Hasil untuk "Nursing"

Mohammed Nasser Albarqi, Mohammed Yousef Almulhim, Mai Adel Albana

Abstract Background Listening beyond words is central to culturally safe nursing care, particularly in rural hospital settings where communication with Bedouin patients is shaped by dialect, silence, gesture, and deeply embedded social and spiritual meanings. In rural Saudi hospitals, however, nurse–patient interactions are often conducted in standardized Arabic and organized around biomedical routines, creating cultural–linguistic gaps that may undermine trust, engagement, and perceived safety in care. Aim To explore how cultural safety is experienced, threatened, and co-constructed through spoken and unspoken language between Bedouin patients and nurses in rural hospitals in Al-Ahsa, Saudi Arabia, and to identify nurse-led strategies that make care feel culturally congruent. Methods An interpretive phenomenological design informed by critical cultural safety was used. Semi-structured interviews were conducted in Arabic with 20 participants (10 Bedouin patients and 10 registered nurses) from two rural hospitals in Al-Ahsa. Interviews were audio-recorded, transcribed verbatim, selectively translated for publication purposes, and analyzed using Braun and Clarke’s six-phase thematic analysis supported by NVivo. Results Four interrelated themes described the cultural–linguistic work of care: (1) Speaking without words—patients used silence, indirectness, and kin-based framing that nurses had to learn to “listen for”; (2) Clinical space as cultural distance—hospital rules, gendered assignments, and rapid tasking were experienced as unfamiliar and sometimes unsafe; (3) Trust is earned, not assumed—historic and institutional marginality meant nurses had to demonstrate respect through repeated relational encounters; and (4) Navigating toward connection—nurses used local dialects, religious invocations, and family mediators to repair distance and legitimise communication. Conclusions Cultural safety for Bedouin patients cannot be achieved through translation alone. It requires relational listening, time, and organizational permission to use culturally grounded communication. Rural services should embed dialectal and cultural resources, support gender-sensitive assignments, and normalize family-inclusive encounters. Nursing education and continuing professional development should strengthen linguistic humility. Clinical trial number Not applicable.

Alyce S. Ashcraft, Donna C. Owen, Kyle Johnson et al.

Urinary tract infections (UTIs) occurring in nursing home (NH) residents are poorly assessed and challenging to treat. The emergence of clinical decision support (CDS) technology provides an opportunity for improved diagnosis and treatment of UTIs in the NH. The purpose of this study was to report findings examining the feasibility of licensed vocational nurses (LVNs) using a CDS algorithm designed to directly guide assessment of a standardized NH resident experiencing symptoms of a potential UTI in a simulation setting at a university in the Southern United States. A structured observational design was used. A sample of ten practicing nurses used an algorithm developed by the authors from published UTI assessment and practice-driven criteria. Data collection was framed using (a) UTI-guided assessment tool, (b) analysis of LVN behavior and verbal interaction with the algorithm, and (c) postsimulation interviews about the algorithm and nurse–resident interactions. Results showed LVNs found the algorithm easy or very easy to use, their behaviors demonstrated high levels of engagement with the simulation while using the algorithm, and interviews supported the positive value LVNs placed on using an algorithmic approach for UTI assessment. The algorithm we developed fills a gap in the current approaches to diagnosing a UTI in the NH by focusing on the role of the LVN in data collection in relation to assessment of the resident.

Lilach Ben Shabat, Michal Itzhaki

Abstract Background Choosing a field of specialization within the nursing profession is affected by nurses’ personality traits, self-confidence in performing clinical skills, and the field’s prestige. A successful choice of area of expertise may improve nurses’ job satisfaction and reduce job mobility. This study aims to examine the relationship between personality traits, clinical self-efficacy, perceived prestige, adoption of technological changes, and choice of specialty field among nursing students. Methods A cross-sectional study was conducted. One-hundred-twenty-seven undergraduate nursing students in their fourth year of studies at a large university in Israel participated in the study. The questionnaire administered was comprised of six parts: demographic data, personality traits, adoption of technological changes, clinical self-efficacy, perceived prestige, and intention to select a field of specialization. Results Acute disciplines were rated more prestigious than chronic disciplines, with intensive care and emergency medicine considered the most prestigious, while mental health and geriatrics were the least prestigious. Students’ mean perceived confidence in performing nursing clinical skills was high and more than half considered themselves open to technology changes. Positive correlations were found between prestige and intention to choose a field of expertise (r = 0.41, p < 0.001) and the personality trait of openness and the intention to choose an acute care area (r = 0.26, p < 0.01). Conclusions Despite the gradual aging of the population and the increase in chronic morbidity, which demand a greater nursing focus on older adults, and notwithstanding the mental health reforms, nursing students perceive geriatrics and mental health as less prestigious fields. A career development path can be applied by developing a tool for occupational guidance designed to rank students’ suitability for specialty fields and thus help them choose the area that best suits them.

