Towards Understanding the Relationship Between Personality Types and Homeopathic Remedies in an Integrative Health Approach
Esra Tosun, Ali Timucin Atayoglu
<b>Objective:</b> This study aims to explore the integration of Enneagram personality types with homeopathic prescribing by evaluating the relationship between personality traits and the corresponding homeopathic remedies, enhancing individualized care through an analysis of the possible mind rubrics. <b>Method:</b> Personality traits from the dynamic Enneagram model were mapped to corresponding mental–emotional traits. These traits were matched to the relevant possible rubrics in the Synthesis Treasure Edition repertory, using Radar Opus software. A total of 36 analyses were conducted across nine personality types. The frequency distribution (%) of remedies appearing in the top five rankings was analyzed, identifying remedies corresponding to the highest number of rubrics. <b>Results:</b> Forty rubrics were used in the repertorization, with duplicate rubrics counted only once, and nine different remedies were identified with a value of four points. The frequency distribution showed that polychrest remedies appeared most frequently in the top five rankings across all 36 analyses, indicating a relationship between certain remedies and personality traits. <b>Conclusions:</b> Integrating Enneagram personality traits into homeopathic prescribing could enhance individualized care by providing additional insights for remedy selection, alongside the traditional approaches that are commonly used, such as case analysis using the totality of symptoms. Further research is needed to refine and validate this approach.
Retraction Note: Wound healing potentials of herbal ointment containing Calendula officinalis Linn. on the alteration of immunological markers and biochemical parameters in excision wounded animals
Shobana Gunasekaran, Agnel Arul John Nayagam, Rameshkannan Natarajan
Body Acupuncture Conjunction with Rehabilitation for Upper Limb Improves Motor Functions in Children with Spastic Hemiplegic Cerebral Palsy: A Pilot Study
Hui Wang MS, Yu Du MS, Tong Chen BS
et al.
Objective Aimed to investigate the effectiveness of body acupuncture on motor function of the upper limb in children with spastic hemiplegic cerebral palsy (CP) conjunction with rehabilitation program. Design The study is a randomized controlled experimental trial. Children with CP were randomly divided into the acupuncture group (body acupuncture with rehabilitation) and the rehabilitation group. The muscle volume difference between the upper limbs, the fine motor scores of the Peabody developmental motor scale-2 (PDMS-FM) and the surface electromyography (SEMG) parameter-root mean square (RMS)-on upper limb muscles (biceps brachii, radial wrist extensors and pronator teres) of both groups were measured before and after a 12-week treatment. Results 37 children completed the study. In the two groups, differences in muscle volume, PDMS-FM scores and RMS values (biceps brachii, radial wrist extensors and pronator teres) were significantly improved, except PDMS-FM score difference and difference of RMS values (biceps brachii, radial wrist extensors and pronator teres) between the upper limbs in the rehabilitation group. Comparison post-treatment/pre-treatment change for two groups showed significant difference in affected upper limb PDMS-FM total score, PDMS-FM score difference between the upper limbs, affected upper limb RMS values and RMS value difference between the upper limbs in favor of the acupuncture group. Conclusion Our preliminary research indicates that body acupuncture therapy combined with rehabilitation may be more effective than rehabilitation alone, further improving muscle strength of affected upper limb and possibility of bimanual coordination in children with spastic hemiplegic CP.
Other systems of medicine, Homeopathy
Homeopathy for Heteropathy: FSS and Its Components for the Treatment of Alzheimer&rsquo;s Disease and Endometriosis
Yu Y, Sun T, Zhang J
et al.
