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DOAJ Open Access 2025
DP059 | AN ITALIAN CARTOGRAPHY OF VEXAS-RELATED THROMBOSIS: A 218 PATIENT-YEARS ANALYSIS

G. Ranucci, V. Forte, E. Diral et al.

While thrombotic events (TE) occur in up to 40% of VEXAS cases, a scarcity of data exists on its clinical-genomic associations or anti-coagulation strategies. To fill this gap in knowledge, we designed a two-step study aiming at elucidating prevalence, outcomes of TE in VEXAS and outline potential grounds for specific therapeutic strategies. First, we conducted a pilot-study to explore the prevalence of VEXAS in a general cohort of TE patients, taking advantage of the Thrombosis clinic (n=1086) of Rome Tor Vergata Hospital. By looking for VEXAS demographics and features, we selected 21 patients. None was positive for UBA1 mutations, suggesting that VEXAS should be suspected when specific manifestations are present, besides the mere occurrence of unexplained TE. Next, we leveraged our Italian VEXAS network to systematically investigate TE. We accrued 85 male patients, totaling 218 patient-years, with a median age of 70 years (IQR, 64-75). VEXAS co-occurred with MDS in 61% of cases, MGUS in 33%, and multiple myeloma in 1 case. Most patients presented with macrocytic anemia at diagnosis, with median hemoglobin of 9.9 g/dL (IQR, 8.4-11.4 g/dL) and MCV of 104 fL (IQR, 96-108). UBA1 genotype consisted of M41T in 43%, M41V in 33%, and M41L in 6% of cases while 18% carried other mutations. Overall, 53% of patients experienced TE, mostly affecting the venous system (78%). These were in majority of cases (62%) DVT, 10% PE, while 2 cases occurred in the splanchnic veins. About 18% of patients exhibited arterial thrombosis, mostly as cardiac events while in 1 case thrombosis involved the central retinal artery. With regards to timing of TE, this was synchronous with the VEXAS diagnosis in 67% of cases, antecedent in 7% while the others (26%) were identified subsequently. No baseline clinical nor molecular (UBA1 genotype) characteristic associated with TE. Notably, 10% of patients had concomitant thrombophilic conditions (3 heterozygous Factor V Leiden, 1 heterozygous Factor II G20210A, 5 anti-cardiolipin IgG/M antibodies). The therapeutic approach of TE consisted of DOACs in 47% of cases, LMWH in 26%, Fondaparinux in 17%, and VKAs in 7%. Longitudinal follow up revealed a complete resolution of TE in 76% of cases, while 14% had >1 TE with 4% occurring while on anti-coagulation. TE and thrombophilia are common in patients with VEXAS and are not associated with any baseline characteristics, prompting screening early at diagnosis for adequate management.

Diseases of the blood and blood-forming organs
DOAJ Open Access 2025
Stakeholders’ feedback integration in spatial planning using Importance Performance Analysis: the case of the Provincial Strategic Plan of the Autonomous Province of Bolzano-South Tyrol (IT)

Elisa Ravazzoli, Cristina Dalla Torre, Alice Labadini et al.

Importance Performance Analysis (IPA) is a research method employed to comprehend and analyze stakeholder feedback on particular issues. A substantial body of research has demonstrated the efficacy of this methodology as a quantitative approach. To date, there has been a paucity of research using IPA as a methodology for integrating stakeholder feedback into the development of strategic spatial plans. The integration of stakeholder feedback is crucial for the development of inclusive, well-informed, and responsive decision-making processes. The objective of this paper is to contribute to the existing body of knowledge on the utilization of the IPA method in the context of spatial planning. This research presented in this paper employs the Provincial Strategic Plan of the Autonomous Province of Bolzano-Bozen as a case study. In particular, the IPA method was employed to analyze the level of importance and performance of the objectives set out in the Provincial Strategic Plan. Importance refers to the importance of the specific objectives for the future development of the area, while performance refers to how well the specific objectives were formulated. The IPA method has been demonstrated to be an effective assessment instrument. The findings demonstrate that the IPA approach enabled the effective gathering of stakeholders’ feedback in a systematic manner, identifying pivotal issues and potential shortcomings, and providing policy makers with structured recommendations on how to reformulate strategies and plans.

Science (General), Social sciences (General)
DOAJ Open Access 2023
Local Infrasound Monitoring of Lava Eruptions at Nyiragongo Volcano (D.R. Congo) Using Urban and Near‐Source Stations

Julien Barrière, Adrien Oth, Nicolas d’Oreye et al.

