Hasil untuk "Literature (General)"

Ilker Baybars

S. Vogel

Eric Renshaw, G. White, David R. Anderson et al.

P. Besl, R. Jain

D. Powell, B. Abramson, J. Balint et al.

J. Fröhlich, D. Terzi

Michael McBride

I. Vis, R. Koster

T. Simon, A. Thompson, K. Gandhi et al.

IntroductionPatients with rheumatoid arthritis (RA) are at an increased risk of malignancies compared with the general population. This has raised concerns regarding these patients, particularly with the widespread use of immunomodulating therapies, including biologic disease-modifying antirheumatic drugs (DMARDs). We performed a systematic literature review and analysis to quantify the incidence of malignancies in patients with RA and the general population to update previously published data.MethodsA literature search was conducted that was consistent with and similar to that in a meta-analysis published in 2008. MEDLINE, BIOSIS Previews, Embase, Derwent Drug File and SciSearch databases were searched using specified search terms. Predefined inclusion criteria identified the relevant observational studies published between 2008 and 2014 that provided estimates of relative risk of malignancy in patients with RA compared with the general population. Risk data on overall malignancy and site-specific malignancies (lymphoma, melanoma and lung, colorectal, breast, cervical and prostate cancer) were extracted. The standardized incidence ratios (SIRs; a measure of risk) relative to the general population were evaluated and compared with published rates.ResultsA total of nine publications met the inclusion criteria. Seven of these reported SIRs for overall malignancy; eight for lymphoma, melanoma, and lung, colorectal and breast cancer; seven for prostate cancer; and four for cervical cancer. Compared with those in the general population, the SIR estimates for patients with RA suggest a modest increased risk in overall malignancy, as previously observed. Patients with RA continued to show an increased risk of lymphoma and lung cancer compared with the general population. Overall, SIR estimates for colorectal and breast cancers continued to show a decrease in risk, whereas cervical cancer, prostate cancer and melanoma appeared to show no consistent trend in risk among patients with RA compared with the general population.ConclusionsThe additional data evaluated here are consistent with previously reported data. Patients with RA are at an increased risk of lung and lymphoma malignancies compared with the general population. Quantifying differences in malignancy rates between non-biologic and biologic DMARD-treated patients with RA may further highlight which malignancies may be related to treatment rather than to the underlying disease.

C. Mirescu, E. Gould

J. Heckman, E. Vytlacil

K. Wilson, Wendy L. Bedwell, E. Lazzara et al.

Wanying Zhang, Jing Wang, Geng Qin et al.

The shipping industry, responsible for transporting 90% of global goods, is a major source of pollution and greenhouse gas (GHGs) emissions. In response to the increasingly stricter global and regional emission control regulations, the maritime industry has adopted various operational and technical measures to improve vessel energy efficiency so as to reduce emissions. However, these measures might not be able to effectively address the core issue of emissions, which arises from a heavy reliance on carbon-intensive energy sources. To reduce the emissions from the whole shipping industry more fundamentally, this review evaluates the viability of five alternative marine fuels — liquefied natural gas (LNG), methanol, ammonia, biofuel, and hydrogen — as potential solutions for maritime decarbonization. This review adopts the systematic search flow (SSF) approach, using iterative search refinement and thematic analysis for a structured synthesis of maritime alternative fuel literature. It first introduces each type of alternative fuel with an emphasis on production methods and sources, which are distinctively categorized by “color.” Following this, a comprehensive comparison of the fuels is presented, focusing on technical feasibility, economic viability, emission reduction capabilities, availability, and safety considerations. The practical application of these fuels is further explored through an analysis of their adoption in operational fleets and new orders, as well as the readiness of port infrastructure to support these changes. This review also examines the role of alternative fuels in the development of green shipping corridors, underscored by an analysis of green shipping finance initiatives. The findings provide valuable insights into the viability of these fuels, supporting the International Maritime Organization (IMO)’s 2050 decarbonization goals and paving the way towards zero emissions in global shipping.