Yang Yu,1 Tiantian Sun,2 Jingyu Zhang,2 Songquan Wu,1 Xin Tong,3 Fazheng Zhao,3 Xin Fu1 1School of Medicine, Lishui University, Lishui, 323000, Zhejiang Province, People’s Republic of China; 2School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, 150040, Heilongjiang Province, People’s Republic of China; 3Zhejiang University of Traditional Chinese Medicine, Hangzhou, 310000, Zhejiang Province, People’s Republic of ChinaCorrespondence: Xin Fu, Email fu19511317872@sina.comAbstract: Foshou San (FSS), which is a traditional Chinese compound formula. So far, a variety of components have been isolated and identified from its complex composition. These findings endow it with diverse pharmacological activities. According to a number of studies, FSS has significant efficacy in treating cognitive impairment in Alzheimer’s disease (AD) and gynecological diseases like Endometriosis (EMs). Behind these curative effects, the specific chemical components of FSS play a crucial role. In this paper, the research progress of FSS in phytochemistry, pharmacology and pharmacokinetics are reviewed. Through comprehensive analysis of apoptosis regulation, oxidative stress and inflammation, ferroptosis, bile acid and intestinal flora, we further demonstrate the feasibility and potential of FSS in treating of AD and EMs. This not only reveals the potential mechanism of FSS, but also provides valuable experience and enlightenment for future research and application in related fields.Keywords: Foshou San, component, alzheimer’s disease, endometriosis, homeopathy for heteropathy
Therapeutics. Pharmacology
Retraction Note: Acute and sub-acute (30-day) toxicity studies of Aegialitis Rotundifolia Roxb., leaves extract in Wistar rats: safety assessment of a rare mangrove traditionally utilized as pain antidote
Debjit Ghosh, Sumanta Mondal, K. Ramakrishna
Evaluating the anti-urolithiasis potential of Ficus religiosa seed GC MS evaluated phytoconstituents based on their in-vitro antioxidant properties and in-silico ADMET and molecular docking studies
Felicity Pinipay, Rajesh Rokkam, Satyanarayana Botcha
et al.
Abstract Background Urolithiasis, the deposit of stones in the urinary tract is a pertinent clinical issue in daily practice that imposes a burden on the human health system. Ficus religiosa plant has historically been useful in preventing urolithiasis. There is currently no information on phytochemical profiling that specifies the precise phytochemicals in the seed that are active against urolithiasis. Methods F. religiosa seeds were extracted with different solvents in increasing order of their polarity by Soxhlet extraction. All the extracts were evaluated for their antioxidant potential. GC–MS profiling of the most potent antioxidant F. religiosa seed extract was done to evaluate the phytoconstituents. To evaluate the pharmacokinetics and drug-likeness properties of these compounds in silico ADMET analysis was done. To comprehend the binding potential of the best ADMET evaluated phytochemicals contained in the F. religiosa seed extract against the several protein targets (matrix metalloproteinases (MMP-2, MMP-9), and Human calcium-sensing receptor (CaSR)) and antioxidant enzymes (Glutathione S-transferase (GST), glutathione-disulfide reductase (GR), glutathione peroxidase (GPX), and superoxide dismutase (SOD)) involved in urolithiasis, multi targets based virtual screening tests were done using Autodock Vina tool. Results GC–MS profiling revealed the presence of 53 different compounds. Of all these compounds, based on ADMET analysis 2-Methoxy-4-vinylphenol; 3,5-Di-tert-butylphenol; diethyl benzene-1,2-dicarboxylate; 4-hydroxy-3,5-dimethoxybenzaldehyde; 2-methoxy-4-prop-2-enylphenol; and bis (2-methyl propyl) benzene-1,2-dicarboxylate were found to have best pharmacokinetics and drug-likeness properties. In the autodocking studies, 3,5-Di-tert-butyl phenol is proved to be the best of all in terms of binding energies with the selected targets. Conclusion The findings of this study suggest a framework for employing F. religiosa seed ethyl acetate extract as a potent herbal treatment for urolithiasis.
