Hasil untuk "Office management"

Menampilkan 20 dari ~13127713 hasil · dari DOAJ, CrossRef, Semantic Scholar

JSON API
DOAJ Open Access 2024
Research on Nanliu River Integrated Information Management System Based on Land and Sea Integration

PAN Jie, LI Shushi, YANG Xialing et al.

The construction of integrated basin information management model based on land and sea coordination is the key content to realize the coordinated development of basin environmental governance and coastal economic and social development. Taking Nanliu River Basin as an example, based on the analysis of the key problems in the current basin environmental management process, this paper discusses the implementation of comprehensive basin management from the perspective of land-sea coordination, including the design of comprehensive information database, data requirement analysis, system function research, etc., and then puts forward specific strategies for building an integrated information management system for Nanliu River. In order to provide scientific theory and decision-making basis for regional economic and social development and disaster prevention and reduction.

Oceanography
DOAJ Open Access 2024
Reduction of the Risk of Hepatocellular Carcinoma over Time Using Direct-Acting Antivirals: A Propensity Score Analysis of a Real-Life Cohort (PITER HCV)

Maria Giovanna Quaranta, Luisa Cavalletto, Francesco Paolo Russo et al.

The treatment of hepatitis C virus (HCV) with direct-acting antivirals (DAA) leads to high sustained virological response (SVR) rates, but hepatocellular carcinoma (HCC) risk persists in people with advanced liver disease even after SVR. We weighted the HCC risk in people with cirrhosis achieving HCV eradication through DAA treatment and compared it with untreated participants in the multicenter prospective Italian Platform for the Study of Viral Hepatitis Therapies (PITER) cohort. Propensity matching with inverse probability weighting was used to compare DAA-treated and untreated HCV-infected participants with liver cirrhosis. Kaplan–Meier analysis and competing risk regression analysis were performed. Within the first 36 months, 30 de novo HCC cases occurred in the untreated group (<i>n</i> = 307), with a weighted incidence rate of 0.34% (95%CI: 0.23–0.52%), compared to 63 cases among SVR patients (<i>n</i> = 1111), with an incidence rate of 0.20% (95%CI: 0.16–0.26%). The 12-, 24-, and 36-month HCC weighted cumulative incidence rates were 6.7%, 8.4%, and 10.0% in untreated cases and 2.3%, 4.5%, and 7.0% in the SVR group. Considering death or liver transplantation as competing events, the untreated group showed a 64% higher risk of HCC incidence compared to SVR patients (SubHR 1.64, 95%CI: 1.02–2.62). Other variables independently associated with the HCC occurrence were male sex, increasing age, current alcohol use, HCV genotype 3, platelet count ≤ 120,000/µL, and albumin ≤ 3.5 g/dL. In real-life practice, the high efficacy of DAA in achieving SVR is translated into high effectiveness in reducing the HCC incidence risk.

DOAJ Open Access 2024
KADO SPESIAL: Strategic Innovation for Conservation Area Management in Pieh Island National Marine Protected Area, West Sumatra

Rahmat Irfansyah, Muh. Firdaus Agung Kunto Kurniawan, R. Hernan Mahardhika et al.

The Pieh Island National Marine Protected Area (NMPA) is managed by the LKKPN (National Marine Protected Area Office) Pekanbaru and includes distinct zones: a 197.34-hectare core zone, a 39,681.1-hectare limited utilization zone, and a 41.56-hectare anchoring and habitat rehabilitation zone. The largest, the limited utilization zone, highlights the importance of managing human interactions within the MPA. This research focuses on identifying and exploring strategies to address challenges faced by LKKPN Pekanbaru in managing the Pieh Island NMPA, specifically using the Bando Island area as a case study. Bando Island, a survival tourism destination within the MPA, needs to be more adequately managed. A literature review and data collection through focus group discussions (FGD) were conducted. Issues were explored and validated using the APKL (Aktual, Problematik, Khalayak, Layak) analysis, with priorities determined by the USG (Urgency, Seriousness, Growth) matrix. Fishbone analysis was used to identify root causes of top-priority issues, and alternative strategies were ranked using the McNamara approach. The research identified the lack of stakeholder collaboration as the primary issue, leading to the development of the "KADO SPESIAL" model—focusing on stakeholder involvement in every phase of the management process.

