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DOAJ Open Access 2025
The Effect of Giving One Egg Per Day on Stunted Children Aged 2-5 Years in Buton Regency on Zinc Levels

Alvreyna Cherienda Laviashna Saputro, Dwirini Retno Gunarti

Background: Despite can be prevented with good nutrition, average prevalence of stunting in Indonesia remains high at 30.8%. The effects of stunting are detrimental to the individual and Indonesia's human resources. Stunted children had low blood zinc levels which disrupted enzyme and antioxidant activity, as well as bone growth processes and bone homeostasis. Eggs that contain zinc and have high bioavailability are expected to be able to increase low blood zinc levels. This study was designed to examine the impact of routine egg consumption on zinc levels in stunted children. Methods: This experimental quantitative study was conducted in the Siontapina Health Center, Buton Regency, Southeast Sulawesi. and included 22 participants which divided into intervention and control groups. The intervention was carried out by health workers giving one egg per day for 30 days with the same type of cooking per day to the participants. Zinc levels were assessed using a spectrophotometer and analyzed using statistical software. Result: The results showed a significant difference between the two groups (p <0.05). The average zinc level in the intervention group was 718.8133 ug/dL, which was higher than the control group (143.4536 ug/dL). Thus, giving 1 egg a day for 30 days caused a significant change in blood zinc levels in stunted children aged 2-5 years in Buton Regency. Conclusion: Stunted children supplemented with one egg daily for 30 days had significantly higher zinc levels than unsupplemented children.

Specialties of internal medicine, Pediatrics
DOAJ Open Access 2024
Potential synergistic antihyperglycemic effects of co-supplemental Amla and Olive extracts in hyperlipidemic adults with prediabetes and type 2 diabetes: results from a real-life clinical study

Hermans Michel P., Sylvie A. Ahn, Michel F. Rousseau et al.

BackgroundHyperglycemia and type 2 diabetes mellitus (T2DM) pose a significant risk for cardiovascular diseases and associated complications in individuals with hyperlipidemia. Statin therapy, effective in reducing cholesterol and cardiovascular risks, paradoxically increases incident T2DM risk due to its adverse impact on glucose homeostasis. Therefore, there is a pressing need for safe, and effective adjunctive or alternative therapies to manage hyperglycemia in hyperlipidemic individuals. There is growing body of pharmacological evidence suggesting that Amla and Olive extract supplementation can be beneficial in managing hyperglycemia in individuals with hyperlipidemia.ObjectiveThe present study aimed to assess for the first time the potential synergistic antihyperglycemic effects of a daily co-supplementation of 1,000 mg Amla fruit and 50 mg Olive fruit standardized extracts (Cholesfytol NG®) over a 2-months period in hyperlipidemic adults with T2DM or prediabetes.MethodsThis retrospective cross-sectional observational study analyzed treatment outcomes in 191 hyperlipidemic adults under the care of their physicians at 57 General Practitioner clinics in Belgium during real-life clinical practice between March 19, 2020, and January 31, 2022. These participants received Cholesfytol NG® as supplementary therapy to improve their metabolic health. The supplement was prescribed in an open-label, non-randomized manner, tailored to each participant’s need.ResultsAfter 2-months of Cholesfytol NG® supplementation, participants showed significant reductions in glycemia levels: in the T2DM group, levels decreased by 42.7 ± 17.9 mg/dL (27.9%, p &lt; 0.0001), and in the prediabetic group, by 2.26 ± 11.5 mg/dL (4.7%, p = 0.0020). Conversely, no significant change was observed in participants with normal baseline glycemia (1.55 ± 10.3 mg/dL, p = 0.088). Overall, glycemia levels decreased from 96.4 ± 18.2 mg/dL to 94.0 ± 13.5 mg/dL (mean decrease of 2.4 ± 14.5 mg/dL, p &lt; 0.0001). The supplement was well tolerated and no side-effects, serious adverse events, or treatment-emergent effects were reported.ConclusionThe findings of this real-life clinical study highlight the potential synergistic antihyperglycemic effects of co-supplementation with Amla and Olive fruit extracts in managing hyperglycemia, particularly in individuals with hyperlipidemia. These results suggest that this botanical combination may help mitigate risks associated with hyperglycemia and cardiovascular disease in hyperlipidemic population.Clinical trial registrationClinicalTrials.gov, NCT06187298.

