Hasil untuk "History of Italy"

V. Bauchau, S. Durham

S. Katsanevakis, I. Wallentinus, A. Zenetos et al.

Stelios Katsanevakis*, Inger Wallentinus, Argyro Zenetos, Erkki Leppakoski, Melih Ertan Cinar, Bayram Ozturk, Michal Grabowski, Daniel Golani and Ana Cristina Cardoso European Commission, Joint Research Centre (JRC), Institute for Environment and Sustainability (IES), Ispra, Italy Department of Biological and Environmental Sciences, University of Gothenburg, Sweden Institute of Marine Biological Resources and Inland Waters, Hellenic Centre for Marine Research, Ag. Kosmas, Greece Department of Biosciences, Environmental and Marine Biology, Abo Akademi University, Turku, Finland Ege University, Faculty of Fisheries, Department of Hydrobiology, Bornova, Izmir, Turkey Faculty of Fisheries, Marine Biology Laboratory, University of Istanbul, Istanbul, Turkey Department of Invertebrate Zoology & Hydrobiology, University of Lodz, Poland Department of Ecology, Evolution and Behavior and the National Natural History Collections, The Hebrew University of Jerusalem, Israel

M. Ohayon, T. Roth

L. Montefusco, M. Ben Nasr, F. D’Addio et al.

P. Findlen

In 1500 few Europeans regarded nature as a subject worthy of inquiry. Yet fifty years later the first museums of natural history had appeared in Italy, dedicated to the marvels of nature. Italian patricians, their curiosity fuelled by new voyages of exploration and the humanist rediscovery of nature, created vast collections as a means of knowing the world and used this knowledge to their greater glory. Drawing on extensive archives of visitors' books, letters, travel journals, memoirs, and pleas for patronage, Paula Findlen reconstructs the lost social world of Renaissance and Baroque museums. She follows the new study of natural history as it moved out of the universities and into sixteenth- and seventeenth-century scientific societies, religious orders, and princely courts. Findlen argues convincingly that natural history as a discipline blurred the border between the ancients and the moderns, between collecting in order to recover ancient wisdom and the development of new textual and experimental scholarship. Her vivid account reveals how the scientific revolution grew from the constant mediation between the old forms of knowledge and the new.

M. Jakob, O. Hungr

Peter A. Jałowiczor, Thomas P. Bickle, J. Davy Kirkpatrick et al.

We present new spectroscopic data for Gaia DR3 2309499817384726016 (WD 0008-350A) and its two wide, comoving, low-mass companions. We confirm the white dwarf is a hydrogen rich DA, with T _eff = 6200 ± 90 K and a mass of 0.63 ± 0.03 M _⊙ , close to that of the average white dwarf. Near-infrared spectra of the two stellar companions to WD 0008-350A reveal that the inner companion is an M dwarf, exhibiting a spectral type of M8. Furthermore, the outer companion is identified as a possible M6 + M9 binary. This paper examines the evidence which suggests the system may be quadruple.

N. de Bortoli, Pierfrancesco Visaggi, R. Penagini et al.

Eosinophilic esophagitis (EoE) is a chronic type 2-mediated inflammatory disease of the esophagus that represents the most common eosinophilic gastrointestinal disease. Experts in the field of EoE across Italy (i.e., EoETALY Consensus Group) including gastroenterologists, endoscopists, allergologists/immunologists, and paediatricians conducted a Delphi process to develop updated consensus statements for the management of patients with EoE and update the previous position paper of the Italian Society of Gastroenterology (SIGE) in light of recent evidence. Grading of the strength and quality of the evidence of the recommendations was performed using accepted GRADE criteria. The guideline is divided in two documents: Part 1 includes three chapters, namely 1) definition, epidemiology, and pathogenesis; 2) clinical presentation and natural history, and 3) diagnosis, while Part 2 includes two chapters: 4) treatment and 5) monitoring and follow-up. This document has received the endorsement of three Italian national societies including the SIGE, the Italian Society of Neurogastroenterology and Motility (SINGEM), and the Italian Society of Allergology, Asthma, and Clinical Immunology (SIAAIC). With regards to patients' involvement, these guidelines involved the contribution of members of ESEO Italia, the Italian Association of Families Against EoE.

