Oxidation of polyaniline-derived carbon using microwaves for adsorptive removal of pharmaceuticals with an amino group
Dae Sung Kwon, Minyoung Yoon, Sung Hwa Jhung
Carbonaceous materials, especially oxidized ones, have been frequently used as adsorbents. Oxidation of carbons has usually been carried out using ammonium persulfate/H2SO4 solution under electric heating. In this work, polyaniline-derived carbons were oxidized with both the conventional method and HNO3 under microwaves. The obtained carbons, after thorough characterization, were applied to the adsorptive purification of water polluted with emerging contaminants, especially basic pharmaceuticals with amino groups (like atenolol (ATNL) and diphenhydramine (DPHA)). The carbon oxidized under microwave was much more effective in the adsorption than the carbon oxidized by the conventional method using electric heating. Both the adsorbed quantities and adsorption kinetic constants increased with increasing oxidation (by microwaves) temperatures up to 100 °C. The best performing MPDC(100) was recyclable and highly competitive in the adsorption of ATNL and DPHA. The mechanism of ATNL and DPHA adsorptions over MPDC(100) was investigated by checking surface charge and adsorbed quantities under wide pH conditions. Electrostatic interaction with π-π interaction and hydrogen bonding (adsorbent: hydrogen-acceptor) was the major mechanism for the effective adsorption over MPDC(100). Finally, porous carbon with a high concentration of anionic sites like carboxylates can be suggested as an effective adsorbent to remove basic pharmaceuticals with amino groups.
Hazardous substances and their disposal
Rational design of CYP120A1 variants and eco-friendly alternatives for enhanced bioremediation of sulfonamide antibiotics
Miaomiao Li, Xu Guan, Xiaoxia Yu
et al.
Bioremediation mediated by cytochrome P450 enzymes represents an effective strategy for the removal of Sulfonamides (SAs). However, the inherent limitations in the thermostability and catalytic activity of wild-type enzymes result in suboptimal remediation efficiency. Therefore, the development of highly efficient degradative enzymes is crucial for mitigating SAs pollution. Additionally, identifying environmentally friendly alternatives with lower toxicity is beneficial for source control of SAs. This work adopts an integrated strategy that combines bioremediation and source control. Utilizing multiple computational strategies, we rationally designed and screened novel high-efficiency enzyme variants of CYP120A1 specifically targeting SAs degradation, and concurrently evaluated the molecular properties of pollutants to design new green alternatives. This study successfully identified 18 single-mutation enzyme candidates with enhanced thermostability and catalytic activity. Furthermore, we designed three green alternatives, SDZ-13, SDZ-19, and SDZ-27, which exhibit lower toxicity and significantly improved binding affinity with the degradative enzymes. However, accurate and rapid identification of mutation sites and practical application of eco-friendly molecular design remain significant challenges for future research. This work provides theoretical support for the development of efficient degradative enzymes and the design of sustainable alternative compounds, contributing to the advancement of emerging pollutants pollution control strategies.
Hazardous substances and their disposal
Assessment and Comparison of Distress and Suicidal Behavior in Medical and Paramedical Students
Mitra Safa, Maryam Sadat Mirenayat, Mohsen Abedi
et al.
Background: The sudden outbreak of coronavirus disease in 2019 resulted in major changes in mental health of healthcare workers as the front line of fighting against thedisease. Medical students who were from the main members of healthcare workers suffered double pressure. The goal of current study was evaluation of suicidal behavior and psychological distress in medical and paramedical students to determine the mental health status of these students by identifying the mentioned factors.
Methods: This is an applied, comparative and cross-sectional study. The sample members (302 participants) were selected by accessible method from medical students in Masih Daneshvari Hospital in 2023-2024. The Kessler Psychological Distress Scale (K6) and Suicide Behaviors Questionnaire-Revised (SBQ-R) were completed by all the participants. Data were analyzed by T, Chi square, Pearson and ANOVA tests by SPSS-22.
Results: The highest and lowest risk of suicide was between interns (M=7.37) and fellowships (M=3.71), respectively. The highest and the lowest score of psychological distress was between interns (M=10.82) and paramedical PhD students (M=6.9), respectively. Men had suicidal thought or attempt more than twice as likely as women (7.69% vs. 2.35%). The probability of suicide in future was more in men than women (1.53% vs. 0). There was a strong and significant (P ≤0.00) correlation between questions of suicidal behavior questionnaire and psychological distress.