Ling Wang, Zhihan Gu, Xiaoli Chen et al.

Abstract Objective To investigate risk factors associated with long-term mortality in patients with stage II and III tuberculous meningitis (TBM). Methods This retrospective analysis examined patients who were first diagnosed with stage II and III TBM at West China Hospital of Sichuan University between January 1, 2018 and October 1, 2019. Patients were followed via telephone and categorized into survival and mortality groups based on 4-year outcomes. Multivariate logistic regression identified independent risk factors for long-term mortality in stage II and III TBM. Results In total, 178 patients were included, comprising 108 (60.7%) males and 36 (20.2%) non-survivors. Mean age was 36 ± 17 years. Compared to survivors, non-survivors demonstrated significantly higher age, heart rate, diastolic blood pressure, blood glucose, rates of headache, neurological deficits, cognitive dysfunction, impaired consciousness, hydrocephalus, and basal meningeal inflammation. This group also exhibited significantly lower Glasgow Coma Scale (GCS) scores, blood potassium, albumin, and cerebrospinal fluid chloride. Multivariate analysis revealed age (OR 1.042; 95% CI 1.015–1.070; P = 0.002), GCS score (OR 0.693; 95% CI 0.589–0.814; P < 0.001), neurological deficits (OR 5.204; 95% CI 2.056–13.174; P < 0.001), and hydrocephalus (OR 2.680; 95% CI 1.081–6.643; P = 0.033) as independent mortality risk factors. The ROC curve area under age was 0.613 (95% CI 0.506–0.720; P = 0.036) and 0.721 (95% CI 0.615–0.826; P < 0.001) under GCS score. Conclusion Advanced age, reduced GCS scores, neurological deficits, and hydrocephalus were identified as independent risk factors for mortality in stage II and III TBM patients.

Tang J, Klunklin P, Lirtmunlikaporn S et al.

Jian Tang,1 Pimpaporn Klunklin,2 Sumalee Lirtmunlikaporn,2 Yanan Wang3 1Department of Infectious Diseases, The Affiliated Hospital, Southwest Medical University, Luzhou, People’s Republic of China; 2Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand; 3School of Medicine and Health Care, Jiangyang City Construction College, Luzhou, People’s Republic of ChinaCorrespondence: Jian Tang, Email tangjian034@swmu.edu.cnPurpose: To clarify the meaning of treatment adherence and identify its attributes, antecedents, consequences, and empirical referents.Design: A concept analysis.Methods: Walker and Avant’s method was used to analyze treatment adherence. PubMed, Web of Science, Wiley Online Library, and EBSCO databases were searched from 2013 to 2023. The PRISMA 2020 checklist was used.Results: Seventeen studies were included in this analysis. The defining attributes were the ability to comply with the treatment, consistency in the treatment plan, communication with the healthcare provider, and willingness to treat. Antecedents included multiple medicines, lifestyle changes, illness perceptions and beliefs, and long-term treatment. The outcomes included treatment success, improved long-term treatment, and improved clinical outcomes.Conclusion: Treatment adherence is a positive reaction of a patient to have the ability to comply with the treatment, consistency in the treatment plan, communication with the healthcare provider, and willingness to treat. This study proposes a detailed definition, attributes, antecedents, consequences, and empirical referents for treatment adherence. It is instructive to clinical nursing of treatment adherence, can be extended to various diseases, helps to improve clinical nursing practice regarding treatment adherence, and contribute to improving human health.Keywords: treatment adherence, concept analysis, clinical nursing, nursing practice

Karla Andrea Canul Navarrete, Lidia Karina Pérez Aban, Aracely Yazmin Cab Cob et al.

