Quantum computers generally need to operate under more regulated physical condition than classical computer because of quantum mechanics. Classical computer uses bits and quantum computer use qubits. According to IBM, “Groups of quits in superposition can create complex, multidimensional computational spaces” that enable more complex calculations. Quantum algorithms like Shor’s and Grover’s run significantly faster than various algorithms for classical computer. Quantum entanglement offers fascinating opportunities for enhancing AI algorithms through improved computational efficiency. But practical implementation remains challenging due to technical limitations and the need for further research in the field of quantum machine learning. This article provides a brief overview of different quantum computing methods.
Nivash R., S. Srinidhi, Jayendra N. Bandyopadhyay
et al.
We investigate the dynamical behavior of a topological superconducting system, demonstrating that its static configuration undergoes a transition driven by an intrinsic supercurrent. By analyzing the band population, we confirm the quasiparticle nature of the system both in the presence and absence of an external laser field. Under laser driving, we observe an enhancement in static emission forming a plateau-like structure, accompanied by multiple coherent transitions in the population. These transitions exhibit Rabi-like oscillations, attributed to the presence of Majorana bound states (MBS), further reinforcing the quasiparticle character of the model. Our results highlight the efficacy of laser driving as a probe of the system's topological and dynamical stability.
Abstract There is a wall today in plant operations, maintenance, and reliability, where the integrity of assets is of critical importance to the health, safety, environmental and financial performance of plant operations. In many cases, the integrity of assets is only partially known, is informed by overly conservative assumptions or follows rules that have been established as part of historical approaches. The mechanical health of critical pressure vessels, piping and other assets is limited by the fidelity and model size of its finite element simulation. Operators must choose between speed, accuracy, and quality in setting up an asset health integrity system and legacy approaches provide partial answers at best and/or workflows that are not well suited for asset health integrity systems. Industry has relied on finite element analysis to determine structural integrity during design, but new advances in numerical reduction methods and computational advances have been combined to dramatically decrease the time needed to solve high fidelity whole-asset structural simulations to visualize stress fields, accumulated fatigue life, and other structural/mechanical analysis in real-time. This paper will address this problem through the lens of two real-world pressure vessels, demonstrate the limitations of legacy approaches, and discuss the benefits of running structural simulations in real time.
In Gaussian approximation, we investigate the marginal electromagnetic fluctuation in models of charged relativistic bosonic superfluids in three and two spatial dimensions at zero temperature. The electromagnetism is modeled by the ordinary Maxwell term and the non-local pseudo-electrodynamics action in these dimensions respectively. We explore the collective excitations in these systems by integrating the superfluid velocity fields. In (3+1) dimensions, we derive the roton mode reminiscent of what was discovered in the context of the free relativistic Bose-Einstein condensate as a generalization of the Higgs mode and determine the necessary and sufficient condition for the roton to exist. In (2+1) dimensions, besides solving the dispersion relation for the surface plasmon, we prove there cannot be roton-like excitation in this model as opposed to its (3+1) dimensional counterpart, and additionally derive the asymptotic lines of the dispersion in the limits of long wavelength and short distance.
Cobalt phosphate (Co3(PO4)2) has been recognized as a biomimetic superoxide anion (O2•–) sensing material, but there is a great challenge to achieve high sensitivity due to its relatively poor cond...