Conclusion: The higher scores of suicide and psychological distress of medical students in primary educational years, can reflect the high pressure volume, which they gain more compatibility, skill and ability for coping with the problems over time. By achieving the results of the current study, researchers would pay attention to psychological issues in healthcare workers, probable problems would be solved, and eventually, treatment of patients would done by more confidence
Communities. Classes. Races, Social pathology. Social and public welfare. Criminology
Fourth-Generation Multi-Theory Model (MTM) of Health Behavior Change as a Novel Strategy for Sustainable Health Promotion: A Systematic Review
Manoj Sharma, Asma Awan, Ana Gonzalez
et al.
Background: Health promotion has evolved significantly since its conceptualization, emphasizing the need for sustainable interventions to address population health challenges. This systematic review explored the effectiveness of the multi-theory model (MTM) of health behavior change in promoting sustainable health behavior.
Methods: Following PRISMA guidelines, a comprehensive search was conducted across MEDLINE, CINAHL, APA PsycINFO, and Academic Search Premier databases. From 883 records sourced after removal of duplicates, abstracts were screened and followed by complete article reading and screening. Eight experimental studies (four randomized controlled trials and four quasi-experimental studies) published between 2016 and 2024 were included. Data extraction focused on study design, population, interventions, and outcomes, with risk of bias assessed using Cochrane tools (RoB 2 and ROBINS-I).
Results: The findings revealed significant improvements in health behaviors, including reduced water pipe smoking, increased physical activity, healthier diets, and enhanced quality of life. MTM constructs—particularly participatory dialogue, behavioral confidence, emotional transformation, and practice for change—showed strong, statistically significant effects (p < 0.001). Process evaluations confirmed high intervention fidelity, strong engagement, and feasibility for community implementation. Despite small sample sizes, biases, and heterogeneous designs, the interventions effectively promoted sustainable, equitable behavior change across diverse populations. Overall, the results demonstrate the MTM’s potential for long-term health promotion through integrated behavioral and environmental strategies that align with public health sustainability goals.
Conclusion The review underscores MTM's potential as a robust framework for sustainable health promotion. By integrating environmental sustainability principles and fostering community engagement, MTM-based interventions can address social determinants of health and promote long-term behavior change. Future research should focus on scaling MTM interventions, addressing methodological limitations, and exploring its integration with other sustainability frameworks to enhance public health outcomes.
Communities. Classes. Races, Social pathology. Social and public welfare. Criminology
New Approach Methodologies: Physiological responses of daphnids to pharmaceutical mixtures
Emma Rowan, Anne Leung, Katie O’Rourke
et al.
Conventional methods for water monitoring are insufficient to capture the impacts of pollution because of their sensitivity limits, while they also fail to provide mechanistic insight regarding the actions of pollutants. On the other hand, New Approach Methodologies are more and more introduced as supplementary tools that provide sensitive metrics for pollution assessment. In this context, freshwater sentinel species commonly known as water fleas were used to assess the impact of a pharmaceutical mixture. The pharmaceutical cocktail comprised of representatives of commonly encountered pharmaceuticals and specifically diclofenac, metformin, gabapentin, amoxicillin, trimethoprim, and erythromycin. Combining toxicity, phenotypic and molecular endpoints, results showed differences in mortality, feeding, key enzyme activities and metabolic perturbations, thus supporting a distinct pattern in physiological responses of daphnids that could be used to monitor and predict pollution early.
Hazardous substances and their disposal
Композиционные материалы на основе полипропилена и наночастиц CoFe2O4, полученные методом полимеризационного наполнения
Жуков, А.М., Семенов, А.В., Клямкина, А.Н.
et al.
Методом полимеризационного наполнения синтезированы композиционные материалы на основе полипропилена и наноразмерного феррита кобальта (CoFe2O4). Исходные наночастицы охарактеризованы методами просвечивающей электронной микроскопии (ПЭМ), средний размер наночастиц составил около 7,5 нм. Композиты также охарактеризовали методом ПЭМ, согласно которому установлено, что частицы в материале распределены равномерно, при этом часть из них агломерирует. Методами дифференциальной сканирующей калориметрии и термогравиметрического анализа были исследованы теплофизические свойства композитов. Полученные данные свидетельствуют об увеличении термостабильности полипропилена в присутствии наноразмерного CoFe2O4. Также были исследованы магнитные свойства исходного феррита и композитов на его основе. Все полученные образцы можно отнести к классу магнитомягких. Значение намагниченности насыщения (Ms) увеличивается с повышением концентрации феррита кобальта в полипропилене.