Nutrition. Foods and food supply
DOAJ Open Access 2024
Effects of hydrocolloids and oleogel on techno-functional properties of dairy foods

Shan Zhang, Chuanying Ren, Caiyun Wang et al.

This paper aims to overview the influence of different gels that including hydrocolloids and oleogel on techno-functional changes of dairy foods. The hydrocolloids are widely added to dairy products as stabilizers, emulsifiers, and gelling agents to enhance their texture, or improve sensory properties to meet consumer needs; and the newly developed oleogel, which despite less discussed in dairy foods, this article lists its application in different dairy products. The properties of different hydrocolloids were explained in detail, meanwhile, some common hydrocolloids such as pectin, sodium alginate, carrageenan along with the interaction between gel and proteins on techno-functional properties of dairy products were mainly discussed. What’s more, the composition of oleogel and its influence on dairy foods were briefly summarized. The key issues have been revealed that the use of both hydrocolloids and oleogel has great potential to be the future trend to improve the quality of dairy foods effectively.

Nutrition. Foods and food supply, Food processing and manufacture
DOAJ Open Access 2023
An innovative method used for the identification of N-glycans on soybean allergen β-conglycinin

Cheng Li, Yang Tian, Jianli Han et al.

β-Conglycinin is one of the major allergens existed in soybean. N-Glycans attached to the β-conglycinin influenced the immunoreactivity and antigen presenting efficiency of β-conglycinin. In this study, we described a new method used to release and collect the N-glycans from β-conglycinin, and the N-glycans existed in linear epitopes of β-conglycinin were identified. Glycopeptides hydrolyzed from β-conglycinin were purified by cotton hydrophilic chromatography. Trifluoromethylsulfonic acid was then used to release glycans from glycopeptides, and new glycopeptides containing one single N-acetyl-D-glucosamine (GlcNAc) moiety were then utilized for mass spectrometry. Five glycosylation sites (Asn-199, Asn-455, Asn-215, Asn-489 and Asn-326) and 22 kinds of glycopeptides were identified. It is noteworthy that the peptide VVN#ATSNL (where # represents for the glycosylation site) was analyzed to be both glycopeptide and linear epitope. Our results provided a new method for the N-glycoform analysis of food allergens, and laid a foundation for understanding the relationship between glycosylation and food allergy.

Nutrition. Foods and food supply
DOAJ Open Access 2023
Efficacy and safety of different insulin infusion methods in the treatment of total parenteral nutrition-associated hyperglycemia: a systematic review and network meta-analysis

Lu Cao, Dan Zhang, Ying Zhao et al.

AimsTo systematically evaluate the efficacy and safety of different insulin infusion methods in the treatment of total parenteral nutrition (TPN)-associated hyperglycemia based on published literature and the data of completed clinical trials using a network meta-analysis.MethodsA comprehensive search of PubMed, Elsevier, Web of Science, EMBASE, Medline, clinicaltrials.gov, Cochrane Library, and three Chinese databases (Wanfang Data, China National Knowledge Infrastructure, and SINOMED) up to December 15, 2022, was performed to collect information on different insulin infusion methods used for the treatment of TPN-associated hyperglycemia, and the Cochrane systematic review method was used to screen the literature, evaluate the quality of the included literature, and extract clinical characteristics for a network meta-analysis. Clinical outcomes included mean blood glucose (MBG), hypoglycemia, hospital length of stay, hyperglycemia, surgical site infection (SSI) and mean total daily insulin.ResultsA total of 21 articles, including 1,459 patients, were included to analyze 6 different routes of insulin infusion, including continuous intravenous insulin infusion (CVII), continuous subcutaneous insulin infusion (CSII), subcutaneous glargine insulin (s.c. GI), the addition of regular insulin to the PN mixture (RI-in-PN), multiple subcutaneous insulin injections (MSII) and 50% of insulin administered as RI-in-PN + 50% of insulin administered as s.c. GI (50% RI-in-PN + 50% s.c. GI). The results of the network meta-analysis showed that MSII was the least effective in terms of MBG, followed by CVII. The 6 interventions were basically equivalent in terms of the hypoglycemia incidence. In terms of the length of hospital stay, patients in the CVII group had the shortest hospital stay, while the MSII group had the longest. CVII was the best intervention in reducing the incidence of hyperglycemia. The incidence of SSI was the lowest in the CSII and CVII groups, and the mean daily insulin dosage was the lowest in the CVII group.ConclusionCurrent literature shows that for the treatment of TPN-associated hyperglycemia, CVII is the most effective, reducing the incidence of hyperglycemia and shortening the length of hospital stay without increasing the incidence of hypoglycemia. MSII has the worst efficacy, leading to a higher MBG and longer hospital stay, and RI-in-PN, CSII, s.c. GI and 50% RI-in-PN + 50% s.c. GI are better in terms of efficacy and safety and can be substituted for each other. Systematic Review Registration https://www.crd.york.ac.uk/prospero/, identifier CRD42023439290.

