Hasil untuk "Dentistry"

G. Orphanides, D. Reinberg

Jan Derks, D. Schaller, Jan Håkansson et al.

M. Cadenaro, U. Josic, T. Maravic et al.

There have been significant advances in adhesive dentistry in recent decades, with efforts being made to improve the mechanical and bonding properties of resin-based dental adhesive materials. Various attempts have been made to achieve versatility, introducing functional monomers and silanes into the materials’ composition to enable the chemical reaction with tooth structure and restorative materials and a multimode use. The novel adhesive materials also tend to be simpler in terms of clinical use, requiring reduced number of steps, making them less technique sensitive. However, these materials must also be reliable and have a long-lasting bond with different substrates. In order to fulfill these arduous tasks, different chemical constituents and different techniques are continuously being developed and introduced into dental adhesive materials. This critical review aims to discuss the concepts behind novel monomers, bioactive molecules, and alternative techniques recently implemented in adhesive dentistry. Incorporating monomers that are more resistant to hydrolytic degradation and functional monomers that enhance the micromechanical retention and improve chemical interactions between adhesive resin materials and various substrates improved the performance of adhesive materials. The current trend is to blend bioactive molecules into adhesive materials to enhance the mechanical properties and prevent endogenous enzymatic degradation of the dental substrate, thus ensuring the longevity of resin–dentin bonds. Moreover, alternative etching materials and techniques have been developed to address the drawbacks of phosphoric acid dentin etching. Altogether, we are witnessing a dynamic era in adhesive dentistry, with advancements aiming to bring us closer to simple and reliable bonding. However, simplification and novelty should not be achieved at the expense of material properties.

LI Chenxi, GONG Zhongcheng, ZHAO Huarong, LIU Ying

The treatment of head and neck cancer is dominated by surgery and radiochemotherapy. For elderly patients, however, the rationality of invasive treatment is questioned in clinical practice. Although the proportion of geriatric patients with head and neck cancer is increasing, there are few consistent standards in the literature and guidelines. From the perspective of evidence-based medicine, this paper presents current evidence for treatment so as to provide specific recommendations for treating head and neck cancer in the elderly. Furthermore, based on a systematic literature review, a clinical algorithm is proposed to evaluate the treatment risk of elderly patients with head and neck cancer.

Steven Chiliquinga Velez, Thainah Bruna Santos Zambrano, Marcos Antonio Mendieta Cedeño

La salud bucodental es esencial para el bienestar general y el rendimiento deportivo, pero a menudo es descuidada por los atletas. Esta revisión tiene como objetivo identificar la relación entre el estado de salud bucodental y el rendimiento deportivo de los atletas. Se realizó una búsqueda exhaustiva de literatura publicada entre 2019 y 2023 en bases de datos como Scopus, PubMed, Web of Science y SciELO, utilizando descriptores clave relacionados con el rendimiento atlético y la salud bucal. Los resultados revelan que los traumatismos bucodentales más frecuentes en deportistas incluyen fracturas dentales, luxaciones, avulsiones y lesiones de encía, mucosa y hueso de soporte. Las afecciones bucodentales pueden impactar negativamente el rendimiento atlético a través de diversos mecanismos: la inflamación crónica puede reducir la capacidad aeróbica, las infecciones orales pueden comprometer el sistema inmunológico, las maloclusiones y trastornos temporomandibulares pueden alterar la biomecánica corporal, y el dolor orofacial puede interferir con la nutrición y el sueño. Además, las infecciones orales crónicas pueden aumentar el estrés oxidativo sistémico, acelerando la fatiga muscular. Se concluye que la salud bucodental juega un papel crucial en el rendimiento deportivo, siendo un aspecto frecuentemente subestimado. La odontología deportiva es esencial para la prevención y manejo de estas condiciones, mejorando no solo la salud bucal de los atletas, sino también su rendimiento general.  

Takeshi Kurachi, Shinnosuke Chuman, Takuya Suzuki et al.

