Hasil untuk "Consciousness. Cognition"

R. McCrae, P. Costa

C. Izard

S. Cartwright-Hatton, A. Wells

David Whitney, A. Leib

N. Ellis

Itay Shani

C. Hughes, C. Boncyk, D. Culley et al.

Postoperative delirium is a geriatric syndrome that manifests as changes in cognition, attention, and levels of consciousness after surgery. It occurs in up to 50% of patients after major surgery and is associated with adverse outcomes, including increased hospital length of stay, higher cost of care, higher rates of institutionalization after discharge, and higher rates of readmission. Furthermore, it is associated with functional decline and cognitive impairments after surgery. As the age and medical complexity of our surgical population increases, practitioners need the skills to identify and prevent delirium in this high-risk population. Because delirium is a common and consequential postoperative complication, there has been an abundance of recent research focused on delirium, conducted by clinicians from a variety of specialties. There have also been several reviews and recommendation statements; however, these have not been based on robust evidence. The Sixth Perioperative Quality Initiative (POQI-6) consensus conference brought together a team of multidisciplinary experts to formally survey and evaluate the literature on postoperative delirium prevention and provide evidence-based recommendations using an iterative Delphi process and Grading of Recommendations Assessment, Development and Evaluation (GRADE) Criteria for evaluating biomedical literature.

Lucie Bréchet, D. Brunet, G. Birot et al.

The temporal structure of self-generated cognition is a key attribute to the formation of a meaningful stream of consciousness. When at rest, our mind wanders from thought to thought in distinct mental states. Despite the marked importance of ongoing mental processes, it is challenging to capture and relate these states to specific cognitive contents. In this work, we employed ultra-high field functional magnetic resonance imaging (fMRI) and high-density electroencephalography (EEG) to study the ongoing thoughts of participants instructed to retrieve self-relevant past episodes for periods of 22sec. These task-initiated, participant-driven activity patterns were compared to a distinct condition where participants performed serial mental arithmetic operations, thereby shifting from self-related to self-unrelated thoughts. BOLD activity mapping revealed selective enhanced activity in temporal, parietal and occipital areas during the memory compared to the mental arithmetic condition, evincing their role in integrating the re-experienced past events into conscious representations during memory retrieval. Functional connectivity analysis showed that these regions were organized in two major subparts, previously associated to "scene-reconstruction" and "self-experience" subsystems. EEG microstate analysis allowed studying these participant-driven thoughts in the millisecond range by determining the temporal dynamics of brief periods of stable scalp potential fields. This analysis revealed selective modulation of occurrence and duration of specific microstates in the memory and in the mental arithmetic condition, respectively. EEG source analysis revealed similar spatial distributions of the sources of these microstates and the regions identified with fMRI. These findings imply a functional link between BOLD activity changes in regions related to a certain mental activity and the temporal dynamics of mentation, and support growing evidence that specific fMRI networks can be captured with EEG as repeatedly occurring brief periods of integrated coherent neuronal activity, lasting only fractions of seconds.

E. Lancaster

Autoimmune encephalitis causes subacute deficits of memory and cognition, often followed by suppressed level of consciousness or coma. A careful history and examination may show early clues to particular autoimmune causes, such as neuromyotonia, hyperekplexia, psychosis, dystonia, or the presence of particular tumors. Ancillary testing with MRI and EEG may be helpful for excluding other causes, managing seizures, and, rarely, for identifying characteristic findings. Appropriate autoantibody testing can confirm specific diagnoses, although this is often done in parallel with exclusion of infectious and other causes. Autoimmune encephalitis may be divided into several groups of diseases: those with pathogenic antibodies to cell surface proteins, those with antibodies to intracellular synaptic proteins, T-cell diseases associated with antibodies to intracellular antigens, and those associated with other autoimmune disorders. Many forms of autoimmune encephalitis are paraneoplastic, and each of these conveys a distinct risk profile for various tumors. Tumor screening and, if necessary, treatment is essential to proper management. Most forms of autoimmune encephalitis respond to immune therapies, although powerful immune suppression for weeks or months may be needed in difficult cases. Autoimmune encephalitis may relapse, so follow-up care is important.