Hazardous substances and their disposal
Substantially underestimated PFAS pollution in diverse Ghana’s land-use types revealed by a refined TOP assay
Liang Zhao, Junjie Zhang, Shivani Kubendraraj
et al.
Per- and polyfluoroalkyl substances (PFAS) research in developing countries has largely focused on imported sources such as e-waste, but contributions from local land-use activities remain poorly understood. This study selected Ghana as a model to investigate PFAS contamination in sediments from riverine ecosystems across four land-use types: mining, municipal & electronic waste, and agriculture. In addition to conventional target analysis, we refined the direct total oxidizable precursor (dTOP) assay by applying direct oxidation to sediments, with the highest PFAS yields achieved using an eightfold increase in oxidizing agents. Target PFAS concentrations were relatively low, likely reflecting the impact of global regulations, but post-dTOP concentrations increased by 239–65,400 % across all sites, ranging from 0.603 to 476 ng/g. Over 99 % of detected PFAS were attributed to previously untargeted precursors, emphasizing the iceberg nature of PFAS contamination, where routine methods capture only a small visible fraction. Mining and agricultural areas showed higher PFAS levels than the e-waste zone, suggesting that locally driven sources are dominant contributors. The tailored dTOP approach proved essential in revealing these hidden PFAS burdens, highlighting the need for broader monitoring frameworks to inform environmental risk assessment and sustainable land-use management in developing regions.
Hazardous substances and their disposal
Significant production of alkyl halides from (aliphatic) carboxylic acids in the UV/chlorine process
Xueling Bai, Xiaoqing Li, Baoqiang Hao
et al.
Ultraviolet radiation combined with free chlorine (UV/chlorine) is an attractive alternative to UV or chlorination alone for disinfection. However, •OH and Cl• radicals from UV/chlorine have recently raised increasing concerns about the possible formation of chlorinated products. A significant quantity of alkyl halides was generated from aliphatic carboxylic acids in the UV/chlorine process, in contrast to the absence of any detectable alkyl halides during chlorination alone. During the UV/chlorine process, the formation of CH3Cl, CH3CH2Cl and CH3CH2CH2Cl were was observed from acetic acid, propionic acid and n-butyric acid, respectively. The maximum yield of CH3Cl was up to 54.6 % when acetic acid was treated at a chlorine to precursors (Cl/P) ratio of 4.0. In addition to CH3Cl, CH2Cl2 and CHCl3 were also detected as the products of acetic acid. The presence of bromide ions resulted in a reduction in the yields of chloroalkanes, the formation of bromine byproducts, and an increase in the total amount of halocarbons. Hydroxyl radicals and chlorine radicals were identified as key reactants in the radical quenching experiments. The reactions described in this paper contribute to the understanding of the mechanism of halogenated byproduct formation during the UV/chlorine process. Synopsis: The radicals resulting from UV/chlorine lead to the conversion of carboxylic acids into a significant amount of alkyl halides that would not be generated by chlorination alone.
Hazardous substances and their disposal
Characteristics and risk assessment of microplastic mediated heavy metal transport in black clam Villorita cyprinoides from a Ramsar wetland of South India
Prachi Siddharth Bagde, Rini Mathew, Roshna Jose
et al.
The synergetic and interactive effects of microplastics (MPs) as potential carriers of pollutants and pathogens have a manifold impact on human health and aquatic biota. The present study delineates the role of MPs in transporting heavy metals to the black clam, Villorita cyrpinoides of Vembanad Lake in South India. MPs in water (3.41 ± 1.87 items/L), sediment (154.6 ± 45.4 items/kg) and within clams (0.87 ± 0.34 items/g tissue) showed considerable variation based on their physical and chemical characteristics, which in turn reflected its differential potential to carry heavy metals. Though the levels of heavy metals (Al, Fe, Mn, Zn, Cr, Pb) within the clam and those carried by MPs were less than the hazardous limits, the concentration of Cd within the clam and MP was found to have a positive correlation. Though the present levels of heavy metal pollution in the lake do not pose a direct threat to humans, anthropogenic interventions and reduced water flow have turned the lower reaches of the lake into a sink of heavy metals. Hence with MP concentration increasing it is worth investigating how their future interactions with heavy metals and other pollutants would pose a risk to living organisms.
