Hasil untuk "History"

Araj Sekh

Women’s rights in Islam are often debated and frequently misunderstood due to cultural practices and selective interpretations. This paper examines the historical evolution of women’s rights in Islam from pre-Islamic Arabia to modern times. It aims to show how Islamic teachings brought significant reforms in the social, legal, and moral status of women. Before Islam, women faced severe discrimination, denial of inheritance, and lack of personal choice. Islam addressed these injustices by granting women rights to inheritance, consent in marriage, education, religious responsibility, and participation in social life. The study also highlights the important contributions of Muslim women scholars, jurists, and educators during the prophetic and medieval periods. In addition, the paper briefly discusses Muslim feminism and contrasts it with Western feminist thought to clarify key ideological differences. Based on Qur’anic teachings, Hadith, and historical evidence, the paper argues that Islam fundamentally supports dignity, justice, and equity for women. The study concludes that many contemporary challenges faced by Muslim women arise from cultural misuse of religion rather than Islamic principles themselves. Understanding Islam through authentic sources is essential for an accurate view of women’s rights.

Franjo Matanović

Proza.

Alex Alarcon, Andrew P. Hearin, Matthew R. Becker et al.

We present DiffstarPop, a differentiable forward model of cosmological populations of galaxy star formation histories (SFH). In the model, individual galaxy SFH is parametrized by Diffstar, which has parameters $θ_{\rm SFH}$ that have a direct interpretation in terms of galaxy formation physics, such as star formation efficiency and quenching. DiffstarPop is a model for the statistical connection between $θ_{\rm SFH}$ and the mass assembly history (MAH) of dark matter halos. We have formulated DiffstarPop to have the minimal flexibility needed to accurately reproduce the statistical distributions of galaxy SFH predicted by a diverse range of simulations, including the IllustrisTNG hydrodynamical simulation, the Galacticus semi-analytic model, and the UniverseMachine semi-empirical model. Our publicly available code written in JAX includes Monte Carlo generators that supply statistical samples of galaxy assembly histories that mimic the populations seen in each simulation, and can generate SFHs for $10^6$ galaxies in 1.1 CPU-seconds, or 0.03 GPU-seconds. We conclude the paper with a discussion of applications of DiffstarPop, which we are using to generate catalogs of synthetic galaxies populating the merger trees in cosmological N-body simulations.

Qiaorong S. Yu, Stephanie O'Neil, Xuejian Shen et al.

In this study, we define the novel splashback depth $\mathcal{D}$ and width $\mathcal{W}$ to examine how the splashback features of dark matter haloes are affected by the physical properties of haloes themselves. We use the largest simulation run in the hydrodynamic MillenniumTNG project. By stacking haloes in bins of halo mass, redshift, mass-dependent properties such as peak height and concentration, and halo formation history, we measure the shape of the logarithmic slope of the density profile of dark matter haloes. Our results show that the splashback depth has a strong dependence on the halo mass which follows a power law $\mathcal{D}\propto\left(\log_{10}M\right)^{2.8}$. Properties with strong correlation with halo mass demonstrate similar dependence. The splashback width has the strongest dependence on halo peak height and follows a power law $\mathcal{W}\proptoν^{-0.87}$. We provide the fitting functions of the splashback depth and width in terms of halo mass, redshift, peak height, concentrations and halo formation time. The depth and width are therefore considered to be a long term memory tracker of haloes since they depend more on accumulative physical properties, e.g., halo mass, peak height and halo formation time. They are shaped primarily by the halo's assembly history, which exerts a stronger influence on the inner density profile than short-term dynamical processes. In contrast, the splashback features have little dependence on the short term factors such as halo mass accretion rate and most recent major merger time. The splashback depth and width can therefore be used to complement information gained from quantities like the point of steepest slope or truncation radius to characterise the halo's history and inner structure.

Qishuai Zhong, Zongmin Li, Siqi Fan et al.

Effective engagement by large language models (LLMs) requires adapting responses to users' sociodemographic characteristics, such as age, occupation, and education level. While many real-world applications leverage dialogue history for contextualization, existing evaluations of LLMs' behavioral adaptation often focus on single-turn prompts. In this paper, we propose a framework to evaluate LLM adaptation when attributes are introduced either (1) explicitly via user profiles in the prompt or (2) implicitly through multi-turn dialogue history. We assess the consistency of model behavior across these modalities. Using a multi-agent pipeline, we construct a synthetic dataset pairing dialogue histories with distinct user profiles and employ questions from the Value Survey Module (VSM 2013) (Hofstede and Hofstede, 2016) to probe value expression. Our findings indicate that most models adjust their expressed values in response to demographic changes, particularly in age and education level, but consistency varies. Models with stronger reasoning capabilities demonstrate greater alignment, indicating the importance of reasoning in robust sociodemographic adaptation.