Social Sciences
DOAJ Open Access 2024
Implementasi Pengadaaan Sarana Dan Prasarana Pendidikan Madrasah Dengan SIM-SARPRAS

Nabila Jovani Putri, Walid Fajar Antariksa

Management of procurement of facilities and infrastructure is very important in supporting the smooth implementation of teaching and learning activities to be effective and efficient for each educational institution unit. The Ministry of Religion of the Republic of Indonesia has created the Madrasah Infrastructure Information System (SIM-SARPRAS) application to regulate the management of submission of assistance for facilities and infrastructure submitted by all madrasas or educational institutions in Indonesia. This study aims to analyze the implementation of SIM-SARPRAS procurement of facilities and infrastructure. This study uses a qualitative approach with field research type. The research data was obtained from the results of interviews, observations and documentation. The results of this study are that the process of submitting assistance for procurement of facilities and infrastructure with the SIM-SARPRAS application has used the established Standard Operating Procedure (SOP). The process begins with schools submitting proposals for requests for school facilities and infrastructure which are entered through the SIM-SARPRAS application, then the Batu City Ministry of Religion Office will check and provide recommendations to the madrasah to be forwarded to the East Java Provincial Ministry of Religion Regional Office which will then forward it to the Ministry of Religion. Once approved, the madrasah will receive a budget that will be sent directly to the account to be used in procurement. After the procurement is complete, the madrasah will make an accountability report. This SIM-SARPAS application makes the process of submitting procurement of facilities and infrastructure from madrasahs to the government faster and more practical compared to the previous manual process, which took longer. However, there are still things that need to be improved, such as the long submission stages that take a long time, and the difficulty of monitoring whether the submission status has been verified or approved, because this can only be known by the central operator.

Social sciences (General)
DOAJ Open Access 2023
Special prosecutor: Panacea or facade to institutionalised corruption in Ghana?

Olivia Anku-Tsede, Reginald Arthur, Majoreen Osafroadu Amankwah

Motivated by the systematic nature of corruption and effect on the nation’s potential, this study sought to assess how the establishment of the Office of the Special Prosecutor (OSP) aids in its fight. Further, it comparatively analyses this agency vis-à-vis other agencies with a similar mandate to determine whether the role of the special prosecutor makes any impact in fighting this cancer. Data was collected through interviews from professionals in the law fraternity and analysed using content analysis. Findings are that the OSP is indeed an independent prosecutor who could be regarded as free from the influence of the executive with no conflict of interest in carrying out its mandate. Further, the study found that there was dissatisfaction with the performance of the OSP due to its inability to prosecute enough high-profile cases. However, due to the commitment and track record of the OSP, many expressed confidence in his person to help wrestle corruption. Many, however, were of the view that there were overlapping and conflicting functions between the OSP and other state anti-corruption agencies. Unfortunately, the office is saddled with many challenges inhibiting the performance of its mandate, thereby questioning whether it is a panacea or facade to institutionalised corruption in Ghana.

Social Sciences
DOAJ Open Access 2023
Study on Training Path of Outstanding Marine Legal Talents Under the Background of "Double First-class" Construction

Shuying ZHAI, Yihe WANG, Zhaobin PEI

The construction of "double first-class" provides new opportunities and challenges for the cultivation of outstanding marine legal talents in sea-related universities. The cultivation of outstanding marine legal talents is a key link in the strategy of marine power. There are many problems in China, such as the shortage of highly educated marine legal personnel, the shortage of foreign-related marine legal personnel, the serious imbalance between the supply and demand of complex marine legal personnel, and the imperfect training mode of maritime rights protection and law enforcement personnel. Accordingly, we should adhere to the training concept of "fostering character and civic virtue", build an international and application-oriented talent curriculum system, promote the reform of teaching methods and means, promote the joint training mode of "school and bureau" and "school and local" cooperation, and strengthen the construction of excellent marine law teachers.

Oceanography
DOAJ Open Access 2023
One Hundred Priority Questions for the Development of Sustainable Food Systems in Sub-Saharan Africa

Adam J. M. Devenish, Petra Schmitter, Nugun. P. Jellason et al.