Abstract During eruptions, volcanoes produce air‐pressure waves inaudible for the human ear called infrasound, which are very helpful for detecting early signs of magma at the surface. Compared to violent ash‐rich explosions, recording more discrete atmospheric disturbances from effusive eruptions remains a practical challenge depending on the distance to the source. At Nyiragongo volcano (D.R. Congo), towering above a 1‐million urban area, we analyzed local infrasonic records between January 2018 and April 2022. An acoustic signature from this open‐vent volcano is detected up to the volcano observatory facilities in Goma city center about 17 km from its crater. We compared infrasound signals with space‐based observations of the intra‐crater activity (SO2 emissions, thermal anomalies, crater depth/radius). We thus obtain a comprehensive picture of Nyiragongo's eruptive activity during this period, encompassing the drainage of its lava lake during its third known flank eruption on 22 May 2021.

Geophysics. Cosmic physics
DOAJ Open Access 2023
Luojia-HSSR: A high spatial-spectral resolution remote sensing dataset for land-cover classification with a new 3D-HRNet

Yue Xu, Jianya Gong, Xin Huang et al.

ABSTRACTHigh Spatial and Spectral Resolution (HSSR) remote-sensing images can provide rich spectral bands and detailed ground information, but there is a relative lack of research on this new type of remote-sensing data. Although there are already some HSSR datasets for deep learning model training and testing, the data volume of these datasets is small, resulting in low classification accuracy and weak generalization ability of the trained models. In this paper, an HSSR dataset Luojia-HSSR is constructed based on aerial hyperspectral imagery of southern Shenyang City of Liaoning Province in China. To our knowledge, it is the largest HSSR dataset to date, with 6438 pairs of 256 × 256 sized samples (including 3480 pairs in the training set, 2209 pairs in the test set, and 749 pairs in the validation set), covering area of 161 km2 with spatial resolution 0.75 m, 249 Visible and Near-Infrared (VNIR) spectral bands, and corresponding to 23 classes of field-validated ground coverage. It is an ideal experimental data for spatial-spectral feature extraction. Furthermore, a new deep learning model 3D-HRNet for interpreting HSSR images is proposed. The conv-neck in HRNet is modified to better mine the spatial information of the images. Then, a 3D convolution module with attention mechanism is designed to capture the global-local fine spectral information simultaneously. Subsequently, the 3D convolution is inserted into the HRNet to optimize the performance. The experiments show that the 3D-HRNet model has good interpreting ability for the Luojia-HSSR dataset with the Frequency Weighted Intersection over Union(FWIoU) reaching 80.54%, indicating that the Luojia-HSSR dataset constructed in this paper and the proposed 3D-HRnet model have good applicable prospects for processing HSSR remote sensing images.

Mathematical geography. Cartography, Geodesy
DOAJ Open Access 2021
Music and Corporeal Mimesis: creative frictions for the dramaturgy of the musician-actuator

Eduardo Conegundes Souza

Built as a cartographic report, this article aims to give insight to the practical and conceptual procedures carried out during the research process that culminated in the scenic and musical creation of the show Uji – O Bom da Roda. Based on the cartographic method, we focus on encounters and contaminations produced between the theatrical universe and the roda de samba (samba circle) in its multiple expressive dimensions. Within a territory of creative frictions, Corporeal Mimesis presented itself as a fundamental element of articulation between music, body, scene and dramaturgy.

Drama, Dramatic representation. The theater
DOAJ Open Access 2020
Change in regional land subsidence in Beijing after south-to-north water diversion project observed using satellite radar interferometry

Mingyuan Lyu, Yinghai Ke, Lin Guo et al.