J. Menken

Louisa Ashby, Lydia Chan, Christine Winterbourn et al.

Abstract Objectives Dominant‐activating (DA) lesions in RAC2 have been reported in 18 individuals to date. Some have required haematopoietic stem cell transplantation (HSCT) for their (severe) combined immunodeficiency syndrome phenotype. We aimed to investigate clinical and cellular features of a kindred harbouring a novel variant in RAC2 p.Ile21Ser (I21S) to better understand DA lesions' phenotypic spectrum. Methods Clinical and immunological information was collated for seven living individuals from the same kindred with RAC2 p.I21S. We evaluated neutrophil morphology, RAC2 protein expression and superoxide production using freshly isolated neutrophils stimulated with phorbol‐12‐myristate‐13‐acetate (PMA) and N‐formyl‐MetLeuPhe (fMLP). Results Patient 1 (P1, aged 11, male) has a history of bacterial suppurative otitis media, viral and bacterial cutaneous infections. P1's siblings (P2, P3), mother (P4), maternal aunt (P5) and uncle (P6) have similar infection histories. P1's maternal cousin (P7) presented with Burkitt's lymphoma at age 9. All affected individuals are alive and none has required HSCT to date. They have chronic lymphopenia affecting the CD4+T and B‐cell compartments. P1–3 have isolated reduction in IgM levels whereas the adults universally have normal immunoglobulins. Specific antibody responses are preserved. Affected individuals have neutrophil vacuolation, and their neutrophils have enhanced superoxide production compared to healthy controls. Conclusion RAC2 p.I21S is an activating variant causing notable morphological and functional abnormalities similar to other reported DA mutations. This novel variant expands the broad clinical phenotypic spectrum of RAC2 DA lesions, emphasising the need to tailor clinical management according to patients' disease phenotype and severity.

Manuela Davanzo, Giosuè Cuccurullo, Elena Zwirner et al.

We report the first observation of the psammophyte plant species Pancratium maritimum L. (Amaryllidaceae) in the Friuli Venezia Giulia region, Italy. Four adult individuals were observed in spring 2023 on the residual dunes of Lignano Sabbiadoro municipality behind a beach resort. Although we lack genetic analysis to determine its provenance, considering the absence of locally cultivated individuals and the expansion of the species in the neighboring region of Veneto, with individuals located ca. 20 km from this reported observation, we believe that its arrival in Friuli Venezia Giulia should be considered a spontaneous spread of a new native species for the region. This finding indicates that the species now has a distribution extending along the entire Italian coastline.

Meri Pihanperä, Jaana Lepistö, Jarmo Kinos et al.

Tässä artikkelissa tarkastellaan suomalaiseen varhaiskasvatuksen opettajankoulutukseen sisältyvien opetusharjoitteluiden järjestämisen kehittymistä vuosina 1863–2020 mallikoulujen seimistä ja lastentarhoista yliopistolliseen harjoittelupäiväkoti Rauman pikkunorssiin. Tutkimustehtäviä on kaksi, joista ensimmäisen tavoitteena on selvittää, millaiseen historialliseen taustaan yliopistollinen harjoittelupäiväkotikonsepti rakentuu, ja toisen tavoitteena on tutkia, millaiseksi konseptiksi se kehittyi. Tutkimusaineistoina käytettiin opetusharjoittelujärjestelmän kehittymisen vaiheita ja keskeisiä tapahtumia käsitteleviä historian tutkimuksia, viranomaisten selvityksiä, hallinnollisia ja lainsäädännöllisiä asiakirjoja sekä Rauman pikkunorssin suunnittelusta vastanneiden asiantuntijaryhmien kokousmuistioita (N=21) vuosien 2017–2020 aikana. Aineistot analysoitiin aineistolähtöisellä sisällönanalyysilla. Tutkimuksen tuloksena tarkastellaan varhaiskasvatuksen opettajankoulutuksen ja luokanopettajankoulutuksen eroavuutta niiden opetusharjoitteluiden kehittymisen osalta sekä kuvataan Rauman pikkunorssia yhtenä ratkaisuyrityksenä opettajankoulutuksen opetusharjoittelujärjestelmän yhtenäistämiseksi Turun yliopistossa. Lisäksi esitellään Rauman pikkunorssin kehittymistä tilojen, toimintojen ja toimijoiden kautta määriteltynä. Yhteenvetona tarkastellaan varhaiskasvatuksen opettajankoulutuksen opetusharjoittelujärjestelmän kehittymisen käännekohtia ja yliopistollisen harjoittelupäiväkodin perustamista osana sitä.

