Deep coal resources with abundant reserves and considerable thermal potential are receiving increased attention in mining engineering, given the accelerating transformation of the global energy structure and the growing demand for clean energy. To address extraction challenges and environmental pressures while ensuring economic feasibility and sustainable development, efforts are made to enable carbon reduction and green transformation under high-efficiency utilization of deep coal resources. A systematic review of “deep coal resource fluidized mining”, “coal chemical mining”, and “coal-based power” informs the introduction of a detonation-generation mining approach and its technical framework. The approach places coal-powder detonation combustion technology at its core and integrates advanced detonation combustion-mechanical/magnetohydrodynamic power generation, forming a detonation-turbine/MHD hybrid power system that supports efficient conversion and clean utilization of coal resources. Four fundamental theories are presented, including the Coal-powder Detonation Energy Release mechanism, the Coupled Coal-powder Detonation-generation Power Scheme, a Full Life Cycle Detonation-power Generation Dynamic Management Mechanism, and the Blasting-electric Power Deep coal mining theory and method. Discussion centers on four key technologies: Stable coal/gas two-phase detonation, detonation model construction and dynamic process optimization, detonation-based power generation efficiency assessment, and comprehensive design for detonation-based coal mining, demonstrating their role in upgrading deep coal mining practices. On this foundation, a systematic engineering strategy is proposed to clarify the synergy between mining processes and the detonation-based power generation mode, highlight safety management and process optimization priorities at each critical stage, and refine the overall detonation-generation pathway for deep coal resource development. This pathway offers valuable insights for establishing a coal-based power system and promoting the clean and efficient utilization of deep coal resources in China.
Hussein A. Kazem, Miqdam T. Chaichan, Ali H.A. Al-Waeli
et al.
Integrating the photovoltaic/thermal (PV/T) system in green hydrogen production is an improvement in sustainable energy technologies. In PV/T systems, solar energy is converted into electricity and thermal energy simultaneously using hot water or air together with electricity. This dual use saves a significant amount of energy and officially fights greenhouse gases. Different cooling techniques have been proposed in the literature for improving the overall performance of the PV/T systems; employing different types of agents including nanofluids and phase change materials. Hydrogen is the lightest and most abundant element in the universe and has later turned into a flexible energy carrier for transportation and other industrial applications. Issues, including the processes of Hydrogen manufacturing, preservation as well as some risks act as barriers. This paper provides an analysis of several recent publications on the efficiency of using PV/T technology in the process of green hydrogen production and indicates the potential for its increased efficiency as compared to conventional systems that rely on fossil fuels. Due to the effective integration of solar energy, the PV/T system can play an important role in the reduction of the levelized cost of hydrogen (LCOH) and hence play an important part in reducing the economic calculations of the decarbonized energy system.
Energy conservation, Energy industries. Energy policy. Fuel trade
Underwater sensor deployment in military applications requires high precision, yet existing robotic solutions often lack the maneuverability and adaptability required for complex aquatic environments. To address this gap, this study proposes a bio-inspired underwater robot modeled after the marine iguana, which exhibits effective crawling and swimming capabilities. The research aims to develop a compact, multi-functional robot capable of precise sensor deployment and environmental detection. The methodology integrates a biomimetic mechanical design—featuring leg-based crawling, tail-driven swimming, a deployable head mechanism, and buoyancy control—with a multi-sensor control system for navigation and data acquisition. Gait and trajectory planning are optimized using kinematic modeling for both terrestrial and aquatic locomotion. Experimental results demonstrate the robot’s ability to perform accurate underwater sensor deployment, validating its potential for military applications. This work provides a novel approach to underwater deployment robotics, bridging the gap between biological inspiration and functional engineering.
