Hasil untuk "Otorhinolaryngology"

Paul Pickert, Anja Giers, Anke Lux et al.

<b>Background/Objectives</b>: Differentiating benign, premalignant, and early malignant vocal fold lesions is challenging. Perpendicular vascular changes (PVCs) per the European Laryngological Society (ELS) are key malignancy indicators. Enhanced contact endoscopy with narrow-band imaging (NBI-CE) visualizes intrapapillary capillary loops (IPCLs) at high magnification, independent of gross morphology. However, defining malignancy as any PVC increases sensitivity but lowers specificity—particularly in papillomas—whereas limiting malignancy to narrow-angle PVC improves specificity but risks false negatives and reduced reproducibility. <b>Methods</b>: We intraoperatively evaluated 146 histology-proven vocal fold lesions using NBI-CE. Six raters (three experienced otolaryngologists, three PhD students) classified vascular patterns. Two approaches were tested: (1) malignancy = narrow-angle PVC; (2) malignancy = any PVC. Outcomes were accuracy, sensitivity, specificity, and interrater agreement. <b>Results</b>: Approach (1) had higher specificity but lower sensitivity than (2) (~85% vs. ~70% specificity; ~50% vs. ~80% sensitivity). Accuracy did not differ significantly. Experienced raters showed higher interrater agreement and a more favorable sensitivity–specificity balance. Common errors were false positives in papillomas and false negatives in dysplasia/early carcinoma. <b>Conclusions</b>: PVC assessment with NBI-CE is feasible and informative. Choosing between “any PVC” and “narrow-angle only” entails a sensitivity–specificity trade-off and depends on lesion type and experience. Refined ELS descriptors and automated analysis may improve reproducibility and accuracy.

Núria Catasús, Gemma Casals-Sendra, Miguel Torres-Martin et al.

Amira Tarek Elgabarty, Ahmed Salah Elmahallawy, Ahmed Aly Ibraheam et al.

Abstract Background Oroantral fistula (OAF) involves pathological, epithelialized, and unnatural communication between the maxillary sinus and oral cavity. Recently, functional endoscopic sinus surgery has provided minimally invasive treatment options with fewer postoperative complications. The aim of the study was to evaluate the one-stage endoscopic middle meatal antrostomy (EMMA) technique with the application of a platelet-rich fibrin membrane (PRF) for OAF closure and maxillary sinusitis relief. Patients and methods Patients who suffered from OAF with odontogenic sinusitis were included in this study. Complete excision of the epithelial tract and any necrotic tissue was performed with proper curettage. Then, EMMA was performed with simultaneous closure of the OAF by the application of PRF membranes that were fixed by sutures and covered with an acrylic splint. Patients were clinically evaluated for OAF closure, pain level, and symptom relief. Additionally, the size of the bone defect was measured with the aid of computed tomography (CT) preoperatively and after 24 weeks postoperatively. Results This study included nine eligible patients with a mean age of 38 years. The data were collected, tabulated, and statistically analyzed. Soft tissue healing and bone formation occurred in all patients who achieved maxillary sinusitis relief without any complications. Additionally, pain was significantly lower on the 7th postoperative day than on the 1st postoperative day, according to the statistical analysis of the results (p < .001). Conclusions One-stage EMMA with the application of PRF membranes and acrylic splint represents a reliable alternative technique for OAF closure and maxillary sinusitis relief that is associated with a lower incidence of complications and minimal postoperative pain. Trial registration The trial was registered on 28/02/2024, at clinicaltrials.gov (ID: NCT06281873).