Hazardous substances and their disposal
Feasibility Study on Providing Bibliotherapy Services in Addiction Treatment Camps Affiliated with State Welfare Organization (SWO) in Tehran Province
Leila Nemati-Anaraki, Nasibeh Shahkhah, Masoud Roudbari
et al.
Background: The purpose of this study is to evaluate the feasibility of providing bibliotherapy services in addiction treatment camps affiliated with State Welfare Organization (SWO) in Tehran province. The research concerns information resources and manpower, financial resources and technical infrastructure as well as expressing the shortcomings and barriers of this method.
Methods: The present study was conducted through a descriptive-survey method with an applied purpose in 2020. A questionnaire was developed by the researcher and validated with the help of experts. In order to assess the reliability of the questions, Cronbach's alpha test was used, which was calculated at 0.925. Sampling was performed using Cochran's formula. The sample size included 66 officials in 66 addiction treatment camps. SPSS software version 22 was used for data analysis
Results: The possibility of providing bibliotherapy services in terms of specialized and committed manpower in the field of bibliotherapy in addiction treatment camps was desirable. These centers were not in a good financial position. There was also the possibility of providing bibliotherapy services in terms of the technical infrastructure and manpower. The most effective methods of implementing bibliotherapy in addiction treatment camps were creative and group methods. Lack of budget and trained staff, staff reluctance to provide bibliotherapy services and lack of support from SWO were obstacles which have hindered the provision of bibliotherapy services in addiction treatment camps in Tehran province.
Conclusion: The benefits of providing bibliotherapy services in addiction treatment camps include increasing the client's psychological well-being, improving physical condition, preventing the client from returning to drug use, and to some extent, reducing the time of quitting drugs. Assessing and eliminating the shortcomings and barriers of bibliotherapy can play effective roles in the implementation of bibliotherapy.
Communities. Classes. Races, Social pathology. Social and public welfare. Criminology
The Effect of Supportive Supervision on Improving the Health Indices of Health Centers in Khomeinishahr, Iran
Monika Motaghi, Mohamad Tavakoli, Shahab Shahabi
Background: This study investigated the effect of supportive supervision on improving the health activity index.
Methods: The present interventional study was conducted to investigate the control and headquarters level in the organization to increase and improve 8 health indicators. Ten experts from the headquarters stationed in Khomeini Shahr communicated with the personnel of 10 health centres. The population covered by health centres was 40,000 people. The health indicators of the centres were compared before and after 3 months of the supervisory intervention of staff experts from SIB system (Integrated health system). Paired t-test and Kolmogorov-Smirnov test were used to test the items and to check for normality of data distribution. SPSS19 was used for data analysis (P<0/001).
Results: The results showed that all indices except health care activity had a significant increase. Indicators were: child care activity from 71.5 to 83.6%, activity of pregnant mothers from 65.1 to 77.29%, medical care coverage from 149.5 to 187.6%, death rate reports from 10.9 to 20.4%, mental health care from 7.9 to 11.1%, post-natal care from 75.0 to 84.9%, and the percentage of the covered population from 66.2 to 80.6%. Only the health care activity index did not improve significantly and increased from the average of 180.6 to 200.3%. We saw the lowest growth of the index in health care, which increased from 180.6 to 200.3%
Conclusion: Considering the significant impact of the intervention on the indicators, it is predicted that supportive monitoring training will improve the health quality of the country's health system.
Communities. Classes. Races, Social pathology. Social and public welfare. Criminology
Effect of Disease Education on Knowledge and Attitude of Nursing Mothers towards Typhoid Prevention in Akinyele Local Government Area of Oyo State, Nigeria
S Aderemi Famuyiwa, F Moses Ogundokun, S Dusin Oloruntegbe
Background: Typhoid fever is a disease is most predominant with great mortality among children of under five years of age especially in low and middle income countries where poor sanitation and poor hygiene lead to transmission of the disease. This study is focused on determining the effects of disease education on knowledge and attitude towards typhoid prevention among nursing mothers in Akinyele Local Government area of Oyo state.