Currently, most studies on lactation-related traits and gene expression rely on invasive techniques to obtain mammary tissue. These methods are not only difficult to perform but also limit the availability of samples. Therefore, this study aimed to utilize whole transcriptome sequencing to investigate the gene expression profiles of Golden hamsters (Gh, n = 5) and Kunming mice (Km, n = 5). It compared the transcriptome expression between milk fat globules (MFG) and the mammary gland (MG), identified candidate genes and pathways associated with lactation traits, and assessed the potential of MFG as an effective alternative to MG. The data showed that a total of 21,360 genes were identified in the Gh group, with 66.5% of the mRNAs showing no differential expression between MG and MFG. In the Km group, a total of 44,248 genes were identified, with non-differentially expressed genes (NDEGs) accounting for 58.8%. Additionally, the majority of ncRNA data consisted of NDEGs. In both groups, approximately 80% of miRNA data were NDEGs. Notably, the proportion of NDEGs in circRNA data approached 100%. Enrichment analysis revealed that NDEGs from both groups were significantly enriched in several pathways, including the MAPK signaling pathway, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, and prolactin signaling pathway, all of which are closely associated with lactation traits and the lactation process. Furthermore, we identified various ncRNAs that regulate the expression of target genes either directly or indirectly, thereby influencing the lactation process. This study validates MFG as a reliable substitute for MG, with potential applications in improving dairy science. By identifying key genes and pathways, it provides new insights for optimizing genetic selection and breeding strategies. It also supports the improvement of dairy animal management practices.
Ahmed M. Zobaa, Hazem H. Abdelnabi, Rodan M. Reda
et al.
Abstract Corona discharge has been recognized for centuries, with sailors reporting the bluish glow of St. Elmo’s fire on ship masts during storms. In the early development of high-voltage engineering, researchers such as Townsend and Peek described the physical basis of this phenomenon as the ionization of air around a conductor when the electric field exceeds the strength of the surrounding medium. The result is a partial discharge that produces visible light, hissing sounds, ozone, and other reactive gases, while also creating radio interference and ultraviolet radiation. In modern transmission systems, these effects appear as wasted power, accelerated wear of insulators, shortened equipment lifetime, and environmental concerns. Although corona has been studied for decades, it continues to challenge the reliable and economical operation of high-voltage networks, particularly under changing weather conditions. This study investigates the phenomenon by analyzing its causes, effects, and mitigation strategies through a combination of theoretical modelling, simulation, and statistical analysis. Using MATLAB Simulink and Python, simulations were conducted under varying environmental conditions—including temperature, humidity, and pressure—as well as electrical parameters such as voltage and conductor design, using observed data to ensure practical relevance. Comparable data sources may be used in other national or regional contexts. Key statistical techniques, including linear and multiple regression, analysis of variance (ANOVA), t-tests, and Monte Carlo simulations, were applied to determine the most influential factors affecting corona discharge losses. Results confirmed that higher voltage levels and unfavorable environmental conditions significantly increase corona loss, while increased conductor spacing and the use of corona rings emerged as the most effective mitigation strategies. An economic analysis based on probabilistic modelling estimated potential annual savings of up to 455 million Egyptian pounds (EGP) for the Egyptian grid, serving as a representative case study. The analytical framework is general and can be applied to other national transmission systems with appropriate data. The findings offer data-driven insights for improving transmission efficiency, minimizing power losses, and enhancing the overall reliability and cost-effectiveness of high-voltage power systems.
The requirements for structural performance and seismic performance in the field of civil engineering are increasing. Traditional building structures have certain limitations in extreme conditions such as earthquakes. Therefore, this study discusses the design of modular bi-directional load-bearing and energy dissipating joints in the context of intelligent construction to improve the seismic performance of buildings. The study designs vertical joints and bi-directional joints, and the test results show that the hysteresis curve of the joints is hump-shaped, exhibiting excellent plastic deformation and energy dissipation performance. The introduction of oblique stiffening ribs in the vertical joints significantly improves the load-bearing capacity, and there is no significant decrease in load-bearing capacity when loaded to approximately 32 mm. The maximum energy dissipation coefficient of vertical joint specimen 1 is 1.485. For specimen 2, the maximum values is 1.801, and for the bi-directional joints, the maximum values is 2.156, demonstrating excellent energy dissipation capability. In conclusion, this research is of great significance for the combination of modern building engineering technology and intelligent construction, providing strong support for the seismic performance and overall safety of building structures.