Sub-Saharan Africa is facing an expected doubling of human population and tripling of food demand over the next quarter century, posing a range of severe environmental, political, and socio-economic challenges. In some cases, key Sustainable Development Goals (SDGs) are in direct conflict, raising difficult policy and funding decisions, particularly in relation to trade-offs between food production, social inequality, and ecosystem health. In this study, we used a horizon-scanning approach to identify 100 practical or research-focused questions that, if answered, would have the greatest positive impact on addressing these trade-offs and ensuring future productivity and resilience of food-production systems across sub-Saharan Africa. Through direct canvassing of opinions, we obtained 1339 questions from 331 experts based in 55 countries. We then used online voting and participatory workshops to produce a final list of 100 questions divided into 12 thematic sections spanning topics from gender inequality to technological adoption and climate change. Using data on the background of respondents, we show that perspectives and priorities can vary, but they are largely consistent across different professional and geographical contexts. We hope these questions provide a template for establishing new research directions and prioritising funding decisions in sub-Saharan Africa.

DOAJ Open Access 2023
Antiosteoporosis medications and cardiovascular disease: a population-based nationwide nested case–control study

Wen-Hsuan Tsai, Fung-Chang Sung, Fung-Chang Sung et al.

Purpose: Patients with osteoporosis are at an increased risk of cardiovascular disease (CVD). Several antiosteoporosis medications have been demonstrated with the benefit of preventing osteoporosis. Our aim is to assess the CVD risks associated with antiosteoporosis medications using the National Health Insurance Research Database in Taiwan between 2000 and 2016.Methods: Among 41,102 patients of 40+ years old with newly diagnosed osteoporosis, 69.1% (N = 28,387) of patients were included in the user cohort of antiosteoporosis medicines, of whom 13, 472 developed CVD by the end of 2016, while 14,915 did not. Using the nested case–control analysis in the user cohort (88.0% women and 77.4% elderly), we applied conditional logistic regression to estimate odds ratios (ORs) of eight types of CVD for the users of denosumab, bisphosphonate, teriparatide, and hormone replacement therapy (HRT).Results: The adjusted ORs of overall CVDs were 0.13 (95% CI: 0.12–0.15) for denosumab users, 0.52 (95% CI: 0.45–0.61) for teriparatide users, and 0.80 (95% CI: 0.76–0.85) for bisphosphonate users. The HRT users were at higher odds of coronary artery and peripheral artery diseases, heart failure, pulmonary embolism, and deep vein thrombosis.Conclusion: Denosumab, teriparatide, and bisphosphonate may have more protective effects against CVD than hormone therapy. Physicians may take subsequent cardiovascular risks into account when choosing an adequate antiosteoporosis medication for patients with osteoporosis.

Therapeutics. Pharmacology
DOAJ Open Access 2022
Safety monitoring of COVID-19 vaccines in Japan

Toshihiro Yamaguchi, Masao Iwagami, Chieko Ishiguro et al.

Summary: The assessment of the efficacy and safety of coronavirus disease 2019 (COVID-19) vaccines in actual practice is extremely important, and monitoring efforts are being implemented worldwide. In Japan, a joint council in the Ministry of Health, Labour and Welfare is held every two to three weeks to summarise information on the adverse events following COVID-19 vaccination, with careful assessment of individual case safety reports and comparison with background incidence rates. In 2021, the joint council mainly reviewed anaphylaxis, death, myocarditis/pericarditis, and thrombosis with thrombocytopenia syndrome. These activities resulted in several safety-related regulatory actions, including the revision of vaccine package inserts with warnings about myocarditis/pericarditis. International sharing of vaccine safety information, as well as details of the evaluation systems, is important for international discussion and decision-making on better safety monitoring of COVID-19 vaccines.

Public aspects of medicine
DOAJ Open Access 2021
Evaluation of Pharmaceuticals Inventory Management in Selected Health Facilities of West Arsi Zone, Oromia, Ethiopia

Jobira T, Abuye H, Jemal A et al.