Nutrition. Foods and food supply
DOAJ Open Access 2023
Perceptions of Probiotics and Kombucha Consumption in Relation to Emotion Regulation: An Exploratory Study Comparing Portugal and Brazil

Maria Góis, Patrícia Batista, Magnólia Araújo et al.

Probiotic products have been the focus of research for several years due to the potential of their biological properties to impact mental health, mood, and cognitive functions. Kombucha is a probiotic drink that has been reported to be beneficial for mental health, particularly at the level of emotion regulation. This study aims to understand the perception of the Portuguese and Brazilian populations regarding the consumption of probiotics and Kombucha, as well as to understand these consumers’ perceptions related to the impact on emotion regulation (and the impact of this consumption on emotion regulation). The research was conducted through an online questionnaire and had a total sample of 256 participants. The results show that there are no statistically significant differences between the consumption of probiotics and Kombucha when comparing the Portuguese and Brazilian samples. Additionally, this study reveals a significant association between probiotic consumption patterns in both the Portuguese and Brazilian samples. However, no statistically significant relationship was found between the consumption of probiotics and Kombucha and emotion regulation. This study intends to contribute to the increase in knowledge about the perception of probiotics and Kombucha consumption in relation to emotion regulation, and to draw attention to the importance of this topic in the community (society, academia, and industry).

Nutrition. Foods and food supply, Nutritional diseases. Deficiency diseases
S2 Open Access 2020
Beyond Digital

In recent years, digitisation has significantly changed the media industry. Today, digital business models are at home in almost all forms of the media. But what will come next? Will new technological developments in the field of AI or block chain, for example, have an impact? And above all: Where does media economic research go from the debate about business models? Are these developments happening so fast that we hardly have time to develop real (new) theories? This volume seeks answers to these pressing questions. The further development of media economics as an academic field will depend on whether and how this is achieved. With contributions by Harald Rau; Daniela Marzavan & Anke Trommershausen; Henriette Heidbrink; Tassilo Pellegrini & Michael Litschka; Britta M. Gossel, Andreas Will & Julian Windscheid, Christian Zabel, Sven Pagel, Verena Telkmann & Alexander Rossner; Sibylle Kunz, Sven Pagel & Svenja Hagenhoff; Jonas D. Bodenhöfer, Christopher Buschow & Carsten Winter and Jörg Müller-Lietzkow.

DOAJ Open Access 2022
Authentication of duck blood tofu binary and ternary adulterated with cow and pig blood-based gel using Fourier transform near-infrared coupled with fast chemometrics

Fangkai Han, Li Ming, Joshua H. Aheto et al.

This work aims to investigate a feasible and practical technique for the authentication of edible animal blood food (EABF) using Fourier transform near-infrared (FT-NIR) coupled with fast chemometrics. A total of 540 samples were used, including raw duck blood tofu (DBT), cow blood-based gel (CBG), pig blood-based gel (PBG), and DBT binary and ternary adulterated with CBG and PBG. The protein, fat, total sugar, and 16 kinds of amino acids were measured to validate the difference in basic organic matters among EABFs according to species. Fisher linear discriminate analysis (Fisher LDA) and extreme learning machine (ELM) were implemented comparatively to identify the adulterated EABF. To predict adulteration levels, four extreme learning machine regression (ELMR) models were constructed and optimized. Results showed that, by analyzing 27 crucial spectral variables, the ELM model provides higher accuracy of 93.89% than Fisher LDA for the independent samples. All the correlation coefficients of the optimized ELMR models’ training and prediction sets were better than 0.94, the root mean square errors were all less than 3.5%, and the residual prediction deviation and the range error ratios were all higher than 4.0 and 12.0, respectively. In conclusion, the FT-NIR paired with ELM have great potential in authenticating the EABF. This work presents amino acids content in EABFs for the first time and built tracing models for rapid authentication of DBT, which can be used to manage the EABF market, thereby preventing illegal adulteration and unfair competition.

