Vivek Kumar, Mahendra Yadav, Kunal Dhankhar
et al.
The physicochemical properties of insoluble Prussian blue (PB) play an important role in its thallium binding ability. Therefore, the present study aimed to characterise various physicochemical parameters of PB available commercially and compare them with the USFDA-approved Radiogardase ® -Cs. In addition, PB was synthesised by indirect and direct methods. PB samples and Radiogardase®-Cs were analysed for various parameters like particle size, moisture content, and thermogravimetric analysis (TGA) and correlated with its Maximum Binding Capacity (MBC) for thallium. Radiogardase ® -Cs showed the highest MBC of 238 mg/g for thallium with D 90 of 785 μm and moisture content of 23.24 %. The MBC of other PB samples was found to be significantly lower than Radiogardase ® -Cs which was found to be directly proportional to the moisture content. However, other parameters like particle size, and iron content vary significantly but no correlation was observed with MBC for thallium. This finding suggests that moisture content and MBC are extremely important parameters for optimising the PB to achieve desirable pharmacological efficacy for removing thallium in vivo.
AbstractPurpose To evaluate prognostic factors in newly diagnosed nvAMD.Methods Forty eyes of 37 patients with nvAMD received 0.5mg of intravitreal ranibizumab (IVR) monthly. One month after the third IVR, responders were defined as patients having improved visual acuity without retinal fluid.Results 22 eyes (55%) were responders. Multivariate logistic regression identified thicker subfoveal choroidal thickness (SFCT) (p=0.049) and smaller choroidal neovascularization (p=0.043) as predictive factor for responder. SFCT were significantly thicker in responders (257 vs. 167 μm) even after adjusting for age and spherical equivalent. (p=0.024)Conclusion Thinner choroidal thickness is negative prognostic factor for response to IVR in nvAMD.
Constantin Hoch, Johannes Bender, Andreas Wohlfarth
et al.
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
PENENTUAN KETIDAKPASTlAN ANALlSIS Ti, V, Cl, Ce, Cr, Cs, Sc, Co, Fe, dan Ca DALAM SAMPEL PADAT SECARA AANI MENGGUNAKAN STANDAR ADISI SESUAl SNI-I7025. Telah ditentukan ketidakpastian dalam analisis unsur-unsur Ti, V, Cl, Ce, Cr, Cs, Sc, Co, Fe, dan Ca, dalam sampel padat secara AANI (Analisis Aktivasi Neutron Instrumental) dengan metode komparatif dan standar adisi di P3TM BATAN. Sebagai contoh telah disajikan perhitunlgan ketidakpastian analisis unsur Ti. Ketidakpastian dalam INAA berasal dari cara sampling, preparasi sample, preparasi standar, irradiasi dan pencacahan. Sampel dalam percobaan ini diperoleh dari IAEA sudah siap analisis sehingga hanya faktor-faktor, preparasi sampel, preparasi standar, irradiasi dan pencacahan yang dipertimbangkan. Analisis dilakukan secara relatif, sampel maupun standar diirradiasi bersama-sama dalam satu kelongsong agar ketidakpastian dari faktor-faktor irradiasi (meliputi lama irradiasi, fluks neutron, geometri irradiasi), dan sifat-sifat isotopik dapat tereliminasi. Ketidakpastian yang diperoleh dari faktor pencacahan meliputi ketidakpastian dari peluruhan nuklida selama periode pencacahan, hilangnya pulsa karena penjumlahan random, geometri pencacahan. dan laju cacah. Cara relatif ini juga menyebabkan perbedaan waktu pencacahan (diatur dengan alat yang sama), perbedaan geometri pencacahan, ketebalan sampel, fluks neutron, waktu irradiasi dapat teriliminasi. Hasil fisi tidak ada karena tidak terdeteksi adanya uranium dalam sampel yang dianalisis. Tidak adanya perubahan jumlah nuklida target karena selama irradiasi tidak terjadi pembakaran, dan perubahan status kimia tidak mempengaruhi hasil analisis.
Institute for Philosophy, Political Science and Religion Studies CS MES RK, Kazakhstan, Sh.M. Zhandossova, М.М. Nurov
et al.
This article comprehensively examines the historical and political retrospective of the concepts of religious extremism and terrorism. The authors studied in detail the essence of the terms "extremism" and "terrorism", analyzed their ideological concepts. In the article, the authors considered the concepts of religious extremism and terrorism, and also used the methods and techniques of structural-functional, historical and comparative methodology to reveal their essence. This article was prepared in the framework of the research project BR05236488 "Formation of Kazakhstan's Identity in the Context of Modernization of Public Consciousness".