The Anti-Inflammatory Activity of <i>Viscum album</i>
Marcello Nicoletti
The therapeutic story of European mistletoe (<i>Viscum album</i> L.) presents a seesawing profile. In ancient times, this hemiparasitic plant was considered a panacea and even to be endowed with exceptional beneficial properties. In more recent times, despite its multiple uses in traditional medicines, some parts of the plant, in particular the berries, were considered poisonous and dangerous, including concerns of cytotoxicity, which spread serious suspicion on its medicinal utility. However, since the last century, medical interest in mistletoe has come back in force due to its utilization in clinical cancer treatments, based on its selective action on tumor cells. In Central Europe, the hydro-alcoholic extracts of European mistletoe register a relevant and continuous utilization in anthroposophic medicine, which is a holistic system that includes the utilization of phytomedicinal substances. In Switzerland and Germany, most physicians and patients use these products as complementary therapy in oncological treatments. However, despite its increasing use in this field, the results of mistletoe’s use are not always convincing, and other aspects have appeared. Nowadays, products that contain mistletoe are utilized in several fields, including diet, phytotherapy, veterinary medicine and homeopathy, but in particular in cancer therapies as coadjuvant factors, in consideration of several positive effects including effects in the improvement of quality-of-life conditions and reinforcement of the immune system. In this review, based on the understanding of the association between cancer and inflammation, we propose a relationship between these recent uses of mistletoe, based on its antioxidant properties, which are supported by phytochemical and pharmacological data. The unicity of mistletoe metabolism, which is a direct consequence of its hemiparasitism, is utilized as a key interpretation element to explain its biological properties and steer its consequent therapeutic uses.
Multidimensional perfectionism trends among various core and allied health care professionals in a major Indian metropolitan city of Western India
Vaibhav Kumar, Sushrut Anarase, Romi Jain
et al.
BACKGROUND: This exploratory study was done to assess the multidimensional perfectionism trends among various core and allied health care professionals in a major Indian metropolitan city of western India. Unlike other scales, here we considered both individual and intersubjective components of perfectionism by introducing three trait dimensions – self-oriented perfectionism, other-oriented perfectionism, and socially prescribed perfectionism.
MATERIALS AND METHODS: A cross-sectional descriptive type of study was conducted with total sample consisting of 500 participants with the main motive of evaluation and comparison of the multidimensional perfectionism among interns of the core and allied health care professionals from fields of medicine, dentistry, ayurveda, and homeopathy residing in the major Indian metropolitan cities of western India.
RESULTS: This study showed that under the self-oriented domain, highest mean score is of medical faculty (73.97). In other-oriented domain, dental (62.62) and homeopathy (62.38) professionals have almost similar mean. Lowest being of ayurveda (61.65) compared to the highest score of the medical fraternity (67.62). In the socially prescribed domain, medical professionals (65.53) have the highest mean though it is the lowest mean value of the medical faculty compared to other two domains. Chi-square test is applied to the data for the questions among all the three domains. Correlation has been deduced by applying Pearson's correlation to the collected data from the study. The degree of correlation between self-oriented with self-oriented is 1, self-oriented with other-oriented is 0.763, and that of self-oriented with socially oriented is 0.678.
CONCLUSION: Medical professionals scoring maximum in self-oriented perfectionism compared to other two domains reflect their extreme personal standards. Medical professionals are followed by dental professionals in self oriented perfectionism who are demanded of perfection in their routine practice. Ayurveda and homeopathy professionals scored better in other-oriented and socially prescribed perfectionism attributing to their sentiments of fulfilling the expectations and demands of others.
Special aspects of education, Public aspects of medicine
Integrative approach to fracture healing: A review
Ravi Kant Kaushik, Vasundhara Singh, Ramteerth Sharma
et al.
It is said that first sign of civilization in human history was a femur that had been broken and then healed with the care of the loved ones. Such deep is the association of mankind and fractures. Since time immemorial, fracture patients are taking varied therapies to enhance fracture healing. Some are evidence based, some are not. With renewed interest in complementary and alternative medicine; it becomes wise to make primary care physicians aware of the viewpoints of dietician, homeopathy doctor and an ayurveda doctor on the medicines prescribed by them for fracture cases. A physician should be aware of different treatment methodologies to have an intelligent discussion with a curious patient. Dieticians emphasize on a healthy balanced diet. Ayurveda physicians focus on shali rice and clarified butter; while homeopathy physicians vouch on Symphytum.
