ABSTRACT The complexity and rise of data in healthcare means that artificial intelligence (AI) will increasingly be applied within the field. Several types of AI are already being employed by payers and providers of care, and life sciences companies. The key categories of applications involve diagnosis and treatment recommendations, patient engagement and adherence, and administrative activities. Although there are many instances in which AI can perform healthcare tasks as well or better than humans, implementation factors will prevent large-scale automation of healthcare professional jobs for a considerable period. Ethical issues in the application of AI to healthcare are also discussed.
Daniil A. Boiko, R. MacKnight, Benjamin C Kline
et al.
Transformer-based large language models are making significant strides in various fields, such as natural language processing^ 1 – 5 , biology^ 6 , 7 , chemistry^ 8 – 10 and computer programming^ 11 , 12 . Here, we show the development and capabilities of Coscientist, an artificial intelligence system driven by GPT-4 that autonomously designs, plans and performs complex experiments by incorporating large language models empowered by tools such as internet and documentation search, code execution and experimental automation. Coscientist showcases its potential for accelerating research across six diverse tasks, including the successful reaction optimization of palladium-catalysed cross-couplings, while exhibiting advanced capabilities for (semi-)autonomous experimental design and execution. Our findings demonstrate the versatility, efficacy and explainability of artificial intelligence systems like Coscientist in advancing research. Coscientist is an artificial intelligence system driven by GPT-4 that autonomously designs, plans and performs experiments by incorporating large language models empowered by tools such as internet and documentation search, code execution and experimental automation.
For centuries, scientists have attempted to identify and document analytical laws that underlie physical phenomena in nature. Despite the prevalence of computing power, the process of finding natural laws and their corresponding equations has resisted automation. A key challenge to finding analytic relations automatically is defining algorithmically what makes a correlation in observed data important and insightful. We propose a principle for the identification of nontriviality. We demonstrated this approach by automatically searching motion-tracking data captured from various physical systems, ranging from simple harmonic oscillators to chaotic double-pendula. Without any prior knowledge about physics, kinematics, or geometry, the algorithm discovered Hamiltonians, Lagrangians, and other laws of geometric and momentum conservation. The discovery rate accelerated as laws found for simpler systems were used to bootstrap explanations for more complex systems, gradually uncovering the “alphabet” used to describe those systems.
Customer service automation has seen growing demand within digital transformation. Existing approaches either rely on modular system designs with extensive agent orchestration or employ over-simplified instruction schemas, providing limited guidance and poor generalizability. This paper introduces an orchestration-free framework using Task-Oriented Flowcharts (TOFs) to enable end-to-end automation without manual intervention. We first define the components and evaluation metrics for TOFs, then formalize a cost-efficient flowchart construction algorithm to abstract procedural knowledge from service dialogues. We emphasize local deployment of small language models and propose decentralized distillation with flowcharts to mitigate data scarcity and privacy issues in model training. Extensive experiments validate the effectiveness in various service tasks, with superior quantitative and application performance compared to strong baselines and market products. By releasing a web-based system demonstration with case studies, we aim to promote streamlined creation of future service automation.
Personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) is a novel treatment that delivers radiation in pulses of protracted intervals. Accurate prediction of gross tumor volume (GTV) changes through regression models has substantial prognostic value. This study aims to develop a multi-omics based support vector regression (SVR) model for predicting GTV change. A retrospective cohort of 39 patients with 69 brain metastases was analyzed, based on radiomics (magnetic resonance image images) and dosiomics (dose maps) features. Delta features were computed to capture relative changes between two time points. A feature selection pipeline using least absolute shrinkage and selection operator (Lasso) algorithm with weight- or frequency-based ranking criterion was implemented. SVR models with various kernels were evaluated using the coefficient of determination ( R ^2 ) and relative root mean square error (RRMSE). Five-fold cross-validation with 10 repeats was employed to mitigate the limitation of small data size. Multi-omics models that integrate radiomics, dosiomics, and their delta counterparts outperform individual-omics models. Delta-radiomic features play a critical role in enhancing prediction accuracy relative to features at single time points. The top-performing model achieves an R ^2 of 0.743 and an RRMSE of 0.022. The proposed multi-omics SVR model shows promising performance in predicting continuous change of GTV. It provides a more quantitative and personalized approach to assist patient selection and treatment adjustment in PULSAR.
