Hasil untuk "Architecture"

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S2 Open Access 2010
Oral Biofilm Architecture on Natural Teeth

V. Zijnge, M. B. M. V. Leeuwen, J. Degener et al.

Periodontitis and caries are infectious diseases of the oral cavity in which oral biofilms play a causative role. Moreover, oral biofilms are widely studied as model systems for bacterial adhesion, biofilm development, and biofilm resistance to antibiotics, due to their widespread presence and accessibility. Despite descriptions of initial plaque formation on the tooth surface, studies on mature plaque and plaque structure below the gum are limited to landmark studies from the 1970s, without appreciating the breadth of microbial diversity in the plaque. We used fluorescent in situ hybridization to localize in vivo the most abundant species from different phyla and species associated with periodontitis on seven embedded teeth obtained from four different subjects. The data showed convincingly the dominance of Actinomyces sp., Tannerella forsythia, Fusobacterium nucleatum, Spirochaetes, and Synergistetes in subgingival plaque. The latter proved to be new with a possibly important role in host-pathogen interaction due to its localization in close proximity to immune cells. The present study identified for the first time in vivo that Lactobacillus sp. are the central cells of bacterial aggregates in subgingival plaque, and that Streptococcus sp. and the yeast Candida albicans form corncob structures in supragingival plaque. Finally, periodontal pathogens colonize already formed biofilms and form microcolonies therein. These in vivo observations on oral biofilms provide a clear vision on biofilm architecture and the spatial distribution of predominant species.

668 sitasi en Biology, Medicine
S2 Open Access 2009
OPC Unified Architecture

U. Enste, W. Mahnke

Zusammenfassung OPC Unified Architecture bietet erweiterte Möglichkeiten der Interoperabilität. Auf Basis eines objekt-orientierten Konzeptes stehen moderne Mittel zur Informationsmodellierung zur Verfügung, um den über Schnittstellen zur Verfügung zu stellenden Datenhaushalt eines Systems repräsentieren zu können. Mit Hilfe einer Kommunikationsinfrastruktur werden darüber hinaus eine Systemarchitektur und generische Dienstevorgaben gemacht. Abstract OPC Unified Architecture offers extended functionalities to realize interoperability between different systems. Based on object-oriented concepts, modern means for information modelling are available to represent the data base of a system, which should be shareable via an OPC UA interface. In addition to the information modelling aspects, OPC UA specifies a communication infrastructure by defining generic services and a system architecture.

657 sitasi en Computer Science, Engineering

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