Jeon Gang Doo, Hye Kyu Min, Jin-Young Min

Background and Objectives Sinonasal fungal balls (FBs) most commonly occur in the maxillary sinus, followed by the sphenoid sinus (SS). Relatively little is known about the predisposing factors and pathogenesis of unilateral sphenoid sinus fungal balls (SSFBs) compared to maxillary sinus FBs. We investigated whether anatomical variations have clinical implications for the location of unilateral SSFBs. Methods This study included 33 patients who underwent endoscopic sinus surgery for unilateral SSFBs between 2010 and 2021. Preoperative computed tomography scans were used to analyze the presence of anatomical variations, including sphenoid lateral recess, complete accessory septum of the SS, types of SS pneumatization, anterior and posterior nasal septal deviation (NSD), cephalocaudal NSD, concha bullosa (CB), Haller cell (HC), paradoxical middle turbinate (MT), everted uncinated process (UP), and Onodi cell. Results The presence of HC (33.3% vs. 12.1%, p=0.04), complete accessory septum of the SS (51.6% vs. 25.8%, p=0.04), and the sellar type of the SS (90.9% vs. 50%, p=0.003) differed significantly according to the presence or absence of FBs in the SS. However, other anatomical variations, including NSD, CB, paradoxical MT, everted UP, Onodi cell, and sphenoid lateral recess, were not significantly associated with the presence of unilateral SSFBs (all p>0.05). In the multivariable analysis, only sellar-type pneumatization of the SS showed a statistically significant relationship with SSFB, not the combined conchal and presellar type (adjusted odds ratio, 8.96; 95% confidence interval, 1.27–63.19; p=0.03). Conclusion We demonstrated that unilateral SSFBs were most strongly associated with the ipsilateral type of SS pneumatization, followed by the presence of HC and a complete accessory septum of the SS. Intranasal anatomical variations may play a significant role in the location of unilateral SSFBs.

Hanan Anwar, Ahmed Ragab, Asmaa El-Dessouky Rashad

Abstract Background Since the declaration of COVID-19 as a pandemic in 2020, its main symptoms have primarily affected the respiratory system. However, it also presents other systemic manifestations, including symptoms related to the larynx and pharynx. COVID-19 has evolved into subsequent variants, starting from the alpha variant and currently dominated by the Omicron variant, with the Delta variant being the most severe. The study aimed to elucidate the laryngo pharyngeal manifestations related to Delta and Omicron variants of COVID-19 as well as the associated risk factors. Results This study adopted a case–control design. The data were collected from patients who attended the phoniatric outpatient clinic at Menoufia University Hospital from January to December 2022. Patients were categorized into three groups (50 patients each). Group I consisted of patients who exhibited COVID-19 Laryngo pharyngeal symptoms during the Delta wave (Group 1) and the Omicron wave (Group 2). The control group included non-COVID-19 participants. The symptoms related to the larynx and pharynx were documented. In addition, laryngoscopic and stroboscopic examinations were done. The age of individuals affected by the Delta variant was higher. Delta cases exhibited a higher rate of smoking, diabetes, hypertension, and COPD compared to Omicron cases. Additionally, Delta cases displayed greater severity. Dysphagia, dysphonia, choking attacks related to swallowing, and stridor had significant higher rate in the Delta variant compared to the Omicron variant. The Delta variant primarily exhibited unilateral vocal fold paralysis in 38% of cases, as well as bilateral vocal fold paresis and paralysis in 20% and 22% of cases, respectively. In contrast, Omicron cases predominantly showed vocal fold congestion (80% of cases). Delta cases were more prone to experiencing abnormalities in amplitude, symmetry, and periodicity. Conclusions The Delta variant is more prone to neurologic affection of the vocal folds manifesting as paresis and paralysis, whereas the Omicron variant, which has maintained its dominance thus far, experiences milder affection, primarily manifesting as congestion. Consequently, laryngeal affection with various degrees of severity is still suspected.

Gustavo Pedrosa Rocha, Patrícia Lopes, António Trigueiros et al.

