Hasil untuk "physics.geo-ph"

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S2 Open Access 1973
Determination of intracellular pH by 31P magnetic resonance.

R. B. Moon, J. Richards

Observation of the ^(31)P signal from various intracellular phosphates can provide a convenient, nondestructive technique for determining intracellular conditions such as pH. This procedure has been explored with particular reference to the erythrocyte. Both the chemical shift of intracellular inorganic phosphate relative to that of serum phosphate and the positions of, and more especially the difference between, the chemical shifts of 2,3-diphosphoglycerate have been used to monitor intracellular pH of erythrocytes whose hemoglobin has been liganded with carbon monoxide.

1100 sitasi en Chemistry, Medicine
S2 Open Access 1982
Cytoplasmic pH and free Mg2+ in lymphocytes

T. Rink, R. Tsien, T. Pozzan

Measurements have been made of cytoplasmic pH, (pHi) and free Mg2+ concentration, ( [Mg2+]i), in pig and mouse lymphocytes. pHi was measured in four ways: by a digitonin null-point technique; by direct measurement of the pH of freeze-thawed cell pellets; from the 31P nuclear magnetic resonance (NMR) spectrum of intracellular inorganic phosphate; and by the use of a newly synthesized, intracellularly- trappable fluorescent pH indicator. In HEPES buffered physiological saline with pH 7.4 at 37 degrees C, pHi was close to 7.0. Addition of physiological levels of HCO3- and CO2 transiently acidified the cells by approximately 0.1 U. Mitogenic concentrations of concanavalin A (Con A) had no measurable effect on pH in the first hour. [Mg2+]i was assessed in three ways: (a) from the external Mg2+ null-point at which the ionophore A23187 produced no net movement of Mg2+ or H+; (b) by Mg- sensitive electrode measurements in freeze-thawed pellets; and (c) from the 31P nuclear magnetic resonance spectrum of the gamma-phosphate of intracellular ATP. Total cell Mg2+ was approximately 12 mmol per liter cell water. The NMR data indicated [Mg2+]i greater than 0.5 mM. The null-point method gave [Mg2+]i approximately 0.9 nM. The electrode measurements gave 1.35 mM, which was thought to be an overestimate. Exposure to mitogenic doses of Con A for 1 h gave no detectable change in total or free Mg2+.

992 sitasi en Medicine, Biology
S2 Open Access 1976
Intracellular pH transients in squid giant axons caused by CO2, NH3, and metabolic inhibitors

W. Boron, P. De Weer

The intracellular pH (pHi) of squid giant axons has been measured using glass pH microelectrodes. Resting pHi in artificial seawater (ASW) (pH 7.6-7.8) at 23 degrees C was 7.32 +/- 0.02 (7.28 if corrected for liquid junction potential). Exposure of the axon to 5% CO2 at constant external pH caused a sharp decrease in pHi, while the subsequent removal of the gas caused pHi to overshoot its initial value. If the exposure to CO2 was prolonged, two additional effects were noted: (a) during the exposure, the rapid initial fall in pHi was followed by a slow rise, and (b) after the exposure, the overshoot was greatly exaggerated. Application of external NH4Cl caused pHi to rise sharply; return to normal ASW caused pHi to return to a value below its initial one. If the exposure to NH4Cl was prolonged, two additional effects were noted: (a) during the exposure, the rapid initial rise in pHi was followed by a slow fall, and (b) after the exposure, the undershoot was greatly exaggerated. Exposure to several weak acid metabolic inhibitors caused a fall in pHi whose reversibility depended upon length of exposure. Inverting the electrochemical gradient for H+ with 100 mM K- ASW had no effect on pHi changes resulting from short-term exposure to azide. A mathematical model explains the pHi changes caused by NH4Cl on the basis of passive movements of both NH3 and NH4+. The simultaneous passive movements of CO2 and HCO3-cannot explain the results of the CO2 experiments; these data require the postulation of an active proton extrusion and/or sequestration mechanism.