Abstract Objectives This in vitro study assessed the potential of tooth discoloration by aerosols generated from three heated tobacco products (HTPs) with different specifications: in‐direct heating tobacco system platform 1.0a (IT1.0a), in‐direct heating tobacco system platform 2.0a (IT2.0a), and direct heating tobacco system platform 3.0a (DT3.0a). In addition, three flavor types (regular, menthol, and berry menthol) were selected for each HTP to characterize the effect of flavor types on tooth discoloration. Material and Methods Six bovine tooth samples were exposed directly to aerosols generated from one pack of each HTP: 350 puffs for IT1.0a, 325 puffs for IT2.0a, and 220 puffs for DT3.0a. Six bovine tooth samples were also exposed to air (350 puffs) and smoke generated from one pack of cigarettes (160 puffs) as negative and positive controls, respectively. The color of each tooth sample was measured before and after exposure. The overall color changes were assessed using overall color differences (ΔE) calculated according to the Commission International de I'Eclairage color system. A one‐way analysis of variance followed by Tukey's post hoc test was used to compare ΔE among bovine tooth samples exposed to air, cigarette smoke, and aerosols generated from each HTP. Results ΔE values for tooth samples exposed to air and aerosols generated from the three HTPs (IT1.0a, IT2.0a, and DT3.0a) were significantly lower than ΔE value for tooth samples exposed to cigarette smoke. ΔE values obtained with DT3.0a were significantly higher than those obtained with air‐exposed control samples. However, ΔE values obtained with IT1.0a and IT2.0a were not significantly different from that obtained with air‐exposed control samples. No HTPs showed significant differences in ΔE values among the three flavor types. Conclusions This study showed that HTP aerosols reduce tooth discoloration potential compared with cigarette smoke, regardless of flavor types, and the tooth discoloration potential of the product may depend on product specifications.

Suzely Adas Saliba Moimaz, Jorge Abou Rejaili, Tânia Adas Saliba

Introduction: Dentists are at high risk of contamination by COVID-19 due to the proximity to the patients' oral cavity and airways. Objective: To elucidate the behaviors and adversities experienced by dentists because of the COVID-19 pandemic. Methods: This descriptive study invited 1.811 dentists affiliated with professional associations, dental cooperatives, and health insurance providers from São Paulo State, Brazil, in 2020 of which 473 agreed to participate. The data collection, using Google Forms, included the variables: sociodemographic conditions; characteristics of dental work; level of healthcare and sources of information about the pandemic; changes in the work process, financial impact with personal protective equipment (PPE) and biosafety measures; and consequences of the pandemic in the professional practice. Results: The 473 dentists (40.36±13.44 years), were mostly women (52.22%), had a specialty (55.60%), and were self-employed professionals (73.36%). It was observed that 78.01% of professionals had a reduction in their monthly income. The average of patients treated daily decreased by 35.48%. It was found that 30.44% of professionals had difficulty with the use of PPE, 3.59% contracted COVID-19, and 53.03% decided to postpone the appointment if the patient with suspected or confirmed COVID-19 sought treatment, even in emergencies. The use of high-speed handpieces was reported by most professionals (n=428; 90.48%). Conclusion: Behaviors: dentists used PPE and assigned very high or high levels of precaution about COVID-19. Adversities: dentists reported an increase in operating costs, changes in the work process, a decrease in appointments, and a reduction in the monthly income.

Julia M Galindez, Lamin Juwara, Marisa Cressatti et al.

Background: Parkinson disease (PD) is the second most common neurodegenerative disease, affecting 2% of the population over 65 years of age. PD diagnosis is based on clinical examination and can only be confirmed during autopsy. In 2018, we reported that heme oxygenase-1 (HO-1), an inducible stress response protein important for heme catabolism and implicated in PD pathology, was higher in PD saliva relative to healthy controls, suggesting that salivary HO-1 may serve as a potential biomarker of PD. Objectives: To ascertain whether HO-1 protein levels are elevated in PD saliva relative to degenerative neurological, non-degenerative neurological and healthy controls. Methodology: The study included 307 participants comprising 75 participants with idiopathic PD and 3 control groups: 162 non-neurological, 37 non-PD degenerative neurological, and 33 non-degenerative neurological participants. Salivary HO-1 and total protein concentrations were measured using ELISA and BCA assay, respectively. Receiver operating characteristic (ROC) curves were used to estimate model discrimination. Analyses were adjusted by age, sex, total protein, and relevant comorbidities. Results: Elevated HO-1 concentrations were observed in the PD group and other neurodegenerative conditions compared to subjects with no neurological or non-degenerative neurological conditions. ROC curves using HO-1 levels and covariates yielded areas under the curve above 85% in models for PD or neurodegenerative conditions versus controls. Conclusions: Salivary HO-1 concentrations in combination with covariates may provide a biomarker signature that distinguishes patients with neurodegenerative conditions from persons without. Classification of evidence: This study provides Class III evidence that salivary HO-1 multivariable models can distinguish neurodegenerative conditions.