Internal medicine, Specialties of internal medicine
Alternative treatment of bovine mastitis
N. Mimoune, R. Saidi, O. Benadjel
et al.
Nora MIMOUNE*#, (Corresponding author, email: nora.mimoune@gmail.com), National high school of veterinary medicine, Algiers, Bab-Ezzouar, Algeria, Institute of veterinary Sciences, Laboratory of Biotechnologies related to animal Reproduction (LBRA), University of Blida 1, Algeria; Radhwane SAIDI#, Department of Agronomic Sciences, Faculty of Sciences, Laboratory of Biological and Agronomic Sciences, University of Laghouat, Algeria; Oumayma BENADJEL, National high school of veterinary medicine, Algiers, Bab-Ezzouar, Algeria; Djamel KHELEF, National high school of veterinary medicine, Algiers, Bab-Ezzouar, Algeria; Rachid KAIDI, Institute of veterinary sciences, Laboratory of Biotechnologies related to animal Reproduction (LBRA), university of Blida 1, Algeria #These authors have contributed equally in this work Abstract The treatment of mastitis is based mainly on the use of antibiotics. However, in recent times, an increase in resistance phenomena and the presence of residues in milk and their derivatives has been reported. Few studies have focused on the treatment of mastitis by homeopathy elsewhere or in Algeria. The objective of this current study aimed to clarify in particular the interest of homeopathy in the treatment of mastitis. The study was carried out on two dairy farms on a total of 14 cows located in Laghouat region (southern Algeria). Before the start of the experiment, a tolerance test was performed on two cull cows free from any apparent infection (except mastitis). Local and general reactions were noted at specific times. A total of 31 mammary quarters received 4 intramammary injections of a homeopathic preparation containing several natural products every 12h over 48h. A clinical examination and an analysis of the milk samples on D0, D7 and D14 were performed on all cows and the conclusion was made on the day 14. Data showed a very good tolerance to the homeopathic preparation and a 75% cure rate of the clinical mastitis. An improvement with a decrease in CMT score was also noted. In addition, healing rates of 51.85% for subclinical mastitis on D7 and 59.29% on D14 were also reported. Ultimately, homeopathy could, in some cases, represent an alternative to antibiotic therapy and bring an advantage to breeders. Further investigations should be performed in the future.
Physicochemical Investigations of Homeopathic Preparations: A Systematic Review and Bibliometric Analysis—Part 3
A. Tournier, Sandra Würtenberger, S. Klein
et al.
Objectives: In parts I and II of our review of physicochemical research performed on homeopathic preparations, we identified relevant publications and analyzed the data in terms of individual experiments, looking for the most promising techniques that were used in the past. In this third part, we analyze the results of the experiments seeking to extract information about the possible modes of action underpinning homeopathic preparations. Methods: We summarized the results from the 11 experimental areas previously introduced, extracting the general findings and trends. We also summarized the results in terms of specific research topics: aging, medium used for potentization, sample volume, temperature, material of potentization vessel, and, finally, the use of molecules to probe homeopathic samples. Results: We identified a number of effects that appear consistently throughout the data: Differences to controls seem to increase with: time, moderate temperature, small samples volume, and in ionic medium, whereas high temperatures seem to abolish differences to controls. Based on the present analysis, there is no consistent evidence to date for the nanoparticle hypothesis to explain specific homeopathic treatment effects. However, the quantum coherence domain hypothesis, the dynamic water cluster hypothesis, and the weak quantum theory are still contenders and need to be further assessed experimentally. Conclusions: The field requires further targeted experimentation to validate past findings reporting differences between homeopathic dilutions and controls, and to expand these findings by specifically testing the three main working hypotheses that are currently at hand.