Tadesse Jobira,1 Habtamu Abuye,2 Awol Jemal,3 Tadesse Gudeta3 1Health Office Logistic Coordination, Shashemene City Administration, Shashemene, Ethiopia; 2Department of Pharmacy, College of Medicine and Health Sciences, Wachemo University, Hossaena, Ethiopia; 3Pharmaceutical Supply Chain Management Department, School of Pharmacy, Institute of Health, Jimma University, Jimma, EthiopiaCorrespondence: Habtamu AbuyeWachemo University, P.o. Box: 667, Hossaena, EthiopiaTel +251 913571974Fax +251-46-555-19-30Email harohabe@gmail.comBackground: Effective inventory management ensures an uninterrupted supply of safe, effective, and affordable pharmaceuticals which could be achieved through developing ABC-VEN (Always, Better, Control&ndash;Vital, Essential, Desirable) and FSN&ndash;XYZ (Fast, Slow, Non-moving&ndash;High, Medium, Low Value) matrix analysis. ABC&ndash;VEN matrix analysis is used to control inventory according to their annual consumption and on their functional importance whereas, FSN&ndash;XYZ matrix analysis is applied to control inventory by identifying the items to be discarded and the amount saved during the closing of annual accounts.Objective: To evaluate inventory management in selected health facilities of West Arsi zone, Oromia regional state for the year 2016&ndash; 2018.Methods: Facility-based cross-sectional descriptive study complemented with a qualitative study was conducted in fourteen health facilities. Data were collected from goods issuing vouchers for the year 2016&ndash; 2018 to perform ABC&ndash;VEN matrix analysis. The frequency of issue was collected to perform FSN analysis and the value of each closing stock was taken to get XYZ analysis.Results: From the ABC&ndash;VEN matrix analysis, 26.6% of items were Category I of which the highest proportion were taken by class A and V items consuming 84.7% of annual drug expenditure (ADE). The remaining 49.2% and 24.2% of the drugs accounted for only 13.2% and 2.1% of the ADE being category II and III, respectively. Based on FSN&ndash;XYZ matrix analysis findings, category I with 41.% item share account for the highest budget (average 86.5% of values). Of this category, the XN group&mdash;non-moving and high-cost drugs had the high value (20%) which need managerial measure. In category III, the ZN group items, being 25% of drugs, only had 2.2% of value&mdash;that may increase wastage, inventory holding cost, and shortage of storage space.Conclusion: The matrix analysis for inventory control is a strong tool that enables one to identify items requiring close monitoring. The coupled ABC&ndash;VEN matrix analysis, combining their individual advantages &ndash; inventory&rsquo;s cost and its functional importance help in achieving a meaningful inventory management. However, to control the stock at an appropriate level with minimum shortage and oversupply, it has to be supported by XYZ&ndash;FSN matrix analysis. The XYZ&ndash;FSN matrix benefits the health facilities to determine the level of inventory with high value in dead-stock, and to take measures like transferring to others, discarding, or saving.Keywords: ABC&ndash;VEN matrix analysis, FSN&ndash;XYZ matrix analysis, inventory management

Pharmacy and materia medica
DOAJ Open Access 2021
Recent genetic connectivity and clinal variation in chimpanzees

Jack D. Lester, Linda Vigilant, Paolo Gratton et al.

Lester and colleagues use faecal samples and genetic analyses to investigate the genetic connectivity across chimpanzees. Their results indicate that the global pattern of genetic diversity in chimpanzees is largely characterized by a pattern of isolation by distance with several isolated populations exhibiting strong local differentiation.

Biology (General)
DOAJ Open Access 2021
Office-Based, Point-of-Care, Low-Field MRI System to Guide Prostate Interventions: Recent Developments

Jordan Nasri, Vinayak G. Wagaskar, Sneha Parekha et al.

Abstract Prostate cancer (PCa) is the second most frequently diagnosed cancer in males; early-stage PCa is asymptomatic, and PCa has an indolent course. The current standard of care of systematic transrectal biopsy (SBx) is preferred by urologists because of its ease of use and portability, despite its shortcomings in cancer detection rate. The advent of multi-parametric MRI (mpMRI)-enabled PIRADS protocol for lesion diagnosis and characterisation has helped minimise unnecessary biopsies, supporting the active surveillance protocol of patients with low-risk PCa. The use of annotated pre-procedure MRI fused with real-time ultrasound (US) to guide biopsies has been gaining traction in clinical use, but the challenges in registration of two different modalities, gland deformation due to the probe, and significant learning curve associated with fusion have resulted in slower than expected adoption in routine clinical practice. Moreover, the fusion biopsy has only marginally improved cancer detection rate, with a complex workflow. Higher infection rate with transrectal prostate interventions has resulted in an increased use of the transperineal approach to guide biopsies and therapies. There has been significant progress made in the development of point-of-care, portable MRI systems for specific use. In this report, the authors discuss the recent developments in office-based prostate interventions that have occurred with the arrival of low-field MRI systems. The smaller footprint of the low-field system avoids the high costs associated with the installation and management of regular MRI. Additionally, the availability of transperineal MRI visible grid makes the targeting and guidance processes relatively easier with a less-steep learning curve. Since the system uses pre-plan high-field MRI acquired in the same transverse orientation as the low-field MRI, registration errors are smaller than the MRI–US registration. The use of MRI to target lesions has reduced the number of cores sampled, benefiting the patient with early clinical study showing significantly higher cancer detection rate than SBx.