Traditional internal support systems for deep foundation pits often suffer from issues such as insufficient stiffness, excessive displacement, and large support areas. To address these problems, the authors developed a novel spatial steel joist internal support system. Based on a large-scale field model test, this study investigates the bearing characteristics of the proposed system in deep foundation pits. A stiffness formulation for the novel support system was analytically derived and experimentally validated through a calibrated finite element model. After validation with test results, the effects of different vertical prestressing forces on the structure were analyzed. The results indicate that the proposed system provides significant support in deep foundation pits. The application of both horizontal and vertical prestressing increases the internal forces within the support structure while reducing overall displacement. The numerical predictions of horizontal displacement, bending moment, and the axial force distribution of the main support, as well as their development trends, align well with the model test results. Moreover, increasing the prestressing force of the steel tie rods effectively controls the deformation of the vertical arch support and enhances the stability of the spatial structure. The derived stiffness formula shows a small error compared with the finite element results, demonstrating its high accuracy. Furthermore, the diagonal support increases the stiffness of the lower chord bar support by 28.24%.
Cohesin is a multi-subunit protein that plays a pivotal role in holding sister chromatids together during cell division. Sister chromatid cohesion 3 (SCC3), constituents of cohesin complex, is highly conserved from yeast to mammals. Since the deletion of individual cohesin subunit always causes lethality, it is difficult to dissect its biological function in both mitosis and meiosis. Here, we obtained scc3 weak mutants using CRISPR-Cas9 system to explore its function during rice mitosis and meiosis. The scc3 weak mutants displayed obvious vegetative defects and complete sterility, underscoring the essential roles of SCC3 in both mitosis and meiosis. SCC3 is localized on chromatin from interphase to prometaphase in mitosis. However, in meiosis, SCC3 acts as an axial element during early prophase I and subsequently situates onto centromeric regions following the disassembly of the synaptonemal complex. The loading of SCC3 onto meiotic chromosomes depends on REC8. scc3 shows severe defects in homologous pairing and synapsis. Consequently, SCC3 functions as an axial element that is essential for maintaining homologous chromosome pairing and synapsis during meiosis.
For the project of pipe jacking in cohesionless soil, it is key to determine the vertical load on jacked pipe so as to predict the jacking force accurately. In this paper, a new parabolic soil arching model was proposed to calculate the vertical load on jacked pipe. This proposed analytical model was composed of parabolic soil arching zone, parabola-typed collapse zone and friction arch zone. Combined with existing literature, the key parameters (i.e., height of parabolic soil arching, horizontal pressure coefficient and width and height of friction arch) were determined. In addition, considering that the trajectory of major stress is parabola, the formula of horizontal pressure coefficient was deduced in the friction arch. The parabolic soil arching zone is assumed as a three-hinged arch with reasonable arch axis, and the formula of load transfer was derived considering the transition effect of parabolic soil arching. The results of experiment, theoretical models and numerical model were adopted to verify the proposed analytical model. Finally, the influence of the key parameters on the vertical load on jacked pipe were also discussed in detail. This work provides a meaningful reference for evaluating the vertical load on jacked pipe for design of pipe jacking.
Engineering geology. Rock mechanics. Soil mechanics. Underground construction
Kristen Gillespie-Lynch, Kristen Gillespie-Lynch, Eliana Grossman
et al.
IntroductionAutistic people face systemic barriers to fair employment. Informal learning may promote the self-determination transition-age autistic youth need to overcome and/or transform these barriers. This report focuses on the iterative process of developing video game design workshops guided by feedback from autistic students about instructional strategies they found engaging. This study is part of a three-year-long NSF-funded program of research that seeks to empower autistic youth to move toward successful careers by teaching educators how to more effectively guide them.MethodsIn the Summer of 2021, educators at an award-winning NYC-based, not-for-profit, education program, Tech Kids Unlimited (TKU) collaborated with researchers, including autistic students, to iteratively develop and assess two online game design workshops for transition-age autistic youth. Participants selected which workshop they were available for (Workshop 1: n = 18; M age = 16.72 years; Workshop 2: n = 16; M age = 16.56 years). Students in Workshop 2 had more varied support needs and were less motivated to learn video game design than students in Workshop 1. Students completed assessments before and after each workshop and rated their interest in specific workshop activities after each activity. Guided by data from Workshop 1, we revised instructional strategies before conducting Workshop 2.ResultsWe found little evidence for our hypothesis that attentional style would impact educational engagement. However, video game design self-efficacy and self-determination were often positively associated with engagement. Two industry speakers, one of whom was autistic, were among the highest-rated activities. As hypothesized, video game design self-efficacy and self-determination (and unexpectedly) spatial planning improved from pre- to post-test following Workshop 1. Despite our efforts to use what we learned in Workshop 1 to improve in Workshop 2, Workshop 2 did not lead to significant improvements in outcomes. However, students highlighted instructional strategies as a strength of Workshop 2 more often than they had for Workshop 1. Educators highlighted the importance of group “temperature checks,” individualized check-ins, social–emotional support for students and educators, and fostering a positive atmosphere.DiscussionFindings suggest that interactive multimodal activities, stimulating discussions, and opportunities to engage with neurodivergent industry professionals may engage and empower diverse autistic youth.