Nutrition. Foods and food supply
DOAJ Open Access 2022
Uji Aktivitas Antioksidan dan Penetapan Kadar Flavonoid Total dan Fenolik Total Ekstrak Sidaguri (Sida rhombifolia L.)

Asma Asma, Abdul Rohman, Djoko Santosa et al.

Sidaguri atau Sida rhombifolia L. telah digunakan oleh masyarakat sebagai obat tradisional, yaitu: penghilang rasa nyeri, radang, asam urat, penyakit kuning, muntah darah, dan sakit gigi. Faktor yang mempengaruhi produksi kandungan metabolit sekunder adalah kondisi lingkungan seperti tempat tumbuh, iklim, interaksi intra dan inter-spesifik serta waktu panen. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan serta kadar flavonoid dan fenolik total ekstrak sidaguri berdasarkan tempat tumbuh. Sampel diekstraksi dengan ultrasonic-assisted extraction (UAE) dan diuji penangkapan radikal bebas menggunakan metode 2,2’-difenil-1-pikrilhidrazil (DPPH) dan 2,2’-azino-bis(3-diethyl4benzothiazoline-6-sulfonic acid) (ABTS), serta penetapan kadar flavonoid total dan kandungan fenolik total. Hasil uji aktivitas antioksidan sidaguri dari Cangkringan dan Ngemplak memiliki aktivitas antioksidan tertinggi baik pada metode penangkapan radikal DPPH dengan nilai IC50 masing-masing sebesar 0,400±0,004 dan 0,403±0,004 mg/mL, maupun metode ABTS dengan nilai TEAC masing-masing sebesar 40,733±0,240 dan 35,598±0,153 mg/g serbuk sidaguri, dengan kadar flavonoid total masing-masing sebesar 10,095±0,068 dan 12,066±0,025 mg/g serbuk sidaguri dan kadar fenolik total masing-masing sebesar 56,45±0,068 dan 31,502±0,025 mg/g serbuk sidaguri.

Pharmacy and materia medica, Nutrition. Foods and food supply
DOAJ Open Access 2022
Nanofortification of vitamin B-complex in food matrix: Need, regulations, and prospects

Shweta Rathee, Vanya Nayak, Kshitij RB Singh et al.

Micronutrient malnutrition (or hidden hunger) caused by vitamin B-complex deficiency is a significant concern in the growing population. Vitamin B-complex plays an essential role in many body functions. With the introduction of nanotechnology in the food industry, new and innovative techniques have started to develop, which holds a promising future to end malnutrition and help achieve United Nations Sustainable Developmental Goal-2 (UN SDG-2), named as zero hunger. This review highlights the need for nanofortification of vitamin B-complex in food matrix to address challenges faced by conventional fortification methods (bioavailability, controlled release, physicochemical stability, and shelf life). Further, different nanomaterials like organic, inorganic, carbon, and composites along with their applications, are discussed in detail. Among various nanomaterials, organic nanomaterials (lipid, polysaccharides, proteins, and biopolymers) were found best for fortifying vitamin B-complex in foods. Additionally, different regulatory aspects across the globe and prospects of this upcoming field are also highlighted in this review.

Nutrition. Foods and food supply
DOAJ Open Access 2022
Changes in the functions of health food in China and suggestions for the development of new functions: Comment

ZHANG Lishi

Since the regulation of health food management in China in 1996, a series of changes have taken place in the functions of health food which were allowed to apply for and approve/register in the past 26 years. The expression and interpretation of function terms/claims have been gradually improved and been more reasonable, which laid a solid foundation for further supervision and market regulation, and reserved space and possibility for the development of new health functions. This paper briefly introduced and reviewd the development and change process of the functions of health food in China, and made some suggestions for the development of new health functions.