Evidence from pain research shows that the effectiveness of active pharmacological treatments can be enhanced by placebo effects. The “open drug administration” is superior to "hidden drug administration." In a randomized controlled trial, we aimed to show that the targeted use of placebo effects increases the efficacy of an antihistamine (dimetindene) infusion in participants with atopic dermatitis. We openly infused dimetindene (drug) in full sight with information (intervention group 1: OPEN‐DRUG+INST), openly infused drug with an additional classical conditioning learning experience (intervention group 2: OPEN‐DRUG+INST+COND) or infused drug without any information or sight (i.e., hidden administration (control group 1: HIDDEN‐DRUG)). Control group 2 received a placebo infusion (saline) declared as dimetindene and also experienced the conditioning experience (PLAC+INST+COND). Itch was experimentally induced with histamine via a skin prick test. Outcome was assessed at the subjective (primary end point: experimental itch intensity, numeric rating scale), and objective level (secondary end point: wheal size, mm2). Experimental‐induced itch intensity decreased in all groups but at different rates (P < 0.001). The groups with the open administration, whether it was dimetindene or placebo, had significantly stronger reductions in itch compared to the HIDDEN‐DRUG group (OPEN‐DRUG+INST+COND: P < 0.001; OPEN‐DRUG+INST: P = 0.009; and PLAC+INST+COND: P < 0.001). Additional drug conditioning mediated via expectation led to a stronger reduction of itching (P = 0.001). Results on wheal size were similar (P = 0.048), however, no significant difference between the HIDDEN‐DRUG group and the PLAC+INST+COND group (P = 0.967) was found. We conclude that specifically generated targeted placebo effects can significantly increase the action of a drug (dimetindene) and should be used in clinical practice.
Supplemental Digital Content is Available in the Text. Abstract Allard, P, Martinez, R, Deguire, S, and Tremblay, J. In-season session training load relative to match load in professional ice hockey. J Strength Cond Res 36(2): 486–492, 2022—The aim of this study was to describe match load and intensity across player positions and match periods, the distribution of pregame training load and intensity over training days before a match, by player position, and the cumulative weekly training load over a season. Fifty professional ice hockey players, which at one time or another were part of the roster for the Laval Rocket during the 2017-18 season of the American Hockey League, participated in this study. External load was monitored in every training session and match over the season using portable inertial measurement units. Data are reported in absolute and relative values to a match. Defensemen have a lower intensity during matches than forwards (−1.70 OIL·min−1) while load is similar across position. The first period shows a higher relative load (+5.28% relative on-ice load [OIL]) while the third has a lower relative intensity (−2.91% OIL·min−1). Defensemen seem to train at a systematic higher relative intensity than wingers and centers (+8.34% relative OIL·min−1). Finally, the weekly training load remains relatively constant throughout the season (equivalent of 3.56 ± 1.69 matches played per week). Our results support the need for player monitoring in ice hockey using an individualized approach.
A poly(phenylene sulfide) (PPS) catalytic membrane (PPSCM) was prepared through a heterogeneous sulfonation of PPS nonwoven fabrics with sulfur trioxide (SO3) as a sulfonation agent under mild cond...
Lucas Brandão, Vitor de Salles Painelli, T. Lasevicius
et al.
Brandão, L, de Salles Painelli, V, Lasevicius, T, Silva-Batista, C, Brendon, H, Schoenfeld, BJ, Aihara, AY, Cardoso, FN, de Almeida Peres, B, and Teixeira, EL. Varying the order of combinations of single- and multi-joint exercises differentially affects resistance training adaptations. J Strength Cond Res XX(X): 000-000, 2020-Our study aimed to compare the effects of multi-joint (MJ) and single-joint (SJ) exercises, either isolated or in combination, and in different orders, on cross-sectional area (CSA) of the pectoralis major (PM) and different heads of the triceps brachii (TB), as well as on the one-repetition maximum (1-RM) in the bench press and lying barbell triceps press. Forty-three young men were randomly assigned to one of 4 possible RT protocols: barbell bench press plus lying barbell triceps press (MJ + SJ, n = 12); lying barbell triceps press plus barbell bench press (SJ + MJ, n = 10); barbell bench press (MJ, n = 10); or lying barbell triceps press (SJ, n = 11). Results showed significant within-group increases in 1-RM bench press for MJ, MJ + SJ, and SJ + MJ but not for SJ. Conversely, significantly greater within-group increases in elbow extension 1-RM were noted for SJ, MJ + SJ, and SJ + MJ but not for MJ. Significantly greater increases in PM CSA were observed for MJ, MJ + SJ, and SJ + MJ compared with SJ. Significant increases in TB CSA were noted for SJ, MJ + SJ, and SJ + MJ, but not for MJ, without observed between-group differences. Individual analysis of TB heads showed significantly greater CSA increases in the lateral head for MJ, MJ + SJ, and SJ + MJ compared with SJ. Alternatively, significantly greater increases in the long head were observed for SJ, MJ + SJ, and SJ + MJ compared with MJ. CSA increases for the medial head were statistically similar between conditions. Our findings indicate that muscular adaptations are differentially affected by performance of MJ and SJ exercises.