Introducción: Las técnicas y materiales empleados para la alimentación enteral se han desarrollado, lo que ha permitido reducir las complicaciones, así mismo intervienen factores como las características de la dieta a administrar y el acceso al tracto digestivo. Metodología: Revisión sistemática, se identificaron términos y se tradujo a través del DeCS y MeSH, las fuentes documentales consultadas fueron: PubMed, Cochrane Library, Springer Link y Google académico,  como estrategia de búsqueda se crearon cadenas utilizando el operador booleano AND y términos libres en  el rango de tiempo  de 2012 a 2022, se consideraron artículos con diseños de revisiones sistemáticas, metaanálisis y ensayos clínicos aleatorizados que comparaban la nutrición gástrica versus pospilórica. Resultados: Se localizaron 839 artículos, se aplicaron criterios de elegibilidad seleccionando 13. Los estudios que cumplieron con los criterios fueron 9 artículos, con diseño de metaanálisis y revisiones sistemáticas.  Se evaluó la calidad de las evidencias mediante el instrumento Fichas de Lectura Crítica (FLC) en su versión 3.0 y para la asignación del nivel de evidencia, grado de recomendación la escala Centre for Evidence-Based Medicine, Oxford (OCEBM). Discusión: La nutrición pospilorica demostró una menor tasa de reflujo del contenido gástrico y menor incidencia de complicaciones gastrointestinales, mejora los resultados en los pacientes críticos por lo que disminuye la estancia en las unidades de cuidados intensivos Conclusiones: De acuerdo con los hallazgos obtenidos se encontró que la vía enteral pospilórica puede reducir el riesgo de aspiración pulmonar, sin embargo, es menos utilizada debido a la complejidad en la instalación.

Claudia Camedda, Gloria Bici, Camilla Elena Magi et al.

Chronic kidney disease affects many people around the world, leading those affected to replacement therapy such as hemodialysis. People who undergo hemodialysis generally undertake 2–3 treatments per week, lasting about 3–4 h each; patients spend many hours per week in contact with nurses, building a therapeutic relationship. The purpose of this work is to assess the quality of nurses’ perceived caring attitudes and behaviors and to determine their perceptions regarding the importance of the therapeutic relationship with the assisted patients. A self-reported questionnaire composed of three sections was administered to nurses; the first section included sociodemographic questions, the second the Caring Nurse–Patient Interaction Scale (CNPI-23), and the third part of the questionnaire was composed of open-ended questions investigating patients’ expectations according to nurses, the relevance of the therapeutic relationship on their work, and its effect on themselves and/or their own job satisfaction. Statistically significant correlations and trends have been observed between nurses’ sociodemographic data and the CNPI-23 items. In the clinical care area, nurses who have a post-basic degree or more years of experience feel more competent than those in other categories; in the relational care area, women tend to feel more competent than men. No correlations were found between the humanistic and comfort care areas. According to the results, the post-basic training of dialysis nurses and the adoption of organizational strategies that encourage nurse retention should be enhanced. This study was not registered.