Correction to: A randomized, open-label, multicentre, comparative study of therapeutic efficacy, preventive potential and tolerability of BNO 1030 extract, containing Althea root, Chamomile flowers, horsetail herb, walnut leaves, yarrow herb, oak bark, dandelion herb in the treatment of acute non-bacterial tonsillitis in children aged 6 to 18 years
Vasyl Popovych, Ivana Koshel, Oleksandr Malofiichuk
et al.
An amendment to this paper has been published and can be accessed via the original article.
Acute and sub-acute toxicity profile of crude extract and fractions of Gymnema sylvestre
Rofiyat Omolara Raji, Hadiza Lami Muhammad, Abdulkadir Abubakar
et al.
Abstract Background Gymnema sylvestre is a reputable medicinal plant commonly explore for the management of diabetes and other ailments in traditional medicine. In the present study, we investigated the phytochemical compositions and effect of crude extract, hexane, and ethyl-acetate fractions of Gymnema sylvestre on biochemical and hematological parameters of Wistar rats. Methods Albino rats were distributed randomly into a control group and nine treatment groups orally administered crude extract and fractions of Gymnema sylvestre (100, 300, and 600 mg/kg BW) for 21 days. Liver and kidney function indices, as well as hematological parameters, were monitored. Results Our results revealed that the crude methanol extract contains flavonoids (8.56 ± 0.50 mg/g), alkaloids (13.84 ± 0.67 mg/g), total phenol (1.98 ± 0.50 mg/g), saponins (23.85 ± 0.35 mg/g) and tannins (16.00 ± 0.34 mg/g). The crude methanol, ethyl acetate and n-hexane fractions of Gymnema sylvestre had LD50 greater than 5000 mg/kg BW in acute oral toxicity test. The extract and fractions at 300 and 600 mg/kg BW cause loss of body weight of the rats, significantly altered (p < 0.05) the levels of biochemical indices including the aspartate transaminases, alanine transaminase, alkaline phosphates, bilirubin, proteins, urea, creatinine, and white blood cells (WBC) counts when compared with the non-treated control. However, the extract and fractions at 100 mg/kg BW did not cause any significant (p > 0.05) alterations to the levels of biochemical and hematological parameters when compared with the non-treated control. Conclusion Gymnema sylvestre at sub-acute doses of 300 and 600 mg/kg BW could compromise the functional integrity of the rats’ liver and kidney. The study, therefore, suggested the use of Gymnema sylvestre for oral remedy at a dose of 100 mg/kg or below.
EFFICACY OF HOMOEOPATHIC MEDICINES IN CHRONIC LOW BACK PAIN: A CLINICAL STUDY
E. SivaRamiReddy., B. Adi
Homeopathic ligand-free palladium as a catalyst in the heck reaction. A comparison with a palladacycle.
André H. M. de Vries, Jan M. C. A. Mulders, J. Mommers
et al.
466 sitasi
en
Chemistry, Medicine
Physicochemical Investigations of Homeopathic Preparations: A Systematic Review and Bibliometric Analysis—Part 2
A. Tournier, S. Klein, Sandra Würtenberger
et al.
Objectives: In Part 1 of the review of physicochemical research performed on homeopathic preparations the authors identified relevant publications of sufficient reporting quality for further in-depth analysis. In this article, the authors analyze these publications to identify any empirical evidence for specific physicochemical properties of homeopathic preparations and to identify most promising experimental techniques for future studies. Methods: After an update of the literature search up to 2018, the authors analyzed all publications in terms of individual experiments. They extracted information regarding methodological criteria such as blinding, randomization, statistics, controls, sample preparation, and replications, as well as regarding experimental design and measurement methods applied. Scores were developed to identify experimental techniques with most reliable outcomes. Results: The publications analyzed described 203 experiments. Less than 25% used blinding and/or randomization, and about one third used adequate controls to identify specific effects of homeopathic preparations. The most promising techniques used so far are nuclear magnetic resonance (NMR) relaxation, optical spectroscopy, and electrical impedance measurements. In these three areas, several sets of replicated high-quality experiments provide evidence for specific physicochemical properties of homeopathic preparations. Conclusions: The authors uncovered a number of promising experimental techniques that warrant replication to assess the reported physicochemical properties of homeopathic preparations compared with controls. They further discuss a range of experimental aspects that highlight the many factors that need to be taken into consideration when performing basic research into homeopathic potentization. For future experiments, the authors generally recommend using succussed (vigorously shaken) controls, or comparing different homeopathic preparations with each other to reliably identify any specific physicochemical properties.