Koen Stapelbroek

Il volume qui recensito ipotizza che un modo per far conoscere meglio i dibattiti politici sulle riforme economiche negli antichi italiani nel Settecento è quello di studiare i testi del tempo (e i loro contesti) riconoscendovi le influenze straniere. Il metodo proposto appare in effetti una combinazione dei modelli interpretativi di Mario Mirri e di Franco Venturi sul pensiero politico settecentesco. Dal primo provengono l'attenzione per le pratiche politiche e l'astensione da rigidi schemi e categorie interpretative, mentre dal secondo viene assunto un esempio ormai famoso per lo studio della circolazione di testi e idee e delle loro trasformazioni in luoghi e circostanze differenti. Nell'introduzione del volume vengono ricostruiti i due opposti modelli economici che vennero introdotti dalla Francia e dell'Inghilterra, soprattutto dopo 1750, grazie alle traduzioni e alle recensioni nei giornali italiani. Ne emerge un ampio quadro delle oscillazioni negli antichi stati italiani rispetto alle visioni europee di riforma politico-economica. La questione sulla quale il progetto rimane un po' incerto è quella della concettualizzazione dell'idea di emulazione, che in realtà poteva essere indagato, forse nell'introduzione ma soprattutto dagli autori dei saggi, in maniera più approfondita in quanto problema di riforma 'nazionale' e allo stesso momento tipico del sistema interstatale, politico e commerciale.

Andreas N. Angelakis, Andrea G. Capodaglio, Rohitashw Kumar et al.

At the beginning of human history, surface water, especially from rivers and springs, was the most frequent water supply source. Groundwater was used in arid and semi-arid regions, e.g., eastern Crete (Greece). As the population increased, periodic water shortages occurred, which led to the development of sophisticated hydraulic structures for water transfer and for the collection and storage of rainwater, as seen, for example, in Early Minoan times (ca 3200–2100 BC). Water supply and urban planning had always been essentially related: the urban water supply systems that existed in Greece since the Bronze Age (ca 3200–1100 BC) were notably advanced, well organized, and operable. Water supply systems evolved considerably during the Classical and Hellenistic periods (ca 480–31 BC) and during the Roman period (ca 31 BC–480 AD). Also, early Indian society was an amazing vanguard of technology, planning, and vision, which significantly impacted India’s architectural and cultural heritage, thus laying the foundation for sustainable urban living and water resource management. In ancient Egypt, the main source of freshwater was the Nile River; Nile water was conveyed by open and closed canals to supply water to cities, temples, and fields. Underground stone-built aqueducts supplied Nile water to so-called Nile chambers in temples. The evolution of water supply and urban planning approaches from ancient simple systems to complex modern networks demonstrates the ingenuity and resilience of human communities. Many lessons can be learned from studying traditional water supply systems, which could be re-considered for today’s urban sustainable development. By digging into history, measures for overcoming modern problems can be found. Rainwater harvesting, establishing settlements in proximity of water sources to facilitate access to water, planning, and adequate drainage facilities were the characteristics of ancient civilizations since the ancient Egyptian, Minoan, Mohenjo-Daro, Mesopotamian, and Roman eras, which can still be adopted for sustainability. This paper presents significant lessons on water supply around the world from ancient times to the present. This diachronic survey attempts to provide hydro-technology governance for the present and future.

Vittorio Schweiger, Martina Cacciapuoti, Marta Nizzero et al.

