Impact of Drilling Speed and Osteotomy Technique (Primary Bone Healing) on Dental Implant Preparation: An In Vitro Study Using Polyurethane Foam
Luca Comuzzi, Margherita Tumedei, Tea Romasco
et al.
<b>Background/Objectives</b>: The achievement of primary stability in low-density bone represents a critical endpoint in clinical practice. The aim of the present investigation was to evaluate the effectiveness of different drilling osteotomy techniques on polyurethane bone substitutes in vitro. <b>Methods</b>: A total of 320 osteotomies have been conducted on 10 pound per cubic feet (PCF) and 20PCF, respectively, with and without cortical layer. The simultaneous and progressive drilling protocol has been conducted at two different rotational speeds considering two different implant profiles (TAC conical vs. NT cylindrical implants). The study variables were insertion torque, removal torque, and resonance frequency analysis (RFA). <b>Results</b>: A significantly higher insertion torque, removal torque, and resonance frequency analysis RFA was detected at low speed with simultaneous drilling protocol (RPM) (<i>p</i> < 0.05). A TAC implant produced an increased implant stability compared to NT implants in all conditions tested (<i>p</i> < 0.05). <b>Conclusions</b>: The conical TAC implant showed higher implant stability in low-density polyurethane, and it is strongly recommended in critical bone quality. Simultaneous drilling osteotomy at low speed could further improve torquing positioning and significantly achieve primary stability in this condition.
Sixty Years of Innovation in Biomechanical Orthognathic Surgery: The State of the Art and Future Directions
Carlos Aurelio Andreucci
Craniofacial surgery is proposed and performed for a variety of reasons, ranging from congenital or acquired malformations to emotional disorders and parafunctions of the masticatory, respiratory, auditory, and visual systems. Surgery of the mandible and its orthostatic repositioning is the most common of these corrections of craniofacial anomalies. Throughout the history of these procedures, various techniques have been proposed and perfected, but always with a high rate of minor and major complications. The recurrence rate of mandibular malposition is high, as is the temporary loss of facial sensitivity and motor skills. These outcomes are often related to the choice of surgical technique rather than the skill of the surgeon, which is considered to be one of the most important factors in the final outcome. Surgical techniques involving direct manipulation of the vascular-nervous bundles, such as bilateral sagittal split osteotomy, clearly present the possibility of major or minor complications. In this study, an orthognathic surgical technique, performed by the same team for over 40 years and now available through a 20-year postoperative patient follow-up study, is presented with a literature review relating it to biomechanical concepts and bone remodeling to analyze the evolution of orthognathic surgery since it became common practice to correct maxillofacial discrepancies. In this review, we also present a case report in which previous orthodontic treatment prepared a patient for surgical correction of mandibular bone discrepancy without the need for combined maxillary and/or genioplasty, and we describe the most commonly used techniques today, as well as their advantages and disadvantages. The combination of established concepts together promotes favorable stability of mandibular osteotomies, functional anatomical positioning of the temporomandibular joint, reduced risk of injury to the mandibular vasculo-nervous bundle, and good aesthetics with positive patient acceptance and no relapse, thus these are the objectives for proposing innovative treatments that combine the technologies available today.
Paleoanthropological Analysis of Osteological Material from the Myntobe Burial Ground
Gursoy M. , Baitanayev Bauyrzhan A., Acar Emel
et al.
The article deals with the paleoanthropological analysis of the skeletons unearthed from the Myntobe necropolis and dated to the II – IV centuries AD. Myntobe necropolis is located 2 km south of Gani Muratbayev village in the Keles district of Turkestan province. The burial ground consists of more than 600 randomly located mounds of various sizes. All mounds have a dirt embankment. Archaeological excavations were carried out at the burial ground in 2017 and 2022, as a result of which burials in the catacombs and naus were unearthed. An analysis of the burial tradition and recovered material allows researchers to speak about the belonging of these burials to the Kangli tribes. Since the burials date back to the Kangli period, the theoretical part reveals the issues of the location and political structure of the tribes and, most importantly, the determination of the paleopathology of the Myntobints by conducting a macroscopic analysis of the discovered skeletons. The results of the analysis allowed for drawing preliminary conclusions about lifestyle, social life, and nutritional status. When writing the theoretical part of the article, electronic textbooks and resources from the book fund of the National Library of Kazakhstan and the library of the International Kazakh-Turkish University named after Kozh Ahmet Yasawi were used. In total, 9 skeletons were selected for paleoanthropological and paleopathological analysis, from mounds No. 3, No. 6, and No. 7. Paleoanthropological reasoning in the main section is written on the basis of materials in Turkish and English from the collections of Turkish libraries. The skeletons found were analyzed macroscopically and many diseases were identified, such as osteoarthritis (joint deformity), osteopathy, ankylosing spondylitis, heel spurs, thickening of the cranial bone, and deformity of the mandibular joint. Preliminary conclusions about the paleopathology of the discovered skeletons are made.
