Text-to-Video (T2V) generators such as Sora raise concerns about whether generated content reflects societal bias. We extend embedding-association tests from words and images to video by introducing the Video Embedding Association Test (VEAT) and Single-Category VEAT (SC-VEAT). We validate these methods by reproducing the direction and magnitude of associations from widely used baselines, including Implicit Association Test (IAT) scenarios and OASIS image categories. We then quantify race (African American vs. European American) and gender (women vs. men) associations with valence (pleasant vs. unpleasant) across 17 occupations and 7 awards. Sora videos associate European Americans and women more with pleasantness (both d>0.8). Effect sizes correlate with real-world demographic distributions: percent men and White in occupations (r=0.93, r=0.83) and percent male and non-Black among award recipients (r=0.88, r=0.99). Applying explicit debiasing prompts generally reduces effect-size magnitudes, but can backfire: two Black-associated occupations (janitor, postal service) become more Black-associated after debiasing. Together, these results reveal that easily accessible T2V generators can actually amplify representational harms if not rigorously evaluated and responsibly deployed.
This study examines long-term mortality effects of combat exposure using the Vietnam War draft lottery as a quasi-experiment. We validate the lottery by analyzing combat fatalities, revealing that 1951-1952 cohorts had notably fewer lottery-induced deployments than 1950, limiting detectable long-term mortality impacts at the cohort level. Using deceased-only datasets, we invert standard identification by modeling draft eligibility as the outcome. We find significant excess mortality among Black men in the 1950 cohort (1.09\%, approximately 2,700 additional deaths), and null effects in later cohorts. Findings suggest that pooling cohorts with limited combat exposure may prevent detection of true treatment effects at cohort levels.
Engaging in meaningful collaborations with peers, both inside and outside the classroom, can greatly enhance students' understanding of physics and other STEM disciplines. We analyzed the characteristics of women and men who typically worked alone versus those who collaborated with peers in a calculus-based introductory physics course comparing pre pandemic traditional in-person classes to Zoom based pandemic classes. We discuss our findings by considering students' prior academic preparation, their physics grades and physics self-efficacy, as well as their perceptions of how effective peer collaboration is for their physics self-efficacy. We also compared our results to the first-semester algebra-based introductory physics course.
This paper is the first to provide causal evidence of gender differences in healthcare utilisation to better understand the male-female health-survival paradox, where women live longer but experience worse health outcomes. Using rich Danish administrative healthcare data, we apply a staggered difference-in-differences approach that exploits the randomness in treatment timing to estimate the causal impact of adverse health shocks, such as non-fatal heart attacks or strokes, on healthcare use. Our findings suggest that men consistently use more healthcare than women, highlighting the underlying factors driving gender disparities in health outcomes. These insights contribute to the broader discourse on healthcare equity and inform policy interventions aimed at addressing these imbalances.
Incels are an extremist online community of men who believe in an ideology rooted in misogyny, racism, the glorification of violence, and dehumanization. In their online forums, they use an extensive, evolving cryptolect - a set of ingroup terms that have meaning within the group, reflect the ideology, demonstrate membership in the community, and are difficult for outsiders to understand. This paper presents a lexicon with terms and definitions for common incel root words, prefixes, and affixes. The lexicon is text-based for use in automated analysis and is derived via a Qualitative Content Analysis of the most frequent incel words, their structure, and their meaning on five of the most active incel communities from 2016 to 2023. This lexicon will support future work examining radicalization and deradicalization/disengagement within the community.
<p>Evidence suggests that gay, bisexual and other men who have sex with men (MSM) score higher than heterosexual-identifying men on disordered eating symptomology (DES). This exploratory study examined if the following psychosocial factors were associated with DES among a diverse sample of MSM: race, age, sexual identity, sexual risk, substance use, depression, history of childhood sexual abuse (CSA) and internalized homophobia. Using cross sectional data collected at "Pride Toronto 2008" (N = 383), multivariate analysis revealed the following factors to be associated with DES: CSA, depression, being White (vs. Black or Asian), being younger, and engaging in behaviours to increase muscle mass. These results may inform the development of useful and efficacious interventions to reduce the risks associated with body dissatisfaction and DES among MSM.</p>
Ichiro Okada, Toru Hifumi, Hisashi Yoneyama
et al.