Abstract Introduction Pain is one of the most frequently reported symptoms in hemodialyzed (HD) patients, with prevalence rates between 33% and 82%. Risk factors for chronic pain in HD patients are older age, long-lasting dialysis history, several concomitant diseases, malnutrition, and others. However, chronic pain assessment in HD patients is rarely performed by specialists in pain medicine, with relevant consequences in terms of diagnostic and treatment accuracy. Furthermore, no study has used the recently introduced International Association for the Study of Pain (IASP) pathophysiological classification. Methods In this observational, cross-sectional study in a tertiary HD center in Northern Italy, we analyzed data regarding HD patients, evaluated for 5 months in 2021 by specialists in pain medicine and aimed to identify and characterize chronic pain according to the IASP definition and the last 2019 classification of chronic pain for ICD-11. Pain severity was evaluated by the pain severity score of the brief pain inventory tool. Results Among 213 patients, 65 (31%) suffered from chronic pain. The average age was 73.1 years; 55.5% of the patients were male; 53.7% had diabetes, and 39.2% had arterial hypertension. Of the 54 patients subjected to an in-depth evaluation, data regarding 113 pain diagnoses were extracted, particularly related to osteoarthritis, obliterating arterial disease, and low back pain with or without radiculopathy. On the basis of these diagnoses, the pain classification according to the IASP pathophysiological definition highlighted a predominant nociceptive pain type (53.9% of all the diagnoses), followed by neuropathic (22.1%), mixed (22.1%), nociplastic (2.6%), and idiopathic (2.6%) pain. According to the IASP classification for ICD-11, the clinical diagnosis of chronic pain secondary to obliterating arterial disease and diabetes-related foot ulcers could not be assigned to any diagnostic category as a result of the lack of a specific item in the aforementioned classification. Conclusion This study confirmed that chronic pain is a common, burdening issue in hemodialysis patients and that it is of a prevalent nociceptive nature. Our study highlights some limitations of the last IASP ICD-11 classification, especially the lack of specific items for some pain features that are very frequent in hemodialysis patients, and not only in that population. Finally, this study underlines the importance of mutual collaboration between pain physicians and nephrologists for the well-being of patients of high clinical complexity, such as those undergoing chronic hemodialysis.

M. Brunetti, M. Maugeri, F. Monti et al.

Maryam Khazaee-Pool, Tahereh Pashaei, Hossein Rastegar et al.

Abstract Background Health tourism is an important component that may influence the direction of development in a region. Mazandarn, Iran, is recognized as a highly sustainable market in the region because of its abundant natural resources, temperate temperature, and strategic geographical location. Therefore, considering the importance of health tourism and its existing potential in Mazandaran, Iran, this study was conducted with the aim of exploring a comprehensive perspective on local drivers in community-based health tourism industry development and factors affecting the attraction of health tourism. Methods We conducted this study in Mazandarn, Iran, using a qualitative approach. Participants included a sample of Iranian people, aged 34–54 years, with previous history of health tourism or expert in it. Participants were selected from three different categories of the community: academic professionals in health tourism, managers in health tourism, and health tourists. Data were obtained via semi-structured in-depth interviews and focus group discussions. Inductive qualitative content analysis was used to converge and compare themes through participant data. The interviews kept going until data saturation was achieved. Results Based on our findings, we distilled local drivers in community-based health tourism industry development into five main categories and 30 subcategories: (Sharifabadi AM, Ardakani FA. A model for health tourism development using fuzzy TOPSIS and interpretive structural modeling in Yazd province. J Health Adm (JHA). 2014;17:55.) infrastructure and resources; (Hemmati F, Dabbaghi F, Mahmoudi G. Investigating the impact of Information Technology on the status of Health Tourism in Mashhad, Iran. Revista Publicando. 2018;5(15):54–65.) tourist attractions; (Sarabi Asiabar A, Rezapour A, Raei B, Tahernezhad A, Alipour V, Behzadifar M. Economic, Cultural, and Political Requirements for Medical Tourism Development in Iran: Insights from a Fuzzy Analytical Hierarchy Process Method. Med J Islamic Repub Iran. 2022;35:199.) socio-cultural contexts; (Mosadeghrad AM, Sadeghi M. Medical tourism: Reasons for choosing Iran. Payesh (Health Monitor). 2021;20(2):145–66.) economic-financial factors; and (Manna R, Cavallone M, Ciasullo MV, Palumbo R. Beyond the rhetoric of health tourism: shedding light on the reality of health tourism in Italy. Curr Issues Tourism. 2020;23(14):1805–19.) political-communicative factors. The findings of the study showed that, from the participants’ point of view, although there are several strategies, such as the development of public service and tourism infrastructure, increasing tourist attractions, and formulating appropriate policies and procedures for the development of health tourism, they are also faced with many challenges, especially political, economic, and cultural challenges. Conclusion This study showed that improving infrastructure and resources, promoting tourist attractions, informing socio-cultural contexts, improving economic and financial capacity, and developing political and communicative contexts might increase the attraction of health tourists. The suggested components are not contextually driven, although empirical outcomes may differ based on the level of service offerings in health tourism locations.