Effect of manual osteopathic techniques on the autonomic nervous system, respiratory system function and head-cervical-shoulder complex—a systematic review
Jakub Stępnik, Jakub Stępnik, Dariusz Czaprowski
et al.
BackgroundOsteopathic manual techniques are now widely used in medicine worldwide. At present, there are no clear conclusions regarding the possibility of affecting the function of the autonomic nervous system (ANS), respiratory system and head-cervical-shoulder complex by manual osteopathic techniques.ObjectivesThe aim of the study was to review the current literature regarding the possible impact of osteopathic manual techniques on the state of the autonomic nervous system, spirometric parameters of the respiratory system and the state of the head-collar-shoulder complex.MethodsPublications have been searched in the following databases: PubMed, Virtual Health Library and Cochrane Central Register of Controlled Trials. The search strategy included keywords related to manual osteopathic treatment, autonomic nervous system, spirometry, respiratory function and head, neck and shoulder pain. The methodological quality of the included studies was assessed. The PRISMA guidelines were used for the systematic review. Studies from 2010 to 2023 were selected.ResultsUsing the proposed descriptions and manual searches from the literature of other works, 40 studies were found, out of which 22 were rejected because they did not meet the inclusion criteria. The analysis included: 15 randomized controlled trials, 3 pilot studies.ConclusionStudies clearly show the effect of OMT on both spirometric parameters and the condition of the head-collar-shoulder complex. Most often this translates into improved ANS performance, but there are exceptions.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, CRD42023476963.
Single-Lateral-Incision Technique for Talar Neck Fractures—A Viable Option
Paul M. Ryan, Jacob Arthur, Keanu McMurray
et al.
Background: Displaced talar neck fractures are subject to avascular necrosis and degenerative joint disease. A single-lateral-incision approach may avoid damage to the remaining blood supply to the talar body provided by the deltoid artery. The purpose of this paper is to describe the surgical technique for a single approach to talar neck fractures, to evaluate the outcomes in a cohort of patients, and to review the literature on the topic. Method: A retrospective review. Patients were identified at a single medical center and met the following inclusion criteria: closed fracture, type-II talar neck fracture with displacement of the subtalar joint, single lateral operative approach, and radiographic follow-up of at least 6 months. Results: Five patients were identified meeting the inclusion criteria. The mean follow-up was 18 months (12–25). The mean VAS (Visual Analog Score) score at the final follow-up was 1.2 (0–3). Four of five patients returned to running at the final follow-up. The one patient who did not return to running was able to bike and hike. There were no cases of avascular necrosis and no cases of degenerative joint disease. Conclusions: Although a two-incision approach could be considered for all displaced talar neck fractures, there are certain fractures that can be anatomically reduced and stabilized through a single lateral incision which may limit the risk of avascular necrosis.
Paget's disease of bone presenting with multiple cranial nerve palsies: A case report
M. Hamid, MD, F. Touarsa, MD, A. Satte, MD
et al.
Paget's disease of bone (PDB) is a progressive monostotic or polyostotic osteopathy with unknown cause. It is associated with the involvement of the nervous system. The cranial nerves, spinal roots, cauda equina, spinal cord, and brain can be affected in PDB due to their close anatomical relation to bone. Hearing loss occurs in 12%-50% of patients with PDB. The optic nerve can be affected at the optic canal. The diagnosis of PDB is radiological by highlighting characteristic lesions like thickening of the cortical bone, hypertrophic and fibrillary bones. Progressive or chronic neurological deficits should be treated with bisphosphonates. We present a rare case of multiple cranial nerve palsies as the first manifestation of PDB.
Medical physics. Medical radiology. Nuclear medicine
An Active Inference Account of Touch and Verbal Communication in Therapy
Joohan Kim, Jorge E. Esteves, Jorge E. Esteves
et al.