Abstract Background A team approach is essential for effective trauma management. Close collaboration between interventional radiologists and surgeons during the initial management of trauma patients is important for prompt and accurate trauma care. This study aimed to determine whether trauma patients benefit from close collaboration between interventional radiology (IR) and surgical teams during the primary trauma survey. Methods A retrospective observational study was conducted between 2014 and 2021 at a single institution. Patients were assigned to an embolization group (EG), a surgery group (SG), or a combination group (CG) according to their treatment. The primary and secondary outcomes were survival at hospital discharge compared with the probability of survival (Ps) and the time course of treatment. Results The analysis included 197 patients, consisting of 135 men and 62 women, with a median age of 56 [IQR, 38–72] years and an injury severity score of 20 [10–29]. The EG, SG, and CG included 114, 48, and 35 patients, respectively. Differences in organ injury patterns were observed between the three groups. In-hospital survival rates in all three groups were higher than the Ps. In particular, the survival rate in the CG was 15.5% higher than the Ps (95% CI: 7.5–23.6%; p < 0.001). In the CG, the median time for starting the initial procedure was 53 [37–79] min and the procedure times for IR and surgery were 48 [29–72] min and 63 [35–94] min, respectively. Those times were significantly shorter among three groups. Conclusion Close collaboration between IR and surgical teams, including the primary survey, improves the survival of severe trauma patients who require both IR procedures and surgeries by improving appropriate treatment selection and reducing the time process.
Special situations and conditions, Medical emergencies. Critical care. Intensive care. First aid
Abstract Background and objectives Associations between fruit and vegetable consumption and mental health have been observed, but studies comparing different types of plant foods are sparse. This study among Finnish municipal employees examined associations of the consumption of a range of different plant foods with emotional well-being (EWB). Data and methods We used survey data from the Helsinki Health Study conducted in 2017 among 19–39-year-old employees of the City of Helsinki, Finland (N = 5898, response rate 51.5%, 80% women). Consumption of plant foods, including fruit, berries, fresh and cooked vegetables and wholegrain bread, was measured by a food frequency questionnaire and dichotomised into daily/non-daily consumption. The EWB scale of the RAND-36 questionnaire was dichotomised, with the lowest quartile indicating ‘poor EWB’ and the three higher quartiles indicating ‘good EWB’. We used logistic regression for analysing the associations between plant food consumption and EWB. Analyses were sex-stratified and age, socioeconomic circumstances and psychosocial working conditions were adjusted for. Results Prevalence of daily consumption of plant foods varied from 25% for berries and cooked vegetables to 70% for fresh vegetables. Daily consumption was associated with good EWB among both women and men. The strongest age-adjusted association was found for fresh vegetables, with women (OR 1.48, 95% CI 1.27–1.74) and men (OR 1.86, CI 1.37–2.52) with daily consumption having clearly higher odds of good EWB compared to non-daily consumers. Associations slightly attenuated but mostly remained after adjusting for socioeconomic circumstances and working conditions. Conclusions More frequent plant food consumption was associated with good EWB. Thus, the results support the need for interventions that investigate whether the promotion of plant food consumption could show potential mental health benefits among employees.
Nutrition. Foods and food supply, Food processing and manufacture
Valentin-Gabriel Soumah, Prashanth Rao, Philipp Eibl
et al.
We present the Radar de Parité, an automated Natural Language Processing (NLP) system that measures the proportion of women and men quoted daily in six Canadian French-language media outlets. We outline the system's architecture and detail the challenges we overcame to address French-specific issues, in particular regarding coreference resolution, a new contribution to the NLP literature on French. We also showcase statistics covering over one year's worth of data (282,512 news articles). Our results highlight the underrepresentation of women in news stories, while also illustrating the application of modern NLP methods to measure gender representation and address societal issues.
Objectives: To examine sex differences in the associations between vascular risk factors and 6-year changes in the volume of white matter hyperintensities (WMH), and between changes in WMH volumes and changes in cognitive performance, in a cohort of non-demented older adults. Methods: WMH volumes at 3 time-points (baseline, and 2- and 6-year follow-up) were automatically quantified in participants of Sydney Memory and Ageing Study (N = 605; age range = 70-92 years; 54.78% female). Linear mixed models were applied to examine the effects of vascular risk factors and cognitive consequences of the progression of WMH, as well as the sex moderation effects in the associations. Results: Total (TWMH), periventricular (PVWMH), and deep (DWMH) WMH volumes increased by 9.47%, 7.70%, and 11.78% per year, respectively. No sex differences were found in WMH progression rates. After Bonferroni correction, increases in PVWMH volumes over time were associated with decline in global cognition, especially in visuospatial and memory domains. Men with more increases in PVWMH volumes over time had greater declines in visuospatial abilities. Moreover, higher average TWMH volumes across time-points were associated with poorer average performance in processing speed and executive function domains across time. Higher average PVWMH volumes across time-points were also associated with worse average performance in the executive function domain over time, among women but not men. Conclusion: The findings highlighted sex differences in the associations between WMH progression and cognition decline over time, suggesting sex-specific strategies in managing WMH accumulations in ageing. Keywords: Cerebral small vessel disease, white matter hyperintensities, sex differences, brain ageing, cognitive decline.