Methods: The research design for this study was pretest-protest control group, quasi-experimental research design using 2×2 factorial matrix. The study used factorial matrix design based on the fact that the study involved the use of independent variables at two levels; treatment and control. Moderating variable of educational background at two levels (none formal education and formal education), multistage sampling procedure was adopted to select participants of two hundred (200) registered nursing mothers as sample. A self-developed questionnaire was used for data collection with reliability value of 0.72. the inferential statistics of analysis of covariance (ANCOVA) to test the hypotheses at 0.05 alpha level.
Result: The result from the study revealed that there was significant main effect of treatment on knowledge and attitude of nursing mothers towards typhoid prevention among nursingnmothers in Akinyele Local Government, Oyo State with (F(1/170) = 12.82, p <.05, ɳ2 = 0.07). (F(1/170) = 271.99, p <.05, ɳ2= 0.62) respectively.
Conclusion: It was concluded that disease education was very effective and has positive influence in improving the knowledge and attitude of nursing mothers towards typhoid prevention in Akinyele Local Government Area of Oyo State., Recommendation was made that there is need for massive health education campaign to educate the nursing mothers and generality of the populace by governmental and non-governmental agencies to correct the wrong perception they have about malaria and typhoid fever for effective prevention, treatment and control of the diseases.
Communities. Classes. Races, Social pathology. Social and public welfare. Criminology
Hydrogen-polarized vacuum ultraviolet photolysis system for enhanced destruction of perfluoroalkyl substances
Gongde Chen, Sitao Liu, Qingyang Shi
et al.
Reductive water treatment using hydrated electrons (eaq−) is a promising technology to destruct perfluoroalkyl substances; however, it faces challenges of slow reaction kinetics, undesirable chemical addition, and high energy consumption. Herein, we developed a hydrogen (H2)-polarized water photolysis system using vacuum UV (VUV) light at 185 nm for reductive destruction of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS). The 185-nm photons directly photolyzed H2O and OH- into HO·, H·, and eaq−. H2 elevated the quasi steady-state concentration of eaq− 18 times in untuned VUV systems through eliminating the scavenging effect of dissolved oxygen and converting hydroxyl radicals (HO·/O·-) into eaq−. The polarization effect of H2 increased the degradation of PFOA from 10 % to 95 % and the defluorination from 17 % to 94 % and led to 87 % of defluorination for PFOS. The pH impacted VUV photon adsorption between H2O and OH- and shifted the equilibrium between H· and eaq−, which led to an optimal pH of 10.3 for PFOA destruction. The presence of chloride and sulfate enhanced the production of eaq− and promoted PFOA destruction. H2-polarized VUV water photolysis systems produced high levels of eaq− from clean water constituents and significantly reduced energy consumption for PFAS treatment under mild alkaline conditions.
Hazardous substances and their disposal
Predicting Home Violence, According to Perceived Social Support and Marital Satisfaction for Infertility Women in Tehran, Iran
Behzad Ghorbani, Mehdi Shahnazari, Seyede Sedighe Hosseindoust
et al.
Background: Studies in many regions of the world indicate that women bear the burden of infertility. Infertile couples are expected to be involved in various psychological and social problems. Social support may lessen the psychological pain of infertility in women. Also, violence and inequality against women are raised in such families. This research aims to survey domestic violence in women based on social support and marital satisfaction in infertile women in Tehran.
Methods: In this study in 2018, authorities randomly selected 130 infertile women for an interview in Avicenna infertility center in Tehran. After obtaining informed consent, participants completed a questionnaire. It included domestic violence against women, social support (MSPSS) and marital satisfaction (Enrich 47) questionnaires. Data and statistical analysis of the research hypotheses was performed using SPSS v22. Moreover, Kolmogorov-Smirnov test, Watson's camera statistics, Pearson correlation coefficient, multivariate correlation coefficient and simultaneous multivariate regression analysis were used. The significance level was considered less than 0.05 and the confidence interval (CI) was 95%.
Results: In this study, the mean age of women was 31.63 (47-23) and the mean duration of the marriage was 0.50 (2-20). Two variables of social support and marital satisfaction predicted the domestic violence against women to be 0.388 (38.8%). Marital satisfaction had a significant effect on domestic violence against infertile women (p=0.001). The higher the marital satisfaction (T= -8.997, p= 0.001), the less would be the domestic violence against infertile women.
Conclusion: Findings showed that in infertile women, domestic violence is predictable with perceived social support and marital satisfaction.
