Hasil untuk "United States"

J. Gaddum

The Pharmacopeia of the United States of AmericaFifteenth Revision. (U.S.P. 15.) Pp. lii + 1178. (New York: United States Pharmacopeial Convention, Inc., 1955. Distributed by Mack Publishing Company, Easton, Pa.) 10 dollars.

A. W. Küchler

R. Gallman, J. Kendrick

H. Zinn

S. Reichard, P. White

J. A. Grunbaum, L. Kann, S. Kinchen et al.

B. Ark, M. O’Mahony, M. Timmer

R. Yabroff, K. Yabroff, E. Lamont et al.

J. Moorman, Rose Anne Rudd, Carol A Johnson et al.

P. Sebel, T. Bowdle, Mohamed M. Ghoneim et al.

M. Whiteman, S. Hillis, D. Jamieson et al.

W. Callaghan, Elena V Kuklina, C. Berg

C. Bern, S. Montgomery

A. P. Williams, C. Allen, C. Millar et al.

M. Iwamoto, T. Ayers, B. Mahon et al.

H. Wunsch, W. Linde‐Zwirble, D. Angus et al.

S.B. Jelsma, M. Zijlmans, I.B. Heijink et al.

Epilepsy surgery is usually based on the removal of a local epileptogenic zone. If epilepsy is considered a network disease, a network approach might be more suitable. Insight into patient-specific epileptic brain networks is necessary to establish network-based surgical strategies.We included epilepsy surgery candidates who underwent diffusion-weighted imaging and intracranial EEG implantation with single pulse electrical stimulation (SPES, 0.2 Hz, 1–8 mA, 1 ms, monophasic stimuli) during presurgical evaluation. We reconstructed structural connectivity using fiber tractography taking intracranial electrodes as nodes. We reconstructed effective connectivity with SPES cortico-cortical evoked responses. We determined the inter-modal similarity between structural and effective connectivity with the Jaccard index, and compared network topologies using degree and betweenness centrality. We constructed a linear multilevel model to evaluate the relation between structural and effective connectivity at subject group level. The seizure onset zone nodes (SOZ), node proximity, and the volume of the electrode contact areas (VEA) were added to the model as possible predictors to accommodate for epilepsy and irregular spatial sampling.We included 13 patients (five with electrocorticography, eight with stereo-EEG). The median Jaccard index was 0.25 (IQR: 0.20–0.29), which means there is a higher overlap than expected by chance (median expected Jaccard index = 0.1 (IQR: 0.07–0.17)) with a considerable amount of connections that did not overlap. The structural connectivity degree showed a significant positive correlation with the effective connectivity degree in 9/13 patients and at group level after accommodating for node proximity (β = 0.13, 95 %-CI = [0.04, 0.21], t(852) = 2.79, p = 0.0054). SOZ and VEA were no significant predictors for the correlation between structural and effective connectivity.We showed a moderate overlap between non-invasive structural (measured with DWI) and invasive effective (measured with SPES) connectivity in epileptic brain networks. This overlap supports using non-invasively determined connectivity along with intracranial EEG to understand the epileptic brain. Future research needs to translate these findings towards network-based surgical strategies.

Sally Jordan, Sarah Bakewell, Holly Jane Campbell et al.

Across the United Kingdom, initiatives designed to increase the participation and outcomes for women in physics continue, working with children of various ages as well as with adults. Improvements have been achieved by a combination of these initiatives and an accompanying strengthening of policy, but significant gender imbalances remain.

Francisco Agostinho, Simão Correia, Hugo Tavares

We study the orbital stability of action ground-states of the nonlinear Schrödinger equation over two particular cases of metric graphs, the $\mathcal{T}$ and the tadpole graphs. We show the existence of stability transitions near the $L^2$-critical exponent, a new dynamical feature of the nonlinear Schrödinger equation. More precisely, as the frequency $λ$ increases, the action ground-state transitions from stable to unstable and then back to stable (or vice-versa). This result is complemented with the stability analysis of ground-states in the asymptotic cases of low/high frequency and weak/strong nonlinear interaction. Finally, we present a numerical simulation of the stability of action ground-states depending on the nonlinearity and the frequency parameter, which validates the aforementioned theoretical results.