Sorting a permutation by reversals is a famous problem in genome rearrangements. Since 1997, quite some biological evidence were found that in many genomes the reversed regions are usually flanked by a pair of inverted repeats. This type of reversals are called symmetric reversals, which, unfortunately, were largely ignored until recently. In this paper, we investigate the problem of sorting by symmetric reversals, which requires a series of symmetric reversals to transform one chromosome $A$ into the another chromosome $B$. The decision problem of sorting by symmetric reversals is referred to as {\em SSR} (when the input chromosomes $A$ and $B$ are given, we use {\em SSR(A,B)}) and the corresponding optimization version (i.e., when the answer for {\em SSR(A,B)} is yes, using the minimum number of symmetric reversals to convert $A$ to $B$), is referred to as {\em SMSR(A,B)}. The main results of this paper are summarized as follows, where the input is a pair of chromosomes $A$ and $B$ with $n$ repeats. (1) We present an $O(n^2)$ time algorithm to solve the decision problem {\em SSR(A,B)}, i.e., determine whether a chromosome $A$ can be transformed into $B$ by a series of symmetric reversals. (2) We design an $O(n^2)$ time algorithm for a special 2-balanced case of {\em SMSR(A,B)}, where chromosomes $A$ and $B$ both have duplication number 2 and every repeat appears twice in different orientations in $A$ and $B$. (3) We show that SMSR is NP-hard even if the duplication number of the input chromosomes are at most 2, hence showing that the above positive optimization result is the best possible. As a by-product, we show that the \emph{minimum Steiner tree} problem on \emph{circle graphs} is NP-hard, settling the complexity status of a 38-year old open problem.
OBJECTIVE. To determine the clinical, X-ray examination features in the newly detected sarcoidosis in HIV-infected patients.
MATERIALS AND METHODS. HIV-infected patients (6 women, 10 men, middle age – 43.5, range – 25-62 years) with the newly detected sarcoidosis had been observed during 2006-2022 years. The level of CD4+ cells, signs or symptoms of disease, dependence of development of sarcoidosis on the terms of setting of antiretroviral therapy were considered. The following criteria were evaluated during X-ray examination and computer tomography (CТ): lymphadenopathy, pulmonary knots, focal consolidations, reticular or grainy changes, symptom of ground glass, cysts or fibrosis.
RESULTS AND DISCUSSION. A middle interval between two diagnoses was 1 year. A level of CD4+ cells was 424/µl (range – 34-680 cells/µl). All patients had pulmonary signs or symptoms at diagnosis giving of sarcoidosis. X-ray examination showed a lymphadenopathy, pulmonary knots, focal consolidations, reticular changes, symptom of ground glass, cysts. CТ showed a lymphadenopathy, knots, bulge of intersegments partitions, focal consolidations, reticular dimnesses, symptom of ground glass and cysts. All patients received a course of treatment based on corticosteroids. The result of the treatment was assessed as positive. No relapses of the disease were found.
CONCLUSIONS. The X-ray and clinical features in the newly detected pulmonary sarcoidosis in HIV-infected patients are analogical to those in patients without HIV-infection. A level of CD4+ cells in most patients was >200/µl. Development of sarcoidosis depends from conservation or updating of level of CD4+ of lymph cells, and mostly it exceeds 200 cells/µl. A treatment with corticosteroids promotes recovery.
Joshua A. Bell, Tom G. Richardson, Qin Wang
et al.