This paper offers theoretical explanations for why “guided touch” or manual touch with verbal communication can be an effective way of treating the body (e.g., chronic pain) and the mind (e.g., emotional disorders). The active inference theory suggests that chronic pain and emotional disorders can be attributed to distorted and exaggerated patterns of interoceptive and proprioceptive inference. We propose that the nature of active inference is abductive. As such, to rectify aberrant active inference processes, we should change the “Rule” of abduction, or the “prior beliefs” entailed by a patient’s generative model. This means pre-existing generative models should be replaced with new models. To facilitate such replacement—or updating—the present treatment proposes that we should weaken prior beliefs, especially the one at the top level of hierarchical generative models, thereby altering the sense of agency, and redeploying attention. Then, a new prior belief can be installed through inner communication along with manual touch. The present paper proposes several hypotheses for possible experimental studies. If touch with verbal guidance is proven to be effective, this would demonstrate the relevance of active inference and the implicit prediction model at a behavioral level. Furthermore, it would open new possibilities of employing inner communication interventions, including self-talk training, for a wide range of psychological and physical therapies.
Osteopathy in the Cranial Field as a Method to Enhance Brain Injury Recovery: A Preliminary Study
Michelle Dickerson, Susan Murphy, Natalie Hyppolite
et al.
The clinical burden of traumatic brain injury (TBI) continues to grow worldwide, with patients often developing chronic neurological, behavorial, and cognitive deficits. Treatment and management strategies remain a key challenge, given that they target the symptoms and not the underlying pathological response. To advance pre-clinical research and therapeutic developments, there is a need to study treatment strategies that improve brain injury recovery. Cranial osteopathic manipulative medicine (cOMM) is a non-invasive and non-pharmacological strategy that has been shown to improve quality of life for several medical conditions and injuries, and may be able to treat TBI and reduce subsequent symptoms. In this study, we aimed to evaluate the neurobiological effect of cOMM on the injury response and its potential to alleviate symptoms. We investigated the ability of cOMM to enhance fluid transport by quantifying fluorescent tracer clearance throughout the brain. Further, using an in vivo TBI model, male rats were exposed to a repeated blast overpressure that was followed by cOMM treatment 24?h later. Our findings indicated that cOMM treatment attenuated acute and subacute anxiety-like behaviors. Post-mortem pathological examination in the hippocampus, pre-frontal, and motor cortices indicated improvements in glial pathology in cOMM-treated animals compared to the untreated injury group. Overall, this is the first study to explore cOMM as a treatment option for brain injury, demonstrating its capability to improve TBI outcomes.
Medical emergencies. Critical care. Intensive care. First aid
Visceral Manipulation in Resources of Persian Medicine
Parva Namiranian, Mehrdad Karimi, Seyede Zahra Emami Razavi
et al.
Persian Medicine applies various types of treatment, from changing lifestyle (known as Setteh-e-zarurieh) to using medicines and manual interventions. Manual interventions have various types and indications in Persian Medicine. Visceral manipulation is one of them, which is defined as applying techniques to the viscera or the structures that support it in the case of disturbed motility or mobility related to a visceral system and the associated elements. Herein, Persian Medicine manuscripts were searched to find available information about visceral manipulation. There are many similarities between basic principles of visceral manipulation and Persian Medicine. Persian Medicine scholars have explained about anatomy of fascia and its components many years ago, which are very close to what today’s knowledge is. Most probably, one of the very first scholars who has mentioned the idea of visceral manipulation is Avicenna (980–1037 CE). In his Canon of Medicine, Avicenna mentioned Ghamz as a treatment for liver injury. The available in vitro and animal studies support the positive effects of visceral manipulation. Persian Medicine scholars had detected nerve fibers and collagen which are fascia components. They are pioneer in this regard, too.
Public aspects of medicine
The use of Plan-Do-Study-Act (PDSA) cycle in perfection of fracture liaison service work
Ksenia Y. Belova, Olga B. Ershova
Background: Secondary fracture prevention services (FLS) have been established around the world during several last years. However, due to the differences of medical care organization in different regions, it is difficult to offer a unified approach of the structure and separate components of such services, which could be used everywhere. It is recommended to apply the Plan-Do-Study-Act (PDSA) cycle to evaluate the FLS in the institution.
Aim: To study the application of the PDSA cycle in the optimization of FLS working in Yaroslavl.
