Rapid detection and quantification of ultralow‐concentration nanoparticles based on nanopore array blockage
Rami Yazbeck, Jiayi Xu, Yiding Zhong
et al.
Abstract Rapid and accurate detection of ultralow‐concentration nanoparticles is crucial for applications ranging from medical diagnosis to water quality monitoring, yet remains challenging for current laser‐based and light‐scattering methods. While nanoparticle‐translocation‐based nanopore sensing offers single‐particle resolution, conventional single‐nanopore resistive pulse sensing approaches suffer from low capture frequency, transient signals, and clogging issues, limiting their effectiveness at extremely low concentrations. Here, we present a novel nanopore array blockage‐based sensing strategy for the rapid detection and quantification of ultralow‐concentration nanoparticles. Using hydraulic force, nanoparticles are driven through an array of subnanoparticle‐sized pores, and optical microscopy monitors blockage progression to obtain quantitative concentration data. Our results demonstrate a linear correlation between the initial blockage rate and nanoparticle concentration, enabling the detection of fluorescent nanoparticles down to 0.5 aM (300 particles/mL) within 5 min—a three‐order‐of‐magnitude improvement in sensitivity over previous nanopore‐based methods. Additionally, our approach can leverage fluorescent nanoparticles as probes to detect unlabeled nanoparticles and contaminants at similarly low concentrations. This strategy provides a robust, efficient, and rapid platform for ultrasensitive nanoparticle detection, with promising applications in biomedical research, environmental monitoring, and industrial quality control.
Descriptive and experimental mechanics
Enhancement of Aerodynamic Performance of Two Adjacent H-Darrieus Turbines Using a Dual-Rotor Configuration
Douha Boulla, Saïf ed-Dîn Fertahi, Maryam Bernatchou
et al.
Improvements in the aerodynamic performance of the H-Darrieus turbine are crucial to address future energy requirements. This work aims to optimize the behavior of two adjacent turbines through the addition of a dual H-Darrieus rotor. The first rotor is composed of three NACA 0021 blades, while the second comprises a single Eppler 420 blade. This study focuses on 2D CFD simulation based on the solution of the unsteady Reynolds-averaged Navier–Stokes (URANS) equations, using the sliding mesh method and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>k</mi><mo>−</mo><mi>ω</mi></mrow></semantics></math></inline-formula> SST turbulence model. The simulation results indicate a 17% improvement in the efficiency of the two turbines integrating dual rotors, compared to the two isolated turbines, for <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>α</mi></mrow></semantics></math></inline-formula> = 0°. Moreover, the power coefficient <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mrow><mo> </mo><mo>(</mo><mi>C</mi></mrow><mrow><mi>P</mi></mrow></msub><mo>)</mo></mrow></semantics></math></inline-formula> reaches maximum values of 0.49, 0.42, and 0.40 for angles of attack of 30°, 25°, and 20°, respectively, at TSR = 2.51. Conversely, the selection of an optimal angle of attack allows the efficiency of the two H-Darrieus turbines to be increased. It is also shown by the results that the effect of stagnation is reduced and lift is maximized when the optimum distance between two adjacent turbines is chosen. Moreover, the overall aerodynamic performance of the system is enhanced by the potential of a dual-rotor configuration, and the wake between the two turbines is disrupted, which can result in a decrease in energy production within wind farms.
Thermodynamics, Descriptive and experimental mechanics
Assessing Pedestrian Comfort in Dense Urban Areas Using CFD Simulations: A Study on Wind Angle and Building Height Variations
Paulo Ulisses da Silva, Gustavo Bono, Marcelo Greco
Pedestrian wind comfort is a critical factor in the design of sustainable and livable dense urban areas. This study systematically investigates the effects of surrounding building height and wind incidence angle on pedestrian-level wind conditions, analyzing a nine-building arrangement through validated Computational Fluid Dynamics (CFD) simulations. Scenarios included neighborhood heights varying from 0L to 6L and wind angles from 0° to 45°. The results reveal that wind angles aligned with urban canyons (0° case) induce a strong Venturi effect, creating hazardous conditions with Mean Velocity Ratio (MVR) peaks reaching 3.42. Conversely, an oblique 45° angle mitigates high speeds by promoting flow recirculation. While increasing neighborhood height generally intensifies channeling, the study also highlights that even an isolated building (0L case) can generate hazardous localized velocities due to flow separation around its corners. The Overall Mean Velocity Ratio (OMVR) analysis identifies that, among the studied cases, a 2L neighborhood height is the most tolerable configuration, striking a balance between sheltering and channeling effects. Ultimately, these findings highlight for urban planners the importance of analyzing diverse geometric configurations and wind scenarios, reinforcing the value of CFD as an essential tool for designing safer and more comfortable public spaces.
