Hasil untuk "Manufactures"

A. Zocca, P. Colombo, C. Gomes et al.

Jay Lee, Edzel Lapira, B. Bagheri et al.

K. Wong, A. Hernandez

Additive manufacturing processes take the information from a computer-aided design (CAD) file that is later converted to a stereolithography (STL) file. In this process, the drawing made in the CAD software is approximated by triangles and sliced containing the information of each layer that is going to be printed. There is a discussion of the relevant additive manufacturing processes and their applications. The aerospace industry employs them because of the possibility of manufacturing lighter structures to reduce weight. Additive manufacturing is transforming the practice of medicine and making work easier for architects. In 2004, the Society of Manufacturing Engineers did a classification of the various technologies and there are at least four additional significant technologies in 2012. Studies are reviewed which were about the strength of products made in additive manufacturing processes. However, there is still a lot of work and research to be accomplished before additive manufacturing technologies become standard in the manufacturing industry because not every commonly used manufacturing material can be handled. The accuracy needs improvement to eliminate the necessity of a finishing process. The continuous and increasing growth experienced since the early days and the successful results up to the present time allow for optimism that additive manufacturing has a significant place in the future of manufacturing.

Yong Huang, M. Leu, J. Mazumder et al.

Mark W. Johnson, M. Amin, Gildert Suzanne et al.

T. Baines, H. Lightfoot, O. Benedettini et al.

A. Neely

S. Vachon, R. Klassen

B. Mallick

Ahmet H. Kirca, S. Jayachandran, W. O. Bearden

Fourth Edition, Averill M. Law

M. Gen, Runwei Cheng

M. Youndt, S. Snell, J. Dean et al.

J. Dunning

M. Gertler, Simon Gilchrist

I. Maskery, N. Aboulkhair, A. Aremu et al.

Abstract Lattice structures are excellent candidates for lightweight, energy absorbing applications such as personal protective equipment. In this paper we explore several important aspects of lattice design and production by metal additive manufacturing, including the choice of cell size and the application of a post-manufacture heat treatment. Key results include the characterisation of several failure modes in double gyroid lattices made of Al-Si10-Mg, the elimination of brittle fracture and low-strain failure by the application of a heat treatment, and the calculation of specific energy absorption under compressive deformation (16 × 10 6  J m −3 up to 50% strain). These results demonstrate the suitability of double gyroid lattices for energy absorbing applications, and will enable the design and manufacture of more efficient lightweight parts in the future.

Michael Schmidt, M. Merklein, D. Bourell et al.

S. Beretta, S. Romano

Xiuyan Wang, I. Rivière

The treatment of cancer patients with autologous T cells expressing a chimeric antigen receptor (CAR) is one of the most promising adoptive cellular therapy approaches. Reproducible manufacturing of high-quality, clinical-grade CAR-T cell products is a prerequisite for the wide application of this technology. Product quality needs to be built-in within every step of the manufacturing process. We summarize herein the requirements and logistics to be considered, as well as the state of the art manufacturing platforms available. CAR-T cell therapy may be on the verge of becoming standard of care for a few clinical indications. Yet, many challenges pertaining to manufacturing standardization and product characterization remain to be overcome in order to achieve broad usage and eventual commercialization of this therapeutic modality.