* Global Health Organization Leadership, * Regional Leaders in Health

Dear COP 28 President-Designate Sultan Ahmed Al-Jaber, This year, world leaders gathering in the UAE to take stock of their climate commitments will for the first time engage in official programming focused on health. We, the signatories of this letter, support your leadership in bringing health front and center at COP28. As global health leaders, we are committed to achieving health and well-being for all; this is not possible without a safe and stable climate. The Paris Agreement enshrined the “right to health” as a core obligation for climate action. Yet, communities, health workers, and health systems around the world already face the alarming impacts of a changing climate. Climate change-induced extreme weather events are becoming more frequent and severe; many countries are grappling with the health consequences of extreme heat, unprecedented storms, floods, food and water insecurity, wildfires, and displacement. For COP28 to truly be a “health COP,” it must address the root cause of the climate crisis: the continued extraction and use of fossil fuels, including coal, oil, and gas. We call on the COP28 Presidency and the leaders of all countries to commit to an accelerated, just, and equitable phase-out of fossil fuels as the decisive path to health for all. Ending our dangerous dependency on fossil fuels will improve the health prospects of future generations and will save lives. Keeping the global temperature increase within the 1.5°C target of the Paris Agreement is essential to ensure good health and economic prosperity for all. This will only be possible if we rapidly phase out fossil fuels. Fossil fuel phase-out will limit global warming, thereby protecting health from the devastating impacts of extreme weather, and preventing further ecological degradation and biodiversity loss. Failing to do so will lead to overwhelming health consequences, as well as the loss of key natural resources and ecosystem services that are critical to both human and non-human species health, 1 there by undermining One Health and planetary health. In addition to climate-related health impacts, air pollution caused in part by burning fossil fuels causes 7 million premature deaths annually. 2 The economic costs 3 of air pollution-related health impacts amounted to over US$8.1 trillion, or 6.1% of global GDP, in 2019. By improving air quality, governments can reduce the burden of disease from multiple cancers, heart disease, neurological conditions including stroke, and chronic and acute respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD). Investments in clean energy sources will save hundreds of billions of dollars in health care costs associated with air pollution every year, while reducing economic losses from extreme weather events with damages worth US$253 billion (in 2021). 4 A full and rapid phase-out of fossil fuels is the most significant way to provide the clean air, water, and environment that are foundational to good health. We cannot rely on unreliable and inadequate solutions, like Carbon Capture and Storage (CCS), which extend the use of fossil fuels but do not generate the real and immediate health improvements which a renewable energy transition provides. False solutions like CCS risk making harmful emissions worse, straining the health of overburdened communities, and delaying our progress toward meaningful climate progress. The energy transition must be just and equitable for all. In transitioning to a clean energy future, there is an opportunity to undo the injustices of the fossil fuel-dependent system, taking a systemic approach and emphasizing health, care and community well-being, leaving no one behind. Global leaders must ensure everyone, including fragile states and the most remote and excluded communities, has access to non-polluting, affordable, reliable, accessible, and resilient clean energy, as well as to emerging technologies that make the best use of this energy. A just transition offers the opportunity to reduce health inequities faced by minority and marginalized communities, especially with respect to the health effects of ongoing fossil fuel use and dependence.  Unlocking finance is essential to deliver a healthy and just transition. Achieving climate and health goals will only be feasible if we stop investing in fossil fuels and invest instead in proven climate and health solutions. Each year, countries spend hundreds of billions of dollars subsidizing the fossil fuel industry, money that could be spent investing in a healthy future. High-income countries, development finance institutions, and the private sector must dramatically increase and fulfill their commitments to drive investments in clean energy, clean air, and economic development for the communities most harmed by climate change and fossil fuel pollution. Fossil fuel interests have no place at climate negotiations. The fossil fuel industry cannot be allowed to continue its decades-long campaign of obstructing climate action at the UNFCCC negotiations and beyond. Just as the tobacco industry is not allowed to participate in the WHO Framework Convention on Tobacco Control, it is imperative to safeguard global collaboration on climate progress from the lobbying, disinformation, and delays in favor of industry interests. Without ambitious climate action, the burden on health care systems and health care workers will be insurmountable. Health gains made in recent decades will be in vain and we will see the harmful impacts of climate change ruin our chances for a safe, equitable and just future.  In this extraordinary year, with health for the first time on the COP agenda, we urge you to deliver real climate progress: commit to an accelerated, just, and equitable phase-out of fossil fuels and invest in a renewable energy transition as the decisive path to health for all.  Sincerely, Global Health Organization Leadership (Alphabetical by organization) • Githinji Gitahi, CEO, Amref Health Africa • Pam Cipriano, President, International Council of Nurses • Salman Khan, Liaison Officer for Public Health Issues, International Federation of Medical Students' Associations • Naveen Thacker, President, International Pediatric Association • Dr Christos Christou, International President, Médecins Sans Frontières • María del Carmen Calle Dávila, Executive Secretary, Organismo Andino du Salud (Andean Health Organization) • Luis Eugenio de Souza, President, World Federation for Public Health Associations • Lujain Alqodmani, President, World Medical Association Regional Leaders in Health (Alphabetical by surname) • Mary T. Bassett, Director, FXB Center for Health and Human Rights, Harvard University • Fiona Godlee, Former Editor-in-chief of the British Medical Journal • (Dr.) Arvind Kumar, Chairman, Institute of Chest Surgery, Chest Onco Surgery and Lung Transplantation, Medanta Hospital, India • Dame Parveen Kumar, Emeritus Professor of Medicine and Education, Barts and The London School of Medicine and Dentistry • Lwando Maki, Secretary, Public Health Association of South Africa • Jemilah Mahmood, Executive Director, Sunway Center for Planetary Health - Malaysia • Kari C. Nadeau, MD, PhD, Chair of the Department of Environmental Health at Harvard School of Public Health • (Dr.) K Srinath Reddy, Past President of Public Health Foundation of India This letter is supported and endorsed by: National Health Organization Leadership (Alphabetical by organization) • Rosana Teresa Onocko Campos, President, Associação Brasileira de Saúde Coletiva (Brazil) • Katie Huffling, DNP, Executive Director, Alliance of Nurses for Healthy Environments (US) • Dr Latifa Patel, Representative Body Chair, British Medical Association • Kamran Abassi, Editor-in-Chief, British Medical Journal (UK) • Frances Peart, President & Board Chair, Climate and Health Alliance (Australia) • Kate Wylie, Executive Director, Doctors for the Environment Australia • Agonafer Tekalenge, President, Ethiopian Public Health Association • Diederik Aarendonk, Forum Coordinator Global Health Organization Leadership, European Forum for Primary Care • Kevin Fenton, President, Faculty of Public Health (UK) • Ansgar Gerhardus, Board Chair, German Public Health Association • Vital Ribeiro, Chair, Associação Civil Projeto Hospitais Saudáveis (Healthy Hospitals Project) • Sheila Sobrany, President, Royal College of Nursing • The Board of the Public Health Association of South Africa • Diana Zeballos, Executive Secretary, Sustainable Health Equity Movement (SHEM) • Adeline Kimambo, Executive Secretary, Tanzania Public Health Association • Richard Smith, Chair, UK Health Alliance on Climate Change

