The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented generation (RAG) technologies show potential to enhance their clinical applicability. This study reviewed RAG applications in medicine. We found that research primarily relied on publicly available data, with limited application in private data. For retrieval, approaches commonly relied on English-centric embedding models, while LLMs were mostly generic, with limited use of medical-specific LLMs. For evaluation, automated metrics evaluated generation quality and task performance, whereas human evaluation focused on accuracy, completeness, relevance, and fluency, with insufficient attention to bias and safety. RAG applications were concentrated on question answering, report generation, text summarization, and information extraction. Overall, medical RAG remains at an early stage, requiring advances in clinical validation, cross-linguistic adaptation, and support for low-resource settings to enable trustworthy and responsible global use.
In general relativity, the strong equivalence principle is underpinned by a geometrical interpretation of fields on spacetime: all fields and bodies probe the same geometry. This geometric interpretation implies that the parallel transport of all spacetime tensors and spinors is dictated by a single affine connection. Can something similar be said about gauge theory? Agreed, in gauge theory different symmetry groups rule the interactions of different types of charges, so we cannot expect to find the same kind of universality found in the gravitational case. Nonetheless, the parallel transport of all the fields that are charged under the same symmetry group is dictated by a single 'gauge connection', and they all transform jointly under a gauge transformation. Is this kind of 'restricted universality' as geometrically underpinned as in general relativity? Here I argue that it is. The key difference is that the gauge geometry concerns 'internal', as opposed to 'external', spaces. The gauge symmetry of the standard model is thus understood as merely the automorphism group of an internal geometric structure -- $C^3\otimes C^2\otimes C^1$ endowed with an orientation and canonical inner product -- in the same way as spacetime symmetries (such as Poincare transformations), are understood as the automorphism group of an external geometric structure (respectively, a Minkowski metric). And the Ehresmann connection can then be understood as determining parallelism for this internal geometry.
We show that with an internal SO(3) symmetric triplet of Higgs fields, the conserved quantity associated with this internal SO(3) symmetry leads to spontaneous symmetry breaking giving the Higgs field a mass.
This work is devoted to investigating a compressible fluid system with low stratification, which is driven by fast acoustic waves and internal waves. The approximation using a soundproof model is justified. More precisely, the soundproof model captures the dynamics of both the non-oscillating mean flows and the oscillating internal waves, while filters out the fast acoustic waves, of the compressible system with or without initial acoustic waves. Moreover, the fast-slow oscillation structure is investigated.
A. P. Misra, Animesh Roy, Debjani Chatterjee
et al.
The theory of low-frequency internal gravity waves (IGWs) is readdressed in the stable stratified weakly ionized Earth's ionosphere. The formation of dipolar vortex structures and their dynamical evolution, as well as, the emergence of chaos in the wave-wave interactions are studied both in presence and absence of the Pedersen conductivity. The latter is shown to inhibit the formation of solitary vortices and the onset of chaos.
David F. Rentería-Estrada, Roger J. Hernández-Pinto, German F. R. Sborlini
Achieving a precise description of the internal structure of hadrons is a hard task, since there are several bottlenecks to obtain theoretical predictions starting from first principles. In order to complement the highly-accurate experiments, it is necessary to use ingenious strategies to impose constraints from the theory side. In this article, we describe how photons can be used to unveil the internal structure of hadrons. Using up-to-date PDFs and FFs, we explore how to describe NLO QCD plus LO QED corrections to hadron plus photon production at colliders.
The monogamy relations of entanglement are highly significant. However, they involve only amounts of entanglement shared by different subsystems. Results on monogamy relations between entanglement and other kinds of correlations, and particularly classical correlations, are very scarce. Here we experimentally observe a tradeoff relation between internal quantum nonseparability and external total correlations in a photonic system and found that even purely classical external correlations have a detrimental effect on internal nonseparability. The nonseparability we consider, measured by the concurrence, is between different degrees of freedom within the same photon, and the external classical correlations, measured by the standard quantum mutual information, are generated between the photons of a photon pair using the time-bin method. Our observations show that to preserve the internal entanglement in a system, it is necessary to maintain low external correlations, including classical ones, between the system and its environment.
Measurability with respect to ideals is tightly connected with absoluteness principles for certain forcing notions. We study a uniformization principle that postulates the existence of a uniformizing function on a large set, relative to a given ideal. We prove that for all $σ$-ideals $I$ such that the ideal forcing $\mathbb{P}_I$ of Borel sets modulo $I$ is proper, this uniformization principle is equivalent to an absoluteness principle for projective formulas with respect to $\mathbb{P}_I$ that we call internal absoluteness. In addition, we show that it is equivalent to measurability with respect to $I$ together with $1$-step absoluteness for the poset $\mathbb{P}_I$. These equivalences are new even for Cohen and random forcing and they are, to the best of our knowledge, the first precise equivalences between regularity and absoluteness beyond the second level of the projective hierarchy.