Ronen Hershman, Eldad Keha, Lisa Beckmann et al.

In cognitive control tasks, participants are typically instructed to respond to a task-relevant dimension of a stimulus while ignoring the task-irrelevant one(s). In such experiments, task conflict reflects the additional effort associated with performing two tasks, such as identifying the color while reading the word in the color-word Stroop task. Task conflict is commonly inferred by comparing conditions that consist of two tasks (e.g., congruent and incongruent trials) with conditions that only consist of one task (meaningless non-word neutral trials). In three experiments, we used a color-digit Stroop task that varied in the difficulty of the irrelevant dimension of the stimuli, with these differences explicitly examined in a separate control experiment. While information conflict was evident across all experiments, we found differences in task conflict, so the harder it was to perceive the task-irrelevant dimension, the stronger the task conflict became. These findings demonstrate for the first time that task conflict emerges on a continuum, scaling with the level of engagement or processing demands associated with the irrelevant task. Moreover, these results suggest that our ability to inhibit the involuntary activation of an unwanted process is restricted. Therefore, despite the resource-intensive demands of completing the irrelevant task, it still takes place.

Rocío Hojas, José Norambuena, América Ponce et al.

Abstract Chronic exposure to pesticide residues from large-scale agro-livestock operations remains insufficiently characterized, particularly among rural populations living near industrial pig farming facilities. This study examined the association between co-exposure to organophosphate and pyrethroid pesticide residues in soil and well water and mental health outcomes among adults residing near an industrial pig farming facility in rural Chile. A cross-sectional study was conducted with 82 adults. Peridomestic soil and well water samples were analyzed using gas chromatography–tandem mass spectrometry to detect five pesticides: chlorpyrifos, diazinon, pirimiphos-methyl, cypermethrin, and lambda-cyhalothrin. Mental health outcomes included depressive symptoms, anxiety, emotional affect, and health-related quality of life, assessed with validated instruments. Robust linear regression models were used, adjusting for age, sex, education level, and body mass index. Higher chlorpyrifos concentrations in water were associated with increased depressive symptom scores (β = 0.180; 95% CI: 0.016, 0.345) and lower mental health-related quality of life (β = −0.713; 95% CI: −1.288, − 0.137). Cypermethrin concentrations in water were associated with higher psychological distress (β = 0.324; 95% CI: 0.124, 0.525). In soil, pirimiphos-methyl was positively associated with depressive symptoms (β = 21.29; 95% CI: 1.78, 40.79), whereas cypermethrin showed an inverse association (β = −3.66; 95% CI: −6.99, − 0.33). Lambda-cyhalothrin concentrations in soil were inversely associated with overall quality of life (β = −15.13; 95% CI: −27.42, − 2.84). Male sex was positively associated with overall quality of life (β = 14.96; 95% CI: 3.14, 26.79). These findings indicate associations between environmental pesticide residues in soil and water and multiple dimensions of mental health among rural populations living near industrial pig farming operations. Longitudinal studies are needed to clarify temporal relationships and potential cumulative effects.

Xiaosi Gu, Rick A. Adams

Alfredo Di Lucrezia, Anna Scandurra, Daria Lotito et al.

Abstract In this study, we assessed the interspecific “social buffering effect” of humans on horses, exploring how human presence influences stress responses in horses in an unfamiliar environment using the “isolation paradigm.” We examined nine Haflinger horses under two counterbalanced conditions: with a passive human stranger (social condition) or alone (isolation condition). Stress responses were assessed through cortisol measurements, heart rate monitoring, and behavioral observations. While cortisol levels significantly increased in both conditions, with no notable differences before and after the tests, heart rate data revealed a different pattern. Results indicated that stress generally decreased in both scenarios, impacting heart rate. Initially, during the first five minutes, heart rate was significantly higher in the social condition compared to isolation, but this trend reversed in the following intervals, with heart rate significantly decreasing as interaction with the stranger increased. Positive interaction between time and stranger-directed behaviors suggested the stranger’s influence on heart rate strengthened over time. Overall, these finding suggest that while cortisol data did not reflect a social buffering effect, other metrics indicated that human presence effectively reduced stress in horses after a brief adjustment period, supporting the hypothesis that horses can benefit from human presence during stress, after a short adaptation time. This study highlights the complex nature of stress responses in horses and the potential role of humans as social buffers in interspecific contexts.