Dhanalekshmi Prasad Yedurkar, Shilpa P. Metkar, Fadi Al-Turjman
et al.
A novel approach for multichannel epilepsy seizure classification which will help to automatically locate seizure activity present in the focal brain region was proposed. This paper suggested an Internet of Things (IoT) framework based on a smart phone by utilizing a novel feature termed multiresolution critical spectral verge (MCSV), based on frequency-derived information for epileptic seizure classification which was optimized using a flower pollination algorithm (FPA). A wireless sensor technology (WSN) was utilized to record the electroencephalography (EEG) signal of epileptic patients. Next, the EEG signal was pre-processed utilizing a multiresolution-based adaptive filtering (MRAF) method. Then, the maximal frequency point at which the power spectral density (PSD) of each EEG segment was greater than the average spectral power of the corresponding frequency band was computed. This point was further optimized to extract a point termed as critical spectral verge (CSV) to extract the exact high frequency oscillations representing the actual seizure activity present in the EEG signal. Next, a support vector machine (SVM) classifier was used for channel-wise classification of the seizure and non-seizure regions using CSV as a feature. This process of classification using the CSV feature extracted from the MRAF output is referred to as the MCSV approach. As a final step, cloud-based services were employed to analyze the EEG information from the subject’s smart phone. An exhaustive analysis was undertaken to assess the performance of the MCSV approach for two datasets. The presented approach showed an improved performance with a 93.83% average sensitivity, a 97.94% average specificity, a 97.38% average accuracy with the SVM classifier, and a 95.89% average detection rate as compared with other state-of-the-art studies such as deep learning. The methods presented in the literature were unable to precisely localize the origination of the seizure activity in the brain region and reported a low seizure detection rate. This work introduced an optimized CSV feature which was effectively used for multichannel seizure classification and localization of seizure origination. The proposed MCSV approach will help diagnose epileptic behavior from multichannel EEG signals which will be extremely useful for neuro-experts to analyze seizure details from different regions of the brain.
Shafiq Ahmad, N. Ameer Ahammad, Muhammad Naveed Khan
et al.
An investigation of an axisymmetric mixed convective boundary layer flow of silver-titanium dioxide/water (Ag−TiO2/H2O) hybrid nanofluid towards vertically and rotating stretching cylinder with entropy generation is conducted. The Cattaneo-Christov theory and joule heating effect are used to analyze the features of thermal energy. Moreover, the magnetic impact and convective boundary conditions on the vertical surface also considered in the current investigation. The developing equations for momentum, energy and entropy generation are modelled and by the usage of similarity variables to transform into the system of nonlinear ordinary differential equations (ODEs). The solutions of nonlinear ODEs are obtained numerically with the assistance of BVP4C MATLAB built-in scheme. The graphical consequences and relevant physical reasoning regarding the velocity, temperature, and concentration profiles are discussed. It is noteworthy that strong estimation of buoyancy ratio and mixed convection parameter enhances axial velocity, but the swirl velocity is diminished. The fluid temperature and concentration both are diminished due to thermal and solutal stratification effects. It is also seen that thermal Biot and Eckert numbers enhance the temperature distribution. Further, the Reynold number improves entropy generation.
Benedikt Reick, Anja Konzept, André Kaufmann
et al.
