Hasil untuk "Men"

F. Hamdy, J. Donovan, J. Lane et al.

R. Siegel, C. DeSantis, A. Jemal

A. Jemal, R. Siegel, Elizabeth E. Ward et al.

Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute and mortality data from the National Center for Health Statistics. Incidence and death rates are age‐standardized to the 2000 US standard million population. A total of 1,399,790 new cancer cases and 564,830 deaths from cancer are expected in the United States in 2006. When deaths are aggregated by age, cancer has surpassed heart disease as the leading cause of death for those younger than age 85 since 1999. Delay‐adjusted cancer incidence rates stabilized in men from 1995 through 2002, but continued to increase by 0.3% per year from 1987 through 2002 in women. Between 2002 and 2003, the actual number of recorded cancer deaths decreased by 778 in men, but increased by 409 in women, resulting in a net decrease of 369, the first decrease in the total number of cancer deaths since national mortality record keeping was instituted in 1930. The death rate from all cancers combined has decreased by 1.5% per year since 1993 among men and by 0.8% per year since 1992 among women. The mortality rate has also continued to decrease for the three most common cancer sites in men (lung and bronchus, colon and rectum, and prostate) and for breast and colon and rectum cancers in women. Lung cancer mortality among women continues to increase slightly. In analyses by race and ethnicity, African American men and women have 40% and 18% higher death rates from all cancers combined than White men and women, respectively. Cancer incidence and death rates are lower in other racial and ethnic groups than in Whites and African Americans for all sites combined and for the four major cancer sites. However, these groups generally have higher rates for stomach, liver, and cervical cancers than Whites. Furthermore, minority populations are more likely to be diagnosed with advanced stage disease than are Whites. Progress in reducing the burden of suffering and death from cancer can be accelerated by applying existing cancer control knowledge across all segments of the population.

K. Ho, J. Pinsky, W. Kannel et al.

Congestive heart failure has become an increasingly frequent reason for hospital admission during the last 2 decades and clearly represents a major health problem. Data from the Framingham Heart Study indicate that the incidence of congestive heart failure increases with age and is higher in men than in women. Hypertension and coronary heart disease are the two most common conditions predating its onset. Diabetes mellitus and electrocardiographic left ventricular hypertrophy are also associated with an increased risk of heart failure. During the 1980s, the annual age-adjusted incidence of congestive heart failure among persons aged > or = 45 years was 7.2 cases/1,000 in men and 4.7 cases/1,000 in women, whereas the age-adjusted prevalence of overt heart failure was 24/1,000 in men and 25/1,000 in women. Despite improved treatments for ischemic heart disease and hypertension, the age-adjusted incidence of heart failure has declined by only 11%/calendar decade in men and by 17%/calendar decade in women during a 40-year period of observation. In addition, congestive heart failure remains highly lethal, with a median survival time of 1.7 years in men and 3.2 years in women and a 5-year survival rate of 25% in men and 38% in women.

E. Bixler, A. Vgontzas, Hung-Mo Lin et al.

G. Becker

A. Clark

H. Ibarra

H. Arendt

Sana Khalil

This paper examines how gender and residential socioeconomic status shape hiring outcomes in the information technology sector using a field experiment from the city of Karachi, Pakistan. Employers in Pakistan can openly state preferences regarding gender, residential location, and other characteristics, but the majority in the information technology sector choose not to do so. This creates an opportunity to examine whether discrimination persists when such biases are not explicitly stated. An analysis of explicitly gender-targeted job ads shows that men are preferred over women across most occupations, even in traditionally pink-collar roles. Moreover, results from a resume audit experiment, submitting 2,032 applications to 508 full-time job openings, show that men receive more callbacks for job interviews than women, even in the absence of explicit gender preferences in job ads. The study also indicates a significant premium favoring candidates from high-income areas, who receive 45 percent more callbacks than applicants from low-income neighborhoods. This advantage remains robust even after controlling for commuting distance. Qualitative interviews with human resource officials suggest that employers associate productivity with both gender and neighborhood socioeconomic status. Residential address acts as a proxy for class background and signals education, skills, and perceived "fit" in professional settings. These perceptions may reinforce stereotypes, disadvantaging women and candidates from low-income backgrounds.