Over-exploitation of groundwater has caused severe land subsidence in Beijing during the past two decades. Since the middle route of South-to-North Water Diversion Project (SNWDP), the biggest water diversion project in China, started to deliver water to Beijing in December 2014, the groundwater shortage has been greatly alleviated. This study aims to analyze the impact of SNWDP on the spatiotemporal evolution of land subsidence in Beijing. Change in surface displacement in Beijing after SNWDP was retrieved and the spatiotemporal patterns of the change were analyzed based on long time-series Envisat Advanced Synthetic Aperture Radar (ASAR) (2004–2010), Radarsat-2 (2011–2014), and Sentinel-1 (2015–2017) satellite datasets using Permanent Scatterer Interferometric Synthetic Aperture Radar (PS-InSAR) techniques. Land subsidence unevenness index (LSUI) was proposed to represent the spatial unevenness of surface displacement. PS-Time approach was then adapted to examine the time series evolution of LSUI. The results showed that the InSAR measurements agree well with leveling measurements with R2 over 0.96. Although the maximum annual displacement rate reached −159.7 mm/year by 2017, over 57% of the area within 25 mm/year contour line showed decreasing or unchanged displacement rate after the south-north water delivered to Beijing. The settlement rate in Chaoyang-Dongbalizhuang (CD) subsidence center has decreased for 26 mm/year from 2011–2014 to 2015–2017. Only around 15% of the area experienced continued accelerating settlement rate through the three time periods, which was mainly located in the area with the compressible layer thickness over 190 m, while the magnitude of velocity increment considerably decreased after SNWDP. Land subsidence unevenness, represented by LSUI, developed more slowly after SNWDP than that during 2011–2014. However, LSUI at the edge of settlement funnel has kept developing and reached 1.7‰ in 2017. Decreasing groundwater level decline after SNWDP and the positive relationship (R2 > 0.74) between land subsidence and groundwater level clearly showed impacts of SNWDP on the alleviating land subsidence. Other reasons include geological background, increasing precipitation, and strict water management policies implemented during these years.

Mathematical geography. Cartography, Environmental sciences
DOAJ Open Access 2019
Evaluation of five gridded rainfall datasets in simulating streamflow in the upper Dong Nai river basin, Vietnam

Pham Thi Thao Nhi, Dao Nguyen Khoi, Nguyen Xuan Hoan

Rainfall data with an appropriate spatial resolution is a key input to hydrological models. However, networks of rain gauges are often sparsely and unevenly distributed in large catchments, especially in developing countries. High-resolution rainfall datasets, such as the Asian Precipitation Highly Resolved Observational Data Integration Towards Evaluation of Water Resources (APHRODITE), the Climate Forecast System Reanalysis (CFSR), the Climatic Research Unit Time Series (CRU-TS), the Global Precipitation Climatology Centre (GPCC) and the Tropical Rainfall Measuring Mission (TRMM), have become available to overcome such limitations. The objective of this study was to evaluate the impacts of four land-based rainfall products (APHRODITE, CFSR, CRU-TS, and GPCC) and a satellite-based rainfall product (TRMM) on streamflow of the upper catchment of Tri An reservoir in Vietnam using the Hydrological Modeling System (HEC-HMS). In addition, the available rain gauges data were used for comparison purpose. Result indicates that the TRMM and GPCC data show their best match to rain gauges data in simulating the streamflow in the period 1999–2007. Generally, the results indicate that the TRMM and GPCC data could be alternative solutions.

Mathematical geography. Cartography
DOAJ Open Access 2017
Evaluation of selected maps used in early school education in Poland and proposal of a new solution

Słomska Katarzyna

The author presents criteria of evaluation and assumption for early school education maps. Attention was payed to needs and perceptual possibilities of map users and cartographic correctness of maps. Main criteria of map evaluation – content and form of a map – have their unique attributes. In case of the first criterion they are accuracy and currency, classification of content and usability. Second criterion consist of: composition, colours, labels on the map and readability. Materials commissioned by Ministry of National Education were evaluated on the said criteria basis. Evaluation of maps for early school education revealed their flaws, among which absence of a scale can be named. Afterwards assumptions were developed and used to prepare own proposal of a map. Achieving maximum readability was a priority. Other assumptions concerned graphic balance, classification and hierarchy of content, simplicity of elaboration, usage of readable typefaces and adjustment of transmission to the age of users.

DOAJ Open Access 2016
Geodetski časopisi u Emerging Sources Citation Indexu

Nedjeljko Frančula

Thomson Reuters uz već poznate citatne indekse Science Citation Index Expanded (SCIE), Social Science Citation Index (SSCI) i Arts &Humanities Citation Index (A&HCI) izrađuje od 2015. i novi indeks Emerging Sources Citation Index (ESCI) – sve uključene u Web of Science. U ESCI su uvršteni časopisi od regionalne važnosti i časopisi iz znanstvenih područja u nastajanju. Časopisi uvršteni u ESCI bit će nakon određenog vremena, ako zadovolje kriterije Thomson Reutersa, uvršten u SCIE, SSCI ili A&HCI. Za časopise uvrštene u ESCI, trenutno ih je 2589, ne izračunava se faktor odjeka.