947 sitasi en Chemistry, Medicine
arXiv Open Access 2026
Optimization of Cost Functions in Absolute Plate Motion Modeling

James Unwin, Steve Zhang

We consider the implementation of optimization techniques within the study of tectonic plate motion. Specifically, we examine the optimization underlying optAPM, a leading code for modeling absolute plate motion. We highlight that modifications in the construction of the objective function, composed of individual cost functions, can improve modelling performance. In particular, we propose a simpler and more intuitive formulation of the hotspot cost function. A key part of the new hotspot analysis is the pre-interpolation of hotspot trail data, crucial geological markers for validating absolute plate motion over O(100) Myr timescales. By reducing the propagation of modeling errors, our refined model provides more precise reconstructions of historical plate movements. Our modified hotspot modelling improves the accuracy and reliability of the optAPM outputs.

en physics.geo-ph, cs.CE
arXiv Open Access 2025
Winter Noctilucent Clouds Following Sudden Stratospheric Warming: First Observations

Oleg S. Ugolnikov

Mesospheric structures identical to summer noctilucent clouds were observed during the nights of December 17-19, 2024 in Siberian Russia. Basing on the available photo data, the mean altitude of the clouds 70.1+-1.5 km was measured by umbral colorimetric method. This coincided spatially and temporary with deep temperature minimum below 160K in mesosphere, followed the polar vortex displacement and warming of stratosphere below the clouds. The satellite data on temperature and water vapor is used to study the nature of this unexpected event.

en physics.ao-ph, physics.geo-ph
S2 Open Access 2010
Denitrification gene pools, transcription and kinetics of NO, N2O and N2 production as affected by soil pH.

Binbin Liu, P. Mørkved, Å. Frostegård et al.

The N(2)O : N(2) product ratio of denitrification is negatively correlated with soil pH, but the mechanisms involved are not clear. We compared soils from field experiments where the pH had been maintained at different levels (pH 4.0-8.0) by liming (> or = 20 years), and quantified functional gene pools (nirS, nirK and nosZ), their transcription and gas kinetics (NO, N(2)O and N(2)) of denitrification as induced by anoxic incubation with and without a carbon substrate (glutamate). Denitrification in unamended soil appeared to be based largely on the activation of a pre-existing denitrification proteome, because constant rates of N(2) and N(2)O production were observed, and the transcription of functional genes was below the detection level. In contrast, glutamate-amended soils showed sharp peaks in the transcripts of nirS and nosZ, increasing the rates of denitrification and pH-dependent transient accumulation of N(2)O. The results indicate that the high N(2)O : N(2) product ratio at low pH is a post-transcriptional phenomenon, because the transcription rate of nosZ relative to that of nirS was higher at pH 6.1 than at pH 8.0. The most plausible explanation is that the translation/assembly of N(2)O reductase is more sensitive to low pH than that of the other reductases involved in denitrification.

494 sitasi en Biology, Medicine
S2 Open Access 2014
Measurement of Higgs boson production in the diphoton decay channel in pp collisions at center-of-mass energies of 7 and 8 TeV with the ATLAS detector

G. Aad, B. Abbott, J. Abdallah et al.

A measurement of the production processes of the recently discovered Higgs boson is performed in the two-photon final state using 5.4 fb$^{-1}$ of proton-proton collisions data at $\sqrt{s}=7$ TeV and 20.3 fb$^{-1}$ at $\sqrt{s}=8$ TeV collected by the ATLAS detector at the Large Hadron Collider. The number of observed Higgs boson decays to diphotons divided by the corresponding Standard Model prediction, called the signal strength, is found to be $\mu = 1.17 \pm 0.27$ at the value of the Higgs boson mass measured by ATLAS, $m_{H}$ = 125.4 GeV. The analysis is optimized to measure the signal strengths for individual Higgs boson production processes at this value of $m_{H}$. They are found to be $\mu_{\mathrm{ggF}} = 1.32 \pm 0.38$, $\mu_{\mathrm{VBF}} = 0.8 \pm 0.7$, $\mu_{{WH}} = 1.0 \pm 1.6 $, $\mu_{{ZH}} = 0.1 ^{+3.7}_{-0.1} $, $\mu_{{t\bar{t}H}} = 1.6 ^{+2.7}_{-1.8} $, for Higgs boson production through gluon fusion, vector-boson fusion, and in association with a $W$ or $Z$ boson or a top-quark pair, respectively. Compared with the previously published ATLAS analysis, the results reported here also benefit from a new energy calibration procedure for photons and the subsequent reduction of the systematic uncertainty on the diphoton mass resolution. No significant deviations from the predictions of the Standard Model are found.