Objectives: To determine and compare, retrospectively, the success rate of speech rehabilitation with voice prosthesis (VP) according to the age, radiotherapy (RT) status and total laryngectomy (TL) type: primary or salvage. Study design: By reviewing post-laryngectomy patients with voice prosthesis insertion between 2016-2022. Surgical and prosthesis complications, first prosthesis replacement and number of replacements per year were analysed. Material and Methods: Statistical analysis used t-student when there was normal distribution and Mann-Whitney when the group didn’t show normal distribution. P values <0.05 were considerer statistically significant. Results: In the groups age and type of TL, where was an absence of statistically significant difference in every variable. The post-RT group had, paradoxically, less prosthesis complications (p=0,036). Conclusion: Data had demonstrated that the benefits of a voice prosthesis protocol should not have age, salvage surgery and RT as restrictive factors.

Vural Akın, Mehmet Emre Sivrice, Veysel Atilla Ayyıldız et al.

Sialolithiasis is the primary cause of swelling in the major salivary glands. The etiopathogenesis is not clear. Adenoid cystic carcinoma is a slow-growing salivary gland malignancy with a poor prognosis. There are only a few cases in the literature reporting the coexistence of sialolithiasis and adenoid cystic carcinoma. In this report, we present a case that was thought to have sialolithiasis in the foreground because of the calcified image on computed tomography, but was diagnosed with adenoid cystic carcinoma after excision, together with a discussion of the relationship between sialolithiasis and carcinogenesis.

Arunabha Chakravarti, Prerna Negi, Parvendra Singh et al.

Abstract Background Sebaceous carcinoma is an uncommon non-melanoma skin cancer. Extraocular sites are extremely rare, with only a few cases reported in the medical literature. This article reviews the diagnostic challenges and treatment of a case of sebaceous carcinoma of nasal ala. Case presentation A 75-year-old female presented with a slow-growing right nasal alar mass for the last 1.5 years. It was nodular in appearance and covered with crusts and concretions. An incisional biopsy confirmed the diagnosis of sebaceous carcinoma. The patient underwent a wide local excision of the mass followed by nasolabial flap reconstruction. Conclusions Sebaceous Carcinoma should be included in the differential diagnosis of an elderly patient with nasal growth to avoid delaying treatment.

Tom Ebbers, Robert P Takes, Jimmie Honings et al.

Objective To describe the development and validation of automated electronic health record data reuse for a multidisciplinary quality dashboard. Materials and methods Comparative study analyzing a manually extracted and an automatically extracted dataset with 262 patients treated for HNC cancer in a tertiary oncology center in the Netherlands in 2020. The primary outcome measures were the percentage of agreement on data elements required for calculating quality indicators and the difference between indicators results calculated using manually collected and indicators that used automatically extracted data. Results The results of this study demonstrate high agreement between manual and automatically collected variables, reaching up to 99.0% agreement. However, some variables demonstrate lower levels of agreement, with one variable showing only a 20.0% agreement rate. The indicator results obtained through manual collection and automatic extraction show high agreement in most cases, with discrepancy rates ranging from 0.3% to 3.5%. One indicator is identified as a negative outlier, with a discrepancy rate of nearly 25%. Conclusions This study shows that it is possible to use routinely collected structured data to reliably measure the quality of care in real-time, which could render manual data collection for quality measurement obsolete. To achieve reliable data reuse, it is important that relevant data is recorded as structured data during the care process. Furthermore, the results also imply that data validation is conditional to development of a reliable dashboard.

Susanna Theophilus Yesupatham, SM Azeem Mohiyuddin, Sagayaraj Arokiyaswamy et al.