Diseases of the genitourinary system. Urology
DOAJ Open Access 2021
Design Science and Co-Designing of Hybrid Workplaces

Marko Lahti, Suvi Nenonen

Background: Future places for learning and working are digitally and physically integrated hybrid environments. The archetypical context of learning is the classroom, and context of working is the office; especially in knowledge work. New information and communication technologies enable the spatial reconfiguration of work opening possibilities for work to take place across multiple locations. This paper aims to explore how the conceptual framework of design-science research in Information Systems can be applied when the design object is a hybrid working environment. Methods: The case study method as a qualitative approach was chosen; because it involves an empirical investigation of a particular contemporary phenomenon within its real life context using multiple sources of evidence. The empirical analysis of two hybrid working environments is based on Action Design Research (ADR)-entry points; where one analyzes two case studies stage by stage. By analyzing various stages in both case studies; one can identify co-designing challenges of hybrid working environments. Results: The results present four recommendations for co-designing of hybrid working environments. The use of hybrid working environment; the design of spatial solution; the identification of iterative processes; and the user experiences of presence and distance are significant. The Entry Point Analysis-tool can be used and further developed in analyzing and developing hybrid working environments. Conclusion: The results contribute to the tradition of usability studies. The usability briefing approach can be further developed by identifying the iterative processes inside the linear project management models. Additionally, design science research can find new insights from identification of the large stakeholder iterations more precisely.

Building construction
S2 Open Access 2016
Expanding the Role of Nurses to Improve Hypertension Care and Control Globally.

C. D. Himmelfarb, Y. Commodore‐Mensah, M. Hill

The role of the nurse in improving hypertension control has expanded over the past 50 years, complementing and supplementing that of the physician. Nurses' involvement began with measuring and monitoring blood pressure (BP) and patient education and has expanded to become one of the most effective strategies to improve BP control. Today the roles of nurses and nurse practitioners (NPs) in hypertension management involve all aspects of care, including (1) detection, referral, and follow up; (2) diagnostics and medication management; (3) patient education, counseling, and skill building; (4) coordination of care; (5) clinic or office management; (6) population health management; and (7) performance measurement and quality improvement. The patient-centered, multidisciplinary team is a key feature of effective care models that have been found to improve care processes and control rates. In addition to their clinical roles, nurses lead clinic and community-based research to improve the hypertension quality gap and ethnic disparities by holistically examining social, cultural, economic, and behavioral determinants of hypertension outcomes and designing culturally sensitive interventions to address these determinants.

128 sitasi en Medicine
DOAJ Open Access 2018
THE INFLUENCE OF ORGANIZATIONAL CULTURE AND WORK MOTIVATION ON EMPLOYEE PERFORMANCE OF INDUSTRIAL AND TRADE SERVICES IN AMBON CITY, INDONESIA

Riupassa E.

This study is a research on the scope of human resource management about organizational culture and motivation on employee performance of Industrial and Trade Services Office in Ambon City Maluku Province, this research includes explanatory research which aims to explain the influence of organizational culture variables (X1) and motivation variables (X2) on employee performance variables (Y). This study was conducted on 45 employees, with the sampling technique used was a census. Data collected through a questionnaire. Data analysis using multiple linear regression approach with the help of SPSS program for Windows 22. The results of the analysis concluded that simultaneously and partially the organizational culture and work motivation had a significant influence on the employees performance in Industrial and Trade Service of Ambon City; work motivation variables has a dominant influence on employee performance in Industrial and Trade Service Office of Ambon City. The results of this study recommend the importance of high work motivation and supported by organizational culture which is an important factor in the employees’ performance of Industrial and Trade Services in Ambon City.