Bienvenido Martínez-Navarro, Joan Madurell-Malapeira, Sergio Ros-Montoya et al.

On 2015, after the direct study of the most important Late Villafranchian fossil collections of Europe and Western Asia, including Orce (Spain), Pirro Nord and Upper Valdarno (Italy), Appollonia (Greece), Dmanisi (Georgia) and ‘Ubeidiya (Israel), among others, our team proposed the hypothesis that suids disappeared from Europe during the time span between 1.8 and 1.2 Ma. The implications of our conclusions were significant, the arrival of Early <i>Homo</i> into Western Europe, dated to 1.4 Ma at the site of Barranco León in Orce (Spain), preceded the return of pigs into the continent at 1.2 Ma. This hypothesis has been recently challenged because of the finding of an incomplete metatarsal ascribed to <i>Sus</i> sp., with no clear stratigraphic origin, found in the XIX Century Croizet collection of Peyrolles (France), which is housed in the Natural History Museum, London, together with other weak arguments based on the absence of reliable dating for many Early Pleistocene European sites, and other hypothetical records of pigs, with no real fossil support. We answer all these questions and defend that our 2015 hypothesis is correct.

Stefania Cerutti, Siria Moroso

Giardini e turismo, un binomio che riporta a una storia densa e articolata di relazioni ed esperienze che affondano le proprie radici in epoche lontane, secondo modalità di visita e fruizione che hanno sedimentato e definito i contorni del cosiddetto, e più recente, garden tourism. Fenomeno noto e popolare in Europa, prodotto turistico consolidato in Inghilterra e Francia, trova ancora alcune resistenze in Italia in termini di proposte sistemiche e integrate a livello territoriale, rendendo i giardini delle “comparse”, piuttosto che dei “protagonisti”, nello scenario turistico delle destinazioni che cercano tempi e modi rinnovati per attrarre, depolarizzare, destagionalizzare i propri flussi. In questa cornice, il presente contributo si interroga sulla capacità attrattiva e motivazionale dei giardini, eleggendo il caso di studio del Cusio, in Piemonte, quale campo di indagine condotta mediante un sondaggio creato ad hoc. Ciò consente di individuare richieste e percezioni dal lato della domanda turistica e possibili indicazioni da quello dell’offerta, al fine di declinare e promuovere il garden tourism nel contesto del Lago d’Orta, oggetto di indagine. Ne discende che le proposte di turismo dei giardini debbano basarsi su dati e necessità reali, che ne misurino la sostenibilità, ed essere correlate alle aspettative dei visitatori e alle potenzialità delle “risorse verdi” locali, che ne valorizzino il patrimonio.   Gardens and tourism, a combinational pairing that brings back to a dense and articulated history of relationships and experiences rooted in distant epochs, according to visiting and fruition modalities that have sedimented and defined the outlines of the so-called, and more recent, garden tourism. A well-known and popular phenomenon in Europe, a consolidated tourist product in England and France, it still finds some resistance in Italy in terms of systemic and integrated proposals at a territorial level, making gardens “extras” rather than “protagonists” in the tourist scenario of that destinations looking for renewed steps and ways to attract, depolarise and de-seasonalise their flows. In this framework, the paper aims at questioning the attractiveness and motivational capacity of gardens, choosing the case study of Cusio, in Piedmont region, as the field of geographical investigation developed through a survey created ad hoc. This makes it possible to identify requests and perceptions on the tourist demand side and possible suggestions on the supply side, in order to promote the garden tourism in the context of Lake Orta, subject of the survey. It follows that garden tourism proposals have here to be based on real data and needs, which measure their sustainability, and correlate with the expectations of visitors and the potential of local “green resources”, which enhance their heritage.