339 sitasi en Physics
arXiv Open Access 2024
Information theory, Signal Analysis and Inverse Problem

Dominique Gibert, Fernando Lopes, Vincent Courtillot et al.

This book is intended for teaching Signal Analysis methods and Inverse Problems theory. It is completely open access and will remain free. It is currently illustrated with examples that we have actually encountered in geophysics, but will eventually evolve to address problems in biology. The main idea is to develop this material over time (probably every six months) and throughout our careers. Therefore, it is not yet complete and some minor points need to be corrected in this English version. It is also available in French ( https://www.dropbox.com/scl/fi/yx9le4tbwjg0ur7llp0fj/TheorieInfoTTS_vf.pdf?rlkey=uvc1ku8v4ihhogkcy0w2iixdf&st=gcddwegm&dl=0 ) and Portuguese ( https://www.dropbox.com/scl/fi/mx46mgn66ob3r1z9r0igq/TheorieInfoTTS_vp.pdf?rlkey=c8m9e8dmbwf1npu4bwfqkhblr&st=xveovcvs&dl=0 ). The MATLAB codes we used can be found at the following address: https://www.dropbox.com/scl/fi/6tedk1xyquswmh0vcekfi/matlab_book.zip?rlkey=cbj5ura63qy6u57ij2yzgggkw&st=8gp4gddd&dl=0

en physics.geo-ph, physics.bio-ph
arXiv Open Access 2024
Could Ball Lightning Be Magnetic Monopoles?

Karl D. Stephan

While magnetic monopoles have extensive theoretical justification for their existence, but have proved elusive to observe, ball lightning is both relatively frequently observed and largely unexplained theoretically. It was first proposed in 1990 that ball lightning might result from the catalysis of nuclear fission by a magnetic monopole. The observed frequency of ball lightning does not conflict with current upper theoretical or observational bounds for magnetic monopole flux. Some possible mechanisms to account for the association of magnetic-monopole-caused ball lightning with thunderstorms are described, and proposals for further observational and theoretical research are made.

en hep-ph, physics.geo-ph
S2 Open Access 2015
Evidence for the Higgs-boson Yukawa coupling to tau leptons with the ATLAS detector

G. Aad, B. Abbott, J. Abdallah et al.

Results of a search for H → ττ decays are presented, based on the full set of proton-proton collision data recorded by the ATLAS experiment at the LHC during 2011 and 2012. The data correspond to integrated luminosities of 4.5 fb−1 and 20.3 fb−1 at centre-of-mass energies of s=7\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ \sqrt{s}=7 $$\end{document} TeV and s=8\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ \sqrt{s}=8 $$\end{document} TeV respectively. All combinations of leptonic (τ→ℓνν¯\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ \tau \to \ell \nu \overline{\nu} $$\end{document} with ℓ = e, μ) and hadronic (τ → hadrons ν) tau decays are considered. An excess of events over the expected background from other Standard Model processes is found with an observed (expected) significance of 4.5 (3.4) standard deviations. This excess provides evidence for the direct coupling of the recently discovered Higgs boson to fermions. The measured signal strength, normalised to the Standard Model expectation, of μ = 1. 43− 0.37+ 0.43 is consistent with the predicted Yukawa coupling strength in the Standard Model.

295 sitasi en Physics
arXiv Open Access 2022
Accelerated 3D Electrical Resistivity Tomography with a Scalable Jacobian-free Approach

Jonghyun Lee

A Jacobian-free inversion method is presented to accelerate Electrical Resistivity Tomography (ERT) for shallow aquifer characterization. The ERT problem typically implements the adjoint state method to efficiently compute Jacobian during the inversion. However, the adjoint state method needs intrusive forward model code changes and may not be computationally scalable with many observations especially when one performs 3D ERT surveys with dense multi-electrode arrays. Here the Principal Component Geostatistical Approach (PCGA), a fast and scalable Jacobian-free inverse modeling method, is applied to solve a high dimensional data-intensive ERT problem. The PNNL's ERT simulation software E4D was linked to the python interface pyPCGA without intrusive code change and the example code is upload in a public repository. The result in this study shows that high-resolution 3D subsurface characterization is computationally feasible, which would have a great potential for implementations in practice.

en physics.geo-ph, physics.comp-ph

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