Jesualdo Cuevas-Aburto, Ivan Jukic, L. Chirosa-Ríos
et al.
Abstract Cuevas-Aburto, J, Jukic, I, Chirosa-Ríos, LJ, González-Hernández, JM, Janicijevic, D, Barboza-González, P, Guede-Rojas, F, and García-Ramos, A. Effect of traditional, cluster, and rest redistribution set configurations on neuromuscular and perceptual responses during strength-oriented resistance training. J Strength Cond Res 36(6): 1490–1497, 2022—This study aimed to compare the acute effect of traditional (TR), cluster (CL), and rest redistribution (RR) set configurations on neuromuscular and perceptual measures of fatigue. Thirty-one resistance-trained men randomly performed a Control session and 3 experimental sessions consisting of the squat (SQ) and bench press (BP) exercises performed against the 10 repetition maximum load using TR (3 sets of 6 repetitions; 3 minutes of interset rest), CL (3 sets of 6 repetitions; 30 seconds of intraset rest every 2 repetitions; 3 minutes of interset rest), and RR (9 sets of 2 repetitions; 45 seconds of interset rest) set configurations. A significant effect of “set configuration” (p = 0.002) was observed for barbell velocity. The average velocity of the training session was lower for TR compared with CL (% difference = 5.09% in SQ and 5.68% in BP) and RR (% difference = 5.92% in SQ and 2.71% in BP). The 3 set configurations induced comparable decrements in countermovement jump height (% difference from −6.0% to −8.1%) and throwing velocity (% difference from −0.6% to −1.2%). Ratings of perceived exertion (RPE-10) values collected after the sets were higher for TR (SQ: 6.9 ± 0.7 a.u.; BP: 6.8 ± 0.8 a.u.) compared with CL (SQ: 6.2 ± 0.8 a.u.; BP: 6.4 ± 0.7 a.u.) and RR (SQ: 6.2 ± 0.8 a.u.; BP: 6.6 ± 0.9 a.u.), while the session RPE did not differ between the set configurations (p = 0.595). CL and RR set configurations allow for higher velocities and lower RPE values during resistance training sessions not performed to failure in comparison with a TR set configuration.
Abstract Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the growth of renal cysts that ultimately destroy kidney function. Mutations in the PKD1 and PKD2 genes cause ADPKD. Their protein products, polycystin-1 (PC1) and polycystin-2 (PC2) have been proposed to form a calcium-permeable receptor-channel complex; however the mechanisms by which they function are almost completely unknown. Most mutations in PKD1 are truncating loss-of-function mutations or affect protein biogenesis, trafficking or stability and reveal very little about the intrinsic biochemical properties or cellular functions of PC1. An ADPKD patient mutation (L4132Δ or ΔL), resulting in a single amino acid deletion in a putative G-protein binding region of the PC1 C-terminal cytosolic tail, was found to significantly decrease PC1-stimulated, G-protein-dependent signaling in transient transfection assays. Pkd1ΔL/ΔL mice were embryo-lethal suggesting that ΔL is a functionally null mutation. Kidney-specific Pkd1ΔL/cond mice were born but developed severe, postnatal cystic disease. PC1ΔL protein expression levels and maturation were comparable to those of wild type PC1, and PC1ΔL protein showed cell surface localization. Expression of PC1ΔL and PC2 complexes in transfected CHO cells failed to support PC2 channel activity, suggesting that the role of PC1 is to activate G-protein signaling to regulate the PC1/PC2 calcium channel.