Due to increasing sales figures, the energy consumption of battery-electric vehicles is moving further into focus. In addition to efficient driving, it is also important that the energy losses during AC charging are as low as possible for a sustainable operation. In many situations it is not possible or necessary to charge the vehicle with the maximum charging power e.g., in apartment buildings. The influence of the charging mode (number of phases used, in-cable-control-box or used wallbox, charging current) on the charging efficiency is often unknown. In this work, the energy consumption of two electric vehicles in the Worldwide Harmonized Light-Duty Vehicles Test Cycle is presented. In-house developed measurement technology and vehicle CAN data are used. A detailed breakdown of charging losses, drivetrain efficiency, and overall energy consumption for one of the vehicles is provided. Finally, the results are discussed with reference to avoidable CO<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mrow></mrow><mn>2</mn></msub></semantics></math></inline-formula> emissions. The charging losses of the tested vehicles range from 12.79 to 20.42%. Maximum charging power with three phases and 16 A charging current delivers the best efficiencies. Single-phase charging was considered down to 10 A, where the losses are greatest. The drivetrain efficiency while driving is 63.88% on average for the WLTC, 77.12% in the “extra high” section and 23.12% in the “low” section. The resulting energy consumption for both vehicles is higher than the OEM data given (21.6 to 44.9%). Possible origins for the surplus on energy consumption are detailed. Over 100,000 km, unfavorable charging results in additional CO<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mrow></mrow><mn>2</mn></msub></semantics></math></inline-formula> emissions of 1.24 t. The emissions for an assumed annual mileage of 20,000 km are three times larger than for a class A+ refrigerator. A classification of charging modes and chargers thus appears to make sense. In the following work, efficiency improvements in the charger as well as DC charging will be proposed.
Mechanical engineering and machinery, Machine design and drawing
Nicholas Embleton, Janet Berrington, Stephen Cummings
et al.
Background: Preterm infants have high rates of morbidity, especially from late-onset sepsis and necrotising enterocolitis. Lactoferrin is an anti-infective milk protein that may act through effects on gut bacteria, metabolites and epithelial cell function. The impact of supplemental lactoferrin in reducing late-onset sepsis was explored in the Enteral LactoFerrin In Neonates (ELFIN) trial. Objectives: The Mechanisms Affecting the Gut of Preterm Infants in Enteral feeding (MAGPIE) study was nested within the ELFIN trial and aimed to determine the impact of lactoferrin on gut microbiota and bacterial function, and changes preceding disease onset. We aimed to explore impacts on the stool bacteria and faecal/urinary metabolome using gas and liquid chromatography–mass spectrometry, and explore immunohistological pathways in resected tissue. Methods: Preterm infants from 12 NHS hospitals were enrolled in the study, and daily stool and urine samples were collected. Local sample collection data were combined with ELFIN trial data from the National Perinatal Epidemiology Unit, Oxford. The longitudinal impact of lactoferrin in healthy infants was determined, and samples that were collected before disease onset were matched with samples from healthy control infants. Established, quality-controlled 16S ribonucleic acid, gas chromatography–mass spectrometry and liquid chromatography–mass spectrometry analyses were conducted. Validated databases and standardised workflows were used to identify bacteria and metabolites. Tissue samples from infants undergoing surgery and matched controls were analysed. Results: We recruited 479 preterm infants (mean gestation of 28.4 ± 2.3 weeks) and collected > 33,000 usable samples from 467 infants. 16S ribonucleic acid bacterial analysis was conducted on samples from 201 infants, of whom 20 had necrotising enterocolitis and 51 had late-onset sepsis, along with samples from healthy matched controls to explore longitudinal changes. The greatest change in relative bacterial abundance over time was observed in Staphylococcus, which decreased from 42% at aged 7–9 days to only 2% at aged 30–60 days (p < 0.001). Small but significant differences in community composition were observed between samples in each ELFIN trial group (R2 = 0.005; p = 0.04). Staphylococcus (p < 0.01), Haemophilus (p < 0.01) and Lactobacillus (p = 0.01) showed greater mean relative abundance in the placebo group than in the lactoferrin group. Gas chromatography–mass spectrometry and liquid chromatography–mass spectrometry analyses showed that lactoferrin had limited impact on the metabolome. Liquid chromatography–mass spectrometry showed significant metabolite differences between necrotising enterocolitis or late-onset sepsis infants and healthy controls. The resected gut tissue analysis revealed 82 differentially expressed genes between healthy and necrotic tissue. Limitations: Although we recruited a large number of infants, collecting daily samples from every infant is challenging, especially in the few days immediately preceding disease onset. Conclusion: We conducted a large mechanistic study across multiple hospital sites and showed that, although lactoferrin significantly decreased the level of Staphylococcus and other key pathogens, the impact was smaller than those of other clinical variables. Immunohistochemistry identified multiple inflammatory pathways leading to necrotising enterocolitis and showed that the use of NHS pathology archive tissue is feasible in the context of a randomised controlled trial. Future work: We observed significant changes in the stool and urinary metabolome in cases preceding late-onset sepsis or necrotising enterocolitis, which provide metabolic targets for a future mechanistic and biomarker study. Trial registration: Current Controlled Trials ISRCTN12554594. Funding: This project was funded by the Efficacy and Mechanism Evaluation (EME) programme, a Medical Research Council (MRC) and National Institute for Health Research (NIHR) partnership. This will be published in full in Efficacy and Mechanism Evaluation; Vol. 8, No. 14. See the NIHR Journals Library website for further project information.