Yige Piao, James Brooks, Shinya Yamamoto

Abstract Chimpanzees and bonobos are excellent tool users and can socially learn various skills. Previous studies on social learning mainly measure success/failure in acquiring new techniques, with less direct measurement of proximate mechanisms like visual attention during the process. This study investigates how great apes observe tool-using demonstrations through eye-tracking. After checking initial techniques, six chimpanzees and six bonobos were shown video demonstrations of human demonstrators using a tube to dip (low-efficiency) or suck (high-efficiency) juice, and then tried the task themselves. Attention to each video was compared to participants’ knowledge. Although no individuals acquired the high-efficiency technique through video demonstrations, eye-tracking results revealed attentional differences between individuals familiar with different techniques. Compared with individuals already familiar with both techniques, individuals knowing only the dipping technique showed less attention to the unfamiliar sucking technique. This result indicates that apes may not attend much to what they do not know well, which aligns with reported interplay of action observation and understanding. Attentional patterns to the action part of the two techniques was non-significant between species, though bonobos looked marginally more at faces and chimpanzees looked significantly more at food. This study highlights the importance of conducting detailed investigations into social learning processes, with eye-tracking as one valuable method.

Daniel Poole, James A. Grange, Elizabeth Milne

Autistic people may have a less focused spotlight of spatial selective attention than non-autistic people, meaning that distracting stimuli are less effectively suppressed. Previous studies using the flanker task have supported this suggestion with observations of increased congruency effects in autistic participants. However, findings across studies have been mixed, mainly based on research in children and on response time measures, which may be influenced by differences in response strategy between autistic and non-autistic people rather than differences in selective attention. In this pre-registered study, 153 autistic and 147 non-autistic adults completed an online flanker task. The aims of this study were to test whether increased congruency effects replicate in autistic adults and to extend previous work by fitting a computational model of spatial selective attention on the flanker task to the data. Congruency effects were increased in the autistic group. The modelling revealed that the interference time from the foils was increased in the autistic group. This suggests that the activation of the foils was increased, meaning suppression was less effective for autistic participants. There were also differences in non-interference parameters between the groups. The estimate of response caution was increased in the autistic group and the estimate of perceptual efficiency was decreased. Together these findings suggest inefficient suppression, response strategy and perceptual processing all contribute to differences in performance on the flanker task between autistic and non-autistic people.

Dêverton Plácido Xavier, Filipa Abreu, Antonio Souto et al.

Abstract While foraging, animals have to find potential food sites, remember these sites, and plan the best navigation route. To deal with problems associated with foraging for multiple and patchy resources, primates may employ heuristic strategies to improve foraging success. Until now, no study has attempted to investigate experimentally the use of such strategies by a primate in a context involving foraging in large-scale space. Thus, we carried out an experimental field study that aimed to test if wild common marmosets (Callithrix jacchus) employ heuristic strategies to efficiently navigate through multiple feeding sites distributed in a large-scale space. In our experiment, we arranged four feeding platforms in a trapezoid configuration with up to 60 possible routes and observe marmosets’ decisions under two experimental conditions. In experimental condition I, all platforms contained the same amount of food; in experimental condition II, the platforms had different amounts of food. According to the number and arrangement of the platforms, we tested two heuristic strategies: the Nearest Neighbor Rule and the Gravity Rule. Our results revealed that wild common marmosets prefer to use routes consistent with a heuristic strategy more than expected by chance, regardless of food distribution. The findings also demonstrate that common marmosets seem to integrate different factors such as distance and quantity of food across multiple sites distributed over a large-scale space, employing a combination of heuristic strategies to select the most efficient routes available. In summary, our findings confirm our expectations and provide important insights into the spatial cognition of these small neotropical primates.