Meng-Yi Chen, Meng-Yi Chen, Qinge Zhang et al.

BackgroundA growing number of studies has implicated oxidative stress in the pathophysiology of psychiatric disorders including schizophrenia. The aim of this study was to explore the field of schizophrenia and oxidative stress-related research from a bibliometric perspective.MethodsAll relevant publications on schizophrenia and oxidative stress were obtained from Web of Science Core Collection (WOSCC) database from its inception date to November 8, 2022. VOSviewer software was used to examine co-authorships and co-occurring keywords. R software was used to present the main characteristics of publications and cooperation frequency among countries. CiteSpace was used to investigate keywords with the strongest citation bursts.ResultsA total of 3,510 publications on schizophrenia and oxidative stress were included. The United States had the largest number of publications (26.1%), and international collaborations. University of Melbourne was the most productive institution, while Schizophrenia Research was the most productive journal in this field. Apart from “schizophrenia” and “oxidative stress”, the terms “prefrontal cortex”, “brain” and “nitric oxide” were among the most frequently used keywords.ConclusionsIn conclusion, research on the association between oxidative stress and schizophrenia has received growing attention in the academic literature that is expected to continue its upward trajectory during the next two decades. Existing research suggests there has been a transition from research focused on pathways to animal models, and subsequently to clinical applications. Intervention studies on oxidative stress and schizophrenia are likely to be an important focus of related work in the near future.

Indri Paradillah, Evi Martha, Farandi Agesti Ramadhan et al.

Background: Infant mortality is one of the sensitive indicators to know the degree of health of a country and even to measure the level of progress of a nation. The Low Birth Weight Babies (LBW) are the highest cause of infant mortality in Depok until it reaches 81 cases in 2019. One of the efforts made by public health office to reduce the infant mortality rate is to use Kangaroo Mother Care. This research aims to analyze the implementation of Kangaroo Mother Care Program in public health center in Depok, Indonesia.  Methods: The method of study is qualitative with purposive sampling approach. Result: The results showed that the informants were not aware of the existence of Mayor Regulation Number 89 year 2020 regarding Kangaroo Method Care. Health workers do not yet have sufficient knowledge about the implementation of the Kangaroo Method of Care. The implementation of the Kangaroo Method of Care is still not supported by complete facilities. Human Resources is also still inadequate. Conclusion: The conclusion of this research is the Kangaroo Method Care program has not run optimally. There needs to be an effort to improve the implementation of the Kangaroo Method Care program at the public health center.

Magdalena Choina, Kinga Pożarowska, Gracjan Rudziński et al.