Karla Coello Holguín, Luis Arcentales Sanchez

Objetivo: Describir las opciones de tratamiento que son utilizadas para lograr la alineación de las piezas dentarias por medio de aparatología ortodóntica. La oclusión está clasificada por Angle, definiendo 3 Clases de oclusiones, que son: Clase I, Clase II y Clase III. Denominadas años después por Lisher la clase I correspondiente a una neutroclusión por mostrar una correlación neutra entre los molares, la clase II denominada distoclusión porque el molar inferior ocluye por distal de la posición determinada normal, y la clase III que corresponde a la mesioclusión que se la determina por la posición del molar inferior mesializada correspondientemente de la posición normal. A pesar de que la Clase I está determinada como neutroclusión, esta no siempre va a presentar armonía en todos los que la presente. La Clase I puede estar alterada por la presencia de factores generales y locales, como anomalías de número, de forma, de tamaño, y de erupción. El tratamiento de las maloclusiones en pacientes Clase I puede tener un resultado estable y favorecer, mejor que en las Clases II y III. Conclusión: Existen varias opciones de tratamiento para lograr una correcta alineación de las piezas dentarias, entre las que están el stripping, la extracción de premolares, aparatología ortopédica, entre otras.

Yilmaz Melis, Balci Senay, Kocak Topbas Nazan et al.

The aim of the study is to analyze the association of different bitter and sweet gene receptor polymorphisms and bitter and sweet food consumption on formation of dental caries in Turkish adult population.

Fatemeh Zovari, Hadi Parsian, Ali Bijani et al.

Objective. In menopause, reduction of estrogen hormone affects oxidative stress process in serum. Oxidative stress in saliva plays a significant role in the pathogenesis of oral diseases. The aim of this study was to investigate the total antioxidant capacity and lipid peroxidation in the serum and saliva of premenopausal and postmenopausal women. Methods. In this case control study, 50 postmenopausal women (case group) and 48 premenopausal women (control group) were selected. The unstimulated whole saliva and serum of the postmenopausal and premenopausal women were collected. The total antioxidant capacity (TAC) of the saliva and serum was measured by ferric reducing antioxidant power (FRAP). Also, malondialdehyde (MDA) was measured by thiobarbituric acid reactive substance (TBARS) method for serum and saliva. Then, the obtained data were analyzed by SPSS 17, whereby Mann–Whitney test and Spearman’s correlation test were used. P<0.05 was considered statistically significant. Results. The postmenopausal group had significantly lower mean serum TAC and higher mean serum MDA than the control group (P<0<001 and P<0.01, respectively). The mean salivary TAC and MDA, however, did not differ significantly between the case and control group (P=0.64 and P=0.08, respectively). Conclusion. In postmenopausal women, with elevation of serum MDA and reduction of serum TAC, the extent of serum oxidative stress grows, but MDA and TAC levels of saliva do not change.

Soyoung Hwang, Dong Min Shin, Jeong Hee Hong

Disulfiram has been used in the treatment of alcoholism and exhibits an anti-tumor effect. However, the intracellular mechanism of anti-tumor activity of Disulfiram remains unclear. In this study, we focused on the modulatory role of Disulfiram via oncogenic factor carbonic anhydrase CA12 and its associated transporter anion exchanger AE2 in lung cancer cell line A549. The surface expression of CA12 and AE2 were decreased by Disulfiram treatment with a time-dependent manner. Disulfiram treatment did not alter the expression of Na⁺-bicarbonate cotransporters, nor did it affect autophagy regulation. The chloride bicarbonate exchanger activity of A549 cells was reduced by Disulfiram treatment in a time-dependent manner without change in the resting pH level. The expression and activity of AE2 and the expression of CA12 were also reduced by Disulfiram treatment in the breast cancer cell line. An invasion assay and cell migration assay revealed that Disulfiram attenuated the invasion and migration of A549 cells. In conclusion, the attenuation of AE2 and its supportive enzyme CA12, and the inhibitory effect on cell migration by Disulfiram treatment in cancer cells provided the molecular evidence supporting the potential of Disulfiram as an anticancer agent.

Kimura A, Yamaguchi K, Tohara H et al.