Elina Van Kempen, Ismat Jarin, Chloe Georgiou

Generative AI (GenAI) systems and chatbots rely on vast corpora of consumer data. The use of such data for training GenAI has raised concerns around data ownership, copyright issues, and potential harm to consumers. In this work, we explore a related but less examined angle: the ownership and privacy of data originating from deceased individuals. We propose three post mortem data management principles to guide the protection of deceased individual's data, and analyze popular GenAI chatbots policies and answers to legacy requests. We plan to systematically audit consumer GenAI chatbots on their behavior regarding post-mortem data management

Till Hoffmann, Jukka-Pekka Onnela

Characterizing sexual contact networks is essential for understanding sexually transmitted infections, but principled parameter inference for mechanistic network models remains challenging. We develop a discrete-time simulation framework that enables parameter estimation using approximate Bayesian computation. The interpretable model incorporates relationship formation, dissolution, concurrency, casual contacts, and population turnover. Applying our framework to survey data from 403 men who have sex with men in Stockholm, we provide principled uncertainty quantification for key network dynamics. Our analysis estimates the timescale for seeking a new steady relationship at 25 weeks and for relationship dissolution at 42 weeks. Casual contacts occur more frequently for single individuals (every 1.8 weeks) than for partnered individuals (every 4.5 weeks). However, while cross-sectional data constrains these parameters, migration rates remain poorly identified. We demonstrate that simple longitudinal data can resolve this issue. Tracking participant retention between survey waves directly informs migration rates, though survey dropout is a potential confounder. Furthermore, simple binary survey questions can outperform complex timeline follow-back methods for estimating contact frequencies. This framework provides a foundation for uncertainty quantification in network epidemiology and offers practical strategies to improve inference from surveys, the primary data source for studying sexual behavior.

Rrubaa Panchendrarajan, Harsh Saxena, Akrati Saxena

This study investigates gender-based differences in online communication patterns of academics, focusing on how male and female academics represent themselves and how users interact with them on the social media platform X (formerly Twitter). We collect historical Twitter data of academics in computer science at the top 20 USA universities and analyze their tweets, retweets, and replies to uncover systematic patterns such as discussed topics, engagement disparities, and the prevalence of negative language or harassment. The findings indicate that while both genders discuss similar topics, men tend to post more tweets about AI innovation, current USA society, machine learning, and personal perspectives, whereas women post slightly more on engaging AI events and workshops. Women express stronger positive and negative sentiments about various events compared to men. However, the average emotional expression remains consistent across genders, with certain emotions being more strongly associated with specific topics. Writing-style analysis reveals that female academics show more empathy and are more likely to discuss personal problems and experiences, with no notable differences in other factors, such as self-praise, politeness, and stereotypical comments. Analyzing audience responses indicates that female academics are more frequently subjected to severe toxic and threatening replies. Our findings highlight the impact of gender in shaping the online communication of academics and emphasize the need for a more inclusive environment for scholarly engagement.

Agneta Blomberg, Gunnel Hensing, Monica Bertilsson et al.

Abstract Background Mental health problems are common in the working-age population. More knowledge is needed on how to support work participation and reduce sickness absence. The objective of the study was to estimate the distribution of mental well-being and work capacity in women and men in a working population and assess the association between mental well-being and work capacity, while adjusting for sociodemographic characteristics, health status, and working positions. Methods Cross-sectional data were collected through an online survey distributed to individuals who were currently working. The study population consisted of 8462 employees (58% women). The WHO-5 Mental Well-being Index (scale ranging from 0 to 100 with higher scores representing a better mental well-being) and the Capacity to Work Instrument (C2WI) (scale ranging from 14 to 56 with higher scores representing a more strained work capacity) were used. Univariable and multivariable linear regressions were used to assess the associations between self-perceived mental well-being and capacity to work, adjusting for sociodemographic characteristics, health status, and working positions. Results Low self-perceived mental well-being and strained work capacity were more common among women, particularly younger aged (18–34 years). Poor health status was associated with strained work capacity in both men and women. Regression analyses showed that lower self-perceived mental well-being was significantly associated with strained work capacity. Among women, the fully adjusted model showed a regression coefficient (B) of − 0.253 (95% CI: −0.264 to − 0.242); among men, it was − 0.225 (95% CI: −0.237 to − 0.213). Conclusions This study, focusing on a currently working population, identified disparities in self-perceived mental well-being and work capacity across gender and age groups. These findings underscore the importance of early workplace interventions to support mental well-being and work capacity in these sub-groups. Notably, the association between the WHO-5 and C2WI may be partly attributable to item-level overlap, as certain C2WI items may capture symptoms related to mental health. This potential overlap should be considered when interpreting the findings.