Nanzhe Wang, Louis J. Durlofsky

Geological carbon storage entails the injection of megatonnes of supercritical CO2 into subsurface formations. The properties of these formations are usually highly uncertain, which makes design and optimization of large-scale storage operations challenging. In this paper we introduce a history matching strategy that enables the calibration of formation properties based on early-time observations. Early-time assessments are essential to assure the operation is performing as planned. Our framework involves two fit-for-purpose deep learning surrogate models that provide predictions for in-situ monitoring well data and interpreted time-lapse (4D) seismic saturation data. These two types of data are at very different scales of resolution, so it is appropriate to construct separate, specialized deep learning networks for their prediction. This approach results in a workflow that is more straightforward to design and more efficient to train than a single surrogate that provides global high-fidelity predictions. The deep learning models are integrated into a hierarchical Markov chain Monte Carlo (MCMC) history matching procedure. History matching is performed on a synthetic case with and without 4D seismic data, which allows us to quantify the impact of 4D seismic on uncertainty reduction. The use of both data types is shown to provide substantial uncertainty reduction in key geomodel parameters and to enable accurate predictions of CO2 plume dynamics. The overall history matching framework developed in this study represents an efficient way to integrate multiple data types and to assess the impact of each on uncertainty reduction and performance predictions.

Michele Moresco

As revealed by Hubble in 1928, our Universe is expanding. This discovery was fundamental to widening our horizons and our conception of space, and since then determining the rate at which our Universe is expanding has become one of the crucial measurements in cosmology. At the beginning of this century, these measurements revealed the unexpected behavior that this expansion is accelerating and allowed us to have a first glimpse of the dark components that constitute $\sim$95\% of our Universe. Cosmic chronometers represent a novel technique to obtain a cosmology-independent determination of the expansion of the Universe, based on the differential age dating of a population of very massive and passively evolving galaxies. Currently, with this new cosmological probe it is possible to constrain the Hubble parameter with an accuracy of around 5\% at $z\sim0.5$ up to 10-20\% at $z\sim2$. In this Chapter, the cosmic chronometers approach is presented, describing the method and how an optimal sample can be selected; it is then discussed how the most recent measurements of the expansion history of the Universe have been obtained with this approach, as well as the cosmological constraints that can be derived. Particular attention will be given to the systematics involved in this approach and the treatment to properly take them into account. We conclude by presenting forecasts that show how future spectroscopic surveys will significantly boost the accuracy of this method and open the possibility to a percent determination of the Hubble constant, making cosmic chronometers a powerful independent tool to derive information on the expansion history of the Universe.

E. Farber, L. Nall

H. R. Jauss, E. Benzinger

Hana Anindya Indana, Ira Puspitawati, Dyah Samti Mayasari et al.

Objectives. This research aims to investigate whether there is an association between acute hyperglycemia and diabetes mellitus and the amount of circulating platelet-derived microparticles (PDMPs) during acute myocardial infarction (AMI) initial episode. Methodology. This was a cross-sectional study. Subjects were AMI patients underwent hospitalization. Demography and clinical data were obtained from hospital records. Diabetes mellitus was defined from history of disease, antidiabetic use and/or level of HbA1C ≥6.5%. Levels of HbA1c, admission random and fasting blood glucose levels were measured in hospital laboratory. The PDMPs was measured by flow-cytometry method, by tagging with CD-41 FITC and CD-62 PE markers and threshold size of <1 µm, from venous blood. The circulating PDMPs amount was compared according to glucometabolic state, namely acute hyperglycemia (admission random glucose ≥200 mg/dL and fasting glucose ≥140 mg/dL) and diabetes mellitus. The comparative analysis between group was conducted with Student T tests or Mann-Whitney tests, where applicable. Results. A total of 108 subjects were included and their data analyzed. Circulating PDMPs amount was significantly lower in subjects with admission random glucose  ≥200 mg/dL as compared to those with below level (median (interquartile range (IQR)): 2,710.0 (718.0-8,167.0) count/mL vs. 4,452.0 (2,128.5-14,499.8) count/mL, p=0.05) and in subjects with fasting glucose  ≥140 mg/dL as compared to those with below level (median (IQR): 2,382.0 (779.0-6,619.0) count/mL vs. 5,972.0 (2,345.7-14,781.3) count/mL, p=0.006). Circulating PDMPs amount was also significantly lower in diabetes mellitus as compared to non diabetic  (median (IQR): 2,655.0 (840.0-5,821.0) count/mL vs. 4,562.0 (2,128.5-15,055.8) count/mL; p=0.007). Conclusion. Acute hyperglycemia and diabetes mellitus significantly associated with lower amount of circulating PDMPs during the initial episode of AMI.

P. K. Hitti

Elin Axén, Johan Stranne, Marianne Månsson et al.