Introduction: There are increasing reports of the occurrence of fungal co-infections in Coronavirus disease-2019 (COVID-19) patients resulting in severe morbidity among predisposed individuals. Mucormycosis is an Invasive Fungal Infection (IFI). Early anticipation and identification of fungal co-infections can significantly reduce morbidity rate among COVID-19 infected patients. Aim: To determine quantitatively the levels of ferritin and D-dimer in COVID-19 infected patients with mucormycosis. Materials and Methods: This cross-sectional study was conducted on 84 Real Time Polymerase Chain Reaction (RT-PCR) positive for COVID-19 in oropharyngeal swab patients from June 2021 to August 2021 at Sri Devaraj Urs Medical College, Kolar, Karnataka, India. D-dimer and ferritin levels were measured in the patient’s blood sample using Latex Enhanced Immunoturbidimetric method in Vitros 5.1 FS and Vitros Eci Immunodiagnostics, respectively. Continuous data represented as mean and standard error of mean, Kruskal-Wallis test and Mann-Whitney U test was used to test significance, p-value <0.05 was considered as statistically significant. Results: Of the 84 COVID-19 Infected patients, 40 were included in group 1, 25 patients in group 2 and 19 patients in group 3. A total of 21 patients were aged between 20-40 years, 48 patients between 41-60 years age group and 15 patients were in 61-80 years of age group. The number of male patients was 63 and female patients were 21. The D-dimer levels were 1259.37±258.9, 2632.60±472.6 and 229.53±18.4 (p-value <0.001) in group 1, 2 and 3, respectively and ferritin levels were 528.58±45.03, 511.48±74.4, and 256.89±51.8 (p-value <0.007) in group 1, 2 and 3, respectively. Conclusion: Serum ferritin and plasma D-dimer were significantly elevated in COVID-19 patients with mucormycosis. Mucormycosis in COVID-19 patients without pre-existing co-morbidities may be attributed to the use of steroid therapy in these patients for COVID-19 infection. Thus, serum ferritin and plasma dimer levels may have a significant predictive role in the risk assessment for the development of mucormycosis among COVID-19 infected patients.

Natalie Layer, Anna Weglage, Verena Müller et al.

Hearing with a cochlear implant (CI) is limited compared to natural hearing. Although CI users may develop compensatory strategies, it is currently unknown whether these extend from auditory to visual functions, and whether compensatory strategies vary between different CI user groups. To better understand the experience-dependent contributions to multisensory plasticity in audiovisual speech perception, the current event-related potential (ERP) study presented syllables in auditory, visual, and audiovisual conditions to CI users with unilateral or bilateral hearing loss, as well as to normal-hearing (NH) controls. Behavioural results revealed shorter audiovisual response times compared to unisensory conditions for all groups. Multisensory integration was confirmed by electrical neuroimaging, including topographic and ERP source analysis, showing a visual modulation of the auditory-cortex response at N1 and P2 latency. However, CI users with bilateral hearing loss showed a distinct pattern of N1 topography, indicating a stronger visual impact on auditory speech processing compared to CI users with unilateral hearing loss and NH listeners. Furthermore, both CI user groups showed a delayed auditory-cortex activation and an additional recruitment of the visual cortex, and a better lip-reading ability compared to NH listeners. In sum, these results extend previous findings by showing distinct multisensory processes not only between NH listeners and CI users in general, but even between CI users with unilateral and bilateral hearing loss. However, the comparably enhanced lip-reading ability and visual-cortex activation in both CI user groups suggest that these visual improvements are evident regardless of the hearing status of the contralateral ear.

Kahori Hirose, Kento Asano, Masahiko Sakaguchi et al.