Thermodynamics, Descriptive and experimental mechanics
Analytical model and experimental validation for nonlinear mechanical response of aspirated elastic shells
Kazutoshi Masuda, Miho Yanagisawa
We developed a physics-based analytical model to describe the nonlinear mechanical response of aspirated elastic shells. By representing the elastic energy through a stretching modulus, $K$, and a dimensionless ratio, $δ$, capturing the balance between stretching and bending energies, the model reveals mechanical behaviors extending beyond conventional approaches. Validated across microscale droplets and macroscale silicone sheets by fitting experimental force-displacement curves, this approach provides accurate, scalable characterization of deformed elastic shells. This framework advances our understanding of soft thin-shell mechanics, with broad applications in probing living cells and designing soft materials.
en
cond-mat.soft, physics.bio-ph
An analytical nonlinear displacement model of electrothermal V-shaped actuator
Kien Trung Hoang, Vu Cong Ham, Phuc Hong Pham
et al.
This work presents an analytical model to determine nonlinear displacements of electrothermal V-shaped actuators. The nonlinear displacement model of V-shaped beams fixed at both ends is established based on considering the axial deformation of the beam. The 3D model of the V-shaped microactuator was established to verify the theoretical nonlinear model. The evaluation shows that the displacement deviation between the analytical nonlinear model and simulation is approximately 7.7% at the driving voltage of 16 V. This confirms the advantages of the proposed model to predict more precisely the displacement of the electrothermal V-shaped actuator.
Mechanical engineering and machinery, Descriptive and experimental mechanics
Pressure Drop Estimation of Two-Phase Adiabatic Flows in Smooth Tubes: Development of Machine Learning-Based Pipelines
Farshad Bolourchifard, Keivan Ardam, Farzad Dadras Javan
et al.
The current study begins with an experimental investigation focused on measuring the pressure drop of a water–air mixture under different flow conditions in a setup consisting of horizontal smooth tubes. Machine learning (ML)-based pipelines are then implemented to provide estimations of the pressure drop values employing obtained dimensionless features. Subsequently, a feature selection methodology is employed to identify the key features, facilitating the interpretation of the underlying physical phenomena and enhancing model accuracy. In the next step, utilizing a genetic algorithm-based optimization approach, the preeminent machine learning algorithm, along with its associated optimal tuning parameters, is determined. Ultimately, the results of the optimal pipeline provide a Mean Absolute Percentage Error (MAPE) of 5.99% on the validation set and 7.03% on the test. As the employed dataset and the obtained optimal models will be opened to public access, the present approach provides superior reproducibility and user-friendliness in contrast to existing physical models reported in the literature, while achieving significantly higher accuracy.
Thermodynamics, Descriptive and experimental mechanics
Tripartite entanglement from experimental data: $B^0\to K^{*0}μ^+μ^-$ as a case study
Roberto A. Morales, Alejandro Szynkman
We develop an angular analysis based on the reconstruction of the helicity amplitudes from dedicated experimental data corresponding to the tripartite state composed by one qutrit and two qubits, which arises in the three-body decays of a spin zero particle into one vector and a fermion pair. Starting from the associated spin density matrix of the final state, entanglement quantifiers were investigated and the corresponding significances were determined up to second order in the error propagation of the uncertainties of the angular measurements. As an application of our analysis, we performed a full quantum tomography of the final state in the $B^0\to K^{*0}μ^+μ^-$ decays using data recorded by LHCb collaboration. We found the presence of genuine quantum entanglement of the final state and also in both kaon-muon and di-muon subsystems. In recent years, $B$ meson decays received significant attention from both experimental and theoretical sides, and the proposed observables provide novel perspectives for studying them. Furthermore, this analysis could be also applied to other several processes if the complete experimental data were available for the helicity amplitudes reconstruction.
Domain-Independent Automatic Generation of Descriptive Texts for Time-Series Data
Kota Dohi, Aoi Ito, Harsh Purohit
et al.