Communities. Classes. Races, Social pathology. Social and public welfare. Criminology
Toxic effects of Rhodamine B on antioxidant system and photosynthesis of Hydrilla verticillata
Jyotshana Sharma, Shubhangani Sharma, Upma Bhatt
et al.
Rhodamine B is a synthetic dye released in huge quantities as hazardous colored effluents into aquatic ecosystems. It negatively affects the metabolic and physiological processes in aquatic plants. The goal of current study was to assess the impact of various Rhodamine B concentrations (5, 10, 15, 20, and 25 mg/L) on antioxidant and photosynthetic performance of Hydrilla verticillata exposed for 24, 48, and 72 h. Results of present study clearly demonstrate that Rhodamine B inhibits the activity of the superoxide dismutase (SOD), catalase (CAT), and guaiacol peroxidase (GPOD) in H. verticillata. Activities of SOD, CAT, and GPOD were constantly raised at lower concentrations and then decreased with increasing concentration and exposure duration of Rhodamine B. In vivo chlorophyll fluorescence experiments were used to examine its inhibitory effects on H. verticillata photosystem II (PSII). The OJIP fluorescence induction kinetics were altered by increasing the Rhodamine B concentration and treatment time as a result increasing the parameters Fo/Fm and φDo while decreasing Fm, φPo, Ψo, φEo, RC/CSm, ABS/CSm, TR/CSm, ET/CSm and, PIabs. When exposed to Rhodamine B, electron transport is slowed down on both the acceptor and donor sides and overall decreases the photosynthetic performance of H. verticillata.
Hazardous substances and their disposal
Serious Suicide Attempt by Hunting Gun with Severely Infectious Wounds and Facial Deformity during COVID-19 Arena; A Case Report
Reza Bidaki, Maryam Sadeh
The etiology of suicide among students around the world revolves issues such as communication, education, family problems and parents’ relationship. We intend to report a case with serious recurrent suicide attempt by gun shot during COVID-19 period. We also present psychiatric and clinical evaluation, cosmetic surgery consultation, as well as microbial assessments in this survey.
The seventeen-year-old single male student from southwest of Iran with asymmetric deformed face was observed with the loss of parts of the mouse, nose, chin and mandible region .He had experienced a serious suicide attempt by a threatening plan following rejection. The patient had blurred, hypo phonic and hypotonic speech. Following the shooting, the soft and hard palate, facial, frontal bone and sinus had been destroyed and a foreign body was seen in the frontal sinus. After suicide risk as assessment, It was detected multiple predictive risk factors for recent suicide attempt and the possibility of recurrent suicide in future. Finally, reconstructive surgery was performed. We assessed him via face to face interview in order to identify psychiatric disorders. Also, he was evaluated as probability of committing recurrent suicide.
It is emphasized that in families which young children are prone to psychiatric disorders or emotional problems, availability of a dangerous device such as a gun can be harmful and it should be removed as soon as possible. We suggest the need for psychiatric evaluation especially suicide phenomenon in adolescents and their families as various conflicts in family context.
Communities. Classes. Races, Social pathology. Social and public welfare. Criminology
Frontier review on comprehensive two-dimensional gas chromatography for measuring organic aerosol
Zhaojin An, Xue Li, Zongbo Shi
et al.
Organic aerosol (OA) is a key component of atmospheric fine particles and can be composed of thousands of organic species, creating an analytical challenge to separate and identify such highly complex mixtures. Traditional offline one-dimensional gas chromatography, mostly separating molecules based on volatility, provides valuable information on the composition of OA, but is limited by insufficient separation and low peak capacity. Since its introduction in 1990s, comprehensive two-dimensional gas chromatography (GC × GC), which separates molecules by both volatility and polarity, has become an effective tool to determine the OA composition through its high molecular separation resolution and high peak capacity. Both online and offline GC × GC analyses have been applied to study OA, which extended the identification of unknown compounds and the quantification of a larger range of target compounds. Here, we review the studies using GC × GC for analyzing OA from both the ambient environment and source emissions. GC × GC coupled with mass spectrometry provides a variety of novel analysis methods, demonstrating the power of GC × GC analyzing complex aerosol samples. The development of online technologies in recent years helps to capture the dynamic temporal variations of atmospheric OA due to changes in source emissions as well as atmospheric secondary formation and meteorology.