Jimena Lois-Milevicich, Lauriane Rat-Fischer, María Alicia de la Colina et al.

Abstract Tool use is taxonomically associated with high behavioural flexibility and innovativeness, and its prevalence is greater in primates and some bird species. This association, however, is not known to be causally determinant of tool-related competence since flexibility and innovativeness are often observed in the absence of tool use and vice versa. For this reason, it is interesting to explore whether animals that can be loosely categorized as outstanding, or ‘intelligent’ physical problem solvers, are also remarkable using tools innovatively, rather than tool use presenting special constraints. We investigate this problem using plush-crested jays (Cyanocorax chrysops), a corvid new to cognitive research that shows highly flexible and inquisitive behaviour in the wild and has not been reported to use tools. We tested jays in two tasks of apparent similar manipulative complexity and incentive, one involving a tool (T) and the other not (NT). In the NT task birds had to open a box with a transparent lid blocked by a latch to get a reward, whereas in the T task, they had to use a rake to pull out the reward from the box. Eight out of nine subjects succeeded in the NT task, whereas none of them learned to solve the T task. This is consistent with tool use involving dedicated competencies, rather than just high problem-solving proficiency.

O.I. Klyuchko

<p style="text-align: justify;"><strong>Objective.</strong> Identification of the potential, approaches and directions of socio-psychological research based on the concept of gender mentality. <strong>Background</strong>. The institutionalization and academicization of gender studies in Russian science is combined with methodological discussions and the active development of terminological apparatus. The use of the concept of gender mentality makes it possible to integrate the basic principles of the gender approach into socio-psychological research, highlight its social context, subject content and levels of analysis. <strong>Methodology.</strong> Concepts of mentality and mentality, the concept of social cognition, social constructivism, methodology of gender studies. <strong>Conclusions</strong>. Understanding mentality as a specificity of group consciousness of people, determined by socio-cultural and spatio-temporal features of the group's life activity, allows us to determine the content of gender mentality as intersubjective, variable and changing social knowledge based on ideas about male and female in culture and society, to identify the content of cognitive, emotional, semantic and behavioral components, as well as its transformation content at the macro, meso and micro levels, using comparative, structural and normative approaches.</p>

Nadia Chernyak, Bertilia Y. Trieu, Tamar Kushnir

Sepehr Mortaheb, Sepehr Mortaheb, Sepehr Mortaheb et al.

Background and Objectives: Persistent post-concussive symptoms (PCS) consist of neurologic and psychological complaints persisting after a mild traumatic brain injury (mTBI). It affects up to 50% of mTBI patients, may cause long-term disability, and reduce patients' quality of life. The aim of this review was to examine the possible use of different neuroimaging modalities in PCS.Methods: Articles from Pubmed database were screened to extract studies that investigated the relationship between any neuroimaging features and symptoms of PCS. Descriptive statistics were applied to report the results.Results: A total of 80 out of 939 papers were included in the final review. Ten examined conventional MRI (30% positive finding), 24 examined diffusion weighted imaging (54.17% positive finding), 23 examined functional MRI (82.61% positive finding), nine examined electro(magneto)encephalography (77.78% positive finding), and 14 examined other techniques (71% positive finding).Conclusion: MRI was the most widely used technique, while functional techniques seem to be the most sensitive tools to evaluate PCS. The common functional patterns associated with symptoms of PCS were a decreased anti-correlation between the default mode network and the task positive network and reduced brain activity in specific areas (most often in the prefrontal cortex).Significance: Our findings highlight the importance to use functional approaches which demonstrated a functional alteration in brain connectivity and activity in most studies assessing PCS.