Luis Miguel Rojas Berscia

En este artículo realizamos una primera y breve exploración en el repertorio epistemológico shawi/chayahuita en torno al fenómeno lingüístico. Siguiendo la línea propuesta en Favaron Peyón (2024) en aras de dar voz a distintas reflexiones poéticas, retóricas y teóricas en torno a la ‘palabra’ entre los pueblos amerindios, proveemos un primer acercamiento al concepto de nanan ‘palabra, lengua’, así como a una de las manifestaciones más íntimas de su arte y saberes, el icaro. Gracias a las reflexiones compartidas por el sabio y maestro Rafael Chanchari Pizuri, nos acercamos a la etimología, así como a la estructura discursiva del icaro. Es así que damos un primer paso hacia el diálogo entre la lingüística occidental contemporánea y lo que oso llamar una lingüística o filosofía del lenguaje shawi.

Lucas Fornari Laurindo, Victória Dogani Rodrigues, Enzo Pereira de Lima et al.

Cardiovascular diseases are the primary cause of mortality worldwide. In this scenario, atherosclerotic cardiovascular outcomes dominate since their incidence increases as populations grow and age. Atherosclerosis is a chronic inflammatory disease that affects arteries. Although its pathophysiology is heterogeneous, some genes are indissociably associated with its occurrence, and understanding their effects on the disease’s occurrence could undoubtedly define effective screening and treatment strategies. One such gene is NEDD4L. The NEDD4L gene is related to ubiquitin ligase enzyme activities. It is essential to regulate vascular inflammation, atherosclerosis plaque stability, endothelial and vascular smooth cell function, and lipid metabolism, particularly in controlling cholesterol levels. However, the evidence is dubious, and no review has yet synthesized the effects of targeting NEDD4L on atherosclerosis. Therefore, our review aims to fill this gap by analyzing the literature on NEDD4L concerning atherosclerosis occurrence. To achieve this goal, we performed a systematic literature search of reputable databases, including PubMed, Google Scholar, Web of Science, Scopus, and Embase. The inclusion criteria comprised peer-reviewed original studies using in vitro and animal models due to the unavailability of relevant clinical studies. Systematic reviews, meta-analyses, and articles that did not focus on the relationship between NEDD4L and atherosclerosis and those unrelated to this health condition were excluded. Studies not written in the English language were also excluded. The search strategy included studies from January 2000 to January 2025 in the final analysis to capture recent advancements. Following screening, five studies were included. Most of the included studies underscored NEDD4L’s role in increasing atherosclerosis plaque formation, but other studies indicated that stimulating NEDD4L may positively counter atherosclerosis plaque formation. Therefore, future research endeavors must address several limitations, which have been tentatively highlighted throughout the manuscript, for more informative research based on preclinical studies and to successfully translate the findings into clinical trials.

Hein Htet, Amgad Ahmed Ali Ibrahim, Yutaka Sasaki et al.

The oxygen reduction reaction (ORR) catalyst plays a critical role in enhancing fuel cell efficiency, making it a key focus in material science research. However, extracting structured information about ORR catalysts from vast scientific literature remains a significant challenge due to the complexity and diversity of textual data. In this study, we propose a named entity recognition (NER) and relation extraction (RE) approach using DyGIE++ with multiple pre-trained BERT variants, including MatSciBERT and PubMedBERT, to extract ORR catalyst-related information from the scientific literature, which is compiled into a fuel cell corpus for materials informatics (FC-CoMIcs). A comprehensive dataset was constructed manually by identifying 12 critical entities and two relationship types between pairs of the entities. Our methodology involves data annotation, integration, and fine-tuning of transformer-based models to enhance information extraction accuracy. We assess the impact of different BERT variants on extraction performance and investigate the effects of annotation consistency. Experimental evaluations demonstrate that the fine-tuned PubMedBERT model achieves the highest NER F1-score of 82.19% and the MatSciBERT model attains the best RE F1-score of 66.10%. Furthermore, the comparison with human annotators highlights the reliability of fine-tuned models for ORR catalyst extraction, demonstrating their potential for scalable and automated literature analysis. The results indicate that domain-specific BERT models outperform general scientific models like BlueBERT for ORR catalyst extraction.