We investigate the dynamics of a microelectromechanical (MEMS) self-sustained oscillator supporting multiple resonating and interacting modes. In particular, the interaction of the first four flexural modes along with the first torsional mode are studied, whereby 1:2, 1:3, and 2:1 internal resonances occur. Even and odd modes are induced to couple by breaking the longitudinal symmetry of the structure. Self-oscillations are induced in the second flexural mode via a gain-feedback loop, thereafter its frequency is pulled into a commensurate frequency ratio with the other modes, enabling the oscillator to act as a driver/pump for four modes simultaneously. Thus, by leveraging multiple internal resonances, a five modes frequency-locked comb is generated.
We show a relation between entanglement and correlations of any form. The internal entanglement of a bipartite system, and its correlations with another system, limit each other. A measure of correlations, of any nature, cannot increase under local operations. Examples are the entanglement monotones, the mutual information, that quantifies total correlations, and the Henderson-Vedral measure of classical correlations. External correlations, evaluated by such a measure, set a tight upper bound on the internal entanglement that decreases as they increase, and so does quantum discord.
Yvan Dossmann, Florence Pollet, Philippe Odier
et al.
The energy pathways from propagating internal waves to the scales of irreversible mixing in the ocean are not fully described. In the ocean interior, the triadic resonant instability is an intrinsic destabilization process that may enhance the energy cascade away from topographies. The present study focuses on the integrated impact of mixing processes induced by a propagative normal mode-1 over long term experiments in an idealised setup. The internal wave dynamics and the evolution of the density profile are followed using the light attenuation technique. Diagnostics of the turbulent diffusivity $K_{T}$ and background potential energy $BPE$ are provided. Mixing effects result in a partially mixed layer colocated with the region of maximum shear induced by the forcing normal mode. The maximum measured turbulent diffusivity is 250 times larger than the molecular value, showing that diapycnal mixing is largely enhanced by small scale turbulent processes. Intermittency and reversible energy transfers are discussed to bridge the gap between the present diagnostic and the larger values measured in Dossmann et al, Experiments in Fluids, 57(8), 132 (2016). The mixing efficiency $η$ is assessed by relating the $BPE$ growth to the linearized $KE$ input. One finds a value of $Γ=12-19\%$ larger than the mixing efficiency in the case of breaking interfacial wave. After several hours of forcing, the development of staircases in the density profile is observed. This mechanism has been previously observed in experiments with weak homogeneous turbulence and explained by argument. The present experiments suggest that internal wave forcing could also induce the formation of density interfaces in the ocean.
In this paper we are concerned with a nonlocal system to model the propagation of internal waves in a two-layer interface problem with rigid lid assumption and under a Boussinesq regime for both fluids. The main goal is to investigate aspects of well-posedness of the Cauchy problem for the deviation of the interface and the velocity, as well as the existence of solitary wave solutions and some of their properties.
The search is now on for, new materials that can be used for ionic stripping. Materials that maximize the stripping of the structural ion are important for conducting experiments with quark-gluon plasma. Although this paper is a theoretical study, it offers practical application, in heavy-ion accelerators, of the new effect of collision multiplicity with high-energy ions interacting with polyatomic targets. It is shown that internal nanostructured targets in which the collision multiplicity effect is manifested can more efficiently strip out structural ions compared to standard internal targets for stripping. A target consisting of oriented nano-tubes with the $C_{240}$ chirality (10,0) is considered as an example. A comparison with the stripping process on a carbon target with the same number of misaligned atoms in a unit of volume $C$ is provided.
Pavlo V. Bilous, Georgy A. Kazakov, Iain D. Moore
et al.
The process of internal conversion from excited electronic states is investigated theoretically for the case of the vacuum-ultraviolet nuclear transition of $^{229}{\mathrm Th}$. Due to the very low transition energy, the $^{229}{\mathrm Th}$ nucleus offers the unique possibility to open the otherwise forbidden internal conversion nuclear decay channel for thorium ions via optical laser excitation of the electronic shell. We show that this feature can be exploited to investigate the isomeric state properties via observation of internal conversion from excited electronic configurations of ${\mathrm Th}^+$ and ${\mathrm Th}^{2+}$ ions. A possible experimental realization of the proposed scenario at the nuclear laser spectroscopy facility IGISOL in Jyväskylä, Finland is discussed.
Models for the internal composition of Dense Compact Stars are reviewed as well as macroscopic properties derived by observations of relativistic processes. Modeling of pure neutron matter Neutron Stars is presented and crust properties are studied by means of a two fluid model.
We introduce driven exclusion processes with internal states that serve as generic transport models in various contexts, ranging from molecular or vehicular traffic on parallel lanes to spintronics. The ensuing non-equilibrium steady states are controllable by boundary as well as bulk rates. A striking polarization phenomenon accompanied by domain wall motion and delocalization is discovered within a mesoscopic scaling. We quantify this observation within an analytic description providing exact phase diagrams. Our results are confirmed by stochastic simulations.