Food processing and manufacture, Nutrition. Foods and food supply
DOAJ Open Access 2021
Effects of Post-natal Dietary Milk Fat Globule Membrane Polar Lipid Supplementation on Motor Skills, Anxiety, and Long-Term Memory in Adulthood

Sébastien Sultan, Jonas Hauser, Manuel Oliveira et al.

Early life nutrition critically impacts post-natal brain maturation and cognitive development. Post-natal dietary deficits in specific nutrients, such as lipids, minerals or vitamins are associated with brain maturation and cognitive impairments. Specifically, polar lipids (PL), such as sphingolipids and phospholipids, are important cellular membrane building blocks and are critical for brain connectivity due to their role in neurite outgrowth, synaptic formation, and myelination. In this preclinical study, we assessed the effects of a chronic supplementation with a source of PL extracted from an alpha-lactalbumin enriched whey protein containing 10% lipids from early life (post-natal day (PND) 7) to adulthood (PND 72) on adult motor skills, anxiety, and long-term memory. The motor skills were assessed using open field and rotarod test. Anxiety was assessed using elevated plus maze (EPM). Long-term object and spatial memory were assessed using novel object recognition (NOR) and Morris water maze (MWM). Our results suggest that chronic PL supplementation improved measures of spatial long-term memory accuracy and cognitive flexibility in the MWM in adulthood, with no change in general mobility, anxiety and exploratory behavior. Our results indicate memory specific functional benefits of long-term dietary PL during post-natal brain development.

Nutrition. Foods and food supply
DOAJ Open Access 2020
Perceived influence of transportation services on tourism participation among travelers in Ibadan, Oyo State, Nigeria

Kudirat Oyebisi Bakare

Tourism is one of the development strategies working to unite the world by expansion, not without transportation services, though! The study assessed the perceived influence of transportation services on tourism participation in Ibadan Metropolis, Nigeria. A structured questionnaire was used to collect information from three hundred and thirty respondents who were randomly selected from Ibadan domestic airport, one public and one private motor park, one tricycle and one motorcycle terminal, all along Ife Road through Iwo Road to Ojoo Road, and Dugbe Train Station in Ibadan. The findings revealed that the factors considered most by respondents for choice/use of transportation services were accessibility(x=4.64) ranked first; Duration of the journey (x=4.36) ranked second; and Information about the transportation services and Availability (x=4.35) both tied on third position. It was also found that a bus was the most engaged transport by travelers while the airplane was the most preferred. Availability (r = 0.211) of transportation services had a low probability of influencing tourism participation; Comfort had the likelihood of influencing transportation choice in tourism participation varied. Ride comfort showed positive significance relationship with a high marginal effect on households’ participation (r=0.539) while ambient condition and facility did not have a significant influence and had a low marginal effect (r=0.626) thus, Comfort was found to influence transportation choice towards tourism participation. Customer care had a significant influence on transportation decision of tourists on tourism participation; Safety from crime (r=0.424) and safety from accident (r=0.419) had weak correlation coefficients with participation in tourism. Meanwhile, ticketing did not have a significant coefficient but had a moderate marginal effect of 0.681. The analysis further indicated that the probability of a traveler/tourist participating in tourism increased with increase in the ticketing. Time of the journey showed significant relationship between transportation and motivation to travel. Based on the results, it was recommended that transportation services need to improve to attract interest in travel which will translate to tourism participation.

Hospitality industry. Hotels, clubs, restaurants, etc. Food service, Business
DOAJ Open Access 2020
Facilitators and barriers to condom use among Filipinos: A systematic review of literature

Ryan Q. De Torres

Background: Between 2010 and 2018, the Philippines had a 203% increase in new human immunodeficiency virus (HIV) infections. The use of condoms is an effective and practical means to prevent HIV transmission. The purpose of this study was to identify facilitators and barriers to condom use among Filipinos guided by the Ecological Model of Health Promotion. Methods: A systematic review of literature using electronic databases was performed using the following keywords: "condom," "Filipinos," and "Philippines." To be included in this review, papers should be (1) research studies, (2) studies that examined condom use, and (3) studies that sampled Filipinos residing in the Philippines. The final sample comprised of 27 articles. Results: Multiple and interrelated factors at the individual and social environment levels influence condom use among different groups of Filipinos. Majority of these factors originated at the intrapersonal level. Some of the facilitators to condom use were knowledge on HIV, higher perceived HIV risk, peer support, positive manager attitude, health provider engagement, and city ordinances. In contrast, some of the barriers to condom use were discomfort and displeasure on condom use, low parental communication, lack of sex education, social stigma, and the high price of condoms. Conclusion: A collaborative, culturally-sensitive, and population-specific approach is essential to develop and implement acceptable, sustainable, and successful condom use interventions.