This paper presents a comparative analysis of read performance for PostgreSQL and MongoDB in e-commerce scenarios, using identical datasets in a resource-constrained single-host environment. The results demonstrate that PostgreSQL executes complex analytical queries 1.6–15.1 times faster, depending on the query type and data volume. The study employed synthetic data generation with the Faker library across three stages, processing up to 300,000 products and executing each of 6 query types 15 times. Both filtering and analytical queries were tested on non-indexed data in a controlled localhost environment with PostgreSQL 17.5 and MongoDB 7.0.14, using default configurations. PostgreSQL showed 65–80% shorter execution times for multi-criteria queries, while MongoDB required approximately 33% less disk space. These findings suggest that normalized relational schemas are advantageous for transactional e-commerce systems where analytical queries dominate the workload. The results are directly applicable to small and medium e-commerce developers operating in budget-constrained, single-host deployment environments when choosing between relational and document-oriented databases for structured transactional data with read-heavy analytical workloads. A minimal indexed validation confirms that the baseline trends remain consistent under a simple indexing configuration. Future work will examine broader indexing strategies, write-intensive workloads, and distributed deployment scenarios.
This research is part of a study of a real-time, cloud-based on-street parking service using crowd-sourced in-vehicle fleet data. The service provides real-time information about available parking spots by classifying crowd-sourced detections observed via ultrasonic sensors. The goal of this research is to optimize the current parking service quality by analyzing the automation of the existing test process for ground truth tests. Therefore, methods from the field of machine learning, especially image pattern recognition, are applied to enrich the database and substitute human engineering work in major areas of the analysis process. After an introduction into the related areas of machine learning, this paper explains the methods and implementations made to achieve a high level of automation, applying convolutional neural networks. Finally, predefined metrics present the performance level achieved, showing a time reduction of human resources up to 99.58 %. The overall improvements are discussed, summarized, and followed by an outlook for future development and potential application of the analysis automation tool.
The highly non-convex optimization landscape of modern lens design necessitates extensive human expertise, resulting in inefficiency and constrained design diversity. While automated methods are desirable, existing approaches remain limited to simple tasks or produce complex lenses with suboptimal image quality. Drawing inspiration from the synaptic pruning mechanism in mammalian neural development, this study proposes OptiNeuro--a novel automated lens design framework that first generates diverse initial structures and then progressively eliminates low-performance lenses while refining remaining candidates through gradient-based optimization. By fully automating the design of complex aspheric imaging lenses, OptiNeuro demonstrates quasi-human-level performance, identifying multiple viable candidates with minimal human intervention. This advancement not only enhances the automation level and efficiency of lens design but also facilitates the exploration of previously uncharted lens architectures.
A firm can complete the tasks needed to produce output using either machines or workers. Unlike machines, workers have private information about their preferences over tasks. I study how this information asymmetry shapes the mechanism used by the firm to allocate tasks across workers and machines. I identify important qualitative differences between the mechanisms used when information frictions are large versus small. When information frictions are small, tasks are substitutes: automating one task lowers the marginal cost of other tasks and reduces the surplus generated by workers. When frictions are large, tasks can become complements: automation can raise the marginal cost of other tasks and increase the surplus generated by workers. The results extend to a setting with multiple firms competing for workers.
The integration of artificial intelligence into automated penetration testing (AutoPT) has highlighted the necessity of simulation modeling for the training of intelligent agents, due to its cost-efficiency and swift feedback capabilities. Despite the proliferation of AutoPT research, there is a recognized gap in the availability of a unified framework for simulation modeling methods. This paper presents a systematic review and synthesis of existing techniques, introducing MDCPM to categorize studies based on literature objectives, network simulation complexity, dependency of technical and tactical operations, and scenario feedback and variation. To bridge the gap in unified method for multi-dimensional and multi-level simulation modeling, dynamic environment modeling, and the scarcity of public datasets, we introduce AutoPT-Sim, a novel modeling framework that based on policy automation and encompasses the combination of all sub dimensions. AutoPT-Sim offers a comprehensive approach to modeling network environments, attackers, and defenders, transcending the constraints of static modeling and accommodating networks of diverse scales. We publicly release a generated standard network environment dataset and the code of Network Generator. By integrating publicly available datasets flexibly, support is offered for various simulation modeling levels focused on policy automation in MDCPM and the network generator help researchers output customized target network data by adjusting parameters or fine-tuning the network generator.