Abstract Objective Botulinum toxin (BT) therapy is a first‐line treatment for spasmodic dysphonia (SD). However, a detailed chronological course and clinical factors that affect the therapeutic effect have been vague. In this study, we analyzed the data from our placebo‐controlled, randomized, double‐blinded parallel‐group comparison/open‐label clinical trial of BT (Botox) to clarify these. Methods A total of 22 patients with abductor SD (ADSD) were enrolled. The female‐to‐male ratio was 20:2 with a mean age of 40.0 ± 10.3 years and a median duration of symptoms of 7.5 years. The therapeutic effect was evaluated based on the change in the number of aberrant morae (phonemes), GRBAS scale, Voice Handicap Index (VHI), and Visual Analogue Scale (VAS). Results The change in the number of aberrant morae peaked at 2 weeks and lasted for 12 weeks in the BT group with significance (P < .01) compared to the placebo group. Objective improvement (number of aberrant morae and [S] element in GRBAS) preceded subjective improvement (VHI and VAS). The change in number of aberrant morae and VHI showed a significant correlation (P < .01). The changes in the number of aberrant morae, VHI, and VAS in younger subjects were greater than in older subjects. Patients who presented with post‐treatment breathy hoarseness or dysphagia showed better therapeutic effects. Conclusions BT therapy was effective for ADSD based on both objective and subjective assessments. Improvements in subjective parameters were delayed compared to objective measures due to post‐treatment breathy hoarseness. However, this adverse event was believed to reflect the treatment effect. Level of Evidence 1b.

Joanna Katarzyna Strzelczyk, Krzysztof Biernacki, Jadwiga Gaździcka et al.

Human papillomavirus (HPV) is a virus with the potential to infect human epithelial cells and an etiological agent of many types of cancer, including head and neck cancer. The aim of the study was to determine the prevalence of HPV infection in patients with head and neck squamous cell carcinoma (HNSCC), patients with chronic tonsillitis, and healthy individuals, and to establish high- and low-risk HPV genotypes in these groups. The objectives also comprised the delineation of the relationship between the infection with high- or low-risk HPV subtypes and clinicopathological and demographic characteristics of the study groups. This study was composed of 76 patients diagnosed with HNSCC, 71 patients with chronic tonsillitis, and 168 cases without either of these conditions (the control group). HPV detection and identification of subtypes were performed on isolated DNA using a test which allowed detection of 33 common high-risk and low-risk HPV subtypes. The prevalence of HPV infection was 42.1%, 25.4%, and 37.5% in HNSCC, chronic tonsillitis, and control groups, respectively. HPV 16 was the most prevalent genotype in all groups and the non-oncogenic HPV 43/44 was frequent in HNSCC patients. This analysis provides insight into the prevalence of oral oncogenic and non-oncogenic HPVs in patients with head and neck cancer, patients with chronic tonsillitis and healthy individuals, and leads to the conclusion that further investigations are warranted to examine a larger cohort of patients focusing on high- and low-risk HPV genotypes. Efforts should be focused on screening and prevention strategies, and therefore, it is important to introduce tools for effective detection of HPV genotypes. Furthermore, given the role of vaccines against oral HPV infection, our observations lead to the suggestion that HPV vaccination should be of considerable importance in public health strategies.

M. Cesárea Sánchez-Hernández, Ana M. Navarro, Carlos Colás et al.

Abstract Background Allergic conjunctivitis (AC) is usually associated to allergic rhinitis (AR), but the severity and control of ocular symptoms should be assessed independently to improve diagnosis and treatment. The criteria from the Spanish consensus document on allergic conjunctivitis (DECA) aimed to be used as a patient-reported instrument for AC management. Here we validate these criteria for classifying AC severity and defining its control following COSMIN guidelines recommendations. Methods Patients with moderate or severe AR [reflective total nasal symptom score (rTNSS) score ≥ 8] and concomitant AC were recruited from hospitals in Spain. Patients were classified according to the severity of ocular symptoms as mild, moderate, or severe, and classified with respect to control as controlled and non-controlled, using the DECA criteria. To validate these criteria, comparisons with the validated modified allergic rhinitis and its impact on asthma (mARIA), reflective total ocular symptom score (rTOSS), rhinitis control assessment test (RCAT), ESPRINT-15 questionnaires, a conjunctival hyperemia scale and a visual analogue scale (VAS) for ocular symptoms were performed. Results A total of 128 patients participated in the validation. Mean age was 34.4 ± 12.1 years; 72.7% were women. The DECA criteria showed a good discriminant validity, reflecting a high capacity to differentiate between mild, moderate, and severe patients, and controlled from uncontrolled patients. A strong association between AC and AR was reflected in the comparison between the DECA and the mARIA criteria (p < 0.0001). The DECA criteria for severity and control presented satisfactory properties for longitudinal validity and responsiveness. Conclusions Validation of the DECA criteria for severity and control of AC suggested that it can be useful in the evaluation of eye symptoms and follow-up of therapies.