J. Matias Bardales-Rodríguez, Flavia Rioja-Torres, Akram Hernández-Vásquez et al.

Objective: Assess the association between having witnessed physical violence between parents and intimate partner violence (IPV) against men in Bolivian adults according to the Encuesta de Demografia y Salud (EDSA) 2016. Methods: A retrospective cross-sectional study was conducted using data from the EDSA 2016 in Bolivia. The variable of interest in this study was IPV in men experienced during the last 12 months (any type of violence, physical and/or sexual, and psychological). The exposure variable was having witnessed physical violence between parents. Unadjusted and adjusted generalized linear models were constructed to assess the association of interest, and prevalence ratios (PR) with 95 % confidence intervals (95 %CI) were reported. Results: Witnessing physical aggression between parents in childhood was associated with a greater probability of suffering intimate partner violence in adulthood (adjusted PR [aPR]: 1.50; 95 %CI: 1.34–1.69). Similarly, the presence of physical aggression between parents in childhood was associated with a higher probability of physical and/or sexual violence (aPR: 1.92; 95 %CI: 1.53–2.39) and psychoverbal violence (PR: 1.48; 95 %CI: 1.32–1.67). The association identified was not modified by having suffered violence during childhood. Conclusions: Participants who witnessed physical violence between parents were more likely to suffer intimate partner violence (IPV), psycho-verbal violence and physical and/or sexual violence by their partners.

Dirk A. Moser, Tobias Tertel, Fabian Berg et al.

Abstract Maladaptive stress responses are associated with a variety of psychological and physical disorders, often characterized by molecular indicators of dysregulated stress pathways. Small extracellular vesicles (sEVs), which play a key role in intercellular communication, may be critically involved in these processes. In this study, we quantified sEV concentrations (specifically CD9+, CD63+, and CD81+ markers) in the plasma of twenty young, healthy men before and after exposure to both acute psychosocial and physical stress, using imaging flow cytometry (IFCM). Both stressors induced significant increases in cortisol, catecholamines, and cell-free DNA (cfDNA) in all participants. sEVs, however, were elevated only after physical stress, showing a rapid rise particularly in CD9- and CD63-positive vesicles, followed by a return to baseline within 40 min. In contrast, psychosocial stress elicited highly heterogeneous, non-directional sEV responses. Recursive partitioning further revealed clearly distinct sEV patterns for psychosocial and physical stress, with the highest discriminatory power observed for CD44⁺ sEVs. These findings support the existence of stressor-specific sEV signatures that could serve as future biomarkers of individual stress experience and act as effectors of distinct signal transduction pathways in both psychosocial and physical stress.

K. Hymes, J. Greene, A. Marcus et al.

Khandaker Tasnim Huq, Giovanni Luca Ciampaglia

Communities on the web rely on open conversation forums for a number of tasks, including governance, information sharing, and decision making. However these forms of collective deliberation can often result in biased outcomes. A prime example are Articles for Deletion (AfD) discussions on Wikipedia, which allow editors to gauge the notability of existing articles, and that, as prior work has suggested, may play a role in perpetuating the notorious gender gap of Wikipedia. Prior attempts to address this question have been hampered by access to narrow observation windows, reliance on limited subsets of both biographies and editorial outcomes, and by potential confounding factors. To address these limitations, here we adopt a competing risk survival framework to fully situate biographical AfD discussions within the full editorial cycle of Wikipedia content. We find that biographies of women are nominated for deletion faster than those of men, despite editors taking longer to reach a consensus for deletion of women, even after controlling for the size of the discussion. Furthermore, we find that AfDs about historical figures show a strong tendency to result into the redirecting or merging of the biography under discussion into other encyclopedic entries, and that there is a striking gender asymmetry: biographies of women are redirected or merged into biographies of men more often than the other way round. Our study provides a more complete picture of the role of AfD in the gender gap of Wikipedia, with implications for the governance of the open knowledge infrastructure of the web.