Abhiyan Dhakal, Kausik Paudel, Sanjog Sigdel

We propose an automated pipeline for performing literature reviews using semantic similarity. Unlike traditional systematic review systems or optimization based methods, this work emphasizes minimal overhead and high relevance by using transformer based embeddings and cosine similarity. By providing a paper title and abstract, it generates relevant keywords, fetches relevant papers from open access repository, and ranks them based on their semantic closeness to the input. Three embedding models were evaluated. A statistical thresholding approach is then applied to filter relevant papers, enabling an effective literature review pipeline. Despite the absence of heuristic feedback or ground truth relevance labels, the proposed system shows promise as a scalable and practical tool for preliminary research and exploratory analysis.

Farah Luthfi Kaulina, Sukihananto Sukihananto

Non-communicable diseases (NCDs) are still a morbidity and mortality problem in Southeast Asia. However, NCD in Southeast Asia still needs to be handled faster. WHO recommends the use of digital in treating NCDs in Southeast Asia. Therefore, this literature review study aims to describe how mHealth is utilized to overcome the problem of NCDs in Southeast Asian countries. The author collected articles using Google Scholar and Proquest, which were published in 2019-2023. The focus of the search was articles published in English-language Research Journals. Researchers used advanced search with the keywords NCD, Non-communicable diseases, mHealth, Mobile Health, Nursing, and Health Promotion. Keywords are combined using Boolean and/or the online database that the researcher chose. Articles that have been filtered are filtered again by selecting research locations in Southeast Asian countries. Ten articles obtained came from research in Southeast Asian countries Indonesia (n=4), Malaysia (n=1), Singapore (n=1), Vietnam (n=1), Thailand (1), Cambodia (n=1), Philippines (n=1). All articles discussed the use of mHealth for NCD management in their countries and aimed to determine the barriers (n=3), feasibility (n=1), effectiveness (n=2), impact (n=2), potential (n=1), perception (n=1), and perspective (n=1) of service providers, as well as the experience of using mHealth in remote areas (n=1). It can be concluded that mHealth can be used for independent screening for PTM, providing education about NCDs, and can be applied in rural areas as a comprehensive effort to handle NCDs.

Alioune Diallo, Jordan Samhi, Tegawendé Bissyandé et al.

In developing countries, several key sectors, including education, finance, agriculture, and healthcare, mainly deliver their services via mobile app technology on handheld devices. As a result, mobile app security has emerged as a paramount issue in developing countries. In this paper, we investigate the state of research on mobile app security, focusing on developing countries. More specifically, we performed a systematic literature review exploring the research directions taken by existing works, the different security concerns addressed, and the techniques used by researchers to highlight or address app security issues. Our main findings are: (1) the literature includes only a few studies on mobile app security in the context of developing countries ; (2) among the different security concerns that researchers study, vulnerability detection appears to be the leading research topic; (3) FinTech apps are revealed as the main target in the relevant literature. Overall, our work highlights that there is largely room for developing further specialized techniques addressing mobile app security in the context of developing countries.

Pavel Sidorenko, Nadia Alonso López, Adriana Paíno Ambrosio

En virtud de que las redes sociales se perfilaron como fuentes de información desde el primer momento en que Rusi tomó la decisión de invadir Ucrania en febrero de 2022, la presente investigación pretende analizar, de forma exploratoria el tipo de perfiles que difundieron en una primera instancia la guerra ucraniana a través de TikTok, una red social trending basada en el entretenimiento con una narrativa caracterizada por la sátira, los retos y los bailes virales. Para ello, se utiliza un análisis cualitativo de las publicaciones realizadas en esta red social con los hashtags #Ucrania y #Ukraine teniendo en cuenta que tanto civiles como periodistas o militares hicieron uso de la plataforma. Los resultados muestran que los perfiles de los influencers son los que publican más contenido informativo y testimonial y tienen un mayor impacto que los propios medios de comunicación.