Currently, effective quality management of manufactured products is a factor determining the development of manufacturing companies. However, the identification of the source of non-compliance and the analysis of its causes are sometimes underestimated and are not followed by appropriate methodologies. The study aimed to streamline and improve the production process of aluminium pistons for passenger cars by solving the problem related to a significant number of non-compliant products. The analysis of types of nonconformities identified through penetration testing was performed. The use of histogram, brainstorming session and Pareto-Lorenz diagram was proposed, which allowed identifying the causes of the problem. The presented solution shows the practical effectiveness of a sequence of selected instruments to solve production problems. The proposed sequence of methods can be implied in other qualitative analyses in different companies.
Machine design and drawing, Engineering machinery, tools, and implements
Triploid breeding is a central way to improve growth traits, timber quality, and stress resistance in Populus. In the present study, the morphology and viability of colchicine-induced 2n pollen, triploid production by crossing induced 2n pollen, and identification of genetic constitution of colchicine-induced 2n pollen were conducted in Populus canescens based on optimizing technology for inducing chromosome doubling in pollen. We found that the meiotic stage, injection time, and the interaction between the meiotic stage and injection time had highly significant effects on the 2n pollen production rate. The most effective treatment for inducing 2n pollen was to give 11 injections of 0.5% colchicine solution when pollen mother cells (PMCs) were at the pachytene stage. The highest 2n pollen production rate was 30.27 ± 8.69%. Colchicine occasionally affected ectexine deposition, and some narrow furrows were detected in the ectexine structure. However, no significant difference was observed in the pollen germination rate between natural 2n pollen and colchicine-induced 2n pollen. Moreover, 5 triploids derived from FDR-type 2n pollen were generated by crossing induced 2n pollen, suggesting that colchicine does not eliminate the function of colchicine-induced 2n pollen. However, slower growth of 2n pollen tubes was responsible for a lower triploid production rate.
[Introduction] To supply energy for industrial users in an economical and efficient way, an energy supply unit model in distributed energy system (DES) is established based on coupling characteristics of electric and thermal loads, and optimal operation strategy is proposed. [Method] Taking an industrial park in Guangzhou as the research object, combined with the actual load data, the optimum parameters were reasonably determined, annual power generation, gas consumption and energy efficiency were calculated, and the impact of load increment was studied. [Result] The results show that the start-up thermal load of unit has a great influence on the annual power generation of DES. With the optimized operation strategy, the annual power generation can be increased by 18.7%, and the self-power supply ratio of the park can be increased. The energy efficiency is more than 85%. [Conclusion] The optimal operation strategy is correct and effective. It can be applied to the optimization of thermo-electric coupled DES, effectively enhance the energy supply of DES with high energy efficiency.
Computer Aided Engineering (CAE) is commonly used in modern design of the various types of structures. There are two main issues/aspects that should be consider while using CAE in Geotechnics: the basic theory and material model. The paper deals with a problem of choosing the proper constitutive relationships which according to the authors are equally important in obtaining correct and reasonable results. This problem is illustrated by an example of dynamic calculations of fully saturated non-cohesive soils where liquefaction phenomenon is most likely to occur.
Engineering geology. Rock mechanics. Soil mechanics. Underground construction