Atsushi Kimura,1 Kohei Yamaguchi,2,3 Haruka Tohara,3 Yusuke Sato,4 Naoko Sawada,4 Yasuhide Nakagawa,4 Yukako Matsuda,2,5 Motoharu Inoue,2,5 Kazuhiro Tamaki2,4 1College of Risk Management, Nihon University, Setagaya-ku, Tokyo, Japan; 2Dentistry Nanohana Clinic, Medical Corporation Kanjinkai, Nishitama-gun, Tokyo, Japan; 3Department of Gerodontology and Oral Rehabilitation, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan; 4Geriatric Health Services Facility Nanohana, Medical Corporation Kanjinkai, Nishitama-gun, Tokyo, Japan; 5Department of Dysphasia Rehabilitation, Nihon University of Dentistry, Chiyoda-Ku, Tokyo, JapanCorrespondence: Atsushi KimuraCollege of Risk Management, Nihon University, 3-34-1 Shimouma, Setagaya-ku, Tokyo 154-8513, JapanTel +81 3 6453 1600Fax +81 3 6453 1630Email kimura.atsushi@nihon-u.ac.jpKazuhiro TamakiGeriatric Health Services Facility Nanohana, Medical Corporation Kanjinkai, 454 Tonogaya, Mizuho-machi, Nishitama-gun, Tokyo 190-1212, JapanTel +81 42 568 5111Fax +81 42 568 5127Email tamakikazuhiro@g.kanjinkai.netPurpose: The previous study demonstrated that the addition of a sauce is an effective means of influencing the consumption of finger foods among French elderly people with dementia. However, it is unclear the relative importance of low-level sensory factors such as flavor and a semi-solid nature and high-level cognitive factors such as memory stimulation and familiarity to the effect of the addition of sauce on food intake. The present study investigated whether the addition of sauce affects finger-snack intake among Japanese elderly people with dementia who were not familiar with sauce dipping.Patients And Methods: A total of 21 patients with dementia who were recruited in a nursing home in Tokyo received a plate of cut baumkuchen (a very thinly layered German roll cake), which had pieces of baumkuchen both with and without sauce, at their afternoon snack time. The amount of food intake and the first choice between options were measured for each participant. We used chocolate (in Experiment 1, n = 21) and agave (Experiment 2, n =14) syrups as sauce samples.Results: Results of both experiments demonstrate that snack consumption was greater for the with-sauce options than for the without-sauce options. A 90.5% of the participants in Experiment 1 and 64.3% of participants in Experiment 2 ate more snacks with sauce than without sauce.Conclusion: These findings imply that low-level sensory factors such as flavor and a semi-solid nature contribute relatively more strongly to the enhancement of food consumption with the addition of sauce than do high-level cognitive factors such as memory stimulation and familiarity, because Japanese elderly people are not always familiar with the custom of wiping up the sauce with food.Keywords: food consumption, dementia, under nutrition, food improvement, sauce

Amit Manohar Reche, Shrutika Dhanrajji Chordiya, Sakshi Pradeep Joshi et al.

Aim: The aim of this study was to assess the prevalence of dental caries and evaluate oral health-related quality of life (QoL) in patients with cleft lip and palate (CLP) in Vidarbha region. Settings and Design: A cross-sectional questionnaire study was conducted in the Department of Public Health Dentistry of our institute. The sample was divided into three groups. Subjects and Methods: Group A (110) patients with unilateral CLP (UCLP), Group B (110) patients with bilateral CLP (BCLP), and Group C (150) control group. From self-administered questionnaire, the patients were asked 10 questions based on eating, speaking, toothbrushing, sleeping, smiling, emotional status, carrying out work, and social contact and rated as 0, 1, 2, and 3 (no problem, mild, moderate, and severe). Statistical Analysis Used: ANOVA and Pearson's correlation tests were performed. Results: According to the results, there is no statistical difference for decayed, missing, and filled teeth score seen between UCLP and BCLP patients; however, there is significant difference (<0.001) seen between the cleft patients and control group. According to questionnaire result, the patients with bilateral cleft experienced more difficulty while eating, speaking, smiling, and maintaining social contact as compared to the control group. Conclusion: Patients suffering from CLP showed higher caries prevalence compared to the control group; on the other hand, negative impact has been seen on the QoL of CLP patients.

Alexis Ioannidis, Spyridon N. Papageorgiou, Iosif Sifakakis et al.