Serena Marchese, Giacomo Marchese, Giuseppe Paviglianiti et al.

Abstract Background This case of psittacosis in children, is the first described in literature, in Italy. This respiratory infection can be transmitted to humans from the inhalation of respiratory secretions, feces and plumage aerosol of infected birds (and other animals). Usually it can have an asymptomatic or paucisymptomatic course, and the onset is often flu-like, but in this case the child risked his life for a severe respiratory failure. This report is unique because in children psittacosis is rare, and always misdiagnosed, or could cause a delayed diagnosis because of lack of awareness among the paediatricians and physicians. Furthermore, psittacosis enters a differential diagnosis with SARS-COV2 infection because both diseases may determine dyspnea and atypical pneumonia, up to acute respiratory failure. Case presentation This clinical case talks about a three-and-a-half-year-old male child affected by psittacosis (or ornithosis), with severe dyspnea and systemic symptoms who required oro-tracheal intubation for acute respiratory failure. The child had slept in a room at home, with some recently bought parrots affected by psittacosis. Initially the child was treated with empiric antibiotic therapy (i.v.ceftriaxone and teicoplanin), but after having isolated the DNA of the germ “Chlamydia psittaci” in both serological and through bronchoalveolar lavage (BAL), he was treated with targeted antibiotic therapy: tetracyclines (doxicillin). Conclusions Psittacosis is an extremely contagious disease, caused by an intracellular germ, called “Chlamydia psittaci”, a Gram-negative bacterium, transmitted to humans in particular by infected birds, responsible for atypical pneumonia, with acute and chronic respiratory symptoms, sometimes with multi-organ failure and disseminated intravascular coagulation. Even if it is a rare respiratory disease among children, a good doctor must think about psittacosis as cause of respiratory symptoms (and not only flu or SARS-COV2), above all through a correct medical history, in order to provide a targeted antibiotic therapy. An interesting case of psittacosis in a child is being reported here, which has been treated successfully with doxycillin.

Leonardo Salvatore Alaimo, Clio Ciaschini, Francesca Mariani et al.

Abstract Testing density-dependence and path-dependence in long-term population dynamics under differentiated local contexts contributes to delineate the changing role of socioeconomic forces at the base of regional disparities. Despite a millenary settlement history, such issue has been rarely investigated in Europe, and especially in highly divided countries such as those in the Mediterranean region. Using econometric modeling to manage spatial heterogeneity, our study verifies the role of selected drivers of population growth at ten times between 1921 and 2021 in more than 8000 Italian municipalities verifying density-dependent and path-dependent dynamics. Results of global and quantile (spatial) regressions highlight a differential impact of density and (lagged) population growth on demographic dynamics along the urban cycle in Italy. Being weakly significant in the inter-war period (1921–1951), econometric models totalized a high goodness-of-fit in correspondence with compact urbanization (1951–1981). Model’s fit declined in the following decades (1981–2021) reflecting suburbanization and counter-urbanization. Density-dependence and path-dependence were found significant and, respectively, positive or negative, with compact urbanization, and much less intense with suburbanization and counter-urbanization. A spatial econometric investigation of density-dependent and path-dependent mechanisms of population dynamics provided an original explanation of metropolitan cycles, delineating the evolution of socioeconomic (local) systems along the urban-rural gradient.