Introduction: Celiac disease (CD) is an autoimmune disease that affects genetically predisposed individuals. In course of the disease, consumption of gluten causes damage to the small intestine. Due to various clinical manifestations, diagnosing CD poses a challenge to clinicians. It has been proven by several study groups that the diagnostic delay in CD is still too long and provokes severe health complications.  Purpose: The aim of the study is to highlight the importance of diagnostic delay in CD, its consequences and possible solutions.  Description of the state of knowledge: The diagnosis of CD is based on the clinical picture, serological test, duodenal mucosal biopsies and genetic tests. Many cases of CD remain undiagnosed in spite of published guidelines for CD diagnosis. Consequently, the diagnosis is significantly delayed: the mean duration of the diagnostic process in Poland was 7.3 years. In other countries, patients the time from the onset of the symptoms to establishing CD diagnosis was up to 10 years. The diagnostic delay leads to reduced quality of life and the development of severe complications, such as neoplastic disease.  Summary: Diagnostic delay in CD is an issue of great importance. Because of the reduced quality of life and the possibility of neoplasm, it is crucial to take action in order to shorten the diagnostic process of CD.

Mathias Anthony Mbinda, Fabiola Vincent Moshi

Objective: The objective of this study was to identify factors associated with nurses’ and midwives’ skills in performing neonatal resuscitation. Method: Health facility-based analytical cross-sectional study design was employed from January 2021 to April 2021 among 340 nurses and midwives selected by multistage random sampling technique. An observation checklist was used to collect data. Data were coded and entered into SPSS version 20 for analysis. Bivariate and multivariate logistic regression was used to assess factors associated with nurse/midwives’ skills in neonatal resuscitation. Results: Among 340 nurses and midwives, 141 (41%) had adequate skills in neonatal resuscitation. After adjusting for confounders, factors associated with adequate skills were; age of the midwives (20–34 (adjusted odds ratio = 0.082, p  < 0.008) and 35–49 (adjusted odds ratio = 0.087, p  < 0.010)); work experience (worked 4–6 (adjusted odds ratio = 2.905, p  < 0.003) and > 10 years and above (adjusted odds ratio = 12.825, p  < 0.000)); district hospitals (adjusted odds ratio = 1.544, p  = 0.032); distance from place of residence (6–10 km (adjusted odds ratio = 0.090, p  < 0.001) and > 16 km (adjusted odds ratio = 0.049, p  < 0.001)); number of midwives per shift, ⩾ 4 (adjusted odds ratio = 2.396, p  = 0.012) and number of deliveries per day (6–10 (adjusted odds ratio = 1.385, p  < 0.031), 11–20 (adjusted odds ratio = 2.693, p  < 0.016) and > 20 delivery per day (adjusted odds ratio = 6.007, p  < 0.001). Conclusion: Less than half of the observed nurses and midwives had adequate skills in neonatal resuscitation. Nurses and midwives who were younger, less experienced (<4 years of work experience), and work in small, lower volume settings with fewer colleagues and limited births (dispensaries, fewer than four nurses and midwives per shift, less than six deliveries per day) were less likely to have adequate skills in neonatal resuscitation. Knowledge gained from this study may provide future research related to a cost-effective strategy to empower nurses and midwives in neonatal resuscitation.

Aurelian Anghelescu, Gelu Onose, Cristina Popescu et al.

Accumulating data suggest that chronic neuroinflammation-mediated neurodegeneration is a significant contributing factor for progressive neuronal and glial cell death in age-related neurodegenerative pathology. Furthermore, it could be encountered as long-term consequences in some viral infections, including post-COVID-19 Parkinsonism-related chronic sequelae. The current systematic review is focused on a recent question aroused during the pandemic’s successive waves: are there post-SARS-CoV-2 immune-mediated reactions responsible for promoting neurodegeneration? Does the host’s dysregulated immune counter-offensive contribute to the pathogenesis of neurodegenerative diseases, emerging as Parkinson’s disease, in a complex interrelation between genetic and epigenetic risk factors? A synthetic and systematic literature review was accomplished based on the ”Preferred Reporting Items for Systematic Principles Reviews and Meta-Analyses” (PRISMA) methodology, including registration on the specific online platform: International prospective register of systematic reviews—PROSPERO, no. 312183. Initially, 1894 articles were detected. After fulfilling the five steps of the selection methodology, 104 papers were selected for this synthetic review. Documentation was enhanced with a supplementary 47 bibliographic resources identified in the literature within a non-standardized search connected to the subject. As a final step of the PRISMA method, we have fulfilled a Population-Intervention-Comparison-Outcome-Time (PICOT)/Population-Intervention-Comparison-Outcome-Study type (PICOS)—based metanalysis of clinical trials identified as connected to our search, targeting the outcomes of rehabilitative kinesitherapeutic interventions compared to clinical approaches lacking such kind of treatment. Accordingly, we identified 10 clinical trials related to our article. The multi/interdisciplinary conventional therapy of Parkinson’s disease and non-conventional multitarget approach to an integrative treatment was briefly analyzed. This article synthesizes the current findings on the pathogenic interference between the dysregulated complex mechanisms involved in aging, neuroinflammation, and neurodegeneration, focusing on Parkinson’s disease and the acute and chronic repercussions of COVID-19. Time will tell whether COVID-19 neuroinflammatory events could trigger long-term neurodegenerative effects and contribute to the worsening and/or explosion of new cases of PD. The extent of the interrelated neuropathogenic phenomenon remains obscure, so further clinical observations and prospective longitudinal cohort studies are needed.