Agriculture (General)
DOAJ Open Access 2018
Teacher Certification Programs, Teacher Motivation And School Climate On Teacher Performance (Case Study : SMK Ibnu Aqil Bogor)

Andrias Koto, Masyhudzulhak Djamil, Indupurnahayu .

<p>The purpose of this study was to effect of teacher certification programs, teacher motivation and school climate on the performance of vocational teacher Ibnu Aqil Bogor. The research was conducted at the Vocational School of Ibn Aqil Bogor sample as many as 70 teachers. The research variables are teacher certification program, gur motivation and school climate as independent variables and teacher performance as the dependent variable. Data collection using questionnaires, interviews and observations. Data were analyzed descriptively and using simple linear regression analysis.<br />The results showed the availability of teachers based on the quality of education is either minimal S1. 85.71% of teachers in vocational Ibn Aqil Bogor was educated S1. In terms of quantity of total 70 teachers filled out by the teacher labor fee of 20 people and the civil servant and teacher fixed foundation. Teacher certification programs, teacher motivation and school climate affects the quality of education by 58.2%, the remaining 41.8% is influenced by other factors.</p>

Office management, Finance
DOAJ Open Access 2017
The Odyssey of Dental Anxiety: From Prehistory to the Present. A Narrative Review

Enrico Facco, Enrico Facco, Gastone Zanette et al.

Dental anxiety (DA) can be considered as a universal phenomenon with a high prevalence worldwide; DA and pain are also the main causes for medical emergencies in the dental office, so their prevention is an essential part of patient safety and overall quality of care. Being DA and its consequences closely related to the fight-or-flight reaction, it seems reasonable to argue that the odyssey of DA began way back in the distant past, and has since probably evolved in parallel with the development of fight-or-flight reactions, implicit memory and knowledge, and ultimately consciousness. Basic emotions are related to survival functions in an inseparable psychosomatic unity that enable an immediate response to critical situations rather than generating knowledge, which is why many anxious patients are unaware of the cause of their anxiety. Archeological findings suggest that humans have been surprisingly skillful and knowledgeable since prehistory. Neanderthals used medicinal plants; and relics of dental tools bear witness to a kind of Neolithic proto-dentistry. In the two millennia BC, Egyptian and Greek physicians used both plants (such as papaver somniferum) and incubation (a forerunner of modern hypnosis, e.g., in the sleep temples dedicated to Asclepius) in the attempt to provide some form of therapy and painless surgery, whereas modern scientific medicine strongly understated the role of subjectivity and mind-body approaches until recently. DA has a wide range of causes and its management is far from being a matter of identifying the ideal sedative drug. A patient's proper management must include assessing his/her dental anxiety, ensuring good communications, and providing information (iatrosedation), effective local anesthesia, hypnosis, and/or a wise use of sedative drugs where necessary. Any weak link in this chain can cause avoidable suffering, mistrust, and emergencies, as well as having lifelong psychological consequences. Iatrosedation and hypnosis are no less relevant than drugs and should be considered as primary tools for the management of DA. Unlike pharmacological sedation, they allow to help patients cope with the dental procedure and also overcome their anxiety: achieving the latter may enable them to face future dental care autonomously, whereas pharmacological sedation can only afford a transient respite.

DOAJ Open Access 2016
Taiwan Universities: Where to Go?

Yu-Ying Kuo

The dramatic expansion of Taiwan universities/colleges from about 100 to 160 from the late 1980s has encountered problems due to social and global changes. What should Taiwan universities move toward and how? This research relies on secondary data to explore the issues Taiwan universities currently face—a low birth rate and global competition. The decreasing number of incoming students will result in a lower registration rate and less tuition revenue, which will make some universities struggle to survive. Hence, government policies, proposed by the Ministry of Education, have been implemented to assist Taiwan universities to adjust to external changes. The Innovative Transformation Policy, adopted in 2015, consists of strategies for university–industry cooperation, university mergers, university closures, and a re-shaping of the university paradigm. This policy has begun to be implemented and its initial outcome will be continually evaluated. In accordance with the Innovative Transformation Policy, this study encourages Taiwan universities to improve governance, set prominent unique characteristics of development, and enhance global competitiveness.

History of scholarship and learning. The humanities

Halaman 23 dari 656386