Cartography
DOAJ Open Access 2014
The Application Of Open-Source And Free Photogrammetric Software For The Purposes Of Cultural Heritage Documentation

Bartoš Karol, Pukanská Katarína, Sabová Janka

The documentation of cultural heritage is an essential part of appropriate care of historical monuments, representing a part of our history. At present, it represents the current issue, for which considerable funds are being spent, as well as for the documentation of immovable historical monuments in a form of castle ruins, among the others. Non-contact surveying technologies - terrestrial laser scanning and digital photogrammetry belong to the most commonly used technologies, by which suitable documentation can be obtained, however their use may be very costly. In recent years, various types of software products and web services based on the SfM (or MVS) method and developed as open-source software, or as a freely available and free service, relying on the basic principles of photogrammetry and computer vision, have started to get into the spotlight. By using the services and software, acquired digital images of a given object can be processed into a point cloud, serving directly as a final output or as a basis for further processing. The aim of this paper, based on images of various objects of the Slanec castle ruins obtained by the DSLR Pentax K5, is to assess the suitability of different types of open-source and free software and free web services and their reliability in terms of surface reconstruction and photo-texture quality for the purposes of castle ruins documentation.

DOAJ Open Access 2012
CADASTRO MULTIFINALITÁRIO 3D: CONCEITOS E PERSPECTIVAS DE IMPLANTAÇÃO NO BRASIL

Andrea Flávia Tenório Carneiro, Diego Alfonso Erba, Eduardo Agostinho Arruda Augusto

A situação do cadastro territorial brasileiro é complexa, pois sua estrutura é constituída por um cadastro rural, centralizado e gerenciado pelo Governo Federal, e por diversos cadastros urbanos que se encontram sob a responsabilidade direta das administrações municipais. O marco legislativo vigente está orientado à multifinalidade, estrutura que não termina por consolidar-se. Este artigo analisa os aspectos jurídicos e administrativos envolvidos na implementação de um cadastro multifinalitário incorporando a visão espacial e propondo conceitos de parcela e objetos territoriais.

Geography. Anthropology. Recreation, Cartography
DOAJ Open Access 2010
Venice GIS Portal: la punta dell'iceberg

Rudj Maria Todaro

Venice GIS portal Single information system, the only methodology but an undetermined number of working groups. The basic principle, which underpins Insula, is flexibility, a philosophy which has enabled it to test the adoption of new processes of governance of assets, as a strategic resource of the Public.

Cartography, Cadastral mapping
DOAJ Open Access 2010
La documentazione territoriale tra innovazione e tradizione

Domenico Santarsiero

Land documentation between tradition and innovation Microgeo and Geosoft organized a workshop that was attended by many professionals of different nature and extraction. Topography and spatial asset detectors, cartographers and producers of spatial data as operators in the field of aerial photogrammetry and simple insiders as who wrote.

Cartography, Cadastral mapping
DOAJ Open Access 2010
Les types de climats en France, une construction spatiale

Daniel Joly, Thierry Brossard, Hervé Cardot et al.

The climatic criterion impacts the behaviour and the decision of individuals and social groups; thus, it is a major component of the territory life. Therefore, dividing space according to different climate types is worth achieving by using updated data processing resources. With this aim in view, the authors suggest a spatial approach for defining climates and their geographical limits. Taking into account measurements made by Météo-France recording stations, a data set related to temperature and precipitation is worked out for a 30 years period (1971-2000), it includes 14 variables able to characterize the climates and their specific variability. An original method, so called local interpolation, allows the representation of each of the 14 variables as a continuous field and stores them in the form of GIS data layers. This data is then processed by Coupling Correspondence Analysis and Ascending Hierarchical Classification in order to obtain a typology where 8 climates are identified and mapped on the French continental territory. An additional process using a probabilistic method enables the mapping of the potential distribution space of each climate and the shading of the strict type delimitation the way it is given by classification. A final synthesis leads to interpret the obtained results within the frame of a general climate understanding. Two annexes enable the download of the cartographic documentation related to this paper.

Geography (General)
DOAJ Open Access 2009
OpenStreetMap e la prima conferenza OSMit

Luca Dellucchi, Niccolò Rigacci, Paolo Cavallini

OpenStreetMap and the first OSMit conference This month’s article features a brief presentation of the OpenStreetMap project, initiated by a single user in 2004 with the aim of creating a free map of the world, editable following wiki-like rules, and evolved in a few years in a system involving over 100,000 users contributing data from all over the world. The interest in presenting this topic is related also to the recent occurrence of the first meeting of the Italian OpenStreetMap Community. The meeting took place in Trento in early June 2009, organized by the Fondazione Bruno Kessler, and demonstrated the liveliness of this community, showcasing experience conducted over the past year, and highlighting developments for the future.

Cartography, Cadastral mapping

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