Abstract Background The purpose of the study is to investigate the effect of the bonding procedure on the mechanical properties of human enamel. Methods A total of 20 extracted human premolars were included in this study, with the half of each tooth acting as its own internal control. Embedded and horizontally cut specimens were prepared, and two bucco-orally zones were separated. The first enamel zone of each tooth remained untreated. The opposing zone was subjected to simulated bonding and debonding, including etching with 37% phosphoric acid, bonding with primer and flowable composite resin, and subsequent removal of the composite with an adhesive removal bur. The properties tested were (a) elemental composition by energy-dispersive X-ray analysis, (b) mechanical properties of specimens by instrumented indentation testing (Martens hardness, elastic modulus, and elastic index), (c) enamel morphology by low-vacuum scanning electron microscopy, and (d) molecular composition by Raman microspectroscopy. Statistical analysis was performed by one-way mixed-effects analysis of variance at a = 0.05. Results No significant differences could be found in the mechanical properties (Martens hardness, elastic modulus, and elastic index) and elemental composition of intact and treated enamel, with the possible exception of Si traces, which were found only in the latter. Raman analysis revealed no differences between the two surface states while shallow grooves and parallel lines were found on the surface of treated enamel by SEM analysis. Conclusions Under the limitations of the conditions of the study, there were no mechanical properties’ alterations on enamel subjected to orthodontic bonding.

Rafaella de Souza LEÃO, Juliana Raposo Souto MAIOR, Cleidiel Aparecido de Araújo LEMOS et al.

Abstract Polymethyl methacrylate (PMMA) has been considered a suitable material for cranioplasty. However, no consensus has been reached concerning the best material for cranioplasty with regard to minimizing complications. Thus, this systematic review and meta-analysis aimed to compare the complication rates of PMMA with those of autologous bone and titanium mesh. This review was registered with PROSPERO (CRD42016042725). Systematic searches were conducted on PubMed/MEDLINE, Scopus, and Web of Science. The focus question was, “Do PMMA prostheses used in cranioplasty have complications rates similar to those of autologous bone and titanium mesh?” A meta-analysis of complication rates was performed on the basis of dichotomous outcomes assessed by risk ratio (RR) with corresponding 95% confidence intervals (CI). From 1014 data sources, 11 articles were selected according to eligibility criteria. These articles involved 1,256 individuals and 1,278 cranioplasties using autologous bone (n = 408), PMMA (n = 379), or titanium (n = 151). The follow-up period ranged from 63 days to 54.3 months. No difference was observed between the complication rates of PMMA and autologous bone (p = 0.94; RR, 0.98; 95%CI, 0.54–1.75) or between PMMA and titanium (p = 0.38; RR, 1.59; 95%CI, 0.57–4.48). Sub-analysis of the reasons for craniotomy (trauma/non-trauma) was conducted, which revealed no significant difference (p = 0.91; RR, 0.95; 95%CI, 0.37–2.42). The meta-analysis indicated that the use of PMMA yields complication rates that are near those of autologous bone and titanium mesh.

N. F. Plavunov, V. A. Kadyshev, T. Ya. Chernobrovkina et al.

Erysipelas is one of the first places on the prevalence of infectious disease after acute respiratory and intestinal infections, viral hepatitis. Currently, in most cases erysipelas is caused by beta-hemolytic group A Streptococcus bacterium, but in some cases could be due to co-infection with Staphylococcus aureus. The pathogenesis of erysipelas is characterized by impaired tissue immunity, cellular and humoral immunity deficiency, hypersensivity to hemolytic streptococci group A (Lansfeld). Chronic recurrent erysipelas refers to endogenous infection caused by intradermal and intra-macrophage maintaining L-forms of Streptococcus, and biological damage caused by excess production of cytokines by T-lymphocytes and mononuclear cells. The disease is characterized by increased cases with primary and severe hemorrhagic forms (over 60%), a tendency to develop recurrent erysipelas (30 to 40%), slow regenerative process in the focus of inflammation, the multiplicity of the differential diagnosis. Risk factors of the erysipelas are the disruption of the skin barrier, fungal skin infections, emotional stress, body hypothermia or overheating. Women suffer from erysipelas more often than men. Adults over age 40 years and older are more likely to develop erysipelas in more than 60% of cases. Erysipelas is characterized by seasonality- rise in the incidence observed in spring and autumn than other streptococcal infections. Depending on the lack of treatment efficacy in resolving symptoms of erysipelas, impaired prevention of disease recurrence, recommended treatment by scientists involves antibiotics with immunomodulation therapy and laser therapy.