Abstract Objective We evaluated long-term risk for biochemical recurrence and subsequent prognosis in a population-based cohort. Material and Methods We used register-based data to evaluate 6 675 consecutive patients having radical prostatectomy in Västra Götaland county in Sweden during 1995–2014. Patients were followed until death or end of study, 31 December 2014. Data were collected from registers on national, regional and local level and linked by means of the Swedish personal identity number. Biochemical recurrence was defined as PSA ≥0.2 ng/ml; failure as hormonal treatment, metastasis or prostate cancer death. Survival analysis was used to estimate time to biochemical recurrence and time to failure after biochemical recurrence for patients with 0 − 2 years, 2–5 years, 5–10 years and >10 years interval to biochemical recurrence, respectively. Results A total of 1214 men had biochemical recurrence during follow-up. Biochemical recurrence-free survival was 83% (95% confidence interval [CI] 82–84%), 75% (95% CI 74–77%) and 69% (95% CI 67–71%) at 5, 10 and 15 years, respectively. Cumulative incidence of failure for all patients 15 years after biochemical recurrence was 50% (95% CI 43–55%) in competing risk analysis. The risk of failure after biochemical recurrence was highest among patients having biochemical recurrence within 2 years from surgery. Incomplete data on PSA-history is a limitation. Conclusions The risk for biochemical recurrence persists 15 years after surgery. Follow-up should continue as long as treatment would be considered in case of recurrent disease.

Fuli Zhou, Yandong He, Felix T. S. Chan et al.

With the increasing demand of individual customption and awareness of cost reduction in express delivery organizations, the Chinese express industry faced with serious challenges especially under the background of government’s strict restrictions on environment and transportation. Therefore, a new service mode called joint distruction (JD) is being tried by the logistics industry, which is expected to address the challenges on online shopping. However, the insufficient understanding of JD adoption factors and their complicated interactions blocks the effectively implementation of the joint distribution. This study aims at identifying potential factors for JD adoption and promoting an effective joint distribution by discovering the interactive relationships among addressed factors. Firstly, potential ingredients for the adoption and implementation of JD are summarized from the literature and industrial interviews. Then, 23 variables are selected and classified into as objectives, drivers, barriers and affected operations. The Interpretive Structural Modeling (ISM) approach is then employed to analyze the crucial factors and the mutual influences amongst 23 variables. Finally, a case study is performed to construct the hierarchical structure of factors toward joint distribution adoption using the proposed ISM-modeling steps. The perplex hierarchical co-relationships are also identified by categorizing the driving variables and dependent variables. Results can assist express enterprises to promote the novel joint distribution mode and acheive higher efficiency of logistics operation by better understanding on crucial factors of JD adoption and implementation.

Justin M. Campbell, Jim Ballard, Kevin Duff et al.

Introduction: Essential tremor (ET) was long considered a monosymptomatic disorder, but this view has given way to a more comprehensive clinical picture that involves consideration of non-tremor symptoms (e.g., balance impairment, cognitive impairment). Recently, the novel designation of “ET-plus” was proposed to reclassify ET patients who demonstrate these non-tremor clinical features, but the prevalence of ET-plus remains poorly defined. The primary aim of our study was to estimate the prevalence of ET-plus among presurgical patients with ET by applying this reclassification scheme. Methods: We performed a retrospective review of patients with ET being considered for deep brain stimulation or focused ultrasound thalamotomy. Patient demographics and data from their clinical workups were collected. As part of their clinical workup, patients were screened for preexisting balance and cognitive impairment. Patients with ET were designated as ET-plus if they had balance impairment, cognitive impairment, or tremor at rest. We performed a series of Pearson correlations to examine how individual clinical and demographic variables were related. Results: We identified 92 patients who met the study criteria. Our results indicate that 87% of the presurgical patients in our cohort met the criteria for reclassification as ET-plus. In addition, we observed robust correlations between patient age and balance impairment, cognitive impairment, history of falls, family history of tremor, and ET-plus reclassification. Conclusion: We propose that balance and gait impairment should be assessed preoperatively alongside neuropsychological evaluation to improve the counseling and treatment of patients with ET-plus.

Jiamin Yu

With the popularity of Telematics and Self-driving, more and more rating factors, such as mileage, route, driving behavior, etc., are introduced into actuarial models. There are quite a few doubts and disputes on the rationality and accuracy of the selection of rating variables, but it does not involve the widely accepted historical claim records. Recently, Tesla Insurance released a new generation of Safety Score-based insurance, irrespective of accident history. Forward-looking experts and scholars began to discuss whether claim history will disappear in the future auto insurance rate-making system. Therefore, this paper proposes a new risk variable elimination method as well as a real-time road risk model design framework and concludes that claim history will be regarded as a "noise" factor and deprecated in the Pay-How-You-Drive model.

C. Mcevedy, Richard d. Jones