This study aimed to analyze the effect of cayenne pepper (Capsicum frutescens L.) juice on the histological structure of colonic mucosal crypts and the number of goblet cells in Wistar rats. Cayenne pepper contains capsaicin, flavonoids, and vitamin C, which exhibit both pro-inflammatory and anti-inflammatory properties. Goblet cells play an essential role in maintaining intestinal homeostasis by producing mucin that protects the mucosa from inflammation. This quasi-experimental study employed a post-test only control group design using 20 male Wistar rats divided into one control group and four treatment groups receiving cayenne pepper juice at doses of 45 mg, 90 mg, 135 mg, and 180 mg daily for seven days. On day seven, the rats were terminated, and colon tissues were processed for histological examination using hematoxylin-eosin staining. Observations were conducted under 40× magnification to measure crypt length and count goblet cells. Data were analyzed using the Shapiro–Wilk normality test followed by one-way ANOVA. The results showed significant differences among groups (p<0.05). The 90 mg group exhibited the shortest mean crypt length, while the 135 mg group had the lowest number of goblet cells, indicating greater mucosal damage. In contrast, the 180 mg group demonstrated the longest crypt length and highest goblet cell count, suggesting mucosal repair. These findings indicate that cayenne pepper induces dose-dependent effects on colonic mucosa, with higher doses potentially promoting mucosal regeneration.
We revisit a classic proof of the Blaschke-Lebesgue theorem. It is based on the support function of a convex curve and the approximation of constant width curves by Reuleaux polygons.
In this paper we state two quantitative Sylvester-Gallai results for high degree curves. Moreover we give two constructions which show that these results are not trivial.
David Blanco, Eva María Rubio, José Manuel Sáenz de Pipaón
et al.
Multimaterial hybrid compounds formed from lightweight structural materials have been acquiring great importance in recent years in the aeronautical and automotive sectors, where they are replacing traditional materials to reduce the mass of vehicles; this will enable either an increase in the action ratio or a reduction in the fuel consumption of vehicles and, in short, will lead to savings in transport costs and a reduction in polluting emissions. Besides, the implementation of production and consumption models based on the circular economy is becoming more and more important, where the repair and, for this purpose, the use of recyclable materials, is crucial. In this context, the analysis of a repair process is carried out by re-drilling Mg-Al-Mg multimaterial components using experimental design (DoE) based on Taguchi methodology, an analysis of variance (ANOVA) and descriptive statistics. The study concludes which are the significant factors and interactions of the process, comparing the results with previous similar studies, and establishing bases to determine the optimum thicknesses of hybrid magnesium-based component plates of drilled parts in the aeronautical industry, guaranteeing surface roughness requirements in repair and maintenance operations throughout their lifetime.
The discrete functional $L_p$ Minkowski problem is posed and solved. As a consequence, the general affine Pólya-Szegö principle and the general affine Sobolev inequalities are established.
It is shown that there exist Banach spaces $X,Y$, a $1$-net $\mathscr{N}$ of $X$ and a Lipschitz function $f:\mathscr{N}\to Y$ such that every $F:X\to Y$ that extends $f$ is not uniformly continuous.
We prove several stability and volume difference inequalities for projections of convex bodies and apply them to prove a hyperplane inequality for surface area of projection bodies.
Following Coxeter we use barycentric coordinates in affine geometry to prove theorems on ratios of areas. In particular, we prove a version of Routh-Steiner theorem for parallelograms.