Summary: Background: The direct effects of general adiposity (body mass index (BMI)) and central adiposity (waist-to-hip-ratio (WHR)) on circulating lipoproteins, lipids, and metabolites are unknown. Methods: We used new metabolic data from UK Biobank (N=109,532, a five-fold higher N over previous studies). EDTA-plasma was used to quantify 249 traits with nuclear-magnetic-resonance spectroscopy including subclass-specific lipoprotein concentrations and lipid content, plus pre-glycemic and inflammatory metabolites. We used univariable and multivariable two-stage least-squares regression models with genetic risk scores for BMI and WHR as instruments to estimate total (unadjusted) and direct (mutually-adjusted) effects of BMI and WHR on metabolic traits; plus effects on statin use and interaction by sex, statin use, and age (proxy for medication use). Findings: Higher BMI decreased apolipoprotein B and low-density lipoprotein cholesterol (LDL-C) before and after WHR-adjustment, whilst BMI increased triglycerides only before WHR-adjustment. These effects of WHR were larger and BMI-independent. Direct effects differed markedly by sex, e.g., triglycerides increased only with BMI among men, and only with WHR among women. Adiposity measures increased statin use and showed metabolic effects which differed by statin use and age. Among the youngest (38-53y, statins-5%), BMI and WHR (per-SD) increased LDL-C (total effects: 0.04-SD, 95%CI=-0.01,0.08 and 0.10-SD, 95%CI=0.02,0.17 respectively), but only WHR directly. Among the oldest (63-73y, statins-29%), BMI and WHR directly lowered LDL-C (-0.19-SD, 95%CI=-0.27,-0.11 and -0.05-SD, 95%CI=-0.16,0.06 respectively). Interpretation: Excess adiposity likely raises atherogenic lipid and metabolite levels exclusively via adiposity stored centrally, particularly among women. Apparent effects of adiposity on lowering LDL-C are likely explained by an effect of adiposity on statin use. Funding: UK Medical Research Council; British Heart Foundation; Novo Nordisk; National Institute for Health Research; Wellcome Trust; Cancer Research UK
Understanding differences in hospital case-fatality rates (HCFRs) of coronavirus disease (COVID-19) may help evaluate its severity and the capacity of the healthcare system to reduce mortality. We examined the variability in HCFRs of COVID-19 in relation to spatial inequalities in socioeconomic factors across the city of Sao Paulo, Brazil. We found that HCFRs were higher for men and for individuals aged 60 years and older. Our models identified per capita income as a significant factor that is negatively associated with the HCFRs of COVID-19, even after adjusting by age, sex and presence of risk factors.
Alexander G. Chkhartishvili, Dmitry A. Gubanov, Ivan V. Kozitsin
This cross-sectional study characterizes users' attitudes towards the face mask requirements introduced by the Russian government as a response to the COVID-19 pandemic. We study how they relate to other users' characteristics such as age, gender, and political attitudes. Our results indicate that men and elder individuals - demographic groups that are most vulnerable to COVID-19 -- underestimate the benefits of wearing face masks. We also discovered that users in opposition to the Russian government highly approve of this anti-COVID-19 measure -- an oppositionist will approve of the face mask requirements with the probability of 0.95. For those who support the Russian government, the odds of approval are merely 0.45.
I am presenting a first-ever scientific collection of short sayings on probability and statistics expressed by most various men of science, many classics included, from antiquity to Kepler to our time. Quite understandably, the reader will find here no mathematical formulas and in some instances he will miss a worthy subject. Markov chains provide a good example: their inventor had not said anything about them suitable for my goal. Nevertheless, the scope of the collected dictums is amazingly broad which reflects both the discussions concerning the lack of a solid foundation of probability theory until the 1930s and the great extent of applications of probability and statistics. And I have also included two related and most important topics, the treatment of observations and randomness.
Cécile R L P N Jeukens, Hub Boere, Bart A J M Wagemans
et al.
Objective High radiation exposure is a concern because of the association with cancer. The objective was to determine the probability of receiving a high radiation dose from CT (from one or more examinations within a 5-year period) and to assess the clinical context by evaluating clinical indications in the high-dose patient group.Design Observational cohort study. Effective radiation dose received from one or more CT examinations within a predefined 5-year calendar period was assessed for each patient.Setting Hospital setting.Participants All patients undergoing a diagnostic CT examination between July 2013 and July 2018 at the Maastricht University Medical Center.Primary and secondary outcome measures The primary outcome was the probability of receiving a high effective dose, defined as ≥100 mSv, from one or more CT examinations within 5 years as derived from a time-to-event analysis. Secondary outcomes were the clinical indication for the initial scan of patients receiving a high effective dose.Results 100 672 CT examinations were performed among 49 978 patients including 482 (1%) who received a high radiation dose. The estimated probability of a high effective dose from a single examination is low (0.002% (95% CI 0.00% to 0.01%)). The 4.5-year probability of receiving a high cumulative effective dose was 1.9% (95% CI 1.6% to 2.2%) for women and 1.5% (95% CI 1.3% to 1.7%) for men. The probability was highest in age categories between 51 and 74 years. A total of 2711 (5.5%) of patients underwent more than six CT examinations, and the probability of receiving a high effective dose was 16%. Among patients who received a high effective dose, most indications (80%) were oncology related.Conclusions The probability of receiving a high radiation dose from CT examinations is small but not negligible. In the majority (80%) of high effective dose receiving patients, the indication for the initial CT scan was oncology related.