Seok Won Jeon, Chang Hoi Kim, Joo Yeon Kim et al.

A 54-year-old man, suffering from severe headache and ophthalmoplegia after undergoing endoscopic sinus surgery was referred to a tertiary hospital. Computed tomography (CT) revealed soft tissue density lesions in the left sphenoid sinus. The internal carotid artery was shown to be occluded in brain magnetic resonance imaging (MRI) scans without any other cerebral lesion. Endoscopic view of left nasal cavity shows whitish hyphae in the ethmoid and the sphenoid sinuses. We diagnosed him with cavernous sinus syndrome caused by mucormycosis and conducted endoscopic sinus surgery to remove remaining lesions and decompress orbit and optic nerves. After the revision surgery the patient's headache and ophthalmoplegia were improved. However, multifocal cerebral infarctions were newly discovered in a postoperative CT scan. We experienced a case of mucormycosis of sphenoid sinus resulting in occlusion of internal carotid artery and multifocal cerebral infarction, and report it with a brief review of these disease entities.

Waynn-Nielsen C. Destriza, Roderick B. De Castro, Howard M. Enriquez

Objective: The study aims to compare the maximum sound output capabilities of different earphone types/music style combinations. The study also intends to assess the preferred listening levels (PLL) of test subjects using different earphone types with background noise accession. The study also seeks to determine the presence or absence of a threshold shift on headphone/music style combination PLL’s that exceed the recommended noise limit. Methods Study Design:            Experimental Study Setting:                       Tertiary Government Hospital Subjects: Thirty (30) hearing healthy volunteers were sampled from hospital staff aged 18-40 years, with no known history of ear pathology and/or use of any known ototoxic drugs, with normal otoscopy and audiograms of less than 20dB from 125Hz to 8000Hz, and no exposure to loud noise from any source within the previous 3 days. The sound pressure levels (SPL) delivered by three (3) types of earphones (earbud type, in-ear type, supra-aural type) were measured at maximum volume setting of a personal media player (iPod, Apple Inc.), while playing different music genres. The test subjects were asked to listen at their preferred listening levels (PLL) using the different types of earphones at increasing background noise accession. Results: The earbud type averaged the greatest SPL among the earphone types, and pop music averaged the greatest SPL among the music styles. Comparison of the maximum output capabilities revealed that there was a significant difference among different brands of earphones of the same type. However, no significant difference were found among songs of similar music style and across different music styles in all earphones except the in-ear type. PLL average was at 90.4dB in a silent environment with increasing intensity as background noise accentuated. Supra-aural earphones registered the least increase in PLL in a loud environment, due to its higher background noise-attenuating capabilities. Conclusion: Having a significant difference among earphone types with regard their maximum output capabilities, it is recommended to check the specifications of the earphone type one intends to use. In using personal media players (PMP), the volume should be set at the lowest comfortable level. While choice of music style remains the discretion of the listener, the choice of music style should be considered for long periods of listening. Because the PLL of test subjects were alarmingly high, the authors recommend intervention in their listening habits. Background noise attenuating capabilities of earphones play a factor in reducing excessive sound energy from reaching the ear, reducing the PLL, and decreasing the risk for noise-induced hearing loss. Keywords:     earphones, music styles, personal media players, preferred listening levels, recreational noise, noise-induced hearing loss

N. Hakuba, N. Hato, Yoshinori Omotehara et al.

Dear Editor, Tympanic membrane perforation is frequently encountered in outpatient otorhinolaryngology practice. We have introduced a treatment procedure to promote regeneration of the tympanic membrane and closure of perforations using an atelocollagen sponge/silicone membrane combined with human basic fibroblast growth factor that promotes wound healing.1,2 This report describes epithelial pearl formation following our outpatient-based tympanic membrane regeneration therapy.