Due to scarcity of time-series data annotated with descriptive texts, training a model to generate descriptive texts for time-series data is challenging. In this study, we propose a method to systematically generate domain-independent descriptive texts from time-series data. We identify two distinct approaches for creating pairs of time-series data and descriptive texts: the forward approach and the backward approach. By implementing the novel backward approach, we create the Temporal Automated Captions for Observations (TACO) dataset. Experimental results demonstrate that a contrastive learning based model trained using the TACO dataset is capable of generating descriptive texts for time-series data in novel domains.
A Millimeter-Wave Software-Defined Radio for Wireless Experimentation
Alphan Şahin, Mihail L. Sichitiu, İsmail Guvenç
In this study, we propose a low-cost and portable millimeter-wave software-defined radio (SDR) for wireless experimentation in the 60 GHz band. The proposed SDR uses Xilinx RFSoC2x2 and Sivers EVK06002 homodyne transceiver and provides a TCP/IP-based interface for companion computer (CC)-based baseband signal processing. To address the large difference between the processing speed of the CC and the sample rate of analog-to-digital converters, we propose a method, called waveform-triggered reception (WTR), where a hard-coded block detects a special trigger waveform to acquire a pre-determined number of IQ samples upon the detection. We also introduce a buffer mechanism to support discontinuous transmissions. By utilizing the WTR along with discontinuous transmissions, we conduct a beam sweeping experiment, where we evaluate 4096 beam pairs rapidly without compromising the flexibility of the CC-based processing. We also generate a dataset that allows one to calculate physical layer parameters such as signal-to-noise ratio and channel frequency response for a given pair of transmit and receive beam indices.
Two Methods to Improve the Efficiency of Supersonic Flow Simulation on Unstructured Grids
Andrei S. Kozelkov, Andrei V. Struchkov, Dmitry Y. Strelets
The paper presents two methods to improve the efficiency of supersonic flow simulation using arbitrarily shaped unstructured grids. The first method promotes increasing the numerical solution convergence rate and is based on the geometric multigrid method for initialization of the flow field. The method is used to obtain the initial field of distributed physical quantity values, which maximally corresponds to the converged solution. For this purpose, the problem simulation is performed on a series of coarse grids beginning from the coarsest one in this series. Upon completion of simulations, the solution obtained is interpolated to a finer grid and used for initialization of simulations on this grid. The second method allows increasing the numerical solution accuracy and is based on statically adapting the computational grid to the flow specifics. The static adaptation algorithm provides automatic refinement of the computational grid in the region of specific features of flow, such as shock waves typical for supersonic flows. This algorithm provides a better description of the shock-wave front owing to the local grid refinement, with the local refinement region being automatically selected. Results of using these methods are demonstrated for the two supersonic aerodynamics problems: the simulation of the bow shock strength at a given distance under axially symmetric body Seeb-ALR and a mock-up aircraft Lockheed Martin 1021. It is shown that in both cases, the numerical solution convergence rate is increased owing to the use of the geometric multigrid method for initialization and a higher quality and a higher accuracy of solution is gained owing to the local grid refinement (using static adaptation means) near the shock-wave front.
Thermodynamics, Descriptive and experimental mechanics
Viscoelastic Representation of the Operation of Sucker Rod Pumps
Sheldon Wang, Lynn Rowlan, Abbey Henderson
et al.
The issues of leakage with respect to the clearance between the pump plunger outer surface and the pump barrel inner surface and other operational conditions have been revisited in this paper. Both Poiseuille flow rate due to the pressure difference and Couette flow rate due to the plunger motion have been considered. The purpose of this study is to explore the possibility of representing the entire downhole pump system with a simple viscoelastic model. We have explored both Kelvin and Maxwell viscoelastic models along with the dynamic behaviors of a mass point attached to the viscoelastic model. By using the time-dependent polished rod force measured with a dynamometer as the input to the viscoelastic models, we have obtained the displacement responses, which match closely with the actual measurements in experiments and operations. Further study and experiments have been planned and partially implemented in the McCoy School of Engineering at Midwestern State University, a member of the Texas Tech University System.
Thermodynamics, Descriptive and experimental mechanics
Application of Direct Numerical Simulation to Determine the Correlation Describing Friction Losses during the Transverse Flow of Fluid in Hexagonal Array Pin Bundles
Yury E. Shvetsov, Yury S. Khomyakov, Mikhail V. Bayaskhalanov
et al.