Materials and methods: We evaluated the effectiveness of FLS organization which was created in the Emergency medical care hospital n.a. N. V. Solovyov at two stages of its development: at the first stage we worked using the principle by referral of a traumatologist, at the second stage we used a dedicated coordinator. We used the questionnaire Best Practice framework for assessment. We also used PDSA cycle to analyze and evaluate the effectiveness of FLS organization.
Results: At the stage by referral of a traumatologist we revealed problems with patients identification, timing of assessment after a fracture, low frequency of initiation of osteoporosis therapy, lack of a falls prevention system and problems with a database. After the analysis and revealing shortcomings weve made several changes in the organization of our FLS. First of all we introduced a dedicated coordinator-nurse in the staff of FLS.The following analysis showed that significant improvements had been made in all revealed directions. The following application of the PDSA cycle again identified several issues of FLS organization requiring improvement.
Conclusion: Thus, the use of the PDSA cycle during the organization of FLS is a tool of effective control and establishment of an effective care system for patients with low-energy fractures.
Displasia fibrosa simulando metástasis costal
García-Gómez FJ, de la Riva-Pérez PA, Calvo-Morón MC
Factors influencing bone mineral density in postpartum women
Tatiana V. Novikova, Lubov V. Kuznetsova, Natalia Yu. Yakovleva
et al.
Background: Osteopenia is a common condition. Therefore, identification of groups for prevention of osteoporosis and restoration of bone mineral density (BMD) remains relevant.
Aim: to assess the factors contributing to development of osteopenia in puerperas.
Methods: prospective cross-sectional study. We examined 112 patients aged 20-35, 3-5 days after delivery. To assess possible factors for BMD decrease, we analyzed medical history, lifestyle, nutrition, anthropometric data, obstetric and gynecological history, and pregnancy course. We also assessed serum levels of 25-hydroxycalciferol (25-OH-D) and PTH. BMD was measured by dual energy x-ray osteodensitometry. We considered Z-score from -1 to -2.5SD as osteopenia, below -2.5 SD-as osteoporosis.
Results: based on Z-score values, two groups were formed: 1 (n=70) - puerperas with osteopenia, 2 (n=42) - puerperas with normal BMD. In the first group, osteopenia in the distal radius was observed in 48%, in the lumbar spine in 16% and in the proximal femur in 36%. Influence of the following possible factors in group 1 was established: BMI in 15-20 years 18 kg/m2 (p0.013), BMI 25 kg/m2 (p0.018), 25-OH-D less than 25 ng / ml (p 0.0018), calcium intake less than 800 mg/day (p0.041). Menstrual disorders (p0.052) and preeclapsia (p 0.042) affected lumbar spine BMD. In group 1, vitamin D deficiency was detected in 82% of women, 18% showed vitamin D insufficiency; in group 2, vitamin D deficiency was found in 16%, deficiency in 70%, in 14% vitamin D was normal. In women with a combination of factors such as BMI 18 kg/m; calcium intake lower than 800 mg/day, menstrual cycle disorders, vitamin D deficiency - osteopenia in the distal radius occured 11 times more often (OR=11,47059; CI 95%=[4,0326; 32,627]).
Conclusion: most significant impact on BMD decrease in puerperas can be expected if patient has the following risk factors: BMI18 kg/m2; 25-OH- D25 ng/ml ; nutrition with calcium intake 800 mg per day, preeclampsia. Combination of these factors may increase the risk of osteopenia in the distal radius.
Influencia de la vitamina D sobre la microestructura y propiedades biomecánicas de pacientes con fractura de cadera
Montoya MJ, Vázquez MA, Miranda C
et al.