Shraddha Jain, Ansu Sam, Dennis I. Yohannan et al.

Department of Otorhinolaryngology and Head and Neck Surgery, Jawahar Lal Nehru Medical College, DMIMS(DU), Sawangi, Wardha 442005, Maharashtra, India Department of Radiology, Jawahar Lal Nehru Medical College, DMIMS(DU), Sawangi, Wardha, Maharashtra, India Department of Medicine, Jawahar Lal Nehru Medical College, DMIMS(DU), Sawangi, Wardha, Maharashtra, India Department of Pathology, MGIMS, Sewagram, Wardha, Maharashtra, India Department of Neurosurgery, MGIMS, Sewagram, Wardha, Maharashtra, India

Giseli Rebechi, Thiago Pontes, E. Braga et al.

Abstract Introduction In most ear, nose, and throat services, it is routine to send the material extracted from tonsillectomy for histologic study to research malignancy, to analyze suspect material, or to provide medical-legal documentation. Recent studies have shown that this routine analysis is dispensable. Objective To evaluate the actual need and perform a cost–benefit analysis of routine histopathologic examination in tonsillectomy with no signs or symptoms of malignancy. Methods A retrospective observational study evaluated the charts of patients undergoing adenotonsillectomy, tonsillectomy, or adenoidectomy from January 2008 to September 2009 at the Institute of Otorhinolaryngology CEMA-SP. Costs of this test for the public health system were analyzed and the literature reviewed. Results We studied 281 patients between 2 and 22 years of age; 142 (50.5%) were male and 139 (49.5%) were female. Of the surgeries, 201 were adenotonsillectomies (71.5%), 41 were tonsillectomies (14.5%), and 39 were adenoidectomies (14%). The most common indication for surgery was recurrent infection (63.3%). None of study patients had clinical suspicion of malignancy. The tests showed a cost of R$20.03 per tonsil analyzed. Conclusion Routine histopathologic examination in patients undergoing adenotonsillectomy with no signs or symptoms of malignancy is dispensable and increases the cost of the surgeries.

Danielle Carneiro, Luciana Rodrigues Belo, Maria das Graças Wanderley de Sales Coriolano et al.

A doença de Parkinson pode causar distúrbios da deglutição em qualquer fase da doença devido às disfunções dos movimentos. Apesar da diversidade de sintomas, normalmente as alterações iniciais na deglutição do parkinsoniano são despercebidas e podem ocasionar prejuízo na qualidade de vida. Contudo, instrumentos que avaliam a qualidade de vida em disfagia na doença de Parkinson não têm sido sistematicamente estudados. Esta revisão sistemática objetivou identificar a utilização do questionário de Qualidade de Vida em Disfagia para avaliação na doença de Parkinson. Foram incluídos artigos com sujeitos de ambos os sexos e com doença de Parkinson idiopática, e excluídos os artigos de avaliação de tratamento e que apresentaram indivíduos com outra forma de parkinsonismo. Após a busca realizada nos portais da Bireme, Pubmed e Banco de Teses da Capes, foram analisados 30 artigos, dos quais dois foram incluídos depois da aplicação da Escala de Jadad modificada. Os dois artigos evidenciaram que o questionário de Qualidade de Vida em Disfagia é um instrumento seguro e relevante para avaliar alterações da deglutição do parkinsoniano nos domínios do instrumento, exceto no sono. Além disso, o questionário pode indicar uma compreensão da qualidade de vida geral. Sendo assim, a utilização do questionário de Qualidade de Vida em Disfagia contribuiu para avaliação da qualidade de vida em disfagia de sujeitos com doença de Parkinson.