los materiales de referencia elaborados por el NIST.

I R GAFAROV, R R YaKUPOV, E I NIZAMOVA

На сегодняшний день изучению остеоартроза тазобедренного сустава посвящено большое количество публикации, как в отечественной, так и в зарубежной литературе, однако, один из узких разделов по изучению преморбидного состояния костного метаболизма у пациентов ортопедического профиля в предоперационном периоде недостаточно изучен. В связи с этим целью исследования послужила оценка структуры костного метаболизма у пациентов перед хирургическим лечением по технологии артропластики тазобедренного сустава. Материал и методы. Было исследовано 437 пациентов с остеоартрозом тазобедренного сустава (III-IV стадии по Kellgren - Lawrence) в возрасте от 50 до 90 лет (63,8 ± 7,8 SD), которым предстояло хирургическое лечение по технологии артропластики тазобедренного сустава. Измерения МПКТ оценивалось с помощью двухэнергетической рентгеновской абсорбциометрии (DXA) «Hologic discovery W» (США). Распределение пациентов осуществлялось в зависимости от МПКТ в области Total hip контралатеральной конечности. Статистическая обработка данных проводилась при помощи методов параметрической и непараметрической статистики. Результаты. Полученные результаты лучевого мониторинга МПКТ по Т - критерию согласно ВОЗ менее -1 SD была выявлена у 51 (11,6%) пациента, у 319 (73%) пациентов МПКТ находилось в диапазоне от -1,0 до - 2,5 SD было установлено как остеопенический синдром и у 67 (15,3%)) пациентов МПКТ была менее -2,5, что расценивалось как остеопороз. Выводы. Таким образом, большинство пациентов рассматриваемого профиля на момент госпитализации находятся в состоянии остеопенического синдрома, что является независимым фактором риска в послеоперационном периоде, и требует медикаментозной коррекции с целью снижения осложнений в первый год после операций.

E E VOLKOV, S E NOSTAEVA, Kh B KARIMOVA

Цель: ретроспективный анализ результатов лечения без-операционным методом тазобедренных суставов (ТБС) при асептическом некрозе головки бедренной кости (АНГБК). Материал и методы: в исследование включено 60 больных в возрасте от до 3 до 70 лет с диагнозами двухстороннего АНГБК II-IV стадии. Пациенты получали комплексное лечение не менее 6 месяцев, включавшее: ЛФК, проведение процедур с использованием терапевтических аппаратов «Остеон-1» или «НС-5» с накожными фитоаппликаторами, фитованны, приём лекарственных препаратов и органо-минеральных комплексов. В обязательном порядке предписывался ортопедический режим с использованием костылей. Каждый курс лечения, проводившегося пациентами в домашних условиях, составлял 3 месяца. До начала и по завершении 3-месячного курса лечения пациенты проходили обследование: обзорную рентгенографию ТБС, денситометрию, анкетирование по шкале Harris и динамический контроль маркёров метаболизма костной ткани. Результаты лечения оценивали на основании совокупной динамики клинических, инструментальных и лабораторных показателей. Результаты: положительные результаты комплексной терапии в виде снижения выраженности болевого синдрома, увеличения амплитуды движений, повышения качества жизни пациентов отмечались уже после 1-го месяца лечения. Однако для достижения стойкого положительного эффекта требовалось в среднем 15 месяцев (5 курсов лечения). При этом отличные и хорошие результаты зарегистрированы у 46 (76,6%), удовлетворительные - у 7 (11,6%) пациентов. Не отмечено эффекта у 2-х пациентов, которым потребовалось тотальное эндопротезирование ТБС. Эффективность лечения в первую очередь зависела от полноты соблюдения пациентами всех рекомендаций Выводы: 1. Предлагаемый безоперационный метод может рассматриваться как инновационый подход в лечении и реабилитации у больных страдающих АНГБК. 2. Комплексное использование всех взаимодополняющих элементов разработанного метода обеспечивает поступление микроэлементов (Ca, P, Mg, Zn) из многокомпонентных фитосборов в ТБС, улучшая микроциркуляцию и способствуя регенерации его тканей. 3. Представленный метод является патогенетически обоснованным, с минимальным количеством противопоказаний и нежелательных эффектов и возможностью проведения лечебно-реабилитационных мероприятий в домашних условиях.

López-Ramiro E, Rubert M, Mahillo I et al.