This paper presents the results of a numerical simulation to determine the hydraulic resistance for a transverse flow through the bundle of hexagonal rods. The calculations were carried out using the precision CFD code CONV-3D, intended for direct numerical simulation of the flow of an incompressible fluid (DNS-approximation) in the parts of fast reactors cooled by liquid metal. The obtained dependencies of the pressure drop and the coefficient of anisotropy of friction on the Reynolds number can be used in the thermal-hydraulic codes that require modeling of the flow in similar structures and, in particular, in the inter-wrapper space of the reactor core.
Thermodynamics, Descriptive and experimental mechanics
Homogenization of discrete mesoscale model of concrete for coupled mass transport and mechanics by asymptotic expansion
Jan Eliáš, Gianluca Cusatis
Mass transport phenomenon in concrete structures is strongly coupled with their mechanical behavior. The first coupling fabric is the Biot's theory according to which fluid pressure interacts with solid stress state and volumetric deformation rate of the solid induces changes in fluid pressure. Another coupling mechanism emerges with cracks which serve as channels for the fluid to flow through them and provide volume for fluid storage. Especially the second coupling mechanism presents a challenge for numerical modeling as it requires detailed knowledge about cracking process. Discrete mesoscale mechanical models coupled with mass transport offer simple and robust way to solve the problem. On the other hand, however, they are computationally demanding. In order to reduce this computational burden, the present paper applies the asymptotic expansion homogenization technique to the coupled problem to deliver (i) continuous and homogeneous description of the macroscopic problem which can be easily solved by the finite element method, (ii) discrete and heterogeneous mesoscale problem in the periodic setup attached to each integration point of the macroscale along with (iii) equations providing communication between these two scales. The transient terms appear at the macroscale only, as well as the Biot's coupling terms. The coupling through cracking is treated at the mesoscale by changing conductivity of the conduit elements according to the mechanical solution, otherwise the two mesoscale steady state problems are decoupled and can be therefore solved in a sequence. This paper presents verification studies showing performance of the homogenized solution.
Stability and Consolidation of Sediment Tailings Incorporating Unsaturated Soil Mechanics
Alfrendo Satyanaga, Martin Wijaya, Qian Zhai
et al.
Tailing dams are commonly used to safely store tailings without damaging the environment. Sand tailings (also called Sediment tailings) usually have a high water content and hence undergo consolidation during their placement. As the sediment tailings are usually placed above the ground water level, the degree of saturation and permeability of the sediment tailing is associated with the unsaturated condition due to the presence of negative pore-water pressure or suction. Current practices normally focus on the analyses saturated conditions. However, this consolidation process requires the flow of water between saturated and unsaturated zones to be considered. The objective of this study is to investigate the stability and consolidation of sediment tailings for the construction of road pillars considering the water flow between saturated and unsaturated zones. The scope of this study includes the unsaturated laboratory testing of sediments and numerical analyses of the road pillar. The results show that the analyses based on saturated conditions overestimate the time required to achieve a 90% degree of consolidation. The incorporation of the unsaturated soil properties is able to optimize the design of slopes for road pillars into steeper slope angles.
Thermodynamics, Descriptive and experimental mechanics
Open Water Flume for Fluid Mechanics Lab
Rachmadian Wulandana
Open water flume tanks with closed-loop circulation driven by centrifugal pumps are essential for hydro experimentation in academic settings as well as research centers. The device is also attractive due to its versatility and easy-to-maintain characteristics. Nevertheless, commercial open flume systems can be expensive and become less prioritized in engineering schools. This paper describes the design and fabrication of an affordable, medium-size water flume tank, suitable for education purposes. The central piece of the system is a transparent observation chamber where fluid experiments are typically conducted and observed. The expected maximum average water speed in the observation chamber of about 60 cm per second was achieved by the inclusion of a 3 hp centrifugal pump. The size and capacity of the current design were constrained by space limitation and available funds. The educational facility was assigned as a two-semester multi-disciplinary capstone senior design project incorporating students and faculty of mechanical, electrical, and computer engineering programs in our campus. The design process provides a training platform for skills in the area of Computer Aided Designs (CAD), Finite Element Analysis (FEA), Computational Fluid Dynamics (CFD), manufacturing, and experimentation. The multi-disciplinary project has contributed to the improvement of soft skills, such as time management, team working, and professional presentation, of the team members. The total material cost of the facility was less than USD 6000, which includes the pump and its variable frequency driver. The project was made possible due to the generous sponsor of the Vibration Institute.