Medical Crowdfunding for Scientifically Unsupported or Potentially Dangerous Treatments
Ford Vox, K. Folkers, Angela Turi
et al.
This study identified fundraising campaigns for unsubstantiated treatments, such as homeopathic remedies for cancer and antibiotic therapy for chronic Lyme disease, on GoFundMe and other crowdfunding platforms.
Complementary and alternative medicine use in adults with autism spectrum disorder in Germany: results from a multi-center survey
Juliana Höfer, Falk Hoffmann, Inge Kamp-Becker
et al.
Abstract Background Complementary and Alternative Medicine (CAM) is widely used both in the general population and for the treatment of somatic and psychiatric disorders. Studies on CAM use among patients with autism spectrum disorder (ASD) have so far only focused on children and adolescents. The aim of this study was to investigate patterns of CAM use among adults with ASD. Methods A questionnaire survey concerning current and lifetime use of CAM was distributed to adults with ASD between November 2015 and June 2016. Participants diagnosed by experienced clinicians using the current diagnostic gold standard were recruited from four ASD outpatient clinics in Germany. Questionnaire data was then linked to supplementary clinical data. Results The final sample consisted of 192 adults (response: 26.8%) with a mean age of 31.5 years (80% male; diagnoses: Asperger’s syndrome (58%), childhood autism (27%), atypical autism (12%)). 45% of the respondents stated that they were currently using or had used at least one CAM modality in their life. Among the participants with lifetime CAM use, almost half had used two or more different types of CAM. Alternative medical systems (e.g. homeopathy, acupuncture) were most frequently used, followed by mind-body interventions (e.g. yoga, biofeedback, animal assisted therapy). Overall, 20% of respondents stated that they would like to try at least one listed CAM modality in the future. Conclusions This is the first study on CAM use in adults with ASD, demonstrating considerable CAM use in this population. Given the popularity of CAM, patients should be informed about the effectiveness and potentially dangerous side effects of CAM treatments, as evidence for the majority of CAM methods in ASD is still limited.
Establishment of Pharmacopoeial Quality Standards for the State Pharmacopoeia of the Russian Federation
E. Sakanyan, T. B. Shemeryankina, I. Osipova
et al.
In Vivo Evaluation of –Based Indian Traditional Formulation (), Against Chikungunya Virus–Induced Morbidity and Arthralgia
Jaspreet Jain MSc, Vimal Narayanan BSMS, MSc, Shivam Chaturvedi MVSc
et al.
Chikungunya viral fever results in extreme morbidity and arthralgia in affected individuals. Currently, modern medicines providing symptomatic relief for the acute febrile phase and the chronic arthritic phase are only options available. Traditional Indian medical system, however, uses specific formulations for treatment of this infection; one such polyherbal formulation used to treat the postpyretic phase of chikungunya is amukkara choornam . The current study was undertaken to study the efficacy of amukkara choornam in the treatment of chikungunya in C57BL/6J mice. The formulation when administered to chikungunya-infected mice relieved morbidity and joint swelling. Analysis of virus clearance in brain and joint tissues on formulation treatment revealed a direct correlation of viral load in brain to morbidity during infection; likewise, joint swelling receded prior to complete viral clearance explaining possible immunomodulatory effect of amukkara choornam. This study provides insight into the possible mode of action of amukkara choornam during chikungunya.
Other systems of medicine, Homeopathy