Y. Tang

Guqin is the Chinese oldest musical instrument and intangible cultural heritage. The Tang Dynasty was the most prosperous in Chinese history, with a flourishing culture. One of the Guqin manufactured by Master Lei Wei, a notable Guqin maker in the Tang Dynasty, was recognized as a reference standard instrument and is kept in the Palace Museum in Beijing. Stradivari, a well-known Italian violin maker, has created and improved violins that no one else can surpass. Triangulation laser and CT/CBCT Scanner-Based 3D modelling data-driven analysis of the ancient musical instrument Guqin from the Tang Dynasty has been compared with the Italy Stradivari violin in a historical review perspective in this paper. After delving into the wood, spatial structure, and other aspects of the Stradivari violin, it has been discovered that the wood, paint, and inner cavity design used by the two masters during their respective heydays are strikingly similar, revealing their shared experience in creating ancient musical instruments in their countries. The bass bar of a Stradivari violin is meant to be transplanted into a Chinese Guqin prototype and get the conclusion that the timbre of the Guqin can be improved according to MATLAB spectrum analysis. This is the first time the two masters from Eastern and Western comparison analysis after the millennium.

Shannan N. Rich, Paola Nasta, Eugenia Quiros-Roldan et al.

Abstract Background Integrase strand transferase inhibitors (INSTI), including raltegravir (RAL), elvitegravir (ELV), and dolutegravir (DTG), have demonstrated better efficacy and tolerability than other combination antiretroviral therapy (cART) classes in clinical trials; however, studies of sustainability of INSTI-containing therapy in the long-term are sparse. The purpose of this study was to provide an epidemiological overview comparing the outcome performance of different INSTI-based regimens longitudinally, including the metrics of efficacy, safety, convenience, and durability among a large, nationally representative cohort of persons living with HIV in Italy. Methods We selected subjects in the MaSTER cohort (an Italian multicenter, hospital-based cohort established in the mid-1990s that currently has enrolled over 24,000 PLWH) who initiated an INSTI-based regimen either when naïve or following a regimen switch. Cox proportional hazards regression models were fitted to evaluate associations between therapy interruptions and age, sex, nationality, transmission risk group, viral suppression status, CD4 + T-cell count, diagnosis year, cART status (naïve or experienced), and hepatitis coinfection. Results were stratified by cART INSTI type. Results There were 8173 participants who initiated an INSTI-based cART regimen in the MaSTER cohort between 2009 and 2017. The population was majority male (72.6%), of Italian nationality (88.6%), and cART-experienced (83.0%). Mean age was 49.7 (standard deviation: 13.9) years. In total, interruptions of the 1st INSTI-based treatment were recorded in 34% of cases. The most frequently cited reason for interruption among all three drug types was safety problems. In the survival analysis, past history of cART use was associated with higher hazards of interruption due to poor efficacy for all three drug types when compared to persons who were cART naïve. Non-viral suppression and CD4 + T-cell count < 200/mm3 at baseline were associated with higher hazards of interruption due to efficacy, safety, and durability reasons. Non-Italian nationality was linked to higher hazards of efficacy interruption for RAL and EVG. Age was negatively associated with interruption due to convenience and positively associated with interruption due to safety reasons. People who injects drugs (PWID) were associated with higher hazards of interruption due to convenience problems. Hepatitis coinfection was linked to higher hazards of interruption due to safety concerns for people receiving RAL. Conclusion One-third of the population experienced an interruption of any drugs included in INSTI therapy in this study. The most frequent reason for interruption was safety concerns which accounted for one-fifth of interruptions among the full study population, mainly switched to DTG. The hazard for interruption was higher for low baseline CD4 + T-cell counts, higher baseline HIV-RNA, non-Italian nationality, older age, PWID and possible co-infections with hepatitis viruses. The risk ratio was higher for past history of cART use compared to persons who were cART naive, use of regimens containing 3 drugs compared to regimens containing 2 drugs. Durability worked in favor of DTG which appeared to perform better in this cohort compared to RAL and EVG, though length of follow-up was significantly shorter for DTG. These observational results need to be confirmed in further perspective studies with longer follow-up.

G. Orsi, S. Vita, M. A. Vito