Hazardous substances and their disposal
Total and class-specific analysis of per- and polyfluoroalkyl substances in environmental samples using nuclear magnetic resonance spectroscopy
Dino Camdzic, Rebecca A. Dickman, Diana S. Aga
This study reveals unique information that fluorine nuclear magnetic resonance (19F-NMR) spectroscopy provides in the analysis of per- and polyfluoroalkyl substances (PFASs). Our results demonstrate that the intensity of the terminal -CF3 signal can be used to determine the total PFASs regardless of headgroup. Characteristic chemical shifts of different classes of PFASs can also be observed, and are useful for differentiating between classes of PFAS. The NMR spectra of PFASs with ether linkages (e.g. GenX) show characteristic reference signals for both -CF2 and -CF3 signals that are useful for detection. Notably, 19F-NMR can differentiate between PFASs, non-PFAS, and F− ions, eliminating the need for sample clean-up even for complex samples. To illustrate this, the 19F-NMR spectra of perfluorooctane sulfonic acid (PFOS) in biosolids extract and in clean solvent spiked with PFOS standard were compared, and showed a difference of < 0.3 % in their signal intensities. The lack of matrix effect is contrary to the suppression or enhancement observed in PFAS analysis by liquid chromatography with mass spectrometry, the most commonly used method for quantifying PFASs. This paper presents 19F-NMR reference spectra for 34 PFASs and discusses the complementarity of this method with other approaches for the total and class-specific analysis of PFASs.
Hazardous substances and their disposal
The Effectiveness of Buckroyd’s Group-Based Therapeutic Approach on Increasing Efficiency Life Style and Improving Body Self-Image
Fariba Hosseini, Yousef Gorgi, Afsaneh Javadzadeh
Background: Group teaching can create empathy in teaching sessions. Therefore the objective of the present study was to investigate the effectiveness of team teaching based on Buckroyd’s Method on lifestyle, self-efficacy and body image structure of the women with obesity in the city of Isfahan.
Methods: This study was quasi-experimental with pretest, posttest and control group and follow-up. The statistical population of the study included all people with obesity referring to clinics in the city of Isfahan from whom 30 women with obesity were selected through purposive sampling from Sepahan Health clinic in 2014 and then they were put into two groups of fifteen (experimental and control). A therapeutic intervention based on Buckroyd Method was administered on the experimental group during 16 two-hour sessions twice a week. The measurement instruments in this study were BMI scale, demographic information form, life style self-efficacy questionnaire and body image questionnaire. Descriptive statistics (mean and standard deviation) and inferential statistics (repeated measures variance) were used to test the hypotheses using SPSS software (version 23) at 0.05 level of error.
Results: The results showed that team teaching based on Buckroyd Method has been effective on the increase of life style self-efficacy (p < 0.001) and the improvement of body image (p < 0.001) as the mean score of life style self-efficacy and body image structure have increased after team teaching at the post-test stage and it could maintain this increase in time (follow-up stage).
Conclusion: Buckroyd Method can be employed in the increase of life style self-efficacy and body image structure in the obese women.
Communities. Classes. Races, Social pathology. Social and public welfare. Criminology
Subacute episodic exposure to environmental levels of atmospheric particulate matter provokes subcellular disequilibrium instead of histological vascular damage
Yan Wang, Lilin Xiong, Lingyue Zou
et al.
Hazardous impacts of subacute exposure to atmospheric particulate matter (PM) on the vascular system are not fully understood. Much emphasis has been put on apparent pathological alterations previously, but early checkpoints were scarcely centralized in the course of cardiovascular disequilibria, such as the cellular or/and subcellular visions. In the current study, a tertiary assessment was implemented, including aortic tissues, vascular cells and subcellular equilibrium. As a result, subacute PM aspiration exerted negligible effects on lipids deposition of vascular walls. However, adverse effects were determined at the cellular and subcellular levels, such as endothelial monolayer disintegration and organelle dysfunction. Specifically, endoplasmic reticulum (ER) stress and mitochondrial malfunction were provoked by PM stimulus. Furthermore, correlation analysis suggested a strong association between aortic ox-inflammatory cascade and vascular subcellular disequilibrium. Altogether, subcellular, cellular and histological levels were assessed to gain a comprehensive understanding of vascular toxicity by realistic concentrations of PM, from which even in the absence of pathological changes, vascular endothelial cells and subcellular structures were predominantly damaged. In particulate toxicology, the necessity of early checkpoints needs to be further strengthened.
Hazardous substances and their disposal