Chutatip Limkunakul, Benjawan Srisantithum, Yotin Lerdrattanasakulchai et al.

Background Worsening renal function (WRF) occurs in approximately 25% of acute heart failure patients, and both baseline characteristics and heart failure treatment may increase the risk of WRF. This study aimed to evaluate additional risk factors for WRF in acute heart failure, particularly those related to heart failure treatment. Methods This was a retrospective, observational, analytical study. The inclusion criteria were age 18 years or over, hospital admission due to acute heart failure, and having undergone at least two serum creatinine tests during admission. The eligible patients were classified into two groups: WRF and non-WRF. Predictors for WRF (including treatment parameters) were determined using logistic regression analysis. Results During the study period, there were 301 eligible patients who met the study criteria. Of those, 82 (27.24%) had WRF. There were two independent factors associated with WRF occurrence: baseline diastolic blood pressure and beta blocker treatment, with adjusted odds ratios (95% confidence interval) of 1.060 (1.008, 1.114) and 0.064 (0.006, 0.634), respectively. The Hosmer-Lemeshow Chi square for the final model was 6.11 (p = .634).   Conclusions After examining several heart failure treatments and baseline factors, we found that beta blocker treatment results improvement in kidney function.

Cristina Buigues, Ana Queralt, Jose Antonio De Velasco et al.

Background: Coronary heart disease (CHD) persists as the leading cause of death worldwide. Cardiovascular prevention and rehabilitation (CVPR) has an interdisciplinary focus, and includes not only in physiological components, but it also addresses psycho-social factors. Methods: The study analysed the Spanish psycho-social data collected during the EUROACTION study. In Spain, two hospitals were randomised in the Valencia community. Coronary patients were prospectively and consecutively identified in both hospitals. The intervention hospital carried out a 16-week CVPR programme, which aimed to assess illness perceptions and establish healthy behaviours in patients and their partners. Results: Illness perceptions were significantly and inversely associated with anxiety and depression. Low levels of anxiety were associated with better self-management of total cholesterol (<i>p</i> = 0.004) and low-density lipoprotein-cholesterol (<i>p</i> = 0.004). There was concordance at one year among patients and partners who participated in the programme related to anxiety (<i>p</i> < 0.001), fruit consumption (<i>p</i> < 0.001), and vegetable consumption (<i>p</i> < 0.001). Conclusions: The EUROACTION study emphasised the importance of assessing psycho-social factors in a CVPR programme and the inclusion of family as support in patients’ changes in behaviour.

Wen‐Chun Chen, Chiu‐Chu Lin, Chia‐Chen Wu et al.

Abstract Aim The aim of this study was to probe the rigorousness of the factor structure of the HDSMI and to test the instrument's construct validity. Design Cross‐sectional study. Methods The hemodialysis unit of four hospitals in Taiwan provided data from 628 patients with end‐stage renal disease (ESRD), through the period of September to December in 2012. The patients were divided into a calibration sample for CFA and model modification, and a validation sample for cross‐validation of the postmodification model. Goodness of fit was tested with standard fit indices. Results The four latent variables (i.e. partnership, self‐care, problem‐solving and emotional management) were verified as dimensions of HDSMI through CFA. The construct validity of the HDSMI was improved by omitting two items, allowing one inter‐item correlation and transferring the loading of one item. These modifications improved fit indices of the calibration sample. Cross‐validation of the validation sample verified the construct validity of the modified HDSMI‐18.

WANG Chen, LIU Changqing, AN Jingjing et al.

E. Wright

V. Henderson

G. Acs, G. Lodolini, S. Kaminsky et al.