Nutrition. Foods and food supply, Public aspects of medicine
DOAJ Open Access 2018
KECUKUPAN KALORI MENUNJANG PERBAIKAN IMBALANCE ELEKTROLIT PADA PASIEN DENGAN KARSINOMA BULI

Josefina Junizar, Nurpudji A Taslim , Suryani As’ad et al.

Pendahuluan Karsinoma buli merupakan jenis kanker yang dimulai di kandung kemih. Insiden karsinoma buli tahun 2000 di Amerika Serikat diperkirakan sebanyak 53.200 orang. Karsinoma buli merupakan keganasan terbanyak nomor 4 pada pria. Laporan Kasus Seorang laki-laki berusia 30 tahun dikonsul dengan diagnosa medis tumor buli-buli metastase ke hepar dan pulmo, intake inadekuat, cancer paru dan DIC. Pasien dikonsulkan karena asupan makan berkurang sejak 3 hari lalu karena merasa mengganjal di tenggorokan, nafsu makan menurun, ada rasa nyeri uluhati dan sakit perut. Asupan 24 jam 52,5 kkal. Pasien didiagnosis dengan status gizi buruk (LLA 68%), status metabolik anemia (Hb 8,9g/dl), hipoalbuminemia (albumin 3,3g/dl), hypokalemia (3,3g/dl), penurunan fungsi ginjal (ureum 64mg/dl, kreatinin 1,82mg/dl), dan status gastrointestinal fungsional. Terapi nutrisi dengan energi 1080 kkal deinaikkan bertahap sesuai toleransi pasien sampai 2700 kkal, protein 1g/kgBBI/hari dinaikkan sampai 2g/kgBBI/hari, karbohidrat 60% dan lemak 31% melalui oral awalnya kemudian pasang NGT berupa makanan lunak selanjutnya bubur saring, formula nefrisol, jus buah dan putih telur 6 butir/hari, zinc 20mg/24jam, neurodex 1tablet/24jam, KSR 600mg/24jam dan ekstrak ikan gabus 2kapsul/8jam. Setelah perawatan 18 hari, status gizi masih buruk. Kesimpulan Dukungan nutrisi yang optimal dan monitoring pada pasien kanker menunjukkan perbaikan status gizi, perbaikan status metabolik sehingga dapat mempercepat proses perbaikan keadaan umum.

Nutrition. Foods and food supply
DOAJ Open Access 2015
Uniqueness of Ethiopian traditional alcoholic beverage of plant origin, tella

Mooha Lee, Meron Regu, Semeneh Seleshe

There are many kinds of traditional fermented beverages in Ethiopia, not only of animal origin, but also of plant origin. In everyday life people enjoy fermented beverages and particularly when having guests, they like to treat them to traditional alcoholic beverages. Tella, tej, areki, borde, and shamita are drinks that each household brews to treat guests. Substrates for their production are from locally available raw materials. Therefore, the basic production method is the same, but the tastes may vary. One of the most consumed fermented alcoholic beverages is tella, which is made mostly with barley but wheat, maize, sorghum, and teff are utilized depending on the region. Its production process shows the similarity to beer: addition of malt and gesho which has the same function as hops in beer. The main fermentation yeast is Saccharomyces cerevisiae and saccharification of cereal starch seems to depend on malt. However, the degree of alcoholic fermentation is low and alcohol content varies between 2 and 6%. Lactic acid bacteria are very active in tella so pH ranges 4–5 give typical tastes such as sourness, sweetness, and bitterness. As the Ethiopian economy improves, more people drink western style beers. Tella has not been commercialized yet, so the process has not been standardized and modernized. Considering the case of Korean makgeolli and the Ethiopian creativity of utilizing gesho in tella, Ethiopia should pay more attention to tella for globalization.

Nutrition. Foods and food supply

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