Editorial

The authors and their affiliations were listed as follows: Ranko Golijanin*†, Bojan Kujundžić†, Zoran Milosavljević‡, Dragan R. Milovanovi槆†, Zlatibor Andjelković║, Miroslav Obrenović¶, Radivoje Nikolić**†† *Department of Dentistry, ‡Department of Histology and Embriology, §Department of Pharmacology and Toxicology, **Department of Surgery, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; †Faculty of Dental Medicine, ¶Faculty of Medicine, University of East Sarajevo, Foča, Republic of Srpska, Bosnia and Herzegovina; ††Clinical Center “Kragujevac”, Kragujevac, Serbia Listed the authors and their affiliations should read as: Ranko Golijanin*†, Bojan Kujundžić†, Zoran Milosavljević‡, Dragan R. Milovanovi槆†, Zlatibor Andjelković║, Miroslav Obrenović¶, Radivoje Nikolić**†† *Department of Dentistry, ‡Department of Histology and Embriology, §Department of Pharmacology and Toxicology, **Department of Surgery, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; ║Department of Histology, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia; †Faculty of Dental Medicine, ¶Faculty of Medicine, University of East Sarajevo, Foča, Republic of Srpska, Bosnia and Herzegovina; ††Clinical Center “Kragujevac”, Kragujevac, Serbia <br><br><font color="red"><b> Link to the corrected article <u><a href="http://dx.doi.org/10.2298/VSP130627076G">10.2298/VSP130627076G</a></b></u>

Isabela Priscila Cardoso da Silva, Tatiana Satomi Kunihira, Victor Bomfim Pinheiro et al.

No meio odontológico, sabe-se da prevalência mundial da doença periodontal, principalmente em adultos. Esta infecção bacteriana, que envolve os tecidos que circundam os dentes, é a maior responsável por perdas dentárias. Devido à falta de informação da população sobre o assunto, há necessidade de orientar melhor as pessoas a identificarem os principais sinais clínicos relacionados ao diagnóstico das doenças periodontais e, conseqüentemente, a buscarem o tratamento adequado o mais imediato possível. Assim, foi confeccionado pelos alunos do 2º período de odontologia da Universidade Severino Sombra, um folheto educativo com figuras ilustrativas do periodonto normal (saudável) com suas estruturas e do periodonto doente (gengivite até periodontite). Além disso, um conteúdo explicativo sobre o que se entende por doença periodontal, sua causa, fatores de risco, evolução da doença; o tratamento e a prevenção também se encontram inseridos. Os esclarecimentos contidos são de suma importância, principalmente, para que os pacientes entendam desde o início a instalação, desenvolvimento e progressão das doenças periodontais e se sintam motivados para um maior cuidado com sua higiene bucal, mais particularmente com controle do biofilme dental. A ausência de dor e o fato dos primeiros sinais clínicos envolvidos não serem identificados pela maioria de seus portadores fazem com que esta condição seja negligenciada (muito diferente da cárie dentária) até que sinais da doença avançada, tais como mobilidade dentária e abscessos estejam presentes, aumentando a severidade da doença e piorando o prognóstico da mesma. Assim sendo, faz-se necessário divulgar todas essas informações ao maior número de pessoas e reforçar a relevância da imprescindibilidade das visitas regulares ao cirurgião dentista, que pode, através do exame clínico e radiográfico diagnosticar, prevenir e tratar prontamente a referida infecção, devolvendo conforto, função, bem estar e principalmente saúde aos pacientes.

Martin Kyncl, Martin Koci, Lea Ptackova et al.

Background: This study evaluated the accuracy of postnatal computed tomography (CT) imaging in the identification of congenital bronchopulmonary malformation (BPM) in comparison with histopathological analysis. Methods: CT scans of prenatally diagnosed BPMs from 24 patients with available histology were analysed retrospectively. The CT images were reviewed blinded to histological findings by two radiologists. Specific diagnosis was assigned based on predetermined criteria. The accuracy of CT was evaluated. Results: The agreement rate in CT diagnosis between two radiologists was 100%. In 75% the lesions were located in the lower lobes. An overlap of 71% in CT and histopathological diagnoses was reached. The least matching diagnosis was type 2 CPAM. Conclusion: Contrast enhanced chest CT is very accurate in characterizing the BPM spectrum and provides important information on lesion type and structure.