This paper introduces an innovative Applicant Tracking System (ATS) enhanced by a novel Robotic process automation (RPA) framework or as further referred to as MLAR. Traditional recruitment processes often encounter bottlenecks in resume screening and candidate shortlisting due to time and resource constraints. MLAR addresses these challenges employing Large Language Models (LLMs) in three distinct layers: extracting key characteristics from job postings in the first layer, parsing applicant resume to identify education, experience, skills in the second layer, and similarity matching in the third layer. These features are then matched through advanced semantic algorithms to identify the best candidates efficiently. Our approach integrates seamlessly into existing RPA pipelines, automating resume parsing, job matching, and candidate notifications. Extensive performance benchmarking shows that MLAR outperforms the leading RPA platforms, including UiPath and Automation Anywhere, in high-volume resume-processing tasks. When processing 2,400 resumes, MLAR achieved an average processing time of 5.4 seconds per resume, reducing processing time by approximately 16.9% compared to Automation Anywhere and 17.1% compared to UiPath. These results highlight the potential of MLAR to transform recruitment workflows by providing an efficient, accurate, and scalable solution tailored to modern hiring needs.
Large Language Models (LLMs) have gained prominence in domains including cloud security and forensics. Yet cloud forensic investigations still rely on manual analysis, making them time-consuming and error-prone. LLMs can mimic human reasoning, offering a pathway to automating cloud log analysis. To address this, we introduce the Cloud Investigation Automation Framework (CIAF), an ontology-driven framework that systematically investigates cloud forensic logs while improving efficiency and accuracy. CIAF standardizes user inputs through semantic validation, eliminating ambiguity and ensuring consistency in log interpretation. This not only enhances data quality but also provides investigators with reliable, standardized information for decision-making. To evaluate security and performance, we analyzed Microsoft Azure logs containing ransomware-related events. By simulating attacks and assessing CIAF's impact, results showed significant improvement in ransomware detection, achieving precision, recall, and F1 scores of 93 percent. CIAF's modular, adaptable design extends beyond ransomware, making it a robust solution for diverse cyberattacks. By laying the foundation for standardized forensic methodologies and informing future AI-driven automation, this work underscores the role of deterministic prompt engineering and ontology-based validation in enhancing cloud forensic investigations. These advancements improve cloud security while paving the way for efficient, automated forensic workflows.
Integrated Hydrogen–Energy Systems (IHES) have attracted widespread attention; however, distributed energy sources such as photovoltaics (PV) and wind turbines (WT) within these systems exhibit significant uncertainty and intermittency, posing key challenges to scheduling complexity and system instability. As a core mechanism for the integrated operation of IHES, electricity price regulation can promote the absorption of renewable energy, optimize resource allocation, and enhance operational economy. Nevertheless, uncertainties in IHES hinder the formulation of accurate electricity prices, which easily lead to delays in scheduling responses and an increase in cumulative operating costs. To address these issues, this study develops lifespan models for Proton Exchange Membrane Electrolyzers (PEMELs) and Proton Exchange Membrane Fuel Cells (PEMFCs), constructs dynamic equations for the demand side and response side, and proposes a fuzzy-weighted dynamic pricing strategy. Simulation results show that, compared with fixed pricing, the proposed dynamic pricing strategy reduces economic indicators by an average of 15.3%, effectively alleviates energy imbalance, and optimizes the energy supply of components. Additionally, it reduces the lifespan degradation of PEMELs by 21.59% and increases the utilization rate of PEMFCs by 54.8%.
Liudmyla Parasiuk, Serhii Illiash, Tetiana Stasiuk
et al.
Introduction. The article considers the features of calculating fuel consumption rates for machines and mechanisms. The main methods for determining fuel rates are analyzed, the influence of technical, operational and external factors is taken into account, and the environmental component is considered, in particular, the impact of fuel consumption on the environment and the use of SCR systems to reduce harmful emissions.
The rational use of fuel and energy resources is one of the key tasks in the field of operation of vehicles and road construction equipment. An important role in this process is played by modern methods of assessing fuel consumption and the use of selective catalytic neutralization (SCR) systems, which allow reducing harmful emissions. To achieve maximum fuel efficiency, it is necessary to take into account a wide range of factors that affect the operation of equipment.
Issues. Calculating fuel consumption rates is a complex process due to the variety of factors that influence it. The main problems facing researchers and engineers are the great variability of equipment operating conditions (terrain relief, climatic conditions, soil type, etc.), the dependence of fuel consumption on the technical condition of machines, the control method and the level of process automation, the lack of a universal methodology that takes into account all aspects of the operation of different types of equipment, the need to develop effective algorithms for optimizing fuel consumption.
Purpose. The purpose of the study is to analyze modern approaches to calculating fuel consumption rates, identify key factors affecting fuel consumption, and develop recommendations for optimizing the use of fuel resources in mechanical engineering and the transport sector.
Materials and methods. The article is of a review nature. The article uses a systematic approach, which is a set of general scientific methodological principles (requirements), based on the consideration of objects as systems.