Thermodynamics, Descriptive and experimental mechanics
Magneto-Bioconvection Flow of Williamson Nanofluid over an Inclined Plate with Gyrotactic Microorganisms and Entropy Generation
Tunde A. Yusuf, Fazle Mabood, B. C. Prasannakumara
et al.
The fluid flow through inclined plates has several applications in magneto-aerodynamics, materials processing and magnetohydrodynamic propulsion thermo-fluid dynamics. Inspired by these applications, the rate of entropy production in a bio-convective flow of a magnetohydrodynamic Williamson nanoliquid over an inclined convectively heated stretchy plate with the influence of thermal radiation, porous materials and chemical reaction has been deliberated in this paper. The presence of microorganisms aids in stabilizing the suspended nanoparticles through a bioconvection process. Also, the thermal radiation assumed an optically thick limit approximation. With the help of similarity transformations, the coupled partial differential equations are converted to nonlinear ordinary differential equations and the resulting model is numerically tackled using the shooting method. The influences of the determining thermo-physical parameters on the flow field are incorporated and extensively discussed. The major relevant outcomes of the present analysis are that the upsurge in values of Schmidt number decays the mass transfer characteristics, but the converse trend is depicted for boost up values of the thermophoresis parameter. Enhancement in bioconvection Peclet and Schmidt numbers deteriorates the microorganism density characteristics. Further, the upsurge in the Williamson parameter declines the Bejan number and irreversibility ratio.
Thermodynamics, Descriptive and experimental mechanics
Influence of a Standing Wave Flow-Field on the Dynamics of a Spray Diffusion Flame
J. Barry Greenberg, David Katoshevski
A theoretical investigation of the influence of a standing wave flow-field on the dynamics of a laminar two-dimensional spray diffusion flame is presented for the first time. The mathematical analysis permits mild slip between the droplets and their host surroundings. For the liquid phase, the use of a small Stokes number as the perturbation parameater enables a solution of the governing equations to be developed. Influence of the standing wave flow-field on droplet grouping is described by a specially constructed modification of the vaporization Damkohler number. Instantaneous flame front shapes are found via a solution for the usual Schwab–Zeldovitch parameter. Numerical results obtained from the analytical solution uncover the strong bearing that droplet grouping, induced by the standing wave flow-field, can have on flame height, shape, and type (over- or under-ventilated) and on the existence of multiple flame fronts.
Thermodynamics, Descriptive and experimental mechanics
Canonical Nambu mechanics: relevance to string/M-theory and approaches to quantization
Tamiaki Yoneya
We review some aspects of Nambu mechanics on the basis of the works previously published separately by the present author. Main focuses are on three themes, its various symmetry structures, their possible relevance to string/M theory, and a Hamilton-Jacobi like reformulation. We try to elucidate the basic ideas, most of which were rooted in more or less the same ground, and to explain motivations behind these works from a unified and vantage viewpoint. Various unsolved questions are mentioned. We also include some historical account on the genesis of the Nambu mechanics, and discuss (in the Appendix) some parallelism of various ideas behind the Nambu's paper with Dirac's old works which are related to the description of vortical flows in terms of gauge potentials.
Experimental Demonstration of Broadband Reconfigurable Mechanical Nonreciprocity
Amin Mehrvarz, Mohammad Javad Khodaei, Amir Darabi
et al.
Breaking reciprocity has recently gained significant attention due to its broad range of applications in engineering systems. Here, we introduce the first experimental demonstration of a broadband mechanical beam waveguide, which can be reconfigured to represent wave nonreciprocity. This is achieved by using spatiotemporal stiffness modulation with piezoelectric patches in a closed-loop controller. Using a combination of analytical methods, numerical simulations, and experimental measurements, we show that contrary to the conventional shunted piezoelectrics or nonlinearity based methods, our setup is stable, less complicated, reconfigurable, and precise over a broad range of frequencies. Our reconfigurable nonreciprocal system has potential applications in phononic logic, wave diodes, energy trapping, and localization.
Dolores National High School
Manuel O. Tegerero