Introducción: Cada vez está más demostrado el papel de la vitamina D en múltiples patologías, una de ellas el desarrollo de un hiperparatiroidismo secundario al déficit de vitamina D. Los métodos de laboratorio de cuantificación de vitamina D en suero no estaban bien estandarizados hasta ahora, por lo que no podía establecerse con certeza a partir de qué niveles de vitamina D se producían determinadas anomalías como la elevación de la PTH. Nuestro estudio pretende determinar por debajo de qué niveles de vitamina D nos encontraremos con niveles de PTH anormalmente elevados, realizando la determinación de vitamina D en el laboratorio con una técnica debidamente estandarizada y fiable. Métodos: El estudio descriptivo y retrospectivo se realizó con pacientes mayores de 18 años en los que se hicieron simultáneamente determinaciones de PTH, 25(OH) vitamina D (25OHD) y que además tuvieran valores normales de calcio, filtrado glomerular y fósforo. Para la determinación de vitamina D se utilizó un método de electroquimioluminiscencia estandarizado con respecto a la técnica de gases-masas. Por el programa estadístico Stava versión 11 se calculó el valor de 25OHD para el que la PTH se elevaba por encima de 70 pg/ml con la mayor sensibilidad y especificidad. Resultados: Se incluyeron 4.083 pacientes, de los que 2.858 eran mujeres (70%) y 1.225 (30%) varones. La edad media de la población estudiada fue 60,60 años (desviación estándar, 15,29). El 74% de la población tenía una PTH en suero por debajo de 70 pg/ml (valores considerados normales) y el 26% mayor de 70 pg/ml. Al construir la curva de ROC de los niveles de 25OHD, en función de valores de PTH por debajo o por encima de 70 pg/ml, el área bajo la curva fue 0,5962 (p<0,0001). El punto de corte teniendo en cuenta conjuntamente la sensibilidad y la especificidad que determinaban los valores de vitamina D para predecir los valores de PTH por encima de 70 pg/ml fue 24 ng/ml. De los pacientes con PTH normal, el 71% tenían valores de vitamina D normales, mientras que, de los pacientes con PTH elevada (mayor de 70 pg/ml), casi la mitad presentaban una vitamina D menor de 24 ng/ml, porcentaje que aumentaba según se iba elevando la PTH. Conclusiones: El valor de 25OHD que muestra una mejor especificidad y sensibilidad para predecir valores anormalmente elevados de PTH es 24 ng/ml, valor superior al presentado en trabajos anteriores (alrededor de 18 ng/ml). Con los resultados de este estudio, realizado con un método debidamente calibrado, se puede decir que el 44,9% de pacientes con valores de vitamina D menores de 24 ng/ml presenta niveles de PTH anormalmente elevados, con una función renal normal y valores de calcio y fósforo normales. Este porcentaje es menor entre los 18 y 40 años (24%) y llega al 49% por encima de los 60 años. Estos pacientes podrían tratarse con vitamina D para evitar un posible hiperparatiroidismo secundario al déficit de dicha vitamina. Es importante tener en cuenta que el método de determinación de vitamina D utilizado debe estar debidamente estandarizado con respecto al método de gases-masas.

Emanuele Luciani, Patrick L S van Dun, Jorge Eduardo Esteves et al.

1) to assess the preparedness to practice and satisfaction in learning environment amongst new graduates from European osteopathic institutions; 2) to compare the results of preparedness to practice and satisfaction in learning environment between and within countries where osteopathy is regulated and where regulation is still to be achieved; 3) to identify possible correlations between learning environment and preparedness to practice.Osteopathic education providers of full-time education located in Europe were enrolled, and their final year students were contacted to complete a survey. Measures used were: Dundee Ready Educational Environment Measure (DREEM), the Association of American Medical Colleges (AAMC) and a demographic questionnaire. Scores were compared across institutions using one-way ANOVA and generalised linear model.Nine European osteopathic education institutions participated in the study (4 located in Italy, 2 in the UK, 1 in France, 1 in Belgium and 1 in the Netherlands) and 243 (77%) of their final-year students completed the survey. The DREEM total score mean was 121.4 (SEM: 1.66) whilst the AAMC was 17.58 (SEM:0.35). A generalised linear model found a significant association between not-regulated countries and total score as well as subscales DREEM scores (p<0.001). Learning environment and preparedness to practice were significantly positively correlated (r=0.76; p<0.01).A perceived higher level of preparedness and satisfaction was found amongst students from osteopathic institutions located in countries without regulation compared to those located in countries where osteopathy is regulated; however, all institutions obtained a 'more positive than negative' result. Moreover, in general, cohorts with fewer than 20 students scored significantly higher compared to larger student cohorts. Finally, an overall positive correlation between students' preparedness and satisfaction were found across all institutions recruited.

O M Lesnyak, O B Yershova, K Yu Belova et al.

Introduction. The incidence of fractures of the proximal femur (FPF), fractures of the forearm and humerus was studied in two cities of the Russian Federation. This index was used to create the Russian model FRAX and to assess the present and future burden of fractures. Objective. So far, little is known about the epidemiology of fractures in Russia. The aim of the study was to determine the incidence of major fractures to create a Russian model of FRAX and evaluate the present and future burden of fractures. Materials and methods. In well-defined populations of two Russian cities, we had determined a number FPF and forearm fractures of the humerus for 2-2-year period. Data were combined and the resulting incidence used to calculate FRAX model for the Russian Federation and to calculate the projected number of fractures in the Russian Federation in 2010 and 2025. Results. A total of 6012 fractures were identified. Among all FPF, 27% of Pervouralsk and 1.8% in Yaroslavl were not registered on the official data of medical institutions. The incidence of fractures increased with age and was higher in women than in men. The probability of experiencing a FPF in later life at the age of 50 years was 4% of men and 7% of women. Total number FPF in 2010 was 112 thousand cases and it is expected to rise by 2025 to 159 thousand a year. The estimated number of major osteoporotic fractures will increase from 590 thousand to 730 thousand cases for the same period. Conclusions. Osteoporotic fractures are a serious health problem for Russia. It is necessary to take urgent measures to improve emergency care at FPF and long-term care for this and other osteoporotic fractures.

A. Palumbo Piccionello, F. Dini, A.M. Tambella et al.

A five-year-old dog was referred with a five-month history of lethargy, decreased appetite, cough and intermittent forelimb lameness. Radiographs revealed an intra-thoracic lesion and a marked periosteal bone apposition of the second digit on the left forelimb. As it was palisading and circumferential, the latter appeared typical of hypertrophic osteopathy (HO). A grass awn in a sub-lobar ramification of the right caudal bronchus was identified and removed by bronchoscopy. At three months follow-up, the digit appeared clinically normal. On radiographs the periosteal bone reaction had decreased, indicative of resolving hypertrophic osteopathy. Thoracic radiographs showed no abnormalities five months after foreign body removal and the bone lesion on the digit had disappeared. Successful treatment of the pulmonary foreign body abscess led to spontaneous regression of HO and eventually to complete resolution of clinical signs. To the authors' knowledge, this is the first reported case of HO secondary to a bronchial-pulmonary grass an abscess.