Introducción: Valorar niveles séricos de 25-hidroxivitamina D -25(OH)D-, hormonas con influencia sobre el metabolismo óseo (parathormona -PTH- y factor de crecimiento insulínico -IGF-I-), marcadores de remodelado óseo (MRO) (telopéptido carboxilo-terminal del colágeno tipo I -?-CTX- y propéptido aminoterminal del procolágeno tipo I -PINP-), densidad mineral ósea (DMO), microestructura y biomecánica de cuello de fémur, en pacientes con fractura de cadera osteoporótica (OP) vs. pacientes artrósicos (OA). Material y métodos: Estudio observacional transversal de 29 pacientes OP y 14 OA, edad ?50 años. Cuantificamos niveles séricos hormonales y MRO (inmunoensayo), DMO de cadera (DXA), microestructura (micro-CT) y biomecánica (ensayos de compresión uniaxial, sistema IGFA). Análisis estadístico (SPSS 20.0.) Resultados: Los pacientes OP presentaron niveles inferiores de 25(OH)D (p=0,02) y DMO de cadera (p<0,05), y superiores de PTH (p=0,029) y de ?-CTX (p=0,04). Los niveles de 25(OH)D se correlacionaron positivamente con IGF-I (p=0,04) y negativamente con ?-CTX (p=0,003). Los valores de PTH se correlacionaron negativamente con DMO de cadera (p=0,0005) y positivamente con la separación trabecular (Tb.Th) (p=0,006). Los pacientes con niveles de 25(OH)D <20 ng/mL presentaron niveles mayores de ?-CTX (p=0,006), menores de IGF-I (p=0,007) y Tb.Th (p=0,04). Conclusiones: Los niveles de vitamina D son bajos en población anciana, sobre todo en pacientes con fractura de cadera osteoporótica. Además, en estos pacientes existen niveles elevados de PTH y MRO y descendidos de DMO. Los pacientes cuyos niveles de 25(OH)D son inferiores a 20 ng/mL presentan un remodelado óseo más elevado, con menores niveles de IGF-I y alteraciones de la estructura ósea (Tb.Th) que puedan estar en relación con un mayor riesgo de fracturas.
La calculadora Garvan y el riesgo de fractura por fragilidad
Hernández Hernández JL, Olmos Martínez JM
Deficiencia de vitamina D en España. ¿Realidad o mito?
Navarro Valverde C, Quesada Gómez JM
SODERZhANIE VITAMINA D 3 I POKAZATELI METABOLIZMA KOSTNOY TKANI U MUZhChIN S SAKhARNYM DIABETOM 2 TIPA
A F VERBOVOY, L A ShARONOVA, N I VERBOVAYa
et al.
Prevención interdisciplinar de la fractura de cadera
Mesa Ramos M
Diabetes mellitus tipo 2 y osteoporosis
García-Martín A, Muñoz-Torres M
The journal 'chiropractic & osteopathy' changes its title to 'chiropractic & manual therapies'. a new name, a new era
Walker Bruce F, French Simon D, Cameron Melanie
et al.
<p>Abstract</p> <p><it>Chiropractic & Osteopathy </it>changes its title to <it>Chiropractic & Manual Therapies </it>in January 2011. This change reflects the expanding base of submissions from clinical scientists interested in the discipline of manual therapy. It is also in accord with the findings of a review of the journal content and a joint venture between the original parent organisation the Chiropractic and Osteopathic College of Australasia and a new partner the European Academy of Chiropractic, which is a subsidiary body of the European Chiropractors' Union. The title change should encourage submissions from all professionals interested in manual therapy including chiropractors, osteopaths, physiotherapists, medical doctors and scientists interested in this field.</p>
Chiropractic, Diseases of the musculoskeletal system
Efecto del ácido zoledrónico sobre los marcadores del remodelado óseo en la enfermedad de Paget
Díaz Curiel M, Serrano Morales R, De la Piedra Gordo C
et al.
Antecedentes: La llegada de los bisfosfonatos significó un adelanto en el tratamiento de la enfermedad ósea de Paget (EOP), pero se necesitan agentes más eficaces y de uso más cómodo para aumentar el cumplimiento terapéutico. El ácido zoledrónico, un bisfosfonato administrado en forma de una única perfusión intravenosa, podría satisfacer estas necesidades.
Método: Hemos administrado una perfusión de 15 minutos de duración de 5 mg de ácido zoledrónico a pacientes con EOP. El criterio principal de valoración de la eficacia fue la tasa de respuesta terapéutica a los 6 y a los 12 meses, definida como una normalización de los niveles de fosfatasa alcalina (FA), de propéptido aminoterminal del procolágeno tipo 1 (P1NP), como marcadores de formación y de telopéptido carboxi-terminal del colágeno tipo 1 (CTx) como marcador de resorción. Hemos valorado asimismo la respuesta de la FA, CTx y P1NP a los 18 y 24 meses.
Resultados: A los 6 meses y 12 meses, todos los pacientes que recibieron ácido zoledrónico presentaron una respuesta terapéutica con normalización de las cifras de FA, P1NP y CTx. La respuesta se mantuvo a los 18 y 24 meses aunque solo 1 paciente mostró elevación de la FA a los 24 meses coincidiendo con elevación de la gamma-glutamiltranspeptidasa hepática.
Conclusiones: Una perfusión única de ácido zoledrónico produce una respuesta rápida, completa y sostenida en la EOP.