Florence E. Enock, Francesca Stevens, Jonathan Bright et al.

Online harms, such as hate speech, misinformation, harassment and self-harm promotion, continue to be widespread. While some work suggests that women are disproportionately affected by such harms, other studies find little evidence for gender differences in overall exposure. Here, we present preliminary results from a large, nationally representative survey of UK adults (N = 2000). We asked about exposure to 15 specific harms, along with fears surrounding exposure and comfort engaging in certain online behaviours. While men and women report seeing online harms to a roughly equal extent overall, we find that women are significantly more fearful of experiencing every type of harm that we asked about, and are significantly less comfortable partaking in several online behaviours. Strikingly, just 24% of women report being comfortable expressing political opinions online compared with almost 40% of men, with similar overall proportions for challenging certain content. Our work suggests that women may suffer an additional psychological burden in response to the proliferation of harmful online content, doing more 'safety work' to protect themselves. With much public discourse happening online, gender inequality in public voice is likely to be perpetuated if women feel too fearful to participate. Our results are important because to establish greater equality in society, we must take measures to ensure all members feel safe and able to participate in the online space.

Giuseppe Maccarrone, Gennaro Saporito, Patrizia Sucapane et al.

BackgroundGender differences in the access to advanced therapies for Parkinson’s disease (PD) are poorly investigated.ObjectiveThe objective of this study was to investigate the presence of any gender disparity in the access to advanced therapies for PD.DesignRetrospective study.MethodsData from patients with consistent access to the Parkinson’s and Movement Disorder Center of L’Aquila over the last 10-year period were screened. Patients selected for advanced therapies were included.ResultsOut of 1,252 patients, 200 (mean age ± SD 71.02 ± 9.70; 72% males; median Hoen Yahr level: 3, minimum 1 maximum 5) were selected for advanced therapies: 133 for Magnetic Resonance guided Focused Ultrasound (MRgFUS) thalamotomy (mean age ± SD 70.0 ± 8.9; 77% males), 49 for Levodopa/Carbidopa Intestinal Gel (LCIG) infusion (mean age ± SD 74.3 ± 11.4; 59% males), 12 for Deep Brain Stimulation (DBS) (mean age ± SD 71.2 ± 6.3; 75% males), and 7 for Continuous Subcutaneous Apomorphine Infusion (CSAI) (mean age ± SD 69.7 ± 5.5; 43% males). No sex differences were found in relation to age (MRgFUS group: males vs. females 70.2 ± 8.9 vs. 70.8 ± 8.9, p-value = 0.809; LCIG group: males vs. females 73.5 ± 13.0 vs. 75.5 ± 8.5, p-value = 0.557; DBS group: males vs. females 77.2 ± 8.1 vs. 67.3 ± 8.6, p-value = 0.843; CSAI group: males vs. females 73.3 ± 4.0 vs. 67.0 ± 5.2, p-value = 0.144) and disease duration (MRgFUS group: males vs. females 8.3 ± 4.4 vs. 9.6 ± 6.7, p-value = 0.419; LCIG group: males vs. females 14.5 ± 5.81 vs. 17.3 ± 5.5; p-value = 0.205; DBS group: males vs. females 15.0 ± 9.6 vs. 15.5 ± 7.7, p-value = 0.796; CSAI group: males vs. females 11.7 ± 3.7 vs. 10.3 ± 3.7, p-value = 0.505).ConclusionThe predominance of males is higher than that expected based on the higher prevalence of PD in men. Women are less confident in selecting advanced therapies during the natural progression of their